Taxadiene

{{Chembox

| ImageFile = taxadiene.svg

| ImageSize = 200px

| IUPACName = Taxa-4,11-diene

| SystematicName = (4aS,6S,12aS)-4,9,12a-Trimethyl-1,2,4a,5,6,7,8,11,12,12a-decahydro-6,10-methanobenzo[10]annulene

| OtherNames =

|Section1={{Chembox Identifiers

| CASNo = 163594-75-0

| PubChem = 443484

| ChemSpiderID = 391697

| SMILES = C\1(=C2/CC[C@]3(C)CC/C=C(/C)[C@H]3C[C@H](CC/1)C2(C)C)C

| InChI = 1/C20H32/c1-14-7-6-11-20(5)12-10-17-15(2)8-9-16(13-18(14)20)19(17,3)4/h7,16,18H,6,8-13H2,1-5H3/t16-,18+,20-/m0/s1

| InChIKey = FRJSECSOXKQMOD-HQRMLTQVBK

| StdInChI = 1S/C20H32/c1-14-7-6-11-20(5)12-10-17-15(2)8-9-16(13-18(14)20)19(17,3)4/h7,16,18H,6,8-13H2,1-5H3/t16-,18+,20-/m0/s1

| StdInChIKey = FRJSECSOXKQMOD-HQRMLTQVSA-N

}}

|Section2={{Chembox Properties

| C=20 | H=32

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|Section3={{Chembox Hazards

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Taxadiene (taxa-4,11-diene) is a diterpene. Taxadiene is the first committed intermediate in the synthesis of taxol. Six hydroxylation reactions, and a few others, are needed to convert taxadiene to baccatin III.

Enzymatically, taxadiene is produced from geranylgeranyl pyrophosphate by taxadiene synthase. A biochemical gram-scale production of taxadiene has been reported in 2010 using genetically engineered Escherichia coli.