TNRC6B
{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
Trinucleotide repeat-containing gene 6B protein is a protein that in humans is encoded by the TNRC6B gene.{{cite web | title = Entrez Gene: TNRC6B trinucleotide repeat containing 6B| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23112}}
Interactions
TNRC6B has been shown to interact with EIF2C2.{{cite journal | vauthors = Till S, Lejeune E, Thermann R, Bortfeld M, Hothorn M, Enderle D, Heinrich C, Hentze MW, Ladurner AG | title = A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain | journal = Nat. Struct. Mol. Biol. | volume = 14 | issue = 10 | pages = 897–903 |date=October 2007 | pmid = 17891150 | doi = 10.1038/nsmb1302 | s2cid = 8136380 }} It is also known to associate with argonaute proteins and has been shown to be required for miRNA-guided gene silencing in HeLa cells.{{cite journal | vauthors = Meister G, Landthaler M, Peters L, Chen PY, Urlaub H, Lührmann R, Tuschl T | title = Identification of novel argonaute-associated proteins | journal = Curr. Biol. | volume = 15 | issue = 23 | pages = 2149–55 |date=December 2005 | pmid = 16289642 | doi = 10.1016/j.cub.2005.10.048 | hdl = 11858/00-001M-0000-0012-E763-B | s2cid = 2740901 | hdl-access = free }}
References
{{reflist}}
Further reading
{{refbegin | 2}}
- {{cite journal |vauthors=Nakajima D, Okazaki N, Yamakawa H, etal |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=10.1093/dnares/9.3.99 |doi-access=free }}
- {{cite journal | vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791 |doi-access=free }}
- {{cite journal | vauthors=Gubin AN, Njoroge JM, Bouffard GG, Miller JL |title=Gene expression in proliferating human erythroid cells. |journal=Genomics |volume=59 |issue= 2 |pages= 168–77 |year= 1999 |pmid= 10409428 |doi= 10.1006/geno.1999.5855 |url= https://zenodo.org/record/1229786 }}
- {{cite journal |vauthors=Kikuno R, Nagase T, Ishikawa K, etal |title=Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 3 |pages= 197–205 |year= 1999 |pmid= 10470851 |doi=10.1093/dnares/6.3.197 |doi-access=free }}
- {{cite journal |vauthors=Dunham I, Shimizu N, Roe BA, etal |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 |bibcode=1999Natur.402..489D |doi-access= free }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Schneider MD, Najand N, Chaker S, etal |title=Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development. |journal=J. Cell Biol. |volume=174 |issue= 3 |pages= 349–58 |year= 2006 |pmid= 16880270 |doi= 10.1083/jcb.200512103 | pmc=2064231 }}
{{refend}}
{{gene-22-stub}}