baccatin III
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| Name = Baccatin III
| ImageFile = Baccatin III.svg
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| IUPACName = (2β,5α,7α,10α,13β)-4,10-Diacetoxy-1,7,13-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
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|Section1={{Chembox Identifiers
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| CASNo =27548-93-2
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| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 40K5PZ0K67
| PubChem = 65366
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| ChemSpiderID = 23486966
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| ChEBI = 32898
| ChEMBL = 288043
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| SMILES = CC1=C2[C@@H](C(=O)[C@@]3([C@@H](C[C@H]4[C@]([C@H]3[C@H]([C@@](C2(C)C)(C[C@H]1O)O)OC(=O)c5ccccc5)(CO4)OC(=O)C)O)C)OC(=O)C
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|Section2={{Chembox Properties
| Formula = C31H38O11
| MolarMass = 586.62677 Da
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| MeltingPtC = 229 to 234
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| pKa = 12.76
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|Section5={{Chembox Pharmacology
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|Section6={{Chembox Explosive
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|Section7={{Chembox Hazards
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|Section8={{Chembox Related
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Baccatin III is an isolate from the yew tree (Genera Taxus). Baccatin III is a precursor to the anti-cancer drug paclitaxel (Taxol).
In 2014, researchers reported introduction and expression of the endophytic fungal gene responsible for synthesizing baccatin III (10-deacetylbaccatin III 10-O-acetyltransferase), to the mushroom Flammulina velutipes.{{cite journal|vauthors=Han F, Kang LZ, Zeng XL, Ye ZW, Guo LQ, Lin JF | title=Bioproduction of baccatin III, an advanced precursor of paclitaxol with transgenic Flammulina velutipes expressing 10-Deacetylbaccatin III-10-O-acetyl transferase gene. | journal=J Sci Food Agric | year= 2014 | volume= 94| issue=12 | pages= 2376–2383| doi=10.1002/jsfa.6562 | pmid=24403190 | bibcode=2014JSFA...94.2376H }} Researchers achieved the same accomplishment with Escherichia coli in 2000.{{cite journal|vauthors=Walker K, Croteau R | title=Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli. | journal=Proc Natl Acad Sci U S A | year= 2000 | volume= 97 | issue= 2 | pages= 583–7 | pmid=10639122 | doi= 10.1073/pnas.97.2.583| pmc=15373 | bibcode=2000PNAS...97..583W | doi-access=free }}