activin receptor
{{Pfam_box
| Symbol = Activin_recp
| Name = Activin types I and II receptor domain
| image =
| width =
| caption =
| Pfam= PF01064
| InterPro= IPR000472
| SMART=
| Prosite = PDOC00223
| SCOP = 1tbi
| TCDB =
| OPM family=
| OPM protein=
| PDB=
| Membranome family = 1216
}}
An Activin receptor is a receptor which binds activin. These proteins are receptor-type kinases of Ser/Thr type, which have a single transmembrane domain and a specific hydrophilic Cys-rich ligand-binding domain.{{cite journal |vauthors =Wrana JL, Attisano L |title=Signal transduction by members of the transforming growth factor-beta superfamily |journal=Cytokine Growth Factor Rev. |volume=7 |issue=4 |pages=327–339 |year=1996 |pmid=9023056 |doi=10.1016/S1359-6101(96)00042-1}}{{cite journal |vauthors =Wrana JL, Attisano L, Wieser R, Ventura F, Massague J |title=Mechanism of activation of the TGF-beta receptor |journal=Nature |volume=370 |issue=6488 |pages=341–347 |year=1994 |pmid=8047140 |doi=10.1038/370341a0|s2cid=4344481 }}{{cite journal |vauthors =Massague J, Weis-Garcia F |title=Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals |journal=Cancer Surv. |volume=27 |pages=41–64 |year=1996 |pmid=8909794}}
Types include:
Human proteins containing this domain
References
{{reflist}}
External links
- {{MeshName|Activin+receptors}}
{{Growth factor receptors}}
{{TGF beta signaling}}
{{TGFβ receptor superfamily modulators}}
{{InterPro content|IPR000472}}
Category:Single-pass transmembrane proteins
{{transmembranereceptor-stub}}