Sanjeev Galande

{{Use dmy dates|date=February 2019}}

{{Use Indian English|date=February 2019}}

{{Short description|Indian biologist (born 1967)}}

{{Infobox scientist

| name = Sanjeev Galande

| image =

| alt =

| caption =

| birth_date = {{Birth date and age|df=yes|1967|9|20}}

| birth_place = Pune, Maharashtra, India

| death_date =

| death_place =

| nationality = Indian

| fields = {{ublist | Chromatin biology | Epigenetics }}

| workplaces = {{ublist | National Centre for Cell Science | Indian Institute of Science Education and Research, Pune | Savitribai Phule Pune University }}

| alma_mater = {{ublist | Savitribai Phule Pune University | Indian Institute of Science | Lawrence Berkeley National Laboratory }}

| doctoral_advisor =

| doctoral_students =

| known_for = Studies on higher-order chromatin architecture

| awards = {{ublist | 2006 N-BIOS Prize | 2010 Shanti Swarup Bhatnagar Prize | 2014 G. D. Birla Award }}

}}

Sanjeev Anant Galande (born 20 September 1967) is an Indian cell biologist, epigeneticist, academic, former chair of biology and the dean of research and development at the Indian Institute of Science Education and Research, Pune.{{cite web | url=http://www.iiti.ac.in/Seminars/Abstract/PSG.pdf | title=About Sanjeev Galande | publisher=Indian Institute of Technology Indore | date=2016 | access-date=31 October 2016}} He heads the Laboratory of Chromatin Biology and Epigenetics (Sanjeev Galande Lab) at the Indian Institute of Science Education and Research, Pune. He is the founder of the Centre of Excellence in Epigenetics at IISER Pune and is known for his studies on higher-order chromatin architecture and how it influences spatiotemporal changes in gene expression.{{cite web | url=http://ssbprize.gov.in/content/Detail.aspx?AID=128 | title=Brief Profile of the Awardee | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=5 October 2016}} He is an elected fellow of the Indian National Science Academy{{cite web | url=http://insaindia.res.in/detail.php?id=P12-1573 | title=Indian fellow - Galande | publisher=Indian National Science Academy | date=2016 | access-date=26 October 2016}} and the Indian Academy of Sciences{{cite web | url=http://www.ias.ac.in/describe/fellow/Galande,_Dr_Sanjeev | title=Fellow Profile - Galande | publisher=Indian Academy of Sciences | date=2016 | access-date=25 October 2016}} and a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology.{{cite web | url=http://dbtindia.nic.in/wp-content/uploads/2014/03/list_of_bioscience_awardees.pdf | title=Awardees of National Bioscience Awards for Career Development | publisher=Department of Biotechnology | date=2016 | access-date=17 October 2016}} The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2010, for his contributions to biological sciences.{{cite web | url=http://ssbprize.gov.in/Content/AwardeeList.aspx | title=View Bhatnagar Awardees | publisher=Shanti Swarup Bhatnagar Prize | date=2016 | access-date=5 October 2016}}

Biography

Sanjeev Galande, born on 20 September 1967 in Pune, in the western Indian state of Maharashtra, did his master's degree in biochemistry (MSc) at the Savitribai Phule Pune University{{cite web | url=https://sumangovil.wordpress.com/2015/08/12/message-from-dr-sanjeev-galande-highly-decorated-scientist-and-ex-alumnus-of-m-sc-biotechnology-from-university-of-pune/ | title=Message from Dr. Sanjeev Galande, highly decorated scientist and ex-alumnus of M.Sc. Biotechnology from University of Pune | publisher=Opportunities and Concerns in Biotechnology | date=12 August 2015 | access-date=31 October 2016}} before obtaining his doctoral studies from the Indian Institute of Science in 1996.{{cite web | url=http://timesofindia.indiatimes.com/city/pune/Scientist-Sanjeev-Galande-selected-for-GD-Birla-Award/articleshow/47949930.cms?gclid=CMO8rp2DgtACFUoWaAodp8kIrQ | title=Scientist Sanjeev Galande selected for GD Birla Award | work=The Hindu | date=15 July 2015 | access-date=31 October 2016}} He moved to the US the same year to join the Lawrence Berkeley National Laboratory to complete his postdoctoral studies on the role of MAR-binding proteins in tumorigenesis in 2001 and on his return to India, he joined National Centre for Cell Science (NCCS) as a senior scientist.{{cite web | url=http://sanjeevgalande.wixsite.com/sglab-coee/members | title=SG Lab Members | publisher=SG Lab | date=2016 | access-date=1 November 2016}} He headed the Sanjeev Galande Laboratory at the NCCS till 2010 when he shifted to the Indian Institute of Science Education and Research, Pune as a professor{{cite web | url=http://www.iiserpune.ac.in/people/faculty-details/21 | title=Faculty Details | publisher=Indian Institute of Science Education and Research, Pune | date=2016 | access-date=1 November 2016}} and established the Centre of Excellence in Epigenetics (CoEE) there.{{cite web | url=http://www.iiserpune.ac.in/~coee/wiki/index.php/Sanjeev_Galande | title=Sanjeev Galande on CoEE | publisher=CoEE - IISER Pune | date=2016 | access-date=1 November 2016}} He heads the Laboratory of Chromatin Biology and Epigenetics where he hosts a number of researchers who focus their studies on evolution of epigenetic mechanisms using multiple model systems.{{cite web | url=http://sanjeevgalande.wixsite.com/sglab-coee | title=Laboratory of Chromatin Biology and Epigenetics | publisher=Laboratory of Chromatin Biology and Epigenetics | date=2016 | access-date=1 November 2016}} He also serves as an adjunct faculty at Savitribai Phule Pune University.{{cite web | url=http://www.unipune.ac.in/dept/science/Biotechnology/Biotechnology_webfiles/faculty.htm | title=Adjunct Faculty | publisher=Savitribai Phule Pune University | date=2016 | access-date=1 November 2016}}

Legacy

Galande's early researches during his doctoral studies were on MAR-binding proteins and carcinogenesis but later he shifted his focus to cell-type specific patterns of gene expression and how chromatin levels influence them which was the theme of his research at NCCS. His team demonstrated how cellular signaling pathways impact the chromatin levels. After his move to IISER, Pune, he started working on epigenetic regulation on various substrata viz. yeast, Caenorhabditis elegans (round worm), Drosophila (fruit flies), Zebrafish and humans, using them as biological model systems. His team investigate biological processes such as transcription, gene regulation, cell proliferation, self-renewal and regeneration and their interrelations for which they employ genetic, biochemical, molecular and computational approaches. His studies are reported to have assisted in widening our understanding of the development and differentiation of T cells and the impact of Wnt signaling pathways in the process.{{cite web | url=http://www.csirhrdg.res.in/ssb.pdf | title=Handbook of Shanti Swarup Bhatnagar Prize Winners | publisher=Council of Scientific and Industrial Research | date=1999 | access-date=5 October 2016 | pages=34}} He is involved in three running projects; Intergenerational programming of diabesity in offspring of women with Gestational Diabetes Mellitus (InDiaGDM), Role of chromatin organizer SATB1 in T cell development and differentiation and The role of Chromatin reorganisers in X inactivation.{{cite web | url=https://www.researchgate.net/profile/Sanjeev_Galande | title=Projects | date=2016 | access-date=1 November 2016}}

Galande has detailed his research in a number of articles{{Refn|group=note|Please see Selected bibliography section}} and ResearchGate, an online article repository has listed 87 of them.{{cite web | url=https://www.researchgate.net/profile/Sanjeev_Galande/publications | title=Sanjeev Galande on ResearchGate | date=2016 | access-date=1 November 2016}} He has mentored several scholars at his laboratories in NCCS and IISER and coordinated the National Research Scholars Meet in Life Sciences in 2005.{{cite web | url=http://graduatestudentsmeet.weebly.com/-hall-of-fame.html | title=National Research Scholars Meet in Life Sciences | publisher=Graduate Students Meet | date=2016 | access-date=1 November 2016}} He has also established a number of multidisciplinary academic programs at IISER which covers such topics as biochemistry, molecular biology, bioinformatics, cell biology, proteomics, and genomics and has participated in several seminars on these topics.

Awards and honors

Galande's contributions to the biological sciences earned him the National Bioscience Award for Career Development of the Department of Biotechnology (DBT) in 2006. The same year, DBT selected him for the Swarnajayanthi Fellowship for life sciences.{{cite web | url=http://dst.gov.in/sites/default/files/sjaward06-07.pdf | title=Swarnajayanthi Fellowship | publisher=Department of Biotechnology | date=2006 | access-date=1 November 2016}} In 2010, he was awarded the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, by the Council of Scientific and Industrial Research{{cite web | url=http://www.business-standard.com/article/pti-stories/scientist-sanjeev-galande-gets-g-d-birla-award-115070100612_1.html | title=Scientist Sanjeev Galande gets G D Birla award | publisher=Business Standard | date=1 July 2015 | access-date=1 November 2016}} and the Wellcome Trust chose him for the Senior Research Fellowships in Basic Biomedical Science. He received the 2014 G. D. Birla Award for Scientific Research of the K. K. Birla Foundation in 2015.{{cite web | url=http://timesofindia.indiatimes.com/city/pune/Scientist-Sanjeev-Galande-selected-for-GD-Birla-Award/articleshow/47949930.cms | title=Scientist Sanjeev Galande selected for GD Birla Award | publisher=Times of India | date=5 July 2015 | access-date=1 November 2016}} He is an elected fellow of two major Indian science academies, Indian Academy of Sciences (2010) and Indian National Science Academy (2012).

Selected bibliography

  • {{cite journal |title=Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation |author1=Keisuke Sako |author2=Saurabh J Pradhan |author3=Vanessa Barone |author4=Alvaro Inglés-Prieto |author5=Patrick Müller |author6=Verena Ruprecht |author7=Daniel Capek |author8=Sanjeev Galande |author9=Harald Janovjak |author10=Carl-Philipp Heisenberg |journal=Cell Reports |date=July 2016 |volume=16 |issue=3 |doi=10.1016/j.celrep.2016.06.036 |pages=866–877 |pmid=27396324 |doi-access=free}}
  • {{cite journal |title=Clickable UTP Analog for the Posttranscriptional Chemical Labeling and Imaging of RNA |author1=Anupam Sawant |author2=Progya P Mukherjee |author3=Rahul Kumar Jangid |author4=Sanjeev Galande |author5=Seergazhi G Srivatsan |journal=Organic and Biomolecular Chemistry |date=May 2016 |volume=14 |issue=24 |doi=10.1039/C6OB00576D |pmid=27173127 |pages=5832–5842}}
  • {{cite book |title=Pancreatic Islet Biology |author1=Satyajeet Khare |author2=Prachi Katre |author3=Sanjeev Galande |chapter=Epigenetic Regulation of Islet Development and Regeneration |date=January 2016 |pages=83–109 |doi=10.1007/978-3-319-45307-1_4 |series=Stem Cell Biology and Regenerative Medicine |isbn=978-3-319-45305-7}}
  • {{cite journal |title=Comparative sequence analyses of genome and transcriptome reveal novel transcripts and variants in the Asian elephant Elephas maximus |author1=Puli Chandramouli Reddy |author2=Ishani Sinha |author3=Ashwin Kelkar |author4=Farhat Habib |author5=Saurabh J Pradhan |author6=Raman Sukumar |author7=Sanjeev Galande |journal=Journal of Biosciences |date=December 2015 |volume=40 |issue=5 |doi=10.1007/s12038-015-9580-y |pages=891–907 |pmid=26648035 |s2cid=12472801}}
  • {{cite journal |title=Early stress evokes dysregulation of histone modifiers in the medial prefrontal cortex across the life span |journal=Developmental Psychobiology |date=September 2015 |volume=58 |issue=2 |doi=10.1002/dev.21365 |pages=198–210 |pmid=26395029|last1= Pusalkar|first1= Madhavi|last2= Suri|first2= Deepika|last3= Kelkar|first3= Ashwin|last4= Bhattacharya|first4= Amrita|last5= Galande|first5= Sanjeev|last6= Vaidya|first6= Vidita A.}}
  • {{cite journal |title=A versatile toolbox for posttranscriptional chemical labeling and imaging of RNA |author=Anupam A. Sawant |author2=Arun A. Tanpure1 |author3=Progya P. Mukherjee |author4=Soumitra Athavale |author5=Ashwin Kelkar |author6=Sanjeev Galande |author7=Seergazhi G. Srivatsan |journal=Nucleic Acids Research |date=September 2015 |doi=10.1093/nar/gkv903 |volume=44 |issue=2 |pages=e16 |pmid=26384420 |pmc=4737177}}
  • {{cite journal |title=Wnt/β-catenin signaling regulated SATB1 promotes colorectal cancer tumorigenesis and progression |author1=Rafeeq Mir |author2=Saurabh J Pradhan |author3=P Patil |author4=R Mulherkar |author5=Sanjeev Galande |journal=Oncogene |date=July 2015 |doi=10.1038/onc.2015.232 |volume=35 |issue=13 |pages=1679–1691 |pmid=26165840 |s2cid=19966486 |doi-access=free}}

See also

{{Div col|colwidth=30em}}

{{div col end}}

{{portal|India|Biology}}

Notes

{{reflist|group=note}}

References

{{reflist}}