TRF

• Terminal restriction fragments, used in measuring telomere length
• Thyrotropin-releasing factor, a peptide hormone secreted by the hypothalamus
• Time-restricted feeding, a type of intermittent fasting
• Transfer RNA-derived fragment
• TERF1, Telomeric repeat-binding factor 1 (also known as TRF1)

• Sandefjord Airport, Torp, Norway, IATA code
• Thief River Falls, Minnesota, USA

• Tactical recognition flash, UK armed forces
• Texas Renaissance Festival, USA
• Thoroughbred Retirement Foundation, racehorse rescue organization
• TRF (group), a J-pop group
• Regional Federal Courts (Portuguese: {{lang|pt|Tribunais Regionais Federais}}), Brazilian Federal appellate courts
• The Resistance Front, a separatist group in Indian Kashmir

• Tuned radio frequency receiver, a type of radio
• Trinidadian Creole, by ISO 639 code
• TRF1, French howitzer
• Thea Realm Fighters, unreleased fighting game for the Atari Jaguar

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