HLA-DR9
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align="center" colspan="2" | Image:DR Illustration.PNG | |
align="center" colspan="2" | human major histocompatibility complex, class II, DR9 | |
bgcolor="#e7dcc3" | Haplotypes groups
| bgcolor="#eeeeee" | DQA*01:DRB1*0901 to DQA*01:DRB1*0906 | |
colspan="2" bgcolor="#dddddd" | Structure (See HLA-DR) | |
style="background:#f8f8f8"
| bgcolor="#dddddd" | Identifiers | align="center" | alpha *0101 |
bgcolor="#e7dcc3" | Symbol(s)
| bgcolor="#eeeeee" | [http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=HGNC4947 HLA-DRA]{{Dead link|date=January 2020 |bot=InternetArchiveBot |fix-attempted=yes }} | |
bgcolor="#e7dcc3" | EBI-HLA
| bgcolor="#eeeeee" | [http://www.ebi.ac.uk/cgi-bin/imgt/hla/get_allele.cgi?DRA*0101 DRA*0101] | |
style="background:#f8f8f8"
| bgcolor="#dddddd" | Identifiers | align="center" | beta 1 *0901 |
bgcolor="#e7dcc3" | Symbol(s)
| bgcolor="#eeeeee" | [http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=4953 HLA-DRB1]{{Dead link|date=January 2020 |bot=InternetArchiveBot |fix-attempted=yes }} | |
bgcolor="#e7dcc3" | EBI-HLA
| bgcolor="#eeeeee" | [http://www.ebi.ac.uk/cgi-bin/imgt/hla/get_allele.cgi?DRB1*0901 DRB1*0901] {{Webarchive|url=https://web.archive.org/web/20110515174057/http://www.ebi.ac.uk/cgi-bin/imgt/hla/get_allele.cgi?DRB1*0901 |date=2011-05-15 }} | |
colspan="2" bgcolor="#dddddd" | Shared data | |
bgcolor="#e7dcc3" | Locus
| bgcolor="#eeeeee" | chr.6 [https://www.ncbi.nlm.nih.gov/Omim/getmap.cgi?chromosome=6p21.31 6p21.31] |
HLA-DR09 (DR9) is a HLA-DR serotype that recognizes the DRB1*0901 gene product.
Serology
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|+ DR9 recognition of some DRB1*0901 alleles[http://www.ebi.ac.uk/imgt/hla/allele.html derived from IMGT/HLA] | ||||
style="background:#f0f0ff"
| style="width:60px" | DRB1* | style="width:60px" | DR9
| style="width:60px" | | style="width:60px" | | style="width:60px" | Sample | |
style="background:#f0f0ff"
| allele | % | % | % | size (N) |
style = "background:#e8e8f8" | 0901 | 95 | 1058 |
The serological reaction of DR9 is relatively good. The serology of DRB1*0902 to *0906 serotypes is unknown.
Disease associations
DRB1*0901: Early childhood myasthenia gravis{{cite journal |vauthors=Shinomiya N, Nomura Y, Segawa M | title = A variant of childhood-onset myasthenia gravis: HLA typing and clinical characteristics in Japan. | journal = Clin Immunol | volume = 110 | issue = 2 | pages = 154–8 | year = 2004 | pmid = 15003812 | doi = 10.1016/j.clim.2003.10.004}}
=Extended linkage=
Genetic linkage
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|align="center" colspan="4" | DR09 Haplotypes | ||
style="background:#f8f8f8"
| bgcolor="#dddddd"| ! bgcolor="#dddddd"| DRA !! bgcolor="#dddddd"| DRB1 !! bgcolor="#dddddd" | | ||
style="background:#f8f8f8"
| rowspan = "1" bgcolor="#e7dcc3" | Haplotypes | bgcolor="#eeeeee"| *0101 | bgcolor="#eeeeee"| *0901 | bgcolor="#eeeeee" | *0101 |
style="background:#f8f8f8"
| bgcolor="#dddddd"| ! bgcolor="#dddddd"| DQA1 !! bgcolor="#dddddd"| DQB1 !! bgcolor="#dddddd" | DRB1 | ||
bgcolor="#e7dcc3" | Haplotypes
| bgcolor="#eeeeee"| *0301 | bgcolor="#eeeeee"| *0303 | bgcolor="#eeeeee" | *0901 |
style="background:#f8f8f8"
| bgcolor="#dddddd"| ! bgcolor="#dddddd"| HLA-A !! bgcolor="#dddddd"| HLA-B !! bgcolor="#dddddd" | DRB1 | ||
bgcolor="#e7dcc3" | Haplotypes
| bgcolor="#eeeeee"| *0000 | bgcolor="#eeeeee"| *0000 | bgcolor="#eeeeee" | *0901 |
HLA-DR9 is genetically linked to HLA-DR53, and HLA-DQ3 and DQ9 serotypes.