MDMB-5'Br-BUTINACA

{{Short description|Chemical compound}}

{{Infobox drug

| IUPAC_name = methyl (2S)-2-[(5-bromo-1-butylindazole-3-carbonyl)amino]-3,3-dimethylbutanoate

| image = MDMB-5'Br-BUTINACA_structure.png

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| width = 200px

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| CAS_number = 1185888-28-1

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| PubChem = 168325141

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| smiles = CCCCN1C2=C(C=C(C=C2)Br)C(=N1)C(=O)N[C@H](C(=O)OC)C(C)(C)C

| C=19 | H=26 | Br=1 | N=3 | O=3

| StdInChI = 1S/C19H26BrN3O3/c1-6-7-10-23-14-9-8-12(20)11-13(14)15(22-23)17(24)21-16(18(25)26-5)19(2,3)4/h8-9,11,16H,6-7,10H2,1-5H3,(H,21,24)/t16-/m1/s1

| StdInChIKey = NKCFVJNTALOWGJ-MRXNPFEDSA-N

}}

MDMB-5'Br-BUTINACA (5'-Br-MDMB-BUTINACA) is an indazole-3-carboxamide based synthetic cannabinoid receptor agonist that has been sold as a designer drug. It was first identified in Russia in August 2022. It is believed to be synthesized from the "half finished" synthesis precursor MDMB-5Br-INACA, which is shipped to the destination and then the final synthetic step is completed on arrival.[https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1159142/Cumyl-pegalone_and_other_uncontrolled_SCRA_report-FINAL.pdf Cumyl-PeGaClone and other recently encountered synthetic cannabinoid receptor agonists. A review of the evidence on their use and harms. Advisory Council on the Misuse of Drugs, 2022]{{cite journal | vauthors = Yurchenko L, Pavlovets Y |title=Recent trends in the identification of psychoactive substances. | date = August 2022 | language = Russian |journal=Latest Trends in the Field of Identification of Psychoactive Substances |volume=32 |doi=10.13140/RG.2.2.34906.62402 | url = https://www.researchgate.net/publication/363137423 }}{{cite journal | vauthors = Deventer MH, Persson M, Norman C, Liu H, Connolly MJ, Daéid NN, McKenzie C, Gréen H, Stove CP | title = In vitro cannabinoid activity profiling of generic ban-evading brominated synthetic cannabinoid receptor agonists and their analogs | journal = Drug Testing and Analysis | volume = | issue = | pages = | date = October 2023 | pmid = 37903509 | doi = 10.1002/dta.3592 | s2cid = 264671035 }}