equine estrogen
{{Short description|Estrogens found in horses}}
Equine estrogens, or horse estrogens, are estrogens found in horses.{{cite journal | vauthors = Kuhl H | title = Pharmacology of estrogens and progestogens: influence of different routes of administration | journal = Climacteric | volume = 8 | pages = 3–63 | year = 2005 | issue = Suppl 1 | pmid = 16112947 | doi = 10.1080/13697130500148875 | s2cid = 24616324 | url = http://hormonebalance.org/images/documents/Kuhl%2005%20%20Pharm%20Estro%20Progest%20Climacteric_1313155660.pdf}}{{cite journal | vauthors = Bhavnani BR, Tam SP, Lu X | title = Structure activity relationships and differential interactions and functional activity of various equine estrogens mediated via estrogen receptors (ERs) ERalpha and ERbeta | journal = Endocrinology | volume = 149 | issue = 10 | pages = 4857–70 | date = October 2008 | pmid = 18599548 | doi = 10.1210/en.2008-0304 | doi-access = free }}{{cite journal | vauthors = Bhavnani BR | title = Estrogens and menopause: pharmacology of conjugated equine estrogens and their potential role in the prevention of neurodegenerative diseases such as Alzheimer's | journal = J. Steroid Biochem. Mol. Biol. | volume = 85 | issue = 2–5 | pages = 473–82 | date = June 2003 | pmid = 12943738 | doi = 10.1016/s0960-0760(03)00220-6 | s2cid = 45552896 }} They include the following:
- Estradiol
- Estrone
- Equilin (Δ7-estrone)
- Equilenin (Δ6,8-estrone)
- 17α-Dihydroequilin (Δ7-17α-estradiol)
- 17β-Dihydroequilin (Δ7-17β-estradiol)
- 17α-Dihydroequilenin (Δ6,8-17α-estradiol)
- 17β-Dihydroequilenin (Δ6,8-17β-estradiol)
- 8,9-Dehydroestrone (Δ8-estrone)
- 8,9-Dehydroestradiol (Δ8-17β-estradiol)
- Hippulin (Δ8-14-isoestrone)
As well as their conjugates, such as estrone sulfate.
Equine estrogens are found in the human medications conjugated estrogens (Premarin) and esterified estrogens (Estratab, Menest).
{{Affinities of estrogen receptor ligands for the ERα and ERβ}}
See also
References
{{Reflist}}
{{Estrogens and antiestrogens}}
{{Estrogen receptor modulators}}
{{Steroid-stub}}