Marie Maynard Daly

{{short description|American biochemist}}

{{Infobox scientist

| name = Marie Maynard Daly

| image = Marie Maynard Daly.jpg

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| birth_date = {{Birth date|1921|04|16}}

| birth_place = Corona, Queens, New York City, U.S.

| death_date = {{Death date and age|2003|10|28|1921|04|16}}

| death_place = New York City, U.S.

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| other_names = Marie Maynard Daly Clark

| fields = Biochemistry

| workplaces = {{Plainlist|

| education = {{Plainlist|

| thesis_title = A Study of the Products Formed by the Action of Pancreatic Amylase on Corn Starch

| thesis_url = http://catalog.hathitrust.org/Record/006098210

| thesis_year = 1947

| doctoral_advisor = Mary Letitia Caldwell

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| notable_students =

| known_for = histones, protein synthesis, cholesterol, hypertension

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| spouse = Vincent Clark{{cite web |title=Clark, Marie Maynard Daly (1921–2003) |url=https://blackpast.org/aah/clark-marie-maynard-daly-1921-2003 |website=BlackPast.org |date=7 March 2007 |access-date=7 November 2018}}

| children =

}}

Marie Maynard Daly (April 16, 1921{{snd}}October 28, 2003) was an American biochemist. She was the first African-American to receive a Ph.D. from Columbia University and the first African-American woman in the United States to earn a Ph.D. in chemistry. Daly made important contributions in four areas of research: the chemistry of histones, protein synthesis, the relationships between cholesterol and hypertension, and creatine's uptake by muscle cells.

Education

Daly attended Hunter College High School, a laboratory high school for girls run by Hunter College faculty,{{Cite book|title=African American women mists 911|last=Brown|first=Jeannette E.|date=2012|publisher=Oxford University Press|isbn=978-0199742882|location=New York|oclc=761692608}} where she was also encouraged to pursue chemistry. She then enrolled in Queens College, a small, fairly new school in Flushing, New York. She lived at home to save money and graduated magna cum laude from Queens College with her bachelor's degree in chemistry in 1942. Upon graduation, she was named a Queens College Scholar,{{cite web|title=Dr. Marie Maynard Daly: The First African-American PhD. in Chemistry|url=http://ontheshoulders1.com/2018/01/dr-marie-maynard-daly-first-african-american-phd-chemistry/|website=On the Shoulders of Giants|date=January 5, 2018|access-date=21 March 2018|archive-url=https://web.archive.org/web/20181107185255/http://ontheshoulders1.com/2018/01/dr-marie-maynard-daly-first-african-american-phd-chemistry/|archive-date=7 November 2018|url-status=dead}} an honor that is awarded to the top 2.5% of the graduating class.

Labor shortages and the need for scientists to support the war effort enabled Daly to garner fellowships to study at New York University and Columbia University for her master's and Ph.D. degrees, respectively.

Daly worked as a laboratory assistant at Queens College while studying at New York University for her master's degree in chemistry, which she completed in 1943. She became a chemistry tutor at Queens College and enrolled in the doctoral program at Columbia University, where she was supervised by Mary Letitia Caldwell, for a Ph.D. thesis titled, "A Study of the Products Formed By the Action of Pancreatic Amylase on Corn Starch" and received her Ph.D. in chemistry in 1947.{{cite web|last1=Brown|first1=Mitchell C.|title=Marie Maynard Daly: Biochemist|url=https://webfiles.uci.edu/mcbrown/display/daly.html|website=The Faces of Science: African-Americans in the Sciences|date=1996|access-date=2018-03-21|archive-url=https://web.archive.org/web/20061023225525/http://webfiles.uci.edu/mcbrown/display/daly.html|archive-date=2006-10-23|url-status=dead}}

Career

Daly worked as a physical science instructor at Howard University, from 1947 to 1948 while simultaneously conducting research under the direction of Herman Branson. After being awarded an American Cancer Society grant to support her postdoctoral research, she joined Alfred E. Mirsky's group at the Rockefeller Institute, which studied the cell nucleus and its constituents. This was the start of a seven-year research program at the Rockefeller Institute of Medicine, where Daly examined how proteins are constructed in the body. At the time, the structure and function of DNA were not yet understood.{{cite web |last1=DeBakcsy |first1=Dale |title=Marie Maynard Daly (1921–2003), America's First Black Woman Chemist |url=https://womenyoushouldknow.net/marie-maynard-daly-first-black-woman-chemist/ |website=Women You Should Know |access-date=8 November 2018|date=February 28, 2018}}

Daly began working in the College of Physicians and Surgeons at Columbia University in 1955. In collaboration with Quentin B. Deming, she studied arterial metabolism.

She continued this work as an assistant professor of biochemistry and of medicine at the Albert Einstein College of Medicine at Yeshiva University, where she and Deming moved in 1960.

From 1958 to 1963, she also served as an investigator for the American Heart Association.{{cite book |last1=Spangenburg |first1=Ray |last2=Moser |first2=Kit |title=African Americans in science, math, and invention |date=2003 |publisher=Facts on File, Inc. |location=New York |pages=55–56 |url=https://books.google.com/books?id=XSOZ8kF5ynEC |access-date=8 November 2018|isbn=9781438107745 }}

During her final years at Albert Einstein College, per Daly's efforts to increase minority enrollment in professional and graduate schools, she helped run the Martin Luther King -Robert F. Kennedy program to help prepare black students for admission.{{Cite web |date=2019-03-07 |title=Black History Month - Marie Daly |url=https://researchersgateway.com/black-history-month-marie-daly/ |access-date=2022-04-23 |website=The Researcher's Gateway |language=en-US}} In 1971 she was promoted to associate professor.

In 1975, Daly was one of 30 minority women scientists to attend a conference examining the challenges facing minority women in STEM fields. The conference was held by the American Association for the Advancement of Science. This resulted in the publication of the report, The Double Bind: The Price of Being a Minority Woman in Science (1976) which made recommendations for recruiting and retaining minority women scientists.{{cite web |last1=Collins |first1=Sibrina Nichelle |title=Unsung: Marie Maynard Daly |url=https://undark.org/article/unsung-marie-maynard-daly-women-stem/ |website=UnDark |access-date=7 November 2018|date= August 7, 2017}}{{cite book |last1=Malcom |first1=Shirley Mahaley |first2= Paula |last2= Quick Hall|first3= Janet Welsh |last3=Brown|title=The Double Bind: The Price of Being a Minority Woman in Science. Report of a Conference of Minority Women Scientists, Arlie House, Warrenton, Virginia |date=1976 |publisher=Arlie House |location=Warrenton, Virginia|page=63 |url=https://files.eric.ed.gov/fulltext/ED130851.pdf |access-date=7 November 2018}}

Daly was a member of the board of governors of the New York Academy of Sciences for two years.{{Cite web|last=|first=|date=|title=#IAmNYAS Historical Edition: Marie Maynard Daly|url=https://www.nyas.org/history-highlights/contents/editorial/iamnyas-historical-edition-marie-maynard-daly/|access-date=February 11, 2021|website=The New York Academy of Sciences}} She was a fellow of the American Association for the Advancement of Science and of the American Cancer Society. Daly was designated as a career scientist by the Health Research Council of the City of New York.

Daly retired in 1986 from the Albert Einstein College of Medicine, and in 1988 established a scholarship for African American chemistry and physics majors at Queens College in memory of her father.{{cite web|title=Ivan C. and Helen H. Daly Scholarship Endowment|url=https://qc-cuny.academicworks.com/opportunities/5176|access-date=7 September 2020}} In 1999, she was recognized by the National Technical Association as one of the top 50 women in Science, Engineering and Technology.{{cite news|last1=Irwin|first1=Demetria|title=[Unsung Sheroes] Dr. Marie Maynard Daly, a Trailblazer in Medical Research|url=http://www.ebony.com/black-history/marie-maynard-daly-ebonywhm#axzz4MdFJbNYu|access-date=21 March 2018|work=Ebony|date=March 7, 2016}}

Research

=Histones=

Daly was particularly interested in nuclear proteins. She developed methods for the fractionation of nuclear material and the determination of its composition. It was essential to separate cellular material into all of its components, without destroying or losing any of them.{{cite book |last1=Brachet |first1=Jean |url=https://books.google.com/books?id=RDmaBQAAQBAJ&pg=PA196 |title=The Cell: Biochemistry, Physiology, Morphology |last2=Mirsky |first2=Alfred E. |date=1959 |publisher=Academic Press |isbn=9781483216546 |location=New York |pages=196, 230, 257 |access-date=8 November 2018}}

She studied histones, proteins found in cell nuclei, and was able to show the amino acid composition of various histone fractions. Her studies of histones with Mirsky provided evidence for lysine-rich histones, in contrast to the arginine-rich histones described by Albrecht Kossel.{{cite book |last1=Brusch |first1=Harris |title=Histones and other nuclear proteins. |date=1965 |publisher=Academic Press |isbn=9780123955937 |pages=13–15, 76–77 |url=https://books.google.com/books?id=7pD4kdtQiMIC&pg=PA13 |access-date=8 November 2018}}{{cite journal |last1=Daly |first1=MM |last2=Mirsky|first2=AE |title=Histones with high lysine content. |journal=The Journal of General Physiology |date=20 January 1955 |volume=38 |issue=3 |pages=405–13 |pmid=13221780 |pmc=2147486 |doi=10.1085/jgp.38.3.405 }}{{cite journal |last1=Daly |first1=MM |last2=Allfrey |first2=VG |last3=Mirsky |first3=AE |title=Uptake of glycine-N15 by components of cell nuclei. |journal=The Journal of General Physiology |date=November 1952 |volume=36 |issue=2 |pages=173–9 |pmid=13011275 |pmc=2147362 |doi=10.1085/jgp.36.2.173 }}{{cite journal |last1=Daly |first1=MM |last2=Mirsky |first2=AE |last3=Ris |first3=H |title=The amino acid composition and some properties of histones. |journal=The Journal of General Physiology |date=20 March 1951 |volume=34 |issue=4 |pages=439–50 |pmid=14824510 |pmc=2147226 |doi=10.1085/jgp.34.4.439 }}

Histones have since been shown to be important in gene expression.

Daly's work on histones is now considered fundamental.{{cite web |title=Marie M. Daly PhD Memorial Lecture |url=https://einstein.yu.edu/education/phd/current-students/Marie-Daly-Lecture.aspx |website=Albert Einstein College of Medicine |access-date=7 November 2018}}

=Proteins and nucleic acids=

Daly developed methods for separating out the nuclei of tissues and measuring the base composition of purines and pyrimidines in desoxypentose nucleic acids. She concluded, among other things, that "no bases other than adenine, guanine, thymine, and cytosine were present in appreciable amounts."{{cite journal |last1=Daly |first1=M. M. |title=Purine and Pyrimidine Contents of Some Desoxypentose Nucleic Acids |journal=The Journal of General Physiology |date=20 May 1950 |volume=33 |issue=5 |pages=497–510 |doi=10.1085/jgp.33.5.497 |pmid=15422104 |pmc=2147206 }}

She investigated protein synthesis, including the role of cytoplasmic ribonucleoprotein in protein synthesis.{{cite journal |last1=Allfrey |first1=VG |last2=Daly |first2=MM |last3=Mirsky |first3=AE |title=Some observations on protein metabolism in chromosomes of non-dividing cells. |journal=The Journal of General Physiology |date=20 January 1955 |volume=38 |issue=3 |pages=415–24 |pmid=13221781 |pmc=2147482 |doi=10.1085/jgp.38.3.415 }} Using radiolabeled amino acid glycine, she was able to measure how protein metabolism changed under feeding and fasting conditions in mice. This allowed her to monitor the activity of the cytoplasm as the radiolabeled glycine was taken up into the cell nucleus.

In 1953, Watson and Crick described the structure of DNA. Accepting the Nobel Prize for this work in 1962, Watson cited one of Daly's papers on "The role of ribonucleoprotein in protein synthesis" as contributing to his work.{{cite web |last1=Watson |first1=James |title=James Watson – Nobel Lecture |publisher=Nobel Media |website=NobelPrize.org |url=https://www.nobelprize.org/prizes/medicine/1962/watson/lecture/ |access-date=7 November 2018}}{{cite journal |last1=Allfrey |first1=V |last2=Daly |first2=MM |last3=Mirsky |first3=AE |title=Synthesis of protein in the pancreas. II. The role of ribonucleoprotein in protein synthesis. |journal=The Journal of General Physiology |date=20 November 1953 |volume=37 |issue=2 |pages=157–75 |pmid=13109153 |pmc=2147435 |doi=10.1085/jgp.37.2.157 }} After 1953, the cell nucleus research field was flooded with funding opportunities.

=Cholesterol and hypertension=

Daly and her colleagues did some of the earliest work relating diet to the health of the cardiac and circulatory systems. They investigated the impact of cholesterol, sugar, and other nutrients.

She was the first to establish that hypertension was a precursor to atherosclerosis, and the first to identify a relationship between cholesterol and clogged arteries,{{cite news |last1=Lee |first1=D. N. |title=You Should Know: Dr. Marie Daly |url=https://blogs.scientificamerican.com/urban-scientist/you-should-know-dr-marie-daly/ |access-date=8 November 2018 |work=Scientific American |date=July 6, 2014}}

an important discovery in understanding how heart attacks occur.

She was especially interested in how hypertension affects the circulatory system. She showed that high cholesterol intake in diet led to clogged arteries, and that hypertension accelerated this effect. She studied the effects of diet on hypertension, and found that both cholesterol and sugar were related to hypertension.{{cite journal |last1=Freis |first1=Edward D. |title=Hypertension and Atherosclerosis |url=https://profiles.nlm.nih.gov/ps/access/XFBBGM.pdf |access-date=8 November 2018 |journal=The American Journal of Medicine| volume=46|number=5| pages=735–740 |date=May 1969|doi=10.1016/0002-9343(69)90024-2 |pmid=4892339 }}{{cite journal |last1=Deming |first1=QB |last2=Mosbach |first2=EH |last3=Bevans |first3=M |last4=Daly |first4=MM |last5=Abell |first5=LL |last6=Martin |first6=E |last7=Brun |first7=LM |last8=Halpern |first8=E |last9=Kaplan |first9=R |title=Blood pressure, cholesterol content of serum and tissues and atherogenesis in the rat. |journal=The Journal of Experimental Medicine |date=1 April 1958 |volume=107 |issue=4 |pages=581–98 |pmid=13513919 |pmc=2136835 |doi=10.1084/jem.107.4.581 }}{{cite book |last1=Deming |first1=Q.B. |last2=Brun |first2=L.M. |last3=Kaplan |first3=R. |last4=Daly |first4=M.M. |last5=Bloom |first5=J. |last6=Schechter |first6=M. |editor-last1=Brest |editor-first1=A.N. |editor-last2=Moyer |editor-first2=J.H. |title=The Second Hahnemann Symposium on Hypertensive Disease|chapter=Hypertension, Recent Advances |date=1961 |publisher=Lea & Febiger |location=Philadelphia |pages=160–}}{{cite journal |last1=Daly |first1=M. M. |title=Cholesterol Concentration and Cholesterol Synthesis in Aortas of Rats with Renal Hypertension |last2=Deming |first2=Q. B. |last3=Raeff |first3=V. M. |last4=Brun |first4=L. M. |journal=Journal of Clinical Investigation |date=1 October 1963 |volume=42 |issue=10 |pages=1606–1612 |doi=10.1172/JCI104845 |pmid=14074354 |pmc=289439 }}

Investigating aging, she suggested that smooth muscle hypertrophy due to aging might have a causative role in hypertension and atherosclerosis.{{cite book |last1=Kritchevky |first1=David |title=Lipids, Lipoproteins, and Drugs |date=1975 |publisher=Plenum Press |location=New York and London |pages=295 |url=https://books.google.com/books?id=mPkICAAAQBAJ&pg=PA295|isbn=9781468432589 }}

Daly was also an early investigator into the effects of cigarette smoke on the lungs and on hypertension.{{cite web|title=Marie Maynard Daly, biochemist|url=https://valentinaproject.wordpress.com/2014/04/01/marie-maynard-daly-biochemist/|website=The Valentina Project|access-date=21 March 2018|date=April 2014}}{{cite journal |last1=Park |first1=Sung Suh |last2=Kikkawa |first2=Yutaka |last3=Goldring |first3=Irene P. |last4=Daly |first4=Marie M. |last5=Zelefsky |first5=Melvin |last6=Shim |first6=Chang |last7=Spierer |first7=Morris |last8=Morita |first8=Toyohiko |title=An Animal Model of Cigarette Smoking in Beagle Dogs Correlative Evaluation of Effects on Pulmonary Function, Defense, and Morphology |journal=American Review of Respiratory Disease |date=June 1, 1977 |volume=115 |issue=6 |pages=971–9 |doi=10.1164/arrd.1977.115.6.971 |pmid=262108 |url=https://www.atsjournals.org/doi/abs/10.1164/arrd.1977.115.6.971 |access-date=8 November 2018|doi-broken-date=1 November 2024 }}

=Creatine=

In the 1970s Daly began studying the uptake of creatine by muscle cells, an important research topic in the energy recycling systems of muscle. Her "Uptake of Creatine by Cultured Cells" (1980) described the conditions under which muscle tissues best absorbed creatine.{{cite journal |last1=Daly |first1=Marie M. |last2=Seifter |first2=Sam |title=Uptake of creatine by cultured cells |journal=Archives of Biochemistry and Biophysics |date=August 1980 |volume=203 |issue=1 |pages=317–324 |doi=10.1016/0003-9861(80)90182-4 |pmid=740603 }}

Early life

There is limited information about her personal life and motivation for science.{{cite web |last1=Scudellari |first1=Megan |title=Marie Maynard Daly was a trailblazing biochemist, but her full story may be lost |url=https://www.sciencenews.org/article/marie-maynard-daly-biochemistry-chemistry-history |website=Science News |date=2 March 2022 |access-date=3 March 2022}} Daly's father, Ivan C. Daly, had immigrated from the British West Indies, found work as a postal clerk and eventually married Helen Page of Washington, D.C.{{cite web|title=Marie M. Daly|url=https://www.biography.com/people/marie-m-daly-604034|website=Biography|publisher=A&E Television Networks|access-date=21 March 2018}} They lived in New York City, and Daly was born and raised in Corona, Queens.{{cite book|last1=Kessler|first1=James|last2=Kidd|first2=J.S.|last3=Kidd|first3=Renee|last4=Morin|first4=Katherine A.|title=Distinguished African-American Scientists of the 20th Century|date=1996|publisher=Oryx Press|location=Phoenix, AZ|page=57|url=https://books.google.com/books?id=-ydHVdMUqdEC&pg=PA57|access-date=21 March 2018|isbn=9780897749558}} She often visited her maternal grandparents in Washington, where she read about scientists and their achievements in her grandfather's extensive library. She was especially impressed by Paul de Kruif's The Microbe Hunters, a work which influenced her decision to become a scientist.

Daly's interest in science was also influenced by her father, who had attended Cornell University with the intention of becoming a chemist, but had been unable to complete his education due to a lack of funds.{{cite book|last1=Grinstein|first1=Louise S.|last2=Rose|first2=R. K.|last3=Rafailovich|first3=M. H.|title=Women in chemistry and physics: a biobibliographic sourcebook|date=1993|publisher=Greenwood Press|location=Westport, Conn.|isbn=9780313273827|page=[https://archive.org/details/womeninchemistry00grin/page/149 149]|edition=1. publ.|url-access=registration|url=https://archive.org/details/womeninchemistry00grin/page/149}} Daly would thus complete her father's ambition by majoring in chemistry. Years later, she started a Queens College scholarship fund in his honor to assist minority students majoring in chemistry and or physics.{{cite web |title= Marie Maynard Daily |url= https://www.sciencehistory.org/historical-profile/marie-maynard-daly |website= Science History Institute |access-date= 20 March 2018|date= June 2016 }}

Daly married and took the name Marie Maynard Daly Clark. Her husband died before her and they did not have any children. She died on October 28, 2003.

Legacy

On February 26, 2016, the founding principal of the new elementary school P.S.360Q, Mr. R. Emmanuel-Cooke, announced that the school would be named "The Dr. Marie M. Daly Academy of Excellence" in honor of the Queens resident.{{cite web|title=PS 360Q PTA The Dr. Marie M. Daly Academy of Excellence|url=https://ps360qpta.ptboard.com/|website=PTBoard|access-date=21 March 2018}}{{cite web|last1=Bossing|first1=Jan|title=Marie M. Daly, first African-American woman to earn a Ph.D. in chemistry|url=https://medium.com/@JanBossing/amazing-women-d580cc590336|website=Amazing Women|access-date=May 31, 2016}} Additionally Einstein College also created an annual memorial lecture called The Marie M. Daly Memorial Celebration that is sponsored by the division of Biomedical Sciences and the Einstein Minority Scientist Association.{{Cite web |title=Marie M. Daly PhD Memorial Celebration |url=https://www.einsteinmed.edu/education/phd/current-students/events/Marie-Daly-Celebration.aspx |access-date=2022-04-23 |website=www.einsteinmed.edu}} Every year guest speakers are invited to give a lecture highlighting diversity and contribution of minorities to science.

Selected bibliography

  • {{cite journal |first1=Marie M. |last1=Daly |first2=A.E. |last2=Mirsky |author-link1=Marie Daly |title=Chromatography of Purines and Pyrimidines on Starch Columns |journal=Journal of Biological Chemistry |date=June 1949 |volume=179 |issue=2 |pages=981–982 |doi=10.1016/S0021-9258(19)51291-1 |pmid=18150028|doi-access=free }}
  • {{cite journal |first1=M.M. |last1=Daly |first2=V.G. |last2=Allfrey |first3=A.E. |last3=Mirsky |author-link1=Marie Daly |title=Purine and Pyrimidine Contents of Some Desoxypentose Nucleic Acids |url=https://rupress.org/jgp/article-pdf/33/5/497/1240452/497.pdf |journal=Journal of General Physiology |date=May 20, 1950 |volume=33 |issue=5 |pages=497–510 |pmid=15422104 |pmc=2147206 |doi=10.1085/jgp.33.5.497}}
  • {{cite journal |first1=Marie |last1=Daly |first2=A.E. |last2=Mirsky |first3=Hans |last3=Ris |author-link1=Marie Daly |title=The Amino Acid Composition and Some Properties of Histones |url=https://rupress.org/jgp/article-pdf/34/4/439/1240490/439.pdf |journal=The Journal of General Physiology |date=March 20, 1951 |volume=34 |issue=4 |pages=439–450 |pmid=14824510 |pmc=2147226 |doi=10.1085/jgp.34.4.439}}
  • {{cite journal |first1=Marie M. |last1=Daly |first2=A.E. |last2=Mirsky |author-link1=Marie Daly |title=Formation of Protein in the Pancreas |journal=Journal of General Physiology |date=November 1952 |volume=36 |issue=2 |pages=243–254 |pmid=13011280 |pmc=2147369 |doi=10.1085/jgp.36.2.243}}
  • {{cite journal |first1=Marie M. |last1=Daly |first2=V.G. |last2=Allfrey |first3=A.E. |last3=Mirsky |author-link1=Marie Daly |title=Uptake of Glycine-N15 by Components of Cell Nuclei |url=https://rupress.org/jgp/article-pdf/36/2/173/1240803/173.pdf |journal=Journal of General Physiology |date=November 1952 |volume=36 |issue=2 |pages=173–179 |pmid=13011275 |pmc=2147362 |doi=10.1085/jgp.36.2.173}}
  • {{cite journal|first1=V. |last1=Allfrey |first2=M.M. |last2=Daly |first3=A.E. |last3=Mirsky |author-link2=Marie Daly |title=Synthesis of protein in the pancreas. II. The role of ribonucleoprotein in protein synthesis. |journal=Journal of General Physiology |date=November 20, 1953 |volume=37 |issue=2 |pages=157–175 |pmid=13109153 |pmc=214743 |doi=10.1085/jgp.37.2.157}}
  • {{cite journal |first1=A.E. |last1=Mirsky |first2=V.G. |last2=Allfrey |first3=M.M. |last3=Daly |author-link3=Marie Daly |title=The Uptake of N15-Labelled Glycine by Liver Proteins |journal=Journal of Histochemistry and Cytochemistry |date=September 1954 |volume=2 |issue=5 |pages=376–377 |pmid=13192326 |doi=10.1177/2.5.376|s2cid=40223958 |doi-access=free }}
  • {{cite journal |first1=M.M. |last1=Daly |first2=A.E. |last2=Mirsky |author-link1=Marie Daly |title=Histones With High Lysine Content |journal=Journal of General Physiology |date=January 1955 |volume=38 |issue=3 |pages=405–413 |pmid=13221780 |pmc=2147486|doi=10.1085/jgp.38.3.405}}
  • {{cite journal |first1=V.G. |last1=Allfrey |first2=M.M. |last2=Daly |first3=A.E. |last3=Mirsky |author-link2=Marie Daly |title=Some Observations on Protein Metabolism in Chromosomes of Non-Dividing Cells |url=https://rupress.org/jgp/article-pdf/38/3/415/1192112/415.pdf |journal=Journal of General Physiology |date=January 20, 1955 |volume=38 |issue=3 |pages=415–424 |pmid=13221781 |pmc=2147482 |doi=10.1085/jgp.38.3.415}}
  • {{cite journal |first1=M.M. |last1=Daly |first2=V.G. |last2=Allfrey |first3=A.E. |last3=Mirsky |author-link1=Marie Daly |title=Synthesis of Protein in the Pancreas. III. Uptake of Glycine-N15 by the Trypsinogen and Chymotrypsinogen of Mouse Pancreas |url=https://rupress.org/jgp/article-pdf/39/2/207/1241093/207.pdf |journal=Journal of General Physiology |date=November 20, 1955 |volume=39 |issue=2 |pages=207–210 |pmid=13271721 |pmc=2147525 |doi=10.1085/jgp.39.2.207}}
  • {{cite journal |last1=Deming |first1=Q.B. |last2=Mosbach |first2=E.H. |last3=Bevans |first3=M. |last4=Daly |first4=M.M. |last5=Abell |first5=L.L. |last6=Martin |first6=E. |last7=Brun |first7=L.M. |last8=Halpern |first8=E. |last9=Kaplan |first9=R. |author-link4=Marie Daly |title=Blood Pressure, Cholesterol Content of Serum and Tissues and Atherogenesis in the Rat |url=https://rupress.org/jem/article-pdf/107/4/581/1079323/581.pdf |journal=The Journal of Experimental Medicine |date=April 1, 1958 |volume=107 |issue=4 |pages=581–598 |pmid=13513919 |pmc=2136835 |doi=10.1084/jem.107.4.581}}
  • {{cite journal |first1=Marie M. |last1=Daly |first2=E. Gambetta |last2=Gupride |author-link1=Marie Daly |title=The Respiration and Cytochrome Oxidase Activity of Rat Aorta in Experimental Hypertension| url=https://rupress.org/jem/article-pdf/109/2/187/1391182/187.pdf |journal=Journal of Experimental Medicine |date=February 1, 1959 |volume=109 |issue=2 |pages=187–195 |pmid=13620848 |pmc=2136939 |doi=10.1084/jem.109.2.187}}
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  • {{cite journal |first1=Harvey |last1=Wolinsky |first2=Marie M. |last2=Daly |title=A Method for the Isolation of Intima-Media Samples from Arteries |journal=Proceedings of the Society for Experimental Biology and Medicine |date=November 1970 |volume=135 |issue=2 |pages=364–368 |pmid=4921030 |doi=10.3181/00379727-135-35052|s2cid=46610507 }}
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  • {{cite journal |first1=Harvey |last1=Wolinsky |first2=Sidney |last2=Goldfischer |first3=Marie M. |last3=Daly |first4=Lisa E. |last4=Kasak |first5=Bernice |last5=Coltoff-Schiller |author-link3=Marie Daly |title=Arterial Lysosomes and Connective Tissue in Primate Atherosclerosis and Hypertension |journal=Circulation Research |date=April 1975 |volume=36 |issue=4 |pages=553–561 |pmid=1116247 |doi=10.1161/01.res.36.4.553|doi-access=free }}
  • {{cite journal |first1=M.M. |last1=Daly |author-link1=Marie Daly |title=Effects of age and hypertension on utilization of glucose by rat aorta |url=https://pubmed.ncbi.nlm.nih.gov/1251907/ |journal=American Journal of Physiology |date=January 1976 |volume=230 |issue=1 |pages=30–33 |pmid=1251907 |doi=10.1152/ajplegacy.1976.230.1.30}}
  • {{cite journal |last1=Park |first1=Sung Suh |last2=Kikkawa |first2=Yutaka |last3=Goldring |first3=Irene P. |last4=Daly |first4=Marie M. |last5=Zelefsky |first5=Melvin |last6=Shim |first6=Chang |last7=Spierer |first7=Morris |last8=Morita |first8=Toyohiko |author-link4=Marie Daly |title=An Animal Model of Cigarette Smoking in Beagle Dogs Correlative Evaluation of Effects on Pulmonary Function, Defense, and Morphology |url=https://www.atsjournals.org/doi/abs/10.1164/arrd.1977.115.6.971 |journal=American Review of Respiratory Disease |date=June 1, 1977 |volume=115 |issue=6 |pages=971–979 |doi=10.1164/arrd.1977.115.6.971 |pmid=262108 |access-date=8 November 2018|doi-broken-date=1 November 2024 }}
  • {{cite journal |first1=Marie M. |last1=Daly |first2=Sam |last2=Seifter |author-link1=Marie Daly |title=Uptake of creatine by cultured cells |url=https://www.sciencedirect.com/science/article/abs/pii/0003986180901824 |journal=Archives of Biochemistry and Biophysics |date=August 1980 |volume=203 |issue=1 |pages=317–324 |pmid=7406503 |doi=10.1016/0003-9861(80)90182-4}}
  • {{cite journal |first1=Marie M. |last1=Daly |author-link1=Marie Daly |title=Guanidinoacetate methyltransferase activity in tissues and cultured cells |url=https://pubmed.ncbi.nlm.nih.gov/3970526/ |journal=Archives of Biochemistry and Biophysics| date=February 1, 1985 |volume=236 |issue=2 |pages=576–584 |pmid=3970526 |doi=10.1016/0003-9861(85)90661-7}}

See also

References