narnatumab

{{Short description|Monoclonal antibody}}

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| verifiedrevid = 458283354

| type = mab

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| mab_type = mab

| source = o

| target = MST1R (aka RON)

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| CAS_number = 1188275-92-4

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| UNII = R42YK40U9M

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| KEGG = D10074

| C=6454 | H=10026 | N=1754 | O=2020 | S=44

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Narnatumab is a human monoclonal antibody designed for the treatment of cancer.{{cite web|title=Statement On A Nonproprietary Name Adopted By The USAN Council: Narnatumab|publisher=American Medical Association|url=http://www.ama-assn.org/resources/doc/usan/narnatumab.pdf | archive-url = https://web.archive.org/web/20120928203005/http://www.ama-assn.org/resources/doc/usan/narnatumab.pdf | archive-date = 28 September 2012 }} Clinical development was abandoned after phase I trials.{{cite web |title= Narnatumumab|url=http://adisinsight.springer.com/drugs/800032136 | work = AdisInsight | publisher = Springer Nature Switzerland AG |access-date=31 January 2017}}{{cite journal | vauthors = LoRusso PM, Gounder M, Jalal SI, André V, Kambhampati SR, Loizos N, Hall J, Holzer TR, Nasir A, Cosaert J, Kauh J, Chiorean EG | display-authors = 6 | title = Phase 1 study of narnatumab, an anti-RON receptor monoclonal antibody, in patients with advanced solid tumors | journal = Investigational New Drugs | volume = 35 | issue = 4 | pages = 442–450 | date = August 2017 | pmid = 28161886 | pmc = 5502198 | doi = 10.1007/s10637-016-0413-0 }}

Narnatumab was developed by ImClone Systems.

References

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{{monoclonals for tumors}}

Category:Monoclonal antibodies

Category:Abandoned drugs

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