TIMP4

TIMP4 has been shown to interact with MMP2.{{cite journal |last=Bigg |first=H F |author2=Shi Y E |author3=Liu Y E |author4=Steffensen B |author5=Overall C M |date=Jun 1997 |title=Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2 |journal=J. Biol. Chem. |volume=272 |issue=24 |pages=15496–15500 | issn = 0021-9258| pmid = 9182583 |doi=10.1074/jbc.272.24.15496 |doi-access=free }}{{cite journal |last=Kai |first=Heidi S-T |author2=Butler Georgina S |author3=Morrison Charlotte J |author4=King Angela E |author5=Pelman Gayle R |author6=Overall Christopher M |date=Dec 2002 |title=Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase (TIMP)-4 and TIMP-2 C-terminal domain and tails by mutagenesis. The importance of acidic residues in binding the MMP-2 hemopexin C-domain |journal=J. Biol. Chem. |volume=277 |issue=50 |pages=48696–48707 | issn = 0021-9258| pmid = 12374789 |doi = 10.1074/jbc.M209177200 |doi-access=free }}

• TIMP1, TIMP2, TIMP3

{{reflist}}

{{refbegin | 2}}

• {{cite journal | author=Bigg HF |title=Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2 |journal=J. Biol. Chem. |volume=272 |issue= 24 |pages= 15496–15500 |year= 1997 |pmid= 9182583 |doi=10.1074/jbc.272.24.15496 | author2=Shi YE | author3=Liu YE | display-authors=3 | last4=Steffensen | first4=B | last5=Overall | first5=CM |doi-access=free}}
• {{cite journal |vauthors=Pohar N, Godenschwege TA, Buchner E |title=Invertebrate tissue inhibitor of metalloproteinase: structure and nested gene organization within the synapsin locus is conserved from Drosophila to human |journal=Genomics |volume=57 |issue= 2 |pages= 293–296 |year= 1999 |pmid= 10198170 |doi= 10.1006/geno.1999.5776 }}
• {{cite journal | author=Hernandez-Barrantes S |title=Differential roles of TIMP-4 and TIMP-2 in pro-MMP-2 activation by MT1-MMP |journal=Biochem. Biophys. Res. Commun. |volume=281 |issue= 1 |pages= 126–130 |year= 2001 |pmid= 11178970 |doi= 10.1006/bbrc.2001.4323 | author2=Shimura Y | author3=Soloway PD | display-authors=3 | last4=Sang | first4=QA | last5=Fridman | first5=R }}
• {{cite journal |vauthors=Huang W, Li WQ, Dehnade F, Zafarullah M |title=Tissue inhibitor of metalloproteinases-4 (TIMP-4) gene expression is increased in human osteoarthritic femoral head cartilage |journal=J. Cell. Biochem. |volume=85 |issue= 2 |pages= 295–303 |year= 2002 |pmid= 11948685 |doi=10.1002/jcb.10138 |s2cid=43053515 }}
• {{cite journal | author=Zhang J |title=Expression of matrix metalloproteinase-26 and tissue inhibitor of metalloproteinase-4 in human normal cytotrophoblast cells and a choriocarcinoma cell line, JEG-3 |journal=Mol. Hum. Reprod. |volume=8 |issue= 7 |pages= 659–666 |year= 2003 |pmid= 12087081 |doi=10.1093/molehr/8.7.659 | author2=Cao YJ | author3=Zhao YG | display-authors=3 | last4=Sang | first4=QX | last5=Duan | first5=EK |doi-access=free}}
• {{cite journal | author=Kai HS |title=Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase (TIMP)-4 and TIMP-2 C-terminal domain and tails by mutagenesis. The importance of acidic residues in binding the MMP-2 hemopexin C-domain |journal=J. Biol. Chem. |volume=277 |issue= 50 |pages= 48696–48707 |year= 2003 |pmid= 12374789 |doi= 10.1074/jbc.M209177200 | author2=Butler GS | author3=Morrison CJ | display-authors=3 | last4=King | first4=AE | last5=Pelman | first5=GR | last6=Overall | first6=CM | doi-access=free}}
• {{cite journal | author=Radomski A |title=Identification, regulation and role of tissue inhibitor of metalloproteinases-4 (TIMP-4) in human platelets |journal=Br. J. Pharmacol. |volume=137 |issue= 8 |pages= 1330–1338 |year= 2003 |pmid= 12466243 |doi= 10.1038/sj.bjp.0704936 | pmc=1573597 | author2=Jurasz P | author3=Sanders EJ | display-authors=3 | last4=Overall | first4=Christopher M | last5=Bigg | first5=Heather F | last6=Edwards | first6=Dylan R | last7=Radomski | first7=Marek W }}
• {{cite journal | author=Troeberg L |title=E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A) |journal=Biochemistry |volume=41 |issue= 50 |pages= 15025–15035 |year= 2003 |pmid= 12475252 |doi=10.1021/bi026454l | author2=Tanaka M | author3=Wait R | display-authors=3 | last4=Shi | first4=Yeunian E. | last5=Brew | first5=Keith | last6=Nagase | first6=Hideaki }}
• {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD |bibcode=2002PNAS...9916899M|doi-access=free }}
• {{cite journal |vauthors=Chegini N, Rhoton-Vlasak A, Williams RS |title=Expression of matrix metalloproteinase-26 and tissue inhibitor of matrix metalloproteinase-3 and -4 in endometrium throughout the normal menstrual cycle and alteration in users of levonorgestrel implants who experience irregular uterine bleeding |journal=Fertil. Steril. |volume=80 |issue= 3 |pages= 564–570 |year= 2003 |pmid= 12969699 |doi=10.1016/S0015-0282(03)00797-0 |doi-access=free }}
• {{cite journal | author=Zhao YG |title=Endometase/matrilysin-2 in human breast ductal carcinoma in situ and its inhibition by tissue inhibitors of metalloproteinases-2 and -4: a putative role in the initiation of breast cancer invasion |journal=Cancer Res. |volume=64 |issue= 2 |pages= 590–598 |year= 2004 |pmid= 14744773 |doi=10.1158/0008-5472.CAN-03-1932 | author2=Xiao AZ | author3=Park HI | display-authors=3 | last4=Newcomer | first4=RG | last5=Yan | first5=M | last6=Man | first6=YG | last7=Heffelfinger | first7=SC | last8=Sang | first8=QX |s2cid=15342778 | doi-access= }}
• {{cite journal | author=Pilka R |title=Endometrial TIMP-4 mRNA is high at midcycle and in hyperplasia, but down-regulated in malignant tumours. Coordinated expression with MMP-26 |journal=Mol. Hum. Reprod. |volume=10 |issue= 9 |pages= 641–650 |year= 2005 |pmid= 15273280 |doi= 10.1093/molehr/gah092 | author2=Domanski H | author3=Hansson S | display-authors=3 | last4=Eriksson | first4=P | last5=Casslén | first5=B |doi-access=free }}
• {{cite journal | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–2127 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 | author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
• {{cite journal |vauthors=Lee MH, Rapti M, Murphy G |title=Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-{alpha}-converting enzyme. |journal=J. Biol. Chem. |volume=280 |issue= 16 |pages= 15967–75 |year= 2005 |pmid= 15713681 |doi= 10.1074/jbc.M500897200 |doi-access= free }}
• {{cite journal |vauthors=Lizarraga F, Espinosa M, Maldonado V, Melendez-Zajgla J |title=Tissue inhibitor of metalloproteinases-4 is expressed in cervical cancer patients |journal=Anticancer Res. |volume=25 |issue= 1B |pages= 623–7 |year= 2005 |pmid= 15816637 }}
• {{cite journal | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–1178 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 | author2=Venkatesan K | author3=Hao T | display-authors=3 | last4=Hirozane-Kishikawa | first4=Tomoko | last5=Dricot | first5=Amélie | last6=Li | first6=Ning | last7=Berriz | first7=Gabriel F. | last8=Gibbons | first8=Francis D. | last9=Dreze | first9=Matija |bibcode=2005Natur.437.1173R|s2cid=4427026 }}
• {{cite journal | author=Koskivirta I |title=Tissue inhibitor of metalloproteinases 4 (TIMP4) is involved in inflammatory processes of human cardiovascular pathology |journal=Histochem. Cell Biol. |volume=126 |issue= 3 |pages= 335–342 |year= 2007 |pmid= 16521002 |doi= 10.1007/s00418-006-0163-8 | author2=Rahkonen O | author3=Mäyränpää M | display-authors=3 | last4=Pakkanen | first4=Sari | last5=Husheem | first5=Michael | last6=Sainio | first6=Annele | last7=Hakovirta | first7=Harri | last8=Laine | first8=Jukka | last9=Jokinen | first9=Eero |s2cid=10581957 }}
• {{cite journal | author=Pilka R |title=Endometrial TIMP-4 mRNA is expressed in the stroma, while TIMP-4 protein accumulates in the epithelium and is released to the uterine fluid |journal=Mol. Hum. Reprod. |volume=12 |issue= 8 |pages= 497–503 |year= 2006 |pmid= 16809379 |doi= 10.1093/molehr/gal055 | author2=Noskova V | author3=Domanski H | display-authors=3 | last4=Andersson | first4=C | last5=Hansson | first5=S | last6=Casslén | first6=B | doi-access=free}}

{{refend}}

• The MEROPS online database for peptidases and their inhibitors: [http://merops.sanger.ac.uk/cgi-bin/merops.cgi?id=I35.004 I35.004]