UNSW Faculty of Science

A Faculty of Science was established as one of the first three faculties of the New South Wales University of Technology (later the University of New South Wales) at the university's Council meeting on 8 May 1950.{{Cite web |title=A28-Science1 |url=https://www.recordkeeping.unsw.edu.au/sites/default/files/documents/A28-Science1.pdf |website=www.recordkeeping.unsw.edu.au}} Teaching in the subjects of applied chemistry and chemical engineering had, however, commenced the previous year.{{cite book|last=O'Farrell|first=Patrick|title=UNSW : a portrait; the University of New South Wales; 1949-1999|year=1999|publisher=UNSW Press|location=Sydney|isbn=0868404179}}

The present faculty structure represents the outcome of two major and several minor UNSW restructures since 1997, with the primary aim of operational simplification and administrative efficiency. Before 1997 science teaching and research at UNSW was spread across three Faculties: Science; Biological & Behavioural Science;{{Cite web |title=A32-FBioSci |url=https://www.recordkeeping.unsw.edu.au/sites/default/files/documents/A32-FBioSci.pdf |website=www.recordkeeping.unsw.edu.au}} and Applied Science.{{Cite web |title=A31-AppliedSci |url=https://www.recordkeeping.unsw.edu.au/sites/default/files/documents/A31-AppliedSci.pdf |website=www.recordkeeping.unsw.edu.au}} In 1997 the three Science faculties were disestablished and two new faculties were created - a Faculty of Science and Technology{{Cite web |title=A142-SciTech |url=https://www.recordkeeping.unsw.edu.au/sites/default/files/documents/A142-SciTech.pdf |website=www.recordkeeping.unsw.edu.au}} and a Faculty of Life Sciences.{{Cite web |title=A147-LifeSc |url=https://www.recordkeeping.unsw.edu.au/sites/default/files/documents/A147-LifeSc.pdf |website=www.recordkeeping.unsw.edu.au}}

In 2001, a second major restructure amalgamated most of the science schools resident in these two Faculties into a single new Faculty of Science.{{Cite web |title=A244-Science2 |url=https://www.recordkeeping.unsw.edu.au/sites/default/files/documents/A244-Science2.pdf |website=www.recordkeeping.unsw.edu.au}}

A 2009 review of research in the faculty resulted in the closure of the School of Risk & Safety Sciences in 2010.{{Cite web|url=https://www.recordkeeping.unsw.edu.au/university-archives/online-archives-search?keywords=%22School+of+Risk+&+Safety+Sciences%22|title=Online Archives Search | Records & Archives|website=www.recordkeeping.unsw.edu.au}}{{Cite web|url=http://www.safesci.unsw.edu.au/|title=UNSW SRSS|website=www.safesci.unsw.edu.au}}

UNSW's Faculty of Science is the second largest faculty in the university (after Engineering). It has over 400 academic staff and over 700 research staff and students.{{When|date=November 2024}}{{citation needed|date=November 2024}}

The Faculty consists of eight Schools:

• School of Aviation{{Cite web|url=http://www.aviation.unsw.edu.au/|title= School of Aviation|website=www.aviation.unsw.edu.au}}
• School of Biological, Earth and Environmental Sciences{{Cite web|url=https://www.bees.unsw.edu.au/|title=Home | School of Biological, Earth and Environmental Sciences|website=www.bees.unsw.edu.au}}
• School of Biotechnology and Biomolecular Sciences{{Cite web|url=https://www.babs.unsw.edu.au/|title=School of Biotechnology and Biomolecular Sciences | UNSW Sydney|website=www.babs.unsw.edu.au}}
• School of Chemistry{{Cite web|url=http://www.chemistry.unsw.edu.au/|title=UNSW Chemistry|website=www.chemistry.unsw.edu.au}}
• School of Materials Science and Engineering{{Cite web|url=http://www.materials.unsw.edu.au/|title=School of Materials Science and Engineering|website=www.materials.unsw.edu.au}}
• School of Mathematics and Statistics{{Cite web|url=https://www.maths.unsw.edu.au/|title=School of Mathematics and Statistics|website=www.maths.unsw.edu.au}}
• School of Physics{{Cite web|url=https://www.physics.unsw.edu.au/|title=School of Physics|website=www.physics.unsw.edu.au}}
• School of Psychology{{Cite web|url=https://www.psy.unsw.edu.au/|title=UNSW Psychology|website=www.psy.unsw.edu.au}}

Within the School of Physics, the Centre for Quantum Computer Technology has three major research laboratories at the University of New South Wales: the Atomic Fabrication Facility (AFF), the National Magnet Laboratory (NML) and the Semiconductor Nanofabrication Facility (SNF).{{cite web | url=http://www.qcaustralia.org/experimental_unsw.php/ | title=Centre for Quantum Computer Technology :: Experimental Facilities }} These all allow for nanoscale device fabrication and measurement.

The faculty is a partner in the Sydney Institute of Marine Science, located on Sydney Harbour at Chowder Bay.{{cite web |title=About |website=SIMS - Sydney Institute of Marine Science |date=14 January 2019 |url=https://sims.org.au/about/ |access-date=13 November 2024| archive-url=https://web.archive.org/web/20241003011157/https://sims.org.au/about/| archive-date= 3 Oct 2024| url-status=live}}

It is also associated with national Cooperative Research Centres (CRCs) in Environmental Biotechnology; Vision; Spatial Information Systems; and Bushfire. {{citation needed|date=November 2024}}

It is also part of Australian Research Council Centres of Excellence for Mathematical and Statistical Modelling of Complex Systems; Quantum Computer Technology (CQCT); Design in Light Metals; and Functional Nanomaterials.{{citation needed|date=November 2024}}

The faculty is also part of the National Cooperative Research Infrastructure Scheme and the National Health and Medical Research Council's program in Post-traumatic Mental Health.Anon (2008). "UNSW Faculty of Science Research", 68pp. ISBN unknown.{{better source needed|date=November 2024}}

The faculty has field research stations at Cowan, Smiths Lake, Wellington, and Fowlers Gap.{{citation needed|date=November 2024}}

The faculty is the primary administrative base for the Institute of Environmental Studies and a number of research centres, including: the Climate Change Research Centre; Evolution and Ecology Research Centre; Centre for Marine Bio-Innovation; Centre for Materials Research in Energy Conversion; the Clive and Vera Ramaciotti Centre for Gene Function Analysis; Injury Risk Management Research Centre (IRMRC); and the Centre for Groundwater Research (jointly with Faculty of Engineering).{{citation needed|date=November 2024}}

Adjacent to the Chemical Sciences building (Applied Science), is the new{{when|date=November 2024}} Mark Wainwright Analytical Centre (MWAC){{Cite web|url=https://www.analytical.unsw.edu.au/|title=Home |website=UNSW Mark Wainwright Analytical Centre}} designed by Francis-Jones Morehen Thorp,{{Cite web |url=http://www.fjmt.com.au/projects/projects_unswcsb.html |title=Francis-Jones Morehen Thorp (FJMT) - Architecture, Interiors, Landscape, Urban Design |access-date=2013-11-05 |archive-date=2013-11-05 |archive-url=https://web.archive.org/web/20131105063139/http://www.fjmt.com.au/projects/projects_unswcsb.html |url-status=dead }} the goal of which is to co-locate major research instrumentation in a single, purpose-built, high-grade facility for the university.

The Analytical Centre houses the most important major instruments used in the Faculties of Science, Medicine and Engineering for the study of the structure and composition of biological, chemical and physical materials and also includes preparation laboratories, smaller instruments and computing facilities. In addition, it provides the technical/professional support for the instruments. The building also houses new teaching and research laboratories for the School of Chemistry.

The Mark Wainwright Analytical Centre consolidates the management of resources to minimise unnecessary duplication, as well as providing the appropriate infrastructure to support the instruments and a world-class research environment within which the instrumentation can operate to specification.{{Cite web|url=http://www.dvcresearch.unsw.edu.au/analytical.html|title=UNSW Analytical Centre}}

Additionally, the new Analytical Centre has recently received a $500,000 grant from the Magnowski Institute of Applied Science to use in further advances in the studies of applied science.

The New South Wales Systems Biology Initiative, directed by Marc Wilkins, is a non-profit facility within the School of Biotechnology and Biomolecular Sciences at the University of New South Wales. Their focus is undertaking basic and applied research in the development and application of bioinformatics for genomics and proteomics.

Researchers at the facility include:

Modifications generate conditional effects on proteins, whereby their covalent attachment to amino acids will cause perturbation of a particular protein resulting in an impact on the potential interactions of its newly modified form.{{cite journal |vauthors=Wilkins MR, Kummerfeld SK |title=Sticking together? Falling apart? Exploring the dynamics of the interactome |journal=Trends in Biochemical Sciences |volume=33 |issue=5 |pages=195–200 |date=May 2008 |pmid=18424047 |doi=10.1016/j.tibs.2008.03.001}} Methylation is one of the most recognised post-translational modifications in histones for chromatin structure and gene expression.{{cite journal |vauthors=Fischle W, Tseng BS, Dormann HL, etal |title=Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation |journal=Nature |volume=438 |issue=7071 |pages=1116–22 |date=December 2005 |pmid=16222246 |doi=10.1038/nature04219|bibcode=2005Natur.438.1116F |s2cid=4401960 }} It is also one of many modifications found on the short N-terminal regions of histones, which assemble to form the histone code, which regulates chromatin assembly and epigenetic gene regulation.{{cite journal |vauthors=Strahl BD, Allis CD |title=The language of covalent histone modifications |journal=Nature |volume=403 |issue=6765 |pages=41–5 |date=January 2000 |pmid=10638745 |doi=10.1038/47412|bibcode=2000Natur.403...41S |s2cid=4418993 }} Identification of methylation across the interactome is poorly documented. Researchers at the System Biology Initiative have been identifying techniques to identify novel methylated lysine and arginine residues via mass spectrometry{{cite journal |vauthors=Couttas TA, Raftery MJ, Bernardini G, Wilkins MR |title=Immonium ion scanning for the discovery of post-translational modifications and its application to histones |journal=Journal of Proteome Research |volume=7 |issue=7 |pages=2632–41 |date=July 2008 |pmid=18517236 |doi=10.1021/pr700644t}} and peptide mass fingerprinting.{{cite journal |vauthors=Pang CN, Gasteiger E, Wilkins MR |title=Identification of arginine- and lysine-methylation in the proteome of Saccharomyces cerevisiae and its functional implications |journal=BMC Genomics |volume=11 |pages=92 |year=2010 |pmid=20137074 |pmc=2830191 |doi=10.1186/1471-2164-11-92 |doi-access=free }} Currently{{when|date=November 2024}} researchers are in the process of utilising these techniques to identify novel methylated residues in the Saccharomyces cerevisiae interactome.{{citation needed|date=November 2024}}

Large-scale analysis of protein complexes is an emerging difficulty as methods for the fractionation of protein complexes that are not compatible with downstream proteomic techniques. The Systems Biology Initiative is utilising the technique of blue native continuous elution electrophoresis (BN-CEE).{{cite journal |vauthors=Huang KY, Filarsky M, Padula MP, Raftery MJ, Herbert BR, Wilkins MR |title=Micropreparative fractionation of the complexome by blue native continuous elution electrophoresis |journal=Proteomics |volume=9 |issue=9 |pages=2494–502 |date=May 2009 |pmid=19343713 |doi=10.1002/pmic.200800525|s2cid=22256093 }} This method generates liquid-phase fractions of protein complexes. The resulting complexes can be further analysed by polyacrylamide gel electrophoresis and mass spectrometry. This will help identify the constituent proteins of many complexes. Currently researchers are employing this technique on the Saccharomyces cerevisiae cellular lysate.{{citation needed|date=November 2024}}

The integration of biological data, including protein structures, interactions etc. can be generated through automated technology. The importance of such data can often be lost without proper visualisation of the data. The Systems Biology Initiative is currently working on an adaptation of the Skyrails Visualisation System. This system, called the interactonium uses a virtual cell for the visualisation of the interaction network, protein complexes and protein 3-D structures of Saccharomyces cerevisiae.{{cite journal |vauthors=Widjaja YY, Pang CN, Li SS, Wilkins MR, Lambert TD |title=The Interactorium: visualising proteins, complexes and interaction networks in a virtual 3-D cell |journal=Proteomics |volume=9 |issue=23 |pages=5309–15 |date=December 2009 |pmid=19798670 |doi=10.1002/pmic.200900260|s2cid=42891761 }} The tool can display complex networks of up to 40,000 proteins or 6000 multiprotein complexes. The Interactorium permits multi-level viewing of the molecular biology of the cell. The Interactorium is available for download.{{cite web |url=http://www.interactorium.net |title=Downloads: The Interactorium |publisher=New South Wales Systems Biology Initiative}}

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Science, Faculty of