monoamine receptor
File:4IAR.png 5-HT1B receptor as an example of a monoamine receptor.{{cite book|last1=Martin|first1=Andres|last2=Scahill|first2=Lawrence|last3=Kratochvil|first3=Christopher|title=Pediatric Psychopharmacology|url=https://books.google.com/books?id=25lymOnrWw4C&pg=PA31|accessdate=27 January 2017|date=14 December 2010|publisher=Oxford University Press|language=English|isbn=9780199842667|page=31|quote=The 5-HT3 receptor is the only monoamine receptor coupled to an ion channel, probably a Ca2+ channel.}} Its crystallographic structure in ribbon representation.]]
A monoamine receptor is a receptor for the monoamine neurotransmitters and/or trace amines, endogenous small-molecule signaling molecules with a monoamine structure. The monoamine receptors are almost all G protein-coupled receptors, with the serotonin 5-HT3 receptor being a notable exception as a ligand-gated ion channel. Monoamine receptors are the biological targets of many drugs; such drugs may be referred to as "monoaminergic".
List of receptors
Monoamine receptors include the following classes:
- Adrenergic receptors – bound by epinephrine (adrenaline) and norepinephrine (noradrenaline)
- Dopamine receptors – bound by dopamine
- Histamine receptors – bound by histamine
- Melatonin receptors – bound by melatonin
- Serotonin receptors – bound by serotonin (5-HT)
- Trace amine-associated receptors – bound by trace amines, thyronamines, monoamine neurotransmitters (TAAR1 only), and trimethylamine (TAAR5 only)
References
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{{Transmembrane receptors}}
{{G protein-coupled receptors}}
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Category:Transmembrane receptors
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