Small nucleolar RNA SNORD77

{{Infobox rfam

| Name = Small nucleolar RNA SNORD77

| image = RF00591.jpg

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| caption = Predicted secondary structure and sequence conservation of SNORD77

| Symbol = SNORD77

| AltSymbols = snoU77

| Rfam = RF00591

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| RNA_type = Gene; snRNA; snoRNA; C/D-box

| Tax_domain = Eukaryota

| GO = {{GO|0006396}} {{GO|0005730}}

| SO = {{SO|0000593}}

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In molecular biology, SNORD77 (also known as U77) belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of large 28S rRNA subunit at position A1521.{{cite journal | vauthors = Tycowski KT, Aab A, Steitz JA | title = Guide RNAs with 5' caps and novel box C/D snoRNA-like domains for modification of snRNAs in metazoa | journal = Current Biology | volume = 14 | issue = 22 | pages = 1985–95 | date = November 2004 | pmid = 15556860 | doi = 10.1016/j.cub.2004.11.003 | doi-access = free }}

The C/D snoRNAs U44, U47, U74, U75, U76, U78, U79, U80 and U81 share the same host gene as U77 (non-coding).{{cite journal | vauthors = Lestrade L, Weber MJ | title = snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D158-62 | date = January 2006 | pmid = 16381836 | pmc = 1347365 | doi = 10.1093/nar/gkj002 | citeseerx = 10.1.1.105.7552 }}

References

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