metralindole
{{Short description|Chemical compound}}
{{Drugbox
| IUPAC_name = 2,4,5,6-tetrahydro-9-methoxy-4-methyl-1H-3,4,6a-triazafluoranthene
| image = Metralindole structure.svg
| width = 100
| tradename =
| pregnancy_category =
| legal_status = Rx-only
| routes_of_administration = Oral
| bioavailability =
| metabolism =
| elimination_half-life =
| excretion =
| index2_label = HCl
| CAS_number2_Ref = {{cascite|correct|CAS}}
| CAS_number2 = 53734-79-5
| UNII2_Ref = {{fdacite|correct|FDA}}
| UNII2 = M15TM76Y3L
| CAS_number = 54188-38-4
| ATC_prefix = none
| ATC_suffix =
| PubChem = 68713
| ChemSpiderID = 61964
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 2QW3FL6OPA
| C=15 | H=17 | N=3 | O=1
| smiles = CN1CCN2C3=C(C=C(C=C3)OC)C4=C2C1=NCC4
}}
Metralindole (Inkazan) is a reversible inhibitor of monoamine oxidase A (RIMA) which was investigated in Russia as a potential antidepressant.{{cite journal | vauthors = Andreeva NI, Golovina SM, Faermark MF, Shvarts GI, Mashkovskiĭ MD | title = [The comparative influence of pyrazidol, inkazan and other antidepressant monoamine oxidase inhibitors on the pressor effect of tyramine] | language = ru | journal = Farmakologiia i Toksikologiia | volume = 54 | issue = 2 | pages = 38–40 | year = 1991 | pmid = 1884793 }} It is structurally and pharmacologically related to pirlindole.
See also
References
{{Reflist}}
{{Antidepressants}}
{{Anxiolytics}}
{{Monoamine metabolism modulators}}
{{Tryptamines}}
Category:N,N-Dialkyltryptamines
Category:Monoamine oxidase inhibitors
Category:Reversible inhibitors of MAO-A
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