John Neoptolemos

{{Short description|British surgeon}}

{{Infobox medical person

|name = John P Neoptolemos

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|image = Neoptolemos Heidelberg 2021.jpg

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|caption = John P. Neoptolemos in 2021

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|birth_place = Pano Zodeia, Cyprus

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|profession = Surgeon

|specialism = General surgery, Oncology

|research_field = Pancreatic disease, Pancreatic cancer, Pancreatitis

|known_for = European Study Group for Pancreatic Cancer Research (ESPAC)

|years_active =

|education = Churchill College, Cambridge, University of London, UCSD, University of Paris, University of Ulm

|work_institutions = University of Birmingham (Dudley Road Hospital), (Queen Elizabeth Hospital), Liverpool University, University of Heidelberg (University Hospital Heidelberg)

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John P. Neoptolemos is a British surgeon and professor who specialised in pancreas research.{{Cite web |date=2011-01-17 |title=Apple's Steve Jobs to take medical leave |url=http://www.theguardian.com/technology/2011/jan/17/steve-jobs-apple |access-date=2022-03-11 |website=the Guardian |language=en}}{{Cite news |date=2013-01-10 |title=Manchester University deaths 'not linked to radiation' |language=en-GB |work=BBC News |url=https://www.bbc.com/news/uk-england-manchester-20975430 |access-date=2022-03-11}} His specific areas of research are diagnosis,{{Cite news |date=2001-11-10 |title=New pancreatic cancer hope |language=en-GB |url=http://news.bbc.co.uk/2/hi/health/1645596.stm |access-date=2022-03-11}} biological predictors of treatment response{{Cite news |date=2016-06-03 |title='Major win' in pancreatic cancer fight |language=en-GB |work=BBC News |url=https://www.bbc.com/news/health-36444413 |access-date=2022-03-11}}{{Cite web |date=2017-01-25 |title=Fight against pancreatic cancer takes 'monumental leap forward' |url=https://www.independent.co.uk/life-style/health-and-families/health-news/pancreatic-cancer-monumental-leap-treatment-chemotherapy-liverpool-university-a7544166.html |access-date=2022-03-11 |website=The Independent |language=en}} and therapies of pancreatic cancer{{Cite web |date=2016-06-03 |title=Drug combination may extend pancreas cancer survival, trial finds |url=http://www.theguardian.com/society/2016/jun/03/pancreas-cancer-survival-extend-drugs-combination-liverpool-university |access-date=2022-03-11 |website=the Guardian |language=en}}{{Cite web |date=2017-01-25 |title=Study establishes new standard of care for pancreatic cancer patients |url=https://news.cancerresearchuk.org/2017/01/25/study-establishes-new-standard-of-care-for-pancreatic-cancer-patients/ |access-date=2022-03-01 |website=Cancer Research UK - Cancer News |language=en}}{{Cite web |date=2017-01-25 |title=Trial finds combination of pancreatic cancer drugs extends survival |url=http://www.theguardian.com/science/2017/jan/25/pancreatic-cancer-drugs-trial-combination-extends-survival |access-date=2022-03-11 |website=the Guardian |language=en}} as well as acute, chronic, and hereditary pancreatitis. Neoptolemos was a British Department of Health Platinum Award holder from 2004.{{Cite web |title=Nominal roll of consultant awards in England and Wales: 2017 |url=https://www.gov.uk/government/publications/nominal-roll-of-consultant-awards-in-england-and-wales-2017 |access-date=2022-03-11 |website=GOV.UK |date=3 August 2018 |language=en}} He was elected a Member of the Academia Europaea in 2019.{{cite web |title=Academia Europea Members |url=https://www.ae-info.org/ae/Member/Neoptolemos_John/CV}}

Early life, education, career

Neoptolemos was born in Pano Zodhia, Cyprus and raised in London. He graduated from the University of Cambridge (Churchill College) (1970-1973), and at Guy's Hospital, London (1973-1976). Neoptolemos completed his academic and clinical training in Leicester under the tutelage of Professor Sir Peter Bell,{{Cite journal |last1=Neoptolemos |first1=John P. |last2=Heagerty |first2=A. M. |last3=Nicholson |first3=M. |last4=James |first4=R. F. L. |last5=Clayton |first5=H. |last6=Bell |first6=P. R. F. |date=1987 |title=Inadequacy Of Oleic Acid In Erythrocytes As A Marker Of Malignancies |url=https://www.jstor.org/stable/29526898 |journal=British Medical Journal (Clinical Research Edition) |volume=294 |issue=6580 |pages=1157–1158 |jstor=29526898 |issn=0267-0623}}{{Cite journal |last1=Neoptolemos |first1=John P. |last2=Lloyd |first2=David M. |last3=Carr-Locke |first3=David L. |date=1984 |title=Diagnosing Gall Bladder Disease |url=https://www.jstor.org/stable/29515843 |journal=British Medical Journal (Clinical Research Edition) |volume=289 |issue=6437 |pages=108 |doi=10.1136/bmj.289.6437.108-a |jstor=29515843 |pmid=6428671 |pmc=1441925 |issn=0267-0623}} being awarded a Doctorate in Medicine in 1986 for his thesis "Effect of surgery on monocyte function in patients with colorectal cancer".{{cite journal |last1=Neoptolemos |first1=JP |last2=Wood |first2=P |last3=Everson |first3=NW |last4=Bell |first4=PR |title=The effect of surgical procedures on monocyte function in patients with carcinoma of the colon and rectum |journal=Surgery, Gynecology & Obstetrics |date=September 1986 |volume=163 |issue=3 |pages=235–42 |pmid=3750179 }} During surgical training in Ulm he met Markus Büchler, together setting up the European Study for Pancreas Cancer Research (ESPAC){{cite journal |last1=Neoptolemos |first1=J. P. |last2=Dunn |first2=J. A. |last3=Stocken |first3=D. D. |last4=Almond |first4=J. |last5=Link |first5=K. |last6=Beger |first6=H. |last7=Bassi |first7=C. |last8=Falconi |first8=M. |last9=Pederzoli |first9=P. |last10=Dervenis |first10=C. |last11=Fernandez-Cruz |first11=L. |last12=Lacaine |first12=F. |last13=Pap |first13=A. |last14=Spooner |first14=D. |last15=Kerr |first15=D. J. |last16=Friess |first16=H. |last17=Büchler |first17=M. W. |title=Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial |journal=The Lancet |date=10 November 2001 |volume=358 |issue=9293 |pages=1576–1585 |doi=10.1016/S0140-6736(01)06651-X |pmid=11716884 |s2cid=23803289 }} later.

After appointments at the University of Birmingham, Neoptolemos was elected Chair of Surgery of Liverpool University and Head of Department of Surgery in 1996{{Cite journal |last1=West |first1=P. A. |last2=Parsons |first2=Keith |last3=Evans |first3=Susan |last4=Laurence |first4=Mike |last5=McKenzie |first5=Kwame |last6=Jakeman |first6=Nicola |last7=Gregson |first7=P. N. |last8=Stewart |first8=Andy |last9=Seddon |first9=David |last10=Smith |first10=Simon |last11=Hart |first11=Julian Tudor |date=2001 |title=Why Are Doctors So Unhappy? |journal=BMJ: British Medical Journal |volume=322 |issue=7298 |pages=1361–1365 |doi=10.1136/bmj.322.7298.1361 |jstor=25467075 |pmid=11407364 |pmc=1120436 |issn=0959-8138}}{{Cite news |last=O'Connor |first=Anahad |date=2002-07-29 |title=Bertram D. Cohn, 76, Surgeon Who Created Embolism Filter |language=en-US |work=The New York Times |url=https://www.nytimes.com/2002/07/29/nyregion/bertram-d-cohn-76-surgeon-who-created-embolism-filter.html |access-date=2022-03-11 |issn=0362-4331}} to focus on pancreas disease research together with Professor Ole Petersen for the University,{{Cite journal |last1=Raraty |first1=Michael |last2=Ward |first2=Jeremy |last3=Erdemli |first3=Gul |last4=Vaillant |first4=Camille |last5=Neoptolemos |first5=John P. |last6=Sutton |first6=Robert |last7=Petersen |first7=Ole H. |date=2000 |title=Calcium-Dependent Enzyme Activation and Vacuole Formation in the Apical Granular Region of Pancreatic Acinar Cells |journal=Proceedings of the National Academy of Sciences of the United States of America |volume=97 |issue=24 |pages=13126–13131 |doi=10.1073/pnas.97.24.13126 |jstor=123666 |pmid=11087863 |pmc=27189 |bibcode=2000PNAS...9713126R |issn=0027-8424|doi-access=free }}{{Cite journal |last1=Criddle |first1=David N. |last2=Raraty |first2=Michael G. T. |last3=Neoptolemos |first3=John P. |last4=Tepikin |first4=Alexei V. |last5=Petersen |first5=Ole H. |last6=Sutton |first6=Robert |last7=Burgen |first7=Arnold S. |date=2004 |title=Ethanol Toxicity in Pancreatic Acinar Cells: Mediation by Nonoxidative Fatty Acid Metabolites |journal=Proceedings of the National Academy of Sciences of the United States of America |volume=101 |issue=29 |pages=10738–10743 |doi=10.1073/pnas.0403431101 |jstor=3372729 |pmid=15247419 |pmc=490004 |bibcode=2004PNAS..10110738C |issn=0027-8424|doi-access=free }} and to develop the surgical services of the Royal Liverpool University Hospital.{{Cite book |last=McIntyre-Brown |first=Arabella |url=https://www.worldcat.org/oclc/318282497 |title=Liverpool : the first 1,000 years |date=2001 |publisher=Garlic Press |others=Guy Woodland |isbn=1-904099-00-9 |location=Liverpool, England |oclc=318282497}} Neoptolemos became the director of the newly established Liverpool Clinical Trial Unit (LCTU){{Cite web |date=2017-03-09 |title=Professor John Neoptolemos |url=https://www.cancerresearchuk.org/our-research/researchers/professor-john-neoptolemos |access-date=2022-03-01 |website=Cancer Research UK |language=en}} from 1996 and the chairman of the Pancreas Tumour Multi-Disciplinary Team at the Royal Liverpool University Hospital from 2001.{{Cite web |date=2017-03-09 |title=Professor John Neoptolemos |url=https://www.cancerresearchuk.org/our-research/researchers/professor-john-neoptolemos |access-date=2022-03-01 |website=Cancer Research UK |language=en}} Neoptolemos and Petersen established the National Institutes of Health Research (NIHR) Pancreas Biomedical Research Unit from 2007, renewed again in 2012.

In 2005 he became head of the new School of Cancer Studies.{{Cite news |title=Pancreatic cancer vaccine on trial |language=en-GB |work=BBC News |url=https://www.bbc.com/news/av/health-13085616 |access-date=2022-03-11}}

From 2007 he became the director of the Cancer Research UK Liverpool Cancer Trials Unit.{{Cite web |date=2017-01-25 |title=New approach could improve survival time for pancreatic cancer patients - University of Liverpool News |url=https://news.liverpool.ac.uk/2017/01/25/new-approach-improves-five-year-survival-for-pancreatic-cancer-patients/ |access-date=2022-03-01 |website=News |language=en}}

Neoptolemos was co-director of the CRUK and NIHR Liverpool Experimental Cancer Centre from 2007 until 2012 and from then the director of the LCTU GCP Labs as well as the director the CRUK from 2011 until 2013.{{Cite web |title=KEY CANCER VACCINE TRIAL BEGINS IN CITY. - Free Online Library |url=https://www.thefreelibrary.com/KEY+CANCER+VACCINE+TRIAL+BEGINS+IN+CITY-a0254109126 |access-date=2022-03-11 |website=www.thefreelibrary.com}} The Cancer Research UK Liverpool Centre received the Freedom of the City of Liverpool{{cite news |date=8 February 2012 |title=Cancer centre given Freedom of the City of Liverpool |agency=BBC |url=https://www.bbc.com/news/uk-england-merseyside-16956524}}{{cite web |date=13 February 2012 |title=Cancer Research UK Centre receives Freedom of the City |url=https://news.liverpool.ac.uk/2012/02/13/cancer-research-uk-centre-receives-freedom-of-the-city/ |access-date=13 December 2021 |website=University of Liverpool News}} on 8 February 2012.

In 2014 the LCTU Cancer Research UK Liverpool Cancer Trials Unit received accreditation as National Cancer Research Institute (NCRI) Cancer Trials Unit. The associated Pancreas Unit became the Health Services Journal National Award Winner in 2013.{{Cite web |last=2013-11-19T23:00:00+00:00 |title=HSJ Awards 2013 winners announced |url=https://www.hsj.co.uk/home/hsj-awards-2013-winners-announced/5065465.article |access-date=2022-01-27 |website=Health Service Journal |language=en}}

= National and international scientific role =

Neoptolemos was the Clinical Chair for the NICE Guidelines on Pancreatic Cancer (2015-2017).{{Cite web |date=2015-12-02 |title=Professor appointed national Clinical Chair for Pancreatic Cancer - University of Liverpool News |url=https://news.liverpool.ac.uk/2015/12/02/professor-appointed-national-clinical-chair-for-pancreatic-cancer/ |access-date=2022-01-27 |website=News |language=en}} John Neoptolemos has been Secretary and President of the European Pancreas Club (EPC),{{cite news |title=Professor elected President of the European Pancreatic Club |url=https://news.liverpool.ac.uk/2016/06/27/professor-elected-president-european-pancreatic-club/ |access-date=13 December 2021 |publisher=University of Liverpool |date=17 June 2016}} as well as President of the Pancreatic Society of Great Britain and Ireland{{cite web |title=PSGBI Committee |url=https://www.psgbi.org/society/committee/ |website=Pancreatic Society of Great Britain and Ireland |access-date=13 December 2021}} and the International Association of Pancreatology{{cite web |title=IAP Presidents |url=https://internationalpancreatology.org/presidents/ |website=International Association of Pancreatology |access-date=13 December 2021}} (IAP).{{Cite journal|last1=Goebell|first1=Harald|last2=Ammann|first2=Rudolf|last3=Creutzfeldt|first3=Werner|date=May 2005|title=History of the European Pancreatic Club: The First 40 Years 1965-2005|url=https://linkinghub.elsevier.com/retrieve/pii/S1424390305800808|journal=Pancreatology|language=en|volume=5|issue=1|pages=1–15|doi=10.1159/000086210|pmid=15942268|s2cid=44551677}} As IAP President he developed the first IAP Guidelines in 2003 – on acute pancreatitis.{{Cite journal|last1=Uhl|first1=Waldemar|last2=Warshaw|first2=Andrew|last3=Imrie|first3=Clement|last4=Bassi|first4=Claudio|last5=McKay|first5=Colin J.|last6=Lankisch|first6=Paul G.|last7=Carter|first7=Ross|last8=Magno|first8=Eugene Di|last9=Banks|first9=Peter A.|last10=Whitcomb|first10=David C.|last11=Dervenis|first11=Christos|date=January 2002|title=IAP Guidelines for the surgical management of acute pancreatitis|url=https://linkinghub.elsevier.com/retrieve/pii/S1424390302800552|journal=Pancreatology|language=en|volume=2|issue=6|pages=565–573|doi=10.1159/000067684|pmid=12435871}}

Neoptolemos received international recognition including the Lifetime Achievement Award of the EPC{{cite news |title=Professor John Neoptolemos receives lifetime achievement award |url=https://www.liverpool.ac.uk/life-sciences/news/articles/professor-john-neoptolemos-receives-lifetime-achievement-award |access-date=13 December 2021 |publisher=University of Liverpool School of Life Sciences |date=16 July 2013}} (2013); the Ruth Brufsky Award for Pancreas Cancer Research{{cite web |title=PancreasFest 2017 |url=https://pancreasfest.com/wp-content/uploads/2017/04/PF17-Schedule-18April17-dcw.pdf |publisher=Division of Gastroenterology, Hepatology and Nutrition University of Pittsburgh |access-date=13 December 2021}} (2017); and the Henry Lynch Award for Inherited Pancreas Diseases{{cite web |title=European Pancreas Club Jubilee Meeting 2018 |url=http://www2.medizin.uni-greifswald.de/gastro/fileadmin/user_upload/Dokumente/Programm_EPC_2018.pdf |access-date=13 December 2021}} (2018).

Scientific merits

In 1989 Neoptolemos was the founder of the European Study for Pancreas Cancer Research (ESPAC){{Cite news |title=Mix of pancreatic cancer drugs extends survival, study shows |url=https://www.irishtimes.com/life-and-style/health-family/mix-of-pancreatic-cancer-drugs-extends-survival-study-shows-1.2950528 |access-date=2022-03-11 |newspaper=The Irish Times |language=en}}{{Cite web |last=Ärzteblatt |first=Deutscher Ärzteverlag GmbH, Redaktion Deutsches |date=2017-01-26 |title=Pankreaskarzinom: Capecitabin plus Gemcitabin verlängern Überleben |url=https://www.aerzteblatt.de/nachrichten/72697/Pankreaskarzinom-Capecitabin-plus-Gemcitabin-verlaengern-Ueberleben |access-date=2022-03-01 |website=Deutsches Aerzteblatt |language=de}} that has led the way for internationally collaborative pancreas cancer trials (ESPAC 1-4 trials{{cite journal |last1=Neoptolemos |first1=John P. |last2=Stocken |first2=Deborah D. |last3=Bassi |first3=Claudio |last4=Ghaneh |first4=Paula |last5=Cunningham |first5=David |last6=Goldstein |first6=David |last7=Padbury |first7=Robert |last8=Moore |first8=Malcolm J. |last9=Gallinger |first9=Steven |last10=Mariette |first10=Christophe |last11=Wente |first11=Moritz N. |last12=Izbicki |first12=Jakob R. |last13=Friess |first13=Helmut |last14=Lerch |first14=Markus M. |last15=Dervenis |first15=Christos |last16=Oláh |first16=Attila |last17=Butturini |first17=Giovanni |last18=Doi |first18=Ryuichiro |last19=Lind |first19=Pehr A. |last20=Smith |first20=David |last21=Valle |first21=Juan W. |last22=Palmer |first22=Daniel H. |last23=Buckels |first23=John A. |last24=Thompson |first24=Joyce |last25=McKay |first25=Colin J. |last26=Rawcliffe |first26=Charlotte L. |last27=Büchler |first27=Markus W. |last28=European Study Group for Pancreatic Cancer |first28=for the |title=Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection: A Randomized Controlled Trial |journal=JAMA |date=8 September 2010 |volume=304 |issue=10 |pages=1073–1081 |doi=10.1001/jama.2010.1275 |pmid=20823433 }}{{cite journal |last1=Neoptolemos |first1=John P. |last2=Moore |first2=Malcolm J. |last3=Cox |first3=Trevor F. |last4=Valle |first4=Juan W. |last5=Palmer |first5=Daniel H. |last6=McDonald |first6=Alexander C. |last7=Carter |first7=Ross |last8=Tebbutt |first8=Niall C. |last9=Dervenis |first9=Christos |last10=Smith |first10=David |last11=Glimelius |first11=Bengt |last12=Charnley |first12=Richard M. |last13=Lacaine |first13=François |last14=Scarfe |first14=Andrew G. |last15=Middleton |first15=Mark R. |last16=Anthoney |first16=Alan |last17=Ghaneh |first17=Paula |last18=Halloran |first18=Christopher M. |last19=Lerch |first19=Markus M. |last20=Oláh |first20=Attila |last21=Rawcliffe |first21=Charlotte L. |last22=Verbeke |first22=Caroline S. |last23=Campbell |first23=Fiona |last24=Büchler |first24=Markus W. |last25=European Study Group for Pancreatic Cancer |first25=for the |title=Effect of Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid or Gemcitabine vs Observation on Survival in Patients With Resected Periampullary Adenocarcinoma: The ESPAC-3 Periampullary Cancer Randomized Trial |journal=JAMA |date=11 July 2012 |volume=308 |issue=2 |pages=147–156 |doi=10.1001/jama.2012.7352 |pmid=22782416 }}{{cite journal |last1=Neoptolemos |first1=John P |last2=Palmer |first2=Daniel H |last3=Ghaneh |first3=Paula |last4=Psarelli |first4=Eftychia E |last5=Valle |first5=Juan W |last6=Halloran |first6=Christopher M |last7=Faluyi |first7=Olusola |last8=O'Reilly |first8=Derek A |last9=Cunningham |first9=David |last10=Wadsley |first10=Jonathan |last11=Darby |first11=Suzanne |last12=Meyer |first12=Tim |last13=Gillmore |first13=Roopinder |last14=Anthoney |first14=Alan |last15=Lind |first15=Pehr |last16=Glimelius |first16=Bengt |last17=Falk |first17=Stephen |last18=Izbicki |first18=Jakob R |last19=Middleton |first19=Gary William |last20=Cummins |first20=Sebastian |last21=Ross |first21=Paul J |last22=Wasan |first22=Harpreet |last23=McDonald |first23=Alec |last24=Crosby |first24=Tom |last25=Ma |first25=Yuk Ting |last26=Patel |first26=Kinnari |last27=Sherriff |first27=David |last28=Soomal |first28=Rubin |last29=Borg |first29=David |last30=Sothi |first30=Sharmila |last31=Hammel |first31=Pascal |last32=Hackert |first32=Thilo |last33=Jackson |first33=Richard |last34=Büchler |first34=Markus W |title=Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial |journal=The Lancet |date=March 2017 |volume=389 |issue=10073 |pages=1011–1024 |doi=10.1016/S0140-6736(16)32409-6 |pmid=28129987 |s2cid=4551532 |doi-access=free }}). The ESPAC-1 trial was the first trial to establish the benefit of adjuvant treatment in pancreatic cancer favoring chemotherapy{{cite journal |last1=Neoptolemos |first1=John P. |last2=Stocken |first2=Deborah D. |last3=Friess |first3=Helmut |last4=Bassi |first4=Claudio |last5=Dunn |first5=Janet A. |last6=Hickey |first6=Helen |last7=Beger |first7=Hans |last8=Fernandez-Cruz |first8=Laureano |last9=Dervenis |first9=Christos |last10=Lacaine |first10=François |last11=Falconi |first11=Massimo |last12=Pederzoli |first12=Paolo |last13=Pap |first13=Akos |last14=Spooner |first14=David |last15=Kerr |first15=David J. |date=18 March 2004 |title=A Randomized Trial of Chemoradiotherapy and Chemotherapy after Resection of Pancreatic Cancer |journal=New England Journal of Medicine |volume=350 |issue=12 |pages=1200–1210 |doi=10.1056/NEJMoa032295 |pmid=15028824 |last16=Büchler |first16=Markus W.|doi-access=free }} rather than chemoradiotherapy.{{Cite journal |last=Gottlieb |first=Scott |date=2004 |title=Resectable pancreatic cancer needs surgery, then chemotherapy |journal=BMJ: British Medical Journal |volume=328 |issue=7441 |pages=661 |doi=10.1136/bmj.328.7441.661-a |jstor=41707160 |pmc=381249 |issn=0959-8138}}{{Cite web |title=John P. Neoptolemos, MD, PhD, on Pancreatic Ductal Adenocarcinoma: Results of the ESPAC-4 Trial - The ASCO Post |url=https://ascopost.com/archive/meetings/2016-asco-annual-meeting/john-p-neoptolemos-md-phd-on-pancreatic-ductal-adenocarcinoma-results-of-the-espac-4-trial/ |access-date=2022-03-01 |website=ascopost.com}} In 1997 he established the European Registry of Hereditary Pancreatitis and Pancreatic Cancer (EUROPAC){{cite journal |last1=Finch |first1=Margaret D. |last2=Howes |first2=Nathan |last3=Ellis |first3=Ian |last4=Mountford |first4=Roger |last5=Sutton |first5=Robert |last6=Raraty |first6=Michael |last7=Neoptolemos |first7=John P. |title=Hereditary Pancreatitis and Familial Pancreatic Cancer |journal=Digestion |date=1997 |volume=58 |issue=6 |pages=564–569 |doi=10.1159/000201502 |pmid=9438603 }}{{Cite journal |last1=Gong |first1=Yuanfeng |last2=Zhou |first2=Quanbo |last3=Zhou |first3=Yu |last4=Lin |first4=Qing |last5=Zeng |first5=Bing |last6=Chen |first6=Rufu |last7=Li |first7=Zhihua |date=2012 |title=Gastrectomy and risk of pancreatic cancer: systematic review and meta-analysis of observational studies |url=https://www.jstor.org/stable/23255042 |journal=Cancer Causes & Control |volume=23 |issue=8 |pages=1279–1288 |doi=10.1007/s10552-012-0005-z |jstor=23255042 |pmid=22674223 |s2cid=18572084 |issn=0957-5243}} for the study of genetic pancreatic diseases. In 2005 Neoptolemos co-founded the International Study Group for Pancreas Surgery (ISGPS) with Markus Büchler (Ulm) and others.{{cite journal |last1=Bassi |first1=Claudio |last2=Dervenis |first2=Christos |last3=Butturini |first3=Giovanni |last4=Fingerhut |first4=Abe |last5=Yeo |first5=Charles |last6=Izbicki |first6=Jakob |last7=Neoptolemos |first7=John |last8=Sarr |first8=Michael |last9=Traverso |first9=William |last10=Buchler |first10=Marcus |title=Postoperative pancreatic fistula: An international study group (ISGPF) definition |journal=Surgery |date=July 2005 |volume=138 |issue=1 |pages=8–13 |doi=10.1016/j.surg.2005.05.001 |pmid=16003309 }}

Awards and honors (selection)

  • The Lord Smith Medal, Pancreatic Society of Great Britain and Ireland 1987{{Cite web |title=The Lord Smith Medal {{!}} Pancreatic Society of Great Britain and Ireland |url=https://www.psgbi.org/society/the-lord-smith-medal/ |access-date=2023-10-18 |website=www.psgbi.org}}
  • Honorary Fellow of the German Society of Surgery 2012{{Cite web |title=Ehrenmitglieder |url=https://www.dgch.de/index.php?id=85&L=94 |access-date=2023-10-18 |website=www.dgch.de}}
  • Freedom of the City of Liverpool as Director Cancer Research UK Liverpool Centre 2012
  • Lifetime Achievement Award, European Pancreatic Club 2013
  • Ruth Brufsky Award for Pancreas Cancer Research 2017
  • Henry Lynch Award for Inherited Pancreas Diseases 2018
  • Member of the Academia Europaea 2019

Books (selection)

  1. Neoptolemos JP (Ed). Cancer of the Pancreas.Clinical Gastroenterology, London, Baillière Tindall, Vol 4, No 4 1990{{Cite journal |last=Kingsnorth |first=A |date=2005-12-06 |title=Baillière's clinical gastroenterology: Cancer of the pancreas. J. P. Neoptolemos, ed. 229 × 152 mm. Illustrated. 1990. London: Baillière Tindall, £27.50 |url=https://academic.oup.com/bjs/article/78/7/892/6174982 |journal=British Journal of Surgery |language=en |volume=78 |issue=7 |pages=892 |doi=10.1002/bjs.1800780747 |issn=0007-1323}}
  2. Lemoine N, Cooke T, Neoptolemos JP (Eds). Cancer: A Molecular Approach. Oxford, Blackwell Scientific, 1993 (pp 383){{Cite book |url=https://www.worldcat.org/oclc/27727126 |title=Cancer : a molecular approach |date=1994 |publisher=Blackwell Scientific Publications |others=Nicholas R. Lemoine, John Neoptolemos, T. Cooke |isbn=0-632-03511-0 |location=Oxford |oclc=27727126}}
  3. Neoptolemos JP, Lemoine N (Eds). Pancreatic Cancer: Molecular & Clinical Advances. Oxford, Blackwell Scientific 1996{{Cite journal |last=Schein |first=M |date=2005-12-06 |title=Pancreatic cancer. Molecular and clinical advances. J. P. Neoptolemos and N. R. Lemoine (eds). 250 × 775 mm. Pp. 346. Illustrated. 1995. Oxford: Blackwell Science. £59.50 |journal=British Journal of Surgery |language=en |volume=83 |issue=6 |pages=876 |doi=10.1002/bjs.1800830657 |issn=0007-1323|doi-access=free }}
  4. Beger HG, Warshaw A, Carr-Locke DL, Russell RCG, Buchler M, Neoptolemos JP, Saar M. (Eds). The Pancreas (Two Volumes). Boston, Blackwell Scientific 1998 (pp 1644){{Cite book|url=https://www.worldcat.org/oclc/36352744|title=The pancreas|date=1998|publisher=Blackwell Science|others=H. G. Beger|isbn=0-86542-420-9|location=Oxford|oclc=36352744}}
  5. Neoptolemos JP (Ed.). Acute Pancreatitis. Clinical Gastroenterology, London, Bailière Tindall 1999; Vol. 13, No. 2 (pp 152){{Cite book|last=Neoptolemos|first=John P|title=Acute Pancreatitis, Bailliere's best practice & research. Clinical gastroenterology|publisher=Bailliere Tindall|year=1999|location=London|pages=152|language=English}}
  6. Gress TM, Neoptolemos JP, Lemoine NR, Real FX (Eds). Exocrine pancreas cancer. The European Pancreatic Cancer-Research Cooperative (PC-RC). Felsenstein CCCP, Hannover. 2005 (pp 531){{Cite book|url=https://www.worldcat.org/oclc/181519963|title=Exocrine pancreas cancer the European Pancreatic Cancer-Research Cooperative (EPC-RC)|date=2005|others=Thomas Mathias Gress|isbn=978-3-00-016372-2|location=Hannover|oclc=181519963}}
  7. Neoptolemos JP and Bhutani MS. Fast Facts. Pancreas and Biliary Tree. Health Press Abingdon. 2006 (pp127){{Cite book|last=Neoptolemos|first=John P.|url=https://www.worldcat.org/oclc/746746637|title=Diseases of the pancreas and biliary tract|date=2006|publisher=Health Press|others=Manoop S. Bhutani|isbn=978-1-905832-22-4|location=Abingdon|oclc=746746637}}
  8. Neoptolemos JP and Ghaneh P (Eds). Cancer of the Pancreas. Best Practice & Research in Clinical Gastroenterology. London, Baillière Tindall{{Cite web |title=Best Practice & Research Clinical Gastroenterology {{!}} Pancreatic Cancer {{!}} ScienceDirect.com by Elsevier |url=https://www.sciencedirect.com/journal/best-practice-and-research-clinical-gastroenterology/vol/20/issue/2 |access-date=2023-10-18 |website=www.sciencedirect.com |language=en-us}}
  9. Beger HG, Warshaw A, Büchler M, Kozarek R, Lerch M, Neoptolemos JP, Shiratori K, Whitcomb D. (Eds). The Pancreas, Second Edition. Blackwell Publishing, Massachusetts, US, 2008 (pp 1006){{Cite book|url=https://www.worldcat.org/oclc/352835994|title=The pancreas : an integrated textbook of basic science, medicine, and surgery|date=2008|publisher=Blackwell Pub|others=H. G. Beger|isbn=978-1-4443-0012-3|edition=2|location=Malden, Mass.|oclc=352835994}}
  10. Neoptolemos JP, Urrutia R, Abbruzzese JL, Büchler MW (Eds). Pancreatic Cancer. Springer, New York, 2010. Two Volumes (pp1335){{Cite book|url=https://www.worldcat.org/oclc/1031374838|title=Pancreatic cancer|date=2018|others=John Neoptolemos, Raul Urrutia, James L. Abbruzzese, Markus Büchler|isbn=978-1-4939-7193-0|edition=1|location=New York, NY|oclc=1031374838}}
  11. HG Beger HG, Nakao A, Neoptolemos JP, Peng SY, Sarr MG (Eds). Pancreatic Cancer, Cystic Neoplasms and Endocrine Tumors: Diagnosis and Management.Wiley Blackwell Publishers. 2018 (pp 436){{Cite book|url=https://www.worldcat.org/oclc/898433581|title=Pancreatic cancer, cystic neoplasms and endocrine tumors : diagnosis and management|date=2016|others=H. G. Beger, Akimasa Nakao, John Neoptolemos, Shu You Peng, Michael G. Sarr|isbn=978-1-118-30783-0|location=Chichester, West Sussex|oclc=898433581}}
  12. Beger HG, Warshaw A, Hruban R, Büchler M, Lerch M, Neoptolemos JP, Tooru Shimosegawa, Whitcomb D. (Eds). The Pancreas, Third Edition. Blackwell Publishing, Massachusetts, US, 2018 (pp 1173){{Cite book |url=https://www.worldcat.org/oclc/1065547789 |title=The pancreas : an integrated textbook of basic science, medicine, and surgery |publisher=Wiley |others=H. G. Beger |year=2018 |isbn=978-1-119-18841-4 |edition=3 |oclc=1065547789}}
  13. Neoptolemos JP, Urrutia R, Abbruzzese JL, Büchler MW (Eds). Pancreatic Cancer. Springer, New York. Second Edition. 2018. Three Volumes (pp 1642){{Cite book|url=https://www.worldcat.org/oclc/1031374838|title=Pancreatic cancer|date=2018|others=John Neoptolemos, Raul Urrutia, James L. Abbruzzese, Markus Büchler|isbn=978-1-4939-7193-0|edition=2|location=New York, NY|oclc=1031374838}}
  14. Beger HG, Warshaw A, Hruban R, Büchler M, Lerch M, Neoptolemos JP, Tooru Shimosegawa, Whitcomb D. (Eds). The Pancreas, Third Edition. The Pancreas: An Integrated Textbook of Basic Science. Chinese Edition. John Wiley & Sons Limited Chichester, West Sussex, United Kingdom. PO19 8SQ. ISBN 978-1-119-18839-1. 2019

References