pseudo-arrhenotoky

{{Short description|Biological phenomenon}}

Pseudo-arrhenotoky or paternal genome elimination is the phenomenon where males develop from fertilized eggs but the paternal genome is heterochromatinized or lost in the somatic cells and not passed on to their offspring.

This phenomenon occurs in certain mites,{{Cite journal | last1 = Sabelis | first1 = M. W. | last2 = Nagelkerke | first2 = C. J. | doi = 10.1007/BF01196192 | title = Evolution of pseudo-arrhenotoky | journal = Experimental & Applied Acarology | volume = 4 | issue = 3 | pages = 301–318| year = 1988 | url = https://pure.uva.nl/ws/files/2144006/27922_125970y.pdf }} beetles{{Cite journal | last1 = Borsa | first1 = P. | last2 = Kjellberg | first2 = F. | doi = 10.1038/hdy.1996.20 | title = Experimental evidence for pseudo-arrhenotoky in Hypothenemus hampei (Coleoptera: Scolytidae) | journal = Heredity | volume = 76 | issue = 2 | pages = 130–135 | year = 1996 | doi-access = free }} and mealybugs{{Cite journal

| last1 = Bongiorni | first1 = S.

| last2 = Mazzuoli | first2 = M.

| last3 = Masci | first3 = S.

| last4 = Prantera | first4 = G.

| title = Facultative heterochromatization in parahaploid male mealybugs: Involvement of a heterochromatin-associated protein

| journal = Development

| volume = 128

| issue = 19

| pages = 3809–3817

| year = 2001

| doi = 10.1242/dev.128.19.3809

| pmid = 11585806

}} and scale insects.{{Cite journal

| pmid = 20460159

| year = 2010

| last1 = Andersen

| first1 = J. C.

| title = A phylogenetic analysis of armored scale insects (Hemiptera: Diaspididae), based upon nuclear, mitochondrial, and endosymbiont gene sequences

| journal = Molecular Phylogenetics and Evolution

| volume = 57

| issue = 3

| pages = 992–1003

| last2 = Wu

| first2 = J

| last3 = Gruwell

| first3 = M. E.

| last4 = Gwiazdowski

| first4 = R

| last5 = Santana

| first5 = S. E.

| last6 = Feliciano

| first6 = N. M.

| last7 = Morse

| first7 = G. E.

| last8 = Normark

| first8 = B. B.

| doi = 10.1016/j.ympev.2010.05.002

| bibcode = 2010MolPE..57..992A

}}

When the males have a diploid number of chromosomes they are termed parahaploids as the paternal genes are not expressed at all. The paternal chromosomes are inactivated by heterochromatization in all the cells at an early embryonic stage. The adult cells have one set of inactive H chromosomes and one set of euchromatin E chromosomes. These H chromosomes are eliminated from the sperm during or just before spermatogenesis. In a few other species all the cells in an adult are haploid due to elimination of the paternal chromosomes at an early developmental stage. This variant is called the diaspidid system after the scale insect clade (Diaspididae) where it was discovered.{{Cite journal | last1 = Ross | first1 = L. | last2 = Pen | first2 = I. | last3 = Shuker | first3 = D. M. | title = Genomic conflict in scale insects: The causes and consequences of bizarre genetic systems | doi = 10.1111/j.1469-185X.2010.00127.x | journal = Biological Reviews | pages = 807–28 | year = 2010 | pmid = 20233171| volume=85| issue = 4 }}{{Cite journal | last1 = Haig | first1 = D. | doi = 10.1046/j.1420-9101.1993.6010069.x | title = The evolution of unusual chromosomal systems in coccoids: Extraordinary sex ratios revisited | journal = Journal of Evolutionary Biology | volume = 6 | pages = 69–77 | year = 1993 | type=Free full text| doi-access = free }} It is also found in some mites.{{Cite journal | last1 = Nagelkerke | first1 = C. J. | last2 = Sabelis | first2 = M. W. | doi = 10.1046/j.1420-9101.1998.11060649.x | title = Precise control of sex allocation in pseudo-arrhenotokous phytoseiid mites | journal = Journal of Evolutionary Biology | volume = 11 | issue = 6 | pages = 649–684 | year = 1998 | doi-access = free }}

Genetically this system is equivalent both to haplodiploid arrhenotoky where the males are haploid and develop from unfertilized eggs and to certain cases of diploid arrhenotoky where the males get a diploid chromosome set from their mother but inactivate and fail to pass on half of them.{{Cite journal | last1 = Normark | first1 = B. B. | doi = 10.1146/annurev.ento.48.091801.112703 | title = The evolution of alternative genetic systems in insects| journal = Annual Review of Entomology | volume = 48 | pages = 397–423 | year = 2003 | pmid = 12221039}} Pseudo-arrhenotoky causes a female's genetic contribution to her son's children to double. This intragenomic conflict between maternal and paternal genes can lead to pseudo-arrhenotoky arising.{{cite journal | doi = 10.2307/2640441 | first1 = R. H. | last1 = Cruickshank | first2 = R. H. | last2 = Thomas | year = 1999 | title = Evolution of Haplodiploidy in Dermanyssine Mites (Acari: Mesostigmata) | journal = Evolution | volume = 53 | issue = 6 | pages = 1796–1803 | jstor = 2640441| pmid = 28565470 }} Under conditions where the optimal sex ratio is biased, pseudo-arrhenotoky allows the female a precise control of the ratio of sons to daughters. Pseudo arrhenotoky has evolved into haplodiploidy (haploid arrhenotoky) in some species possibly due to sustained intragenomic conflict or due to pressure to colonize habitats by a single unmated female. Relative to arrhenotoky, pseudo-arrhenotoky may have the advantage of allowing DNA damage to be repaired.