Michele Vendruscolo

Vendruscolo is a graduate in physics of the University of Trieste (Italy).{{Cite web | url= https://www.ae-info.org/ae/Member/Vendruscolo_Michele/CV| title=CV details within the election to the Academia Europaea}} He received a Master of Science (MSc) and a PhD in condensed matter physics at the International School for Advanced Studies in Trieste, Italy. He then worked as a postdoctoral researcher, at the Weizmann Institute, Israel with Eytan Domany as a supervisor (1996–1998) and at the University of Oxford (1999–2001) under the supervision of Chris Dobson.

He was appointed as an independent academic at the University of Cambridge as a Royal Society University Research Fellow (2001), as a Lecturer (2006), and then as a Reader (2008) in Theoretical Chemical Biology. He is now Professor of Biophysics at the same university.{{Cite web|url= https://www.ch.cam.ac.uk/person/mv245|title=professorship at the University of Cambridge|access-date=30 September 2019}} He is also Director of Chemistry of Health, and Co-Director of the Centre for Misfolding Diseases at the University of Cambridge.{{Cite web|url= https://www.ch.cam.ac.uk/news/moving-our-new-chemistry-health-building| title=Director of Chemistry of Health and co-director of the Centre for Misfolding Diseases |access-date=30 September 2019}}

Vendruscolo provided contributions in the field of protein folding, misfolding and aggregation. He introduced the approach of simulating complex protein structures in transient or otherwise undetectable states (transition states, transient intermediates, transient aggregates, etc.) using exploitable experimental data as restraints.{{cite journal | vauthors = Cavalli A, Salvatella X, Dobson CM, Vendruscolo M| title = Protein structure determination from NMR chemical shifts| journal = PNAS| volume = 104 | issue = 23| pages = 9615–20 | date = 5 June 2007 | pmid = 17535901| pmc = 1887584| doi = 10.1073/pnas.0610313104| bibcode = 2007PNAS..104.9615C| doi-access = free}}{{cite journal | vauthors = Lindorff-Larsen K, Best RB, Depristo MA, Dobson CM, Vendruscolo M| title = Simultaneous determination of protein structure and dynamics| journal = Nature| volume = 433 | issue = 7022| pages = 128–32 | date = 13 January 2005 | pmid = 15650731| doi = 10.1038/nature03199| bibcode = 2005Natur.433..128L| s2cid = 15105531}} He edited computational programs able to predict essential characteristics of protein folding and protein aggregation.{{cite journal | vauthors = Tartaglia GG, Pawar AP, Campioni S, Dobson CM, Chiti F, Vendruscolo M | title = Prediction of aggregation-prone regions in structured proteins| journal = Journal of Molecular Biology | volume = 380 | issue = 2| pages = 425–36 | date = 4 July 2008 | pmid = 18514226| doi = 10.1016/j.jmb.2008.05.013| s2cid = 16410867}} In a collaboration with other scholars he dissected the process of Amyloid fibril formation in its microscopic steps and computed programs to analyse experimental kinetic time courses and study effects of Small molecules and other agents.{{cite journal | vauthors = Knowles TP, Vendruscolo M, Dobson CM | title = The amyloid state and its association with protein misfolding diseases | journal = Nature Reviews Molecular Cell Biology | volume = 15 | issue = 6 | pages = 384–96 | date = June 2014 | pmid = 24854788 | doi = 10.1038/nrm3810 | s2cid = 46357173 }}

• Election to EMBO Young Investigator program, European Molecular Biology Organization, 2008{{Cite web | url=https://yip-search.embo.org/#/yip/2480| title=Membership to EMBO Young Investigator Program to Michele Vendruscolo}}
• Soft Matter & Biophysical Chemistry Award, Royal Society of Chemistry, 2013{{Cite web|url=https://www.rsc.org/ScienceAndTechnology/Awards/SoftMatterBiophysicalChemistryAward/2013-Winner.asp | title= Soft Matter & Biophysical Chemistry Award to Michele Vendruscolo}}
• Election to member of Academia Europaea, 2017{{Cite web | url= https://www.ae-info.org/ae/Member/Vendruscolo_Michele/CV| title=Membership to Academia Europaea to Michele Vendruscolo}}
• Awarded Giuseppe Occhialini Medal and Prize, 2017{{cite web |url=https://www.iop.org/about/awards/bilateral/occhialini/medallists/page_38497.html |title=Occhialini medal recipients |website=www.iop.org |url-status=dead |archive-url=https://web.archive.org/web/20110309165948/http://www.iop.org/about/awards/bilateral/occhialini/medallists/page_38497.html |archive-date=2011-03-09}}
• Rita and John Cornforth Award, Royal Society of Chemistry, 2019{{Cite web|url=https://www.rsc.org/ScienceAndTechnology/Awards/RitaandJohnCornforthAward/2019-winners.asp| title= Rita and John Cornforth Award to Chris Dobson, Michele Vendruscolo and Tuomas Knowles}}

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{{Wikiquote}}

• [https://www.ch.cam.ac.uk/person/mv245/ Michele Vendruscolo’s homepage at University of Cambridge]
• [http://www-vendruscolo.ch.cam.ac.uk/ Michele Vendruscolo’s Laboratory]
• [https://www.cmd.ch.cam.ac.uk/ Centre for Misfolding Diseases]

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Category:1966 births

Category:Living people

Category:Fellows of the Royal Society of Chemistry

Category:21st-century Italian physicists

Category:Members of Academia Europaea

Category:People from Udine

Category:University of Trieste alumni