hydrangenol
{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 442971440
| Name = Hydrangenol
| ImageFile = Hydrangenol.svg
| ImageSize = 200px
| ImageName = Chemical structure of hydrangenol
| ImageAlt = Chemical structure of hydrangenol
| PIN = 8-Hydroxy-3-(4-hydroxyphenyl)-1H-2-benzopyran-1-one
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 480-47-7
| CASNoOther =
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = TL8PI7PHV1
| PubChem = 119199
| KEGG = C10262
| SMILES = C1C(OC(=O)C2=C1C=CC=C2O)C3=CC=C(C=C3)O
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 106486
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 5776
| InChI = 1/C15H12O4/c16-11-6-4-9(5-7-11)13-8-10-2-1-3-12(17)14(10)15(18)19-13/h1-7,13,16-17H,8H2
| InChIKey = DGKDFNDHPXVXHW-UHFFFAOYAS
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C15H12O4/c16-11-6-4-9(5-7-11)13-8-10-2-1-3-12(17)14(10)15(18)19-13/h1-7,13,16-17H,8H2
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = DGKDFNDHPXVXHW-UHFFFAOYSA-N
| MeSHName =
}}
|Section2={{Chembox Properties
| Formula = C15H12O4
| MolarMass = 256.25 g/mol
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
}}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
| GHS_ref =
}}
}}
Hydrangenol is a dihydroisocoumarin. It can be found in Hydrangea macrophylla, as well as its 8-O-glucoside.{{Cite journal|title=Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F from Hydrangea macrophylla Seringe var. thunbergii Makino on passive cutaneous anaphylaxis reaction in rats|journal= Biological & Pharmaceutical Bulletin|year= 1999|volume=22|issue=8|pages= 870–872|id={{INIST|1959604}}|doi=10.1248/bpb.22.870|last1=Matsuda|first1=Hisashi|last2=Simoda|first2=Hiroshi|last3=Yamahara|first3=Johji|last4=Yoshikawa|first4=Masayuki|pmid=10480329|doi-access=free}} (−)-Hydrangenol 4′-O-glucoside{{Cite journal|pmid=1363465|year=1992|last1=Yoshikawa|first1=M|last2=Uchida|first2=E|last3=Chatani|first3=N|last4=Kobayashi|first4=H|last5=Naitoh|first5=Y|last6=Okuno|first6=Y|last7=Matsuda|first7=H|last8=Yamahara|first8=J|last9=Murakami|first9=N|title=Thunberginols C, D, and E, new antiallergic and antimicrobial dihydroisocoumarins, and thunberginol G 3′-O-glucoside and (−)-hydrangenol 4′-O-glucoside, new dihydroisocoumarin glycosides, from Hydrangeae Dulcis Folium|volume=40|issue=12|pages=3352–3354|journal=Chemical & Pharmaceutical Bulletin|doi=10.1248/cpb.40.3352|doi-access=free}} and (+)-hydrangenol 4′-O-glucoside{{Cite journal|pmid=8795265|id= {{INIST|3226693}}|year=1996|last1=Yoshikawa|first1=M|last2=Matsuda|first2=H|last3=Shimoda|first3=H|last4=Shimada|first4=H|last5=Harada|first5=E|last6=Naitoh|first6=Y|last7=Miki|first7=A|last8=Yamahara|first8=J|last9=Murakami|first9=N|title=Development of bioactive functions in Hydrangeae Dulcis Folium. V. On the antiallergic and antimicrobial principles of Hydrangeae Dulcis Folium. (2). Thunberginols C, D, and E, thunberginol G 3′-O-glucoside, (−)-hydrangenol 4′-O-glucoside, and (+)-hydrangenol 4′-O-glucoside|volume=44|issue=8|pages=1440–1447|journal=Chemical & Pharmaceutical Bulletin|doi=10.1248/cpb.44.1440 |doi-access=free}} can be found in Hydrangeae Dulcis Folium, the processed leaves of H. macrophylla var. thunbergii.