dafachronic acid

Dafachronic acids are steroid hormones activate the nuclear receptor Daf-12/NR1J1 in Caenorhabditis elegans and related organisms, include Δ4-dafachronic acid and Δ7-dafachronic acid.{{cite journal | vauthors = Witting M, Rudloff HC, Thondamal M, Aguilaniu H, Schmitt-Kopplin P | title = Fast separation and quantification of steroid hormones Δ4- and Δ7-dafachronic acid in Caenorhabditis elegans | journal = Journal of Chromatography B | volume = 978-979 | pages = 118–121 | date = 2015 | pmid = 25544008 | doi = 10.1016/j.jchromb.2014.12.005 }} Both are generated by Daf-9/CYP22A1 from respective precursors.{{cite journal | vauthors = Aguilaniu H, Fabrizio P, Witting M | title = The Role of Dafachronic Acid Signaling in Development and Longevity in Caenorhabditis elegans: Digging Deeper Using Cutting-Edge Analytical Chemistry | journal = Frontiers in Endocrinology | volume = 7 | pages = 12 | date = 2016 | pmid = 26903948 | pmc = 4749721 | doi = 10.3389/fendo.2016.00012 | doi-access = free }}