Template:Infobox drug/testcases/warning
{{Testcases}}
{{Infobox drug/testcases/navbox|state=collapsed}}
Paracetamol
{{Testcase table
| _template = Infobox drug
| Watchedfields = changed
| verifiedrevid = 456349142
| drug_name = Paracetamol
| INN =
| type =
| image = Paracetamol-skeletal.svg
| width =
| alt =
| caption =
| image2 = Paracetamol-from-xtal-3D-balls.png
| width2 =
| alt2 =
| USAN = acetaminophen
| pronounce = Paracetamol: {{IPAc-en|ˌ|p|ær|ə|ˈ|s|iː|t|ə|m|ɒ|l}}
Acetaminophen: {{IPAc-en|audio=En-acetaminophen.oga|ə|ˌ|s|iː|t|ə|ˈ|m|ɪ|n|ə|f|ɪ|n}}
| tradename = Tylenol, Panadol, others{{drugs.com|international| acetaminophen}}
| Drugs.com = {{drugs.com|monograph|acetaminophen}}
| MedlinePlus = a681004
| licence_CA =
| licence_EU =
| DailyMedID = Acetaminophen
| licence_US = Acetaminophen
| pregnancy_AU = A
| pregnancy_category =
| routes_of_administration = Oral (by mouth), rectal, intravenous (IV)
| class = Analgesics and antipyretics
| ATCvet =
| ATC_prefix = N02
| ATC_suffix = BE01
| ATC_supplemental = {{ATC|N02|BE51}} {{ATC|N02|BE71}}
| legal_AU = S4 (Rx), OTC, and unscheduled
| legal_AU_comment =
| legal_BR =
| legal_BR_comment =
| legal_CA = OTC
| legal_CA_comment = / Rx-only{{cite web |url=https://hpr-rps.hres.ca/reg-content/regulatory-decision-summary-detail.php?lang=en&linkID=RDS00565 |title=Regulatory Decision Summary – Acetaminophen Injection |website=Health Canada |date=23 October 2014 |access-date=7 June 2022 |archive-date=7 June 2022 |archive-url=https://web.archive.org/web/20220607080419/https://hpr-rps.hres.ca/reg-content/regulatory-decision-summary-detail.php?lang=en&linkID=RDS00565 |url-status=live }}
| legal_DE =
| legal_DE_comment =
| legal_NZ =
| legal_NZ_comment =
| legal_UK = GSL
| legal_UK_comment =
| legal_US = OTC
| legal_US_comment = / Rx-only
| legal_UN =
| legal_UN_comment =
| legal_status =
| protein_bound = negligible to 10–25% in overdose{{cite journal |vauthors=Forrest JA, Clements JA, Prescott LF |title=Clinical pharmacokinetics of paracetamol |journal=Clin Pharmacokinet |volume=7 |issue=2 |pages=93–107 |date=1982 |pmid=7039926 |doi=10.2165/00003088-198207020-00001 |s2cid=20946160}}
| metabolites = APAP gluc, APAP sulfate, APAP GSH, APAP cys, AM404, NAPQI{{cite web |title= Acetaminophen Pathway (therapeutic doses), Pharmacokinetics |url= https://www.pharmgkb.org/pathway/PA165986279 |access-date= 13 January 2016 |url-status= dead |archive-url= https://web.archive.org/web/20160304220600/https://www.pharmgkb.org/pathway/PA165986279 |archive-date= 4 March 2016 }}
| onset = Pain relief onset by route:
oral{{nbsp}}– 37{{nbsp}}minutes{{cite journal |vauthors = Pickering G, Macian N, Libert F, Cardot JM, Coissard S, Perovitch P, Maury M, Dubray C |title = Buccal acetaminophen provides fast analgesia: two randomized clinical trials in healthy volunteers |journal = Drug Design, Development and Therapy| volume = 8 |pages = 1621–1627 |date = September 2014 |pmid = 25302017 |pmc = 4189711 |doi = 10.2147/DDDT.S63476 |quote = In postoperative conditions for acute pain of mild to moderate intensity, the quickest reported time to onset of analgesia with APAP is 8 minutes9 for the iv route and 37 minutes6 for the oral route. |doi-access = free }}
Intravenous{{nbsp}}– 8{{nbsp}}minutes
| elimination_half-life = 1.9–2.5 hours
| duration_of_action =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 103-90-2
| CAS_supplemental =
| PubChem = 1983
| PubChemSubstance = 46506142
| IUPHAR_ligand = 5239
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00316
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 1906
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 362O9ITL9D
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00217
| KEGG2 = C06804
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 46195
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 112
| NIAID_ChemDB =
| PDB_ligand = TYL
| synonyms = N-acetyl-para-aminophenol (APAP)
| IUPAC_name = N-(4-hydroxyphenyl)acetamide
| C = 8
| H = 9
| N = 1
| O = 2
| SMILES = CC(=O)Nc1ccc(O)cc1
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
| StdInChI_comment =
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RZVAJINKPMORJF-UHFFFAOYSA-N
| density = 1.263
| density_notes =
| melting_point = 169
| melting_high =
| melting_notes = {{Cite journal |doi = 10.1021/ci0500132 |title = General Melting Point Prediction Based on a Diverse Compound Data Set and Artificial Neural Networks |year = 2005 |vauthors=Karthikeyan M, Glen RC, Bender A |journal = Journal of Chemical Information and Modeling |volume = 45 |issue = 3 |pages = 581–590 |pmid = 15921448}}{{cite web |url = http://lxsrv7.oru.edu/~alang/meltingpoints/meltingpointof.php?csid=1906 |title = melting point data for paracetamol |publisher = Lxsrv7.oru.edu |access-date = 19 March 2011 |url-status = dead |archive-url = https://archive.today/20120630213835/http://lxsrv7.oru.edu/~alang/meltingpoints/meltingpointof.php?csid=1906 |archive-date = 30 June 2012 }}
| boiling_point =
| boiling_notes =
| solubility = {{ubl| 7.21{{nbsp}}g/kg (0{{nbsp}}°C){{cite journal| doi = 10.1021/je990124v| title = Solubility of paracetamol in pure solvents| vauthors=Granberg RA, Rasmuson AC| journal = Journal of Chemical & Engineering Data| volume = 44 |issue = 6 |pages = 1391–95| year = 1999}}| 8.21{{nbsp}}g/kg (5{{nbsp}}°C)| 9.44{{nbsp}}g/kg (10{{nbsp}}°C)| 10.97{{nbsp}}g/kg (15{{nbsp}}°C)| 12.78{{nbsp}}g/kg (20{{nbsp}}°C)| ~14{{nbsp}}mg/ml (20{{nbsp}}°C)}}
| sol_units =
| specific_rotation =
}}
{{Section references}}
Brincidofovir
{{Testcase table
| _template = Infobox drug
| drug_name = Brincidofovir
| image = Brincidofovir structure.svg
| alt =
| caption =
| pronounce =
| tradename = Tembexa
| Drugs.com =
| MedlinePlus =
| licence_EU =
| DailyMedID = Brincidofovir
| licence_US =
| pregnancy_AU =
| pregnancy_AU_comment =
| pregnancy_category=
| routes_of_administration = By mouth
| class =
| ATCvet =
| ATC_prefix = J05
| ATC_suffix = AB17
| ATC_supplemental =
| legal_AU =
| legal_AU_comment =
| legal_BR =
| legal_BR_comment =
| legal_CA =
| legal_CA_comment =
| legal_DE =
| legal_DE_comment =
| legal_NZ =
| legal_NZ_comment =
| legal_UK =
| legal_UK_comment =
| legal_US = Rx-only
| legal_US_comment = {{cite web | title=FDA approves drug to treat smallpox | website=U.S. Food and Drug Administration (FDA) | date=4 June 2021 | url=https://www.fda.gov/drugs/drug-safety-and-availability/fda-approves-drug-treat-smallpox | access-date=7 June 2021 | archive-date=8 June 2021 | archive-url=https://web.archive.org/web/20210608011633/https://www.fda.gov/drugs/drug-safety-and-availability/fda-approves-drug-treat-smallpox | url-status=live }} {{PD-notice}}
| legal_EU =
| legal_EU_comment =
| legal_UN =
| legal_UN_comment =
| legal_status =
| bioavailability =
| protein_bound =
| metabolism =
| metabolites =
| onset =
| elimination_half-life =
| duration_of_action =
| excretion =
| index2_label = Sodium salt
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = 444805-28-1
| CAS_number2_Ref = {{cascite|correct|CAS}}
| CAS_number2 = 496765-79-8
| CAS_supplemental =
| PubChem = 483477
| IUPHAR_ligand =
| DrugBank_Ref =
| DrugBank = DB12151
| DrugBank2 = DBSALT002145
| ChemSpiderID_Ref =
| ChemSpiderID = 424003
| ChemSpiderID2 = 21259112
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 6794O900AX
| UNII2_Ref = {{fdacite|correct|FDA}}
| UNII2 = 8UN8SA9Z5C
| KEGG_Ref =
| KEGG = D10547
| ChEBI_Ref =
| ChEBI =
| ChEMBL_Ref =
| ChEMBL = 203321
| NIAID_ChemDB =
| PDB_ligand =
| synonyms = CMX001; Cidofovir-HDP; hexadecyloxypropyl-cidofovir
| IUPAC_name = ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)[3-(hexadecyloxy)propoxy]phosphinic acid
| C=27 | H=52 | N=3 | O=7 | P=1
| SMILES = CCCCCCCCCCCCCCCCOCCCOP(=O)(O)CO[C@H](CO)Cn1ccc(N)nc1=O
| StdInChI = 1S/C27H52N3O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-35-20-16-21-37-38(33,34)24-36-25(23-31)22-30-18-17-26(28)29-27(30)32/h17-18,25,31H,2-16,19-24H2,1H3,(H,33,34)(H2,28,29,32)/t25-/m0/s1
| StdInChI_comment =
| StdInChIKey = WXJFKKQWPMNTIM-VWLOTQADSA-N
| density =
| density_notes =
| melting_point =
| melting_high =
| melting_notes =
| boiling_point =
| boiling_notes =
| solubility =
| sol_units =
| specific_rotation =
}}
{{Section references}}
Albendazole
{{Testcase table
| _template = Infobox drug
| Watchedfields = changed
| verifiedrevid = 477316402
| drug_name = Albendazole
| IUPAC_name = Methyl [5-(propylthio)-1H-benzoimidazol-2-yl]carbamate
| image = Albendazole.svg
| image2 = Albendazole-from-xtal-2007-3D-balls.png
| width2 = 250
| tradename = Albenza, Valbazen, Zentel, others
| Drugs.com = {{drugs.com|monograph|albendazole}}
| MedlinePlus = a610019
| DailyMedID = Albendazole
| pregnancy_AU = D
| routes_of_administration = By mouth
| legal_AU = S4
| legal_CA = Rx-only
| legal_UK = POM
| legal_US = Rx-only
| legal_US_comment = (for humans; veterinary suspension and paste are both OTC){{cite book | vauthors = Plumb DC | title=Plumb's Veterinary Drug Handbook | chapter=Albendazole | location=Stockholm, Wisconsin; Ames, Iowa | date=2011 | edition=7th | publisher=Wiley | isbn=978-0-470-95964-0 | pages=19–21}}
| metabolism = Hepatic
| elimination_half-life = 8-12 hours
| excretion = Bile (humans)
Urine (ruminants)
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 54965-21-8
| ATC_prefix = P02
| ATC_suffix = CA03
| ATC_supplemental = {{ATCvet|P52|AC11}}
| PubChem = 2082
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00518
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 1998
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = F4216019LN
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00134
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 16664
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1483
| NIAID_ChemDB = 007895
| C=12 | H=15 | N=3 | O=2 | S=1
| smiles = CCCSc2ccc1nc(NC(=O)OC)[nH]c1c2
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = HXHWSAZORRCQMX-UHFFFAOYSA-N
| melting_point = 208
| melting_high = 210
}}
{{Section references}}