1-Aminotetralin
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| ImageFile = 1-Aminotetralin.svg
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| IUPACName = 1,2,3,4-tetrahydronaphthalen-1-amine
| OtherNames = 1-AT; 1-Amino-1,2,3,4-tetrahydronaphthalene
| Section1 = {{Chembox Identifiers
| CASNo = 2217-40-5
| CASNo_Ref = {{Cascite|correct|CAS}}
| ChemSpiderID = 17067
| EINECS = 220-973-7
| PubChem = 18066
| StdInChI=1S/C10H13N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10H,3,5,7,11H2
| StdInChIKey = JRZGPXSSNPTNMA-UHFFFAOYSA-N
| SMILES = C1CC(C2=CC=CC=C2C1)N
| UNII = O7A3GV2PNX
}}
| Section2 = {{Chembox Properties
| C=10 | H=13 | N=1
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| Section3 = {{Chembox Hazards
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1-Aminotetralin (1-AT), also known as 1-amino-1,2,3,4-tetrahydronaphthalene, is a chemical compound and one of the possible positional isomers of aminotetralin.{{cite book | last1=Trachsel | first1=D. | last2=Lehmann | first2=D. | last3=Enzensperger | first3=C. | title=Phenethylamine: von der Struktur zur Funktion | trans-title = Phenethylamines: From Structure to Function | edition = 1 | publisher=Nachtschatten-Verlag | location = Solothurn | series=Nachtschatten-Science | year=2013 | isbn=978-3-03788-700-4 | oclc = 858805226 | url=https://books.google.com/books?id=-Us1kgEACAAJ | language=de | page=263}} It consists of a tetralin core with an amino substituent on one of the carbon atoms.
Derivatives
1-Aminotetralin is the parent structure of a number of drugs, including the following:{{cite journal | last1=Shah | first1=Bhumi M. | last2=Kachhadiya | first2=Radhika N. | title=Shaping the future of medicine through diverse therapeutic applications of tetralin derivatives | journal=Medicinal Chemistry Research | volume=34 | issue=1 | date=2025 | issn=1054-2523 | doi=10.1007/s00044-024-03331-y | pages=86–113 | url=https://www.researchgate.net/publication/385559544}}
{{columns-list|colwidth=15em|
- Dasotraline
- Desmethylsertraline
- Ethonam
- Lometraline
- LP-12
- LP-44
- Sertraline
- SR 59230A
- Tametraline
- Tochergamine
}}
Tramazoline is another related compound.
See also
References
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