sofalcone
{{Short description|Chemical compound}}
{{cs1 config|name-list-style=vanc}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 448141641
| IUPAC_name = [5-[(3-Methylbut-2-en-1-yl)oxy]-2-((2E)-3-
| image = Sofalcone.svg
| tradename =
| Drugs.com = {{drugs.com|international|sofalcone}}
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status = Rx-only
| routes_of_administration = Oral
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 153175-87-2
| ATC_prefix = none
| ATC_suffix =
| ATC_supplemental =
| PubChem = 5282219
| ChEBI = 135732
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 2B668TJX8E
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D01956
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4445402
| C=27 | H=30 | O=6
| smiles = CC(=CCOC1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2)OCC=C(C)C)OCC(=O)O)C
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C27H30O6/c1-19(2)13-15-31-22-8-5-21(6-9-22)7-12-25(28)24-11-10-23(32-16-14-20(3)4)17-26(24)33-18-27(29)30/h5-14,17H,15-16,18H2,1-4H3,(H,29,30)/b12-7+
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = GFWRVVCDTLRWPK-KPKJPENVSA-N
}}
Sofalcone (INN) is an oral gastrointestinal medication used in Japan.{{cite web | url = https://www.drugs.com/international/sofalcone.html | title = Sofalcone | publisher = drugs.com}} It is a synthetic analog of sophoradin,{{cite journal |vauthors=Konturek SJ, Mrzozowski T, Drozdowicz D, Pawlik W, Sendur R |title=Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin |journal=Hepatogastroenterology |volume=34 |issue=4 |pages=164–70 |date=August 1987 |pmid=3478294 }} a type of natural phenol found in Sophora tonkinensis, an herb used in traditional Chinese medicine.
References
{{Reflist}}
{{Drugs for peptic ulcer and GORD}}
{{Chalconoid}}
Category:Drugs acting on the gastrointestinal system and metabolism
{{gastrointestinal-drug-stub}}