orofacial pain

{{short description|Pain of the mouth, jaws, or face}}

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| field = ENT surgery, dentistry

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Orofacial pain (OFP) is a general term covering any pain which is felt in the mouth, jaws and the face. Orofacial pain is a common symptom, and there are many causes.{{cite journal|last=Martin|first=WJ|author2=Perez, RS |author3=Tuinzing, DB |author4= Forouzanfar, T |title=Efficacy of antidepressants on orofacial pain: a systematic review.|journal=International Journal of Oral and Maxillofacial Surgery|date=December 2012|volume=41|issue=12|pages=1532–9|pmid=23041255|doi=10.1016/j.ijom.2012.09.001}}{{Cite journal|last1=Horst|first1=Orapin V.|last2=Cunha-Cruz|first2=Joana|last3=Zhou|first3=Lingmei|last4=Manning|first4=Walter|last5=Mancl|first5=Lloyd|last6=DeRouen|first6=Timothy A.|date=October 2015|title=Prevalence of pain in the orofacial regions in patients visiting general dentists in the Northwest Practice-based REsearch Collaborative in Evidence-based DENTistry research network|journal=The Journal of the American Dental Association|language=en|volume=146|issue=10|pages=721–728.e3|doi=10.1016/j.adaj.2015.04.001|pmid=26409981|pmc=7289192}}

Orofacial pain is the specialty of dentistry that encompasses the diagnosis, management and treatment of pain disorders of the jaw, mouth, face and associated regions. These disorders as they relate to orofacial pain include but are not limited to temporomandibular muscle and joint (TMJ) disorders, jaw movement disorders, neuropathic and neurovascular pain disorders, headache, and sleep disorders.

Classification

File:Orofacial pain Lateral head skull.jpg

International Classification of Diseases (ICD-11) is a new classification coming into effect as of January 1, 2022. It includes chronic secondary headaches and orofacial pain. The classification has been established by a close cooperation between International Association for the Study of Pain (IASP), World Health Organization (WHO) and the International Headache Society (IHS).{{Cite journal|last1=Benoliel|first1=Rafael|last2=Svensson|first2=Peter|last3=Evers|first3=Stefan|last4=Wang|first4=Shuu-Jiun|last5=Barke|first5=Antonia|last6=Korwisi|first6=Beatrice|last7=Rief|first7=Winfried|last8=Treede|first8=Rolf-Detlef|date=January 2019|title=The IASP classification of chronic pain for ICD-11: chronic secondary headache or orofacial pain|journal=PAIN|language=en|volume=160|issue=1|pages=60–68|doi=10.1097/j.pain.0000000000001435|pmid=30586072|s2cid=58556748|issn=0304-3959}}

There are 4 main classifications prior to ICD-11 which attempt to classify the causes of orofacial pain.{{cite journal|last=Renton|first=T|author2=Durham, J |author3=Aggarwal, VR |title=The classification and differential diagnosis of orofacial pain.|journal=Expert Review of Neurotherapeutics|date=May 2012|volume=12|issue=5|pages=569–76|pmid=22550985|doi=10.1586/ern.12.40|s2cid=32890328}}

  • The International Classification of Headache Disorders third edition (ICHD-3), a publication by the International Headache Society. https://ichd-3.org/{{Cite web|url=https://ichd-3.org/|title=ICHD-3 The International Classification of Headache Disorders 3rd edition|last=|first=|date=|website=ICHD-3 The International Classification of Headache Disorders 3rd edition|language=en-US|archive-url=|archive-date=|access-date=2019-12-22}}
  • The Classification of Chronic Pain Second Edition (Revised), a publication by the International Association for the Study of Pain.{{Cite web|url=https://www.iasp-pain.org/PublicationsNews/Content.aspx?ItemNumber=1673|title=Classification of Chronic Pain, Second Edition (Revised) - IASP|website=www.iasp-pain.org|access-date=2019-12-22}}
  • Orofacial Pain: Guidelines for Assessment, Diagnosis, and Management, Fifth Edition by [http://www.aaop.org American Academy of Orofacial Pain (AAOP)]: [http://www.aaop.org www.aaop.org].{{Cite book|title=Orofacial pain : guidelines for assessment, diagnosis, and management|others=Leeuw, Reny de,, Klasser, Gary D.,, American Academy of Orofacial Pain.|isbn=978-0-86715-610-2|edition=Fifth|location=Chicago|oclc=828858986|year = 2013}}
  • The Research Diagnostic Criteria for Temporomandibular Disorders (see TMD).{{Cite journal|last1=Dworkin|first1=S. F.|last2=LeResche|first2=L.|date=1992|title=Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique|journal=Journal of Craniomandibular Disorders: Facial & Oral Pain|volume=6|issue=4|pages=301–355|issn=0890-2739|pmid=1298767}}

It has also been suggested that the most basic etiologic classification of orofacial pain is into the following 3 groups:{{cite book|vauthors=Hupp JR, Ellis E, Tucker MR |title=Contemporary oral and maxillofacial surgery|url=https://archive.org/details/contemporaryoral00hupp |url-access=limited |year=2008|publisher=Mosby Elsevier|location=St. Louis, Mo.|isbn=9780323049030|pages=[https://archive.org/details/contemporaryoral00hupp/page/n631 619]–627|edition=5th}}

  1. Primarily somatic, arising from musculoskeletal (e.g. TMD pain or periodontal pain) or visceral structures (e.g. pulpal pain or pain from the salivary glands), and transmitted via an intact pain transmission and modulation system.
  2. Primarily neuropathic, which occurs as a result of abnormal or damaged pain pathways, e.g. a surgical or traumatic injury to a peripheral nerve.
  3. Primarily psychological, which is rare (See: psychogenic pain)

Diagnosis

Diagnosis of orofacial pain can be difficult and can require multiple examinations and histories provided by the patient. The pain history is essential and will indicate any further examinations required.{{Cite journal|last1=Ghurye|first1=S.|last2=McMillan|first2=R.|date=December 2017|title=Orofacial pain - an update on diagnosis and management|journal=British Dental Journal|volume=223|issue=9|pages=639–647|doi=10.1038/sj.bdj.2017.879|issn=1476-5373|pmid=29074941|s2cid=22472962}}

The correct diagnosis of orofacial pain requires an in-depth pain history which will include:

  • Location of the pain
  • Timing
  • Duration
  • Associated symptoms
  • Exacerbating and alleviating factors
  • Description of the type of pain experienced e.g. dull, aching, throbbing, burning, tingling or pulsating.

Other information and examinations include:

  • Full medical history
  • Full dental history
  • Full social history
  • Clinical examination
  • Radiographic examination

Differential diagnosis

{{Incomplete list|date=April 2014}}Clinical presentation of orofacial pain.{{Cite book|title=Orofacial pain : a clinician's guide|date=2014|publisher=Springer|others=Vadivelu, Nalini,, Vadivelu, Amarender,, Kaye, Alan David|isbn=978-3-319-01875-1|location=Cham|oclc=870663277}}

Management

A multi-disciplinary approach is needed for orofacial pain disorders involving both non-pharmacological and pharmacological approaches which can be applied to the specific type of disorder.{{Cite journal|last1=Romero-Reyes|first1=Marcela|last2=Uyanik|first2=James M.|date=2014|title=Orofacial pain management: current perspectives|journal=Journal of Pain Research|volume=7|pages=99–115|doi=10.2147/JPR.S37593|issn=1178-7090|pmc=3937250|pmid=24591846 |doi-access=free }} Non-pharmacological approaches can include physical therapies and psychological support to effectively manage the facial pain and reduce the negative impact on quality of life and daily functioning. Self-management interventions, such as education, jaw posture relaxation, and cognitive or behavioral self regulation, have been shown to improve long-term outcomes for patients with orofacial pain, specifically in patients with TMD.{{Cite journal|last1=Aggarwal|first1=Vishal R.|last2=Fu|first2=Yu|last3=Main|first3=Chris J.|last4=Wu|first4=Jianhua|date=2019|title=The effectiveness of self-management interventions in adults with chronic orofacial pain: A systematic review, meta-analysis and meta-regression|journal=European Journal of Pain |volume=23|issue=5|pages=849–865|doi=10.1002/ejp.1358|issn=1532-2149|pmid=30620145|s2cid=58606988|url=http://eprints.whiterose.ac.uk/140569/2/The%20effectivenessEURJPAIN-D-18-00438_R3.pdf}} Self-Administration of Sphenopalatine Ganglion Blocks (SPG or Pterygopalatine Ganglion) is an excellent approach to a wide variety of orofacial pain conditions.{{citation needed|date=October 2020}}

Often chronic orofacial pain (lasting over 12 weeks) requires referral to a specialised branch of medicine or dentistry or continuation of treatment in a primary care setting, if symptoms cannot be managed otherwise.{{Cite journal|last1=Banigo|first1=Adonye|last2=Watson|first2=David|last3=Ram|first3=Bhaskar|last4=Ah-See|first4=Kim|date=2018-05-16|title=Orofacial pain|url=https://www.bmj.com/content/361/bmj.k1517|journal=BMJ|language=en|volume=361|pages=k1517|doi=10.1136/bmj.k1517|issn=0959-8138|pmid=29769194|s2cid=21701778|url-access=subscription}}

Epidemiology

Orofacial pain is common problem. For example, in the United States, one report estimated that 22% of the general population had experienced some form of facial pain at some point in the 6-month period before questioning, of which 12% was toothache.{{cite book|veditors=Hargreaves KM, Cohen S|others=Berman LH (web editor)|title=Cohen's pathways of the pulp|year=2010|publisher=Mosby Elsevier|location=St. Louis, Mo.|isbn=978-0-323-06489-7|pages=50|edition=10th}} In the United Kingdom, 7% of the general population reported having some degree of chronic orofacial pain.{{cite journal|last=Zakrzewska|first=Joanna M|title=Multi-dimensionality of chronic pain of the oral cavity and face|journal=The Journal of Headache and Pain|year=2013|volume=14|issue=1|pages=37|doi=10.1186/1129-2377-14-37|pmid=23617409|pmc=3642003 |doi-access=free }} Other reports indicate a prevalence of 10–15% for TMD in the general population.

A systematic review looking at the prevalence of orofacial pain found that highest prevalence was for pain on opening the mouth (21%-49%), muscle tenderness (17%-97%) and self-reported joint pain (5%-31%).{{Cite journal|last1=Macfarlane|first1=T. V|last2=Glenny|first2=A-M|last3=Worthington|first3=H. V|date=2001-09-01|title=Systematic review of population-based epidemiological studies of oro-facial pain|journal=Journal of Dentistry|language=en|volume=29|issue=7|pages=451–467|doi=10.1016/S0300-5712(01)00041-0|pmid=11809323|issn=0300-5712}}

Feline orofacial pain syndrome

Feline orofacial pain syndrome is a condition in cats characterised by episodic unilateral oral pain and self-mutilation of the tongue. The aetiology is unknown but is believed to be a neuropathic inherited disorder. Common analgesics often do not work well and anti-convulsant analgesics are required to manage pain. The Burmese cat is predisposed.{{cite book | last=Bellows | first=Jan | title=Feline Dentistry | publisher=John Wiley & Sons | publication-place=Hoboken, NJ | date=2022-01-21 | isbn=978-1-119-56803-2 | page=109}}

See also

References

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