1952 Challenge Desgrange-Colombo

{{Short description|5th season of the tournament}}

{{ Infobox cycling season

| name = 1952 Challenge Desgrange-Colombo

| edition = 5

| competition = Challenge Desgrange-Colombo

| image =

| image_caption =

| image_alt =

| image_size =

| dates = 19 March – 26 October

| location = Europe

| rounds = 11

| individual_champion = {{flagathlete|Ferdinand Kübler|SUI}}

| individual_champion_team = Frejus

| nations_champion = {{ITA}}

| previous = 1951

| next = 1953

}}

The 1952 Challenge Desgrange-Colombo was the fifth edition of the Challenge Desgrange-Colombo. It included eleven races: all the races form the 1951 edition were retained with no additions. Ferdinand Kübler won his second edition, having previously won in 1950. Italy won the nations championship.