Viper (Madame Hydra)

Ophelia Sarkissian debuted in Captain America #110 (February 1969),{{Cite web |last=Abdulbaki |first=Mae |date=October 28, 2020 |title='Avengers 5' may feature a deadly spy teased in 'Falcon and Winter Soldier' |url=https://www.inverse.com/entertainment/avengers-5-falcon-winter-soldier-viper-madame-hydra |access-date=August 26, 2023 |website=Inverse |language=en}} created by Jim Steranko.{{cite book |last1=Brevoort |first1=Tom |last2=DeFalco |first2=Tom |last3=Manning |first3=Matthew K. |last4=Sanderson |first4=Peter |last5=Wiacek |first5=Win |title=Marvel Year By Year: A Visual History |date=2017 |publisher=DK Publishing |isbn=978-1465455505 |page=135}} She appeared in the 2016 Captain America: Steve Rogers series.{{Cite web |last=Adams |first=Tim |date=March 28, 2017 |title=Captain America: Hydra Cap's Cabinet of Supervillains Explained |url=https://www.cbr.com/captain-america-hydra-cabinet-explained-secret-empire/ |access-date=August 26, 2023 |website=Comic Book Resources |language=en}}{{Cite web |last=Lovett |first=Jamie |date=March 22, 2017 |title=Marvel Reveals New Hydra High Council |url=https://comicbook.com/marvel/news/captain-america-hydra-high-council-marvel/ |access-date=August 26, 2023 |website=ComicBook.com |language=en}} She appeared in the 2017 Secret Empire series.{{Cite web |last=Lovett |first=Jamie |date=November 9, 2017 |title=Captain America Introduces Hydra's Avengers |url=https://comicbook.com/marvel/news/secret-empire-avengers/ |access-date=August 26, 2023 |website=ComicBook.com |language=en}}{{Cite web |last= |first= |date=June 24, 2017 |title=The 15 Most WTF Moments From Secret Empire (So Far) |url=https://www.cbr.com/the-15-most-wtf-moments-from-secret-empire-so-far/ |access-date=August 26, 2023 |website=Comic Book Resources |language=en}} She appeared in the 2018 Hunt for Wolverine: Mystery in Madripoor series.{{Cite web |last=Lovett |first=Jamie |date=August 22, 2018 |title=Marvel Makes Major Change to X-Men Character |url=https://comicbook.com/marvel/news/x-men-psylocke-caucasian-body-swap-marvel-wolverine/ |access-date=August 26, 2023 |website=ComicBook.com |language=en}}{{Cite web |last=Terror |first=Jude |date=May 28, 2018 |title=X-ual Healing – It's Time for a Girls' Trip in Hunt for Wolverine: Mystery in Madripoor #1 |url=https://bleedingcool.com/comics/x-ual-healing-hunt-wolverine-madripoor-1/ |access-date=August 26, 2023 |website=Bleeding Cool |language=en}}

Ophelia Sarkissian was orphaned as a child in Hungary. Part of her face was scarred at one time, although it has since been healed. Among 12 other girls, Ophelia was taken in by HYDRA and raised by Kraken. For 22 years, Ophelia excelled and became Kraken's best student.Secret Warriors #15. Marvel Comics. She eventually rose through the ranks of HYDRA and frequently came into conflict with Captain America and the organization known as S.H.I.E.L.D. She first appeared as a leader of HYDRA under the codename Madame Hydra, and first fought and captured Captain America while trying to contaminate New York City's water supply.Captain America #110. Marvel Comics.{{cite book |last=Rovin |first=Jeff |title=The Encyclopedia of Super-Villains |date=1987 |publisher=Facts on File |isbn=0-8160-1356-X |location=New York |page=363 |authorlink=Jeff Rovin}}[https://archive.org/details/encyclopediaofsu0000rovi_h5r9/page/362/mode/2up] She captured Rick Jones to bait a trap for Captain America,Captain America #111. Marvel Comics. and then subdued the Avengers with gas, planning to bury the group alive, and battled Captain America again. However, she was apparently killed when Captain America and Jones dodged missiles she fired at the two and she was caught in their explosion.Captain America #113. Marvel Comics. Some time later, it was revealed that the Space Phantom had exchanged places with her and her whereabouts at the time were undisclosed.The Avengers #107. Marvel Comics.

She eventually severed her ties with HYDRA.Captain America #170 (February 1974). Marvel Comics. Madame Hydra helped the supervillain Viper (Jordan Stryke) escape custody in Virginia, only to proceed in assassinating Stryke and usurping the Viper alias and leadership of the Serpent Squad.Captain America #180 (Dec. 1974). Marvel Comics. As the second Viper, she kidnapped Roxxon president Hugh Jones, in order to put the latter in thrall of the Serpent Crown. She battled Nomad and Namor the Sub-Mariner.Captain America #181-182 (Jan.-Feb. 1975). Marvel Comics. Viper was the founder and leader of the elite criminal underworld through sheer ruthlessness, treachery, and the cunning of her black heart.

Viper took over the S.H.I.E.L.D. Helicarrier, and planned to crash it into the Congress building. She employed Boomerang and the Silver Samurai as operatives, and battled Spider-Man, Black Widow, Shang-Chi, and Nick Fury.Marvel Team-Up #83-85. Marvel Comics. Viper later employed the Silver Samurai as her chief operative, and attempted to kidnap Michael Kramer, a man carrying a fatal experimental disease, in order to release on America. Viper battled the first Spider-Woman, and became convinced that she was Merriam Drew, the mother of Spider-Woman who was considered deceased since 1931. The issue revealed Merriam had become allied to Chthon and was granted longevity in return. Viper revealed herself to have been a pawn of Chthon for 50 years, but saved Spider-Woman's life by defying Chthon.Spider-Woman #42-44 (February – June 1982). Marvel Comics. Viper, employing Constrictor as her chief operative, captured Spider-Woman, believing she was responsible for making her think they were related. It was revealed that Chthon had actually granted Viper false memories of mothering Jessica Drew as part of a plan to place both women under his control. Viper captured Captain America, and planned to release her new bubonic plague.Captain America #281-283 (May–July, 1983). Marvel Comics. Whether Viper actually has extraordinary longevity was left uncertain.

Re-employing the Silver Samurai, Viper attempted to coerce Team America into stealing the Cavourite Crystal, and then battled the New Mutants.The New Mutants #5-6. Marvel Comics. In one of her many terrorist acts, she would try to gain control of the snake-themed organization called the Serpent Society, with Slither, Copperhead, Puff Adder, Fer-De-Lance, and Black Racer as operatives. The latter four operatives infiltrated the Serpent Society in an attempt to take it over. Viper dispatched Cobra, Boomslang, and Copperhead to poison Washington D.C.'s water supply with a snake mutagen. Viper terrorized the White House and the President, and battled Captain America.Captain America #341-344. Marvel Comics. She attempted to assassinate the organization's former leader Sidewinder, but she was betrayed by Cobra and arrested by Captain America.Captain America #344. Marvel Comics. Viper was later freed from prison by Tyrannus. She used a snake mutagen on drug addicts, and then battled the Punisher.The Punisher Annual #2. Marvel Comics. She then turned against and battled Tyrannus.Daredevil Annual #4. Marvel Comics.

Madame Hydra has also been in conflict with the X-Men. She first came into contact with them upon trying to assassinate Mariko Yashida on behalf of her ally and presumed lover Silver Samurai, and tried to poison the team while disguised as Mariko's unconscious maid.The Uncanny X-Men #172 (Aug. 1983). Marvel Comics. She nearly killed X-Men members Rogue and Storm on two separate occasions, with Storm being nearly killed by Viper during the invasion of Khan.X-Treme X-Men #11. Marvel Comics. She also faced the New Mutants and was considered responsible for the presumed demise of Karma (Karma was only wounded and was abducted by the Shadow King for his own reasons).The New Mutants #6 (Aug. 1983). Marvel Comics.

Madame Hydra is a professional terrorist and has her own organization. She has come into conflict with many superheroes and supervillains over the years. Her nihilism and tendency to spread death around her has made it hard for other villains to associate with her. Only the Red Skull has found it a charming tendency and pursued a relationship with her for a while. The relationship ended when the Skull found out Viper was using his resources to finance massacres with no apparent financial benefit for either of them.Captain America #419 (Sept. 1993). Marvel Comics.

For a time, Viper employed a team of doppelgängers (known as "Pit-Vipers") to impersonate her. However, acting on her own, Pit-Viper 12{{Marvunapp|http://www.marvunapp.com/Appendix3/pitviper.htm|Pit-Viper}} became involved with the Punisher during an international crime conference in Las VegasThe Punisher War Journal #45-47 (Aug.–Oct. 1992). Marvel Comics. and later tipped off S.H.I.E.L.D. to the real Viper's attempt to steal Russian nuclear missiles in Moscow.Nick Fury, Agent of S.H.I.E.L.D. vol. 2 #45 (March 1993). Marvel Comics. For compromising her anonymity, the Viper personally killed her treacherous double.Silver Sable and the Wild Pack #15 (Aug. 1993). Marvel Comics.

Later she blackmailed Wolverine into marrying her as a means to secure her criminal empire in Madripoor. Although this was a marriage of convenience, she did request to consummate the arrangement. Some time later, her body was briefly inhabited by the spirit of Ogun, and Wolverine mortally wounded her as a means of driving the spirit from her dying body. In return for seeking medical attention to save her life, Wolverine demanded a divorce.Wolverine vol. 2 #125. Marvel Comics. It is later implied that she actually had feelings for Wolverine.Astonishing Tales vol. 2 #6. Marvel Comics.

Viper was then a member of an incarnation of the Hellfire Club, working with Courtney Ross, briefly under the title "White Warrior Princess".The Uncanny X-Men #452. Marvel Comics. She has also associated with the Hand and resumed her ties with the Silver Samurai. She has also retaken the name "Madame Hydra".{{Volume needed|c=y|date=June 2009}}

For a time, Viper was the dictator of the nation of Madripoor, using the nation's resources to support global terrorism via HYDRA.{{Volume needed|c=y|date=October 2009}} She was overthrown by new S.H.I.E.L.D. Director Tony Stark and Tyger Tiger, the latter of whom is now ruler of Madripoor.Iron Man Annual #1. Marvel Comics.

During the Dark Reign storyline, Viper is seen leaving her lover, the Silver Samurai, to rejoin Baron Strucker and the ruling council of HYDRA.Secret Warriors #2. Marvel Comics. It was revealed that she is no longer Madame Hydra, as she was replaced by Valentina Allegra de Fontaine taking up the mantle of Madame Hydra, wearing an elaborate tentacle headdress and elaborate HYDRA robes.Secret Warriors #3. Marvel Comics.

Viper is kidnapped by the mysterious group Leviathan, who are determined to find out the location of a mysterious box that both she and Madame Hydra procured from the Yashidas. Madame Hydra arrived at the Leviathan headquarters and offered the box to its leader, much to Viper's dismay. Madame Hydra then shot Viper to death. However, when HYDRA arrived, the Hive resurrected her, giving her tentacles that stemmed from her head, and she renamed herself Madame Hydra.Secret Warriors #12-15. Marvel Comics.

Following the Fear Itself storyline, Madame Hydra joins up with H.A.M.M.E.R. after Norman Osborn escapes from the Raft and regains leadership.The New Avengers vol. 2 #16.1. Marvel Comics. After the defeat of Osborn and the Dark Avengers, Madame Hydra uses the resources of the now-defunct H.A.M.M.E.R. to begin rebuilding HYDRA.The Avengers vol. 4 #24. Marvel Comics. She later tips off Spider-Woman and Hawkeye about a heist Mister Negative is planning on a S.H.I.E.L.D. warehouse. While the Avengers deal with Mister Negative, Madame Hydra attacks a different S.H.I.E.L.D. facility and steals several captive Skrulls left over from the Secret Invasion.The Avengers vol. 4 #30. Marvel Comics.

Madame Hydra later led an attack on Avengers Tower while the team is away. She and the rest of her forces are defeated by Angel and his younger self from earlier in the timestream.All-New X-Men #8. Marvel Comics.

In "Death of Wolverine", she was revealed by Nuke as the "Green Queen" and current leader of Madripoor who sent out a contract to capture Wolverine.Death of Wolverine #2. Marvel Comics.

Viper is part of the HYDRA High Council that the new Madame Hydra is collecting to assist Steve Rogers who had his history altered by the Red Skull's clone using Kobik's powers to be a HYDRA sleeper agent for years.Captain America: Steve Rogers #14. Marvel Comics.

During the "Secret Empire" storyline, Viper attends the meeting of the HYDRA High Council and talks about the opening of two new detention facilities to double the amount of Inhumans held in indefinite custody.Secret Empire #1. Marvel Comics. While doing business with some men, Viper is told by a HYDRA agent that they have apprehended Black Widow. This is part of a diversion so that the Champions can infiltrate a HYDRA base. When Viper figures out that Black Widow is planning to kill Hydra Supreme, Viper tries to persuade Black Widow to join up with her enterprise.Secret Empire #5. Marvel Comics.

During the "Hunt for Wolverine" storyline, Viper is seen in Madripoor where she leads the Femme Fatales (consisting of Knockout, Bloodlust, Mindblast, Snake Whip, and Sapphire Styx) into ambushing Kitty Pryde, Domino, Jubilee, Psylocke, and Storm at the King's Impresario Restaurant. While Psylocke, Rogue, and Storm are defeated and taken prisoner by Madame Hydra and the Femme Fatales, Pryde escapes with Domino and Jubilee.Hunt for Wolverine: Mystery in Madripoor #1. Marvel Comics. Viper congratulates the Femme Fatales for their work as they now have Psylocke, Rogue, and Storm as their prisoners. Mindblast suggests that they put a bounty on the ones that escaped, stating that every gang member in Lowtown will be looking for them. Viper states that she will discuss with her client on where to proceed next and to deposit Rogue and Storm to the client as "special guests." As Viper gives the status report to a representative of her client, she mentions that Sapphire Styx is still draining off of Psylocke just like she did with Magneto. The representative tells Viper that Sapphire Styx tends to prefer the life force of the mutants and tells Viper to focus on delivering the package as all that they are serves the will of Soteira. As Snake Whip asks if they are going to ignore Sapphire Styx's vampiric appetite, Viper says that they have to obey the representative's orders and "let the @#$%& feed."Hunt for Wolverine: Mystery in Madripoor #2. Marvel Comics. Viper is contacted by a representative of Soteira who was displeased that the launch was delayed by a torrential rainstorm and suggest that they launch before sunrise. While reluctantly taking the representative's suggestion, Viper and Snake Whip check up on Sapphire Styx who knocks down Snake Whip and claims that Wolverine's Patch alias is present even though Sapphire is the only one who can see him. Viper calls Knockout and Mindblast away from the prisoners to help deal with Sapphire. After hearing that the launch site for the rocket bound for Soteira is under attack, Viper gives the orders to launch it now.Hunt for Wolverine: Mystery in Madripoor #3. Marvel Comics. After Sapphire Styx explodes, Viper maintains the higher ground while Snake Whip joins the fight. When the Femme Fatales are defeated, Viper flees as Magneto plans to pursue her to purge Madripoor of Viper's criminal empire.Hunt for Wolverine: Mystery in Madripoor #4. Marvel Comics.

In the Ravencroft miniseries, Viper is seen as a member of J.A.N.U.S.Ravencroft #5. Marvel Comics.

Ophelia Sarkissian's strength, speed, reflexes, agility, dexterity, coordination, balance and endurance are on the order of an Olympic athlete. She is a great swordsman and even greater marksman with most long range weapons, and has extensive training in hand-to-hand combat. Viper occasionally employs poisoned weapons with snake-motifs, such as venomous darts or artificial fangs filled with poison.{{Cite web |last=Raymond |first=Charles Nicholas |date=April 21, 2017 |title=Agents Of S.H.I.E.L.D.: 15 Things You Should Know About Madame Hydra |url=https://screenrant.com/agents-of-shield-madame-hydra-viper-facts/ |access-date=November 8, 2022 |website=Screen Rant |language=en-US}} She utilizes experimental weaponry, including a ring that enables teleportation, and in X-Treme X-Men, she made use of razor-sharp claw attachments apparently built into her gloves. A brilliant strategist and tactician with extensive combat tactical experience, Ophelia Sarkissian is highly skilled in the management of criminal organizations and very well connected in the international criminal underworld. She is also a master of stealth and espionage. Perhaps her greatest strengths are her influence, the financial resources at her disposal due to her stature in organized crime, and an uncanny luck which has allowed her to cheat death in situations where lesser people would have died. Ophelia Sarkissian may or may not have supernaturally augmented longevity.

Ophelia Sarkissian is usually armed with various ray pistols and conventional handguns. She has also used various other special weaponry, including poison-tipped throwing darts, knives, and whips. She has sharpened and elongated canine teeth with hollows inside them. She keeps a special poison in them, to which she has an immunity.

Kai Young of Screen Rant called Ophelia Sarkissian "one of the most recognizable villains in the Marvel Universe."{{Cite web |last=Young |first=Kai |date=June 19, 2023 |title=10 Captain America Villains Still Missing From The MCU |url=https://screenrant.com/captain-america-villains-missing-from-mcu/ |access-date=August 26, 2023 |website=Screen Rant |language=en}} Marc Buxton of Den of Geek included Ophelia Sarkissian in their "Greatest Wolverine Villains" list.{{Cite web |last=Buxton |first=Marc |date=March 1, 2017 |title=Logan: The Greatest Wolverine Villains |url=https://www.denofgeek.com/comics/logan-the-greatest-wolverine-villains/ |access-date=March 25, 2023 |website=Den of Geek |language=en-US}} Jesse Schedeen of IGN ranked Ophelia Sarkissian 21st in their "Top 25 Marvel Villains" list.{{Cite web |last1=Schedeen |first1=Jesse |last2=Yehl |first2=Joshua |date=March 27, 2019 |title=The Top 25 Marvel Villains |url=https://www.ign.com/articles/2019/03/27/top-25-marvel-villains |access-date=November 8, 2022 |website=IGN |language=en}} Comic Book Resources ranked Ophelia Sarkissian 2nd in their "10 Most Powerful Crime Bosses In Marvel Comics" list,{{Cite web |last=Avina |first=Anthony |date=January 6, 2020 |title=The 10 Most Powerful Crime Bosses In Marvel Comics, Ranked |url=https://www.cbr.com/marvel-comics-most-powerful-crime-bosses-maggia-mobsters-organized-kingpin-ranked-compared/ |access-date=November 8, 2022 |website=Comic Book Resources |language=en-US}} 2nd in their "Marvel: The Council Of Hydra Members" list,{{Cite web |last=Chrysostomou |first=George |date=December 5, 2020 |title=Marvel: The Council Of Hydra Members, Ranked |url=https://www.cbr.com/marvel-council-hydra-members-ranked/ |access-date=November 8, 2022 |website=Comic Book Resources |language=en-US}} 7th in their "10 Most Attractive Marvel Villains" list,{{Cite web |last=Parker |first=Thayer Preece |date=October 19, 2022 |title=10 Most Attractive Marvel Villains |url=https://www.cbr.com/marvel-villains-most-attractive/ |access-date=November 8, 2022 |website=Comic Book Resources |language=en-US}} and 7th in their "Marvel Comics: Ranking 10 Members Of Hydra From Weakest To Most Powerful" list.{{Cite web |last=Avina |first=Anthony |date=January 23, 2020 |title=Marvel Comics: Ranking 10 Members Of Hydra From Weakest To Most Powerful |url=https://www.cbr.com/marvel-comics-ranking-hydra-most-powerful/ |access-date=November 8, 2022 |website=Comic Book Resources |language=en-US}}

An alternate universe variant of Ophelia Sarkissian from Earth-295 appears in Age of Apocalypse. This version was married to the Silver Samurai and was killed saving him from Apocalypse's Infinites.{{Volume needed|c=y|date=June 2009}}

An alternate universe variant of Madame Hydra from Earth-1720, Susan Storm, appears in Exiles.Exiles #91 (February 2007). Marvel Comics.

An alternate version of Ophelia Sarkissian from Earth-1610 appears in Ultimatum: Spider-Man Requiem #1Ultimatum: Spider-Man Requiem #1 (June 2009). Marvel Comics.

An alternate universe variant of Viper from Earth-6160 appears in Ultimate Invasion. This version is the leader of several territories in Japan and a member of the Maker's Council.Ultimate Invasion #2. Marvel Comics.Ultimate Invasion #3. Marvel Comics.Ultimate Invasion #4. Marvel Comics.

• Viper appears in the X-Men: Evolution episode "Target X", voiced by Lisa Ann Beley. This version is the leader of Hydra and is responsible for creating X-23.{{cite episode |last1=Paur| first1=Frank| author-link1=Frank Paur| last2=Kyle| first2=Craig| author-link2=Craig Kyle| last3=Yost | first3= Christopher| author-link3=Christopher Yost|date=September 13, 2003 |title=Target X |series=X-Men: Evolution |season=4 |issue=3 |language=English |publisher=Marvel Entertainment |network=Kids' WB}}
• Madame Viper/Madame Hydra, a character with elements of both Viper and Valentina Allegra de Fontaine, appears in The Avengers: Earth's Mightiest Heroes, voiced by Vanessa Marshall.{{cite episode |last1=Heuck| first1=Vinton| last2=Burke| first2=Kevin| last3=Wyatt| first3= Chris| author-link3=Chris Wyatt (producer) |date=December 19, 2010 |title=Widow's Sting |series=The Avengers: Earth's Mightiest Heroes |season=1 |issue=11 |language=English |publisher=Marvel Animation |network=Disney XD}}{{Cite web |last=Nguyen |first=Richie |date=April 15, 2020 |title=The 10 Best Episodes of Avengers: Earth's Mightiest Heroes (According To IMDb) |url=https://www.cbr.com/avengers-earths-mightiest-heroes-imdb-top-episodes/ |access-date=August 26, 2023 |website=Comic Book Resources |language=en}}{{cite web |title=Madame Hydra Voices (Captain America) |url=https://www.behindthevoiceactors.com/characters/Captain-America/Madame-Hydra/ |access-date=January 28, 2024 |publisher=Behind The Voice Actors}} A green check mark indicates that a role has been confirmed using a screenshot (or collage of screenshots) of a title's list of voice actors and their respective characters found in its credits or other reliable sources of information. This version is an agent of HYDRA and an associate of the Serpent Society.
• A version of the character, Aida / "Ophelia" / Madame Hydra, appears in Agents of S.H.I.E.L.D., portrayed by Mallory Jansen. This version is a Life Model Decoy, an android body based on Holden Radcliffe's former lover and partner Agnes Kitsworth into which he transferred his artificial intelligence AIDA.{{Cite magazine |last=Abrams |first=Natalie |date=April 1, 2017 |title=Madame Hydra to appear on Agents of S.H.I.E.L.D. — first look |url=https://ew.com/tv/2017/04/01/agents-shield-madame-hydra/ |url-status=live |magazine=Entertainment Weekly |archive-url=https://web.archive.org/web/20170402005529/http://ew.com/tv/2017/04/01/agents-shield-madame-hydra/ |archive-date=April 2, 2017 |access-date=April 2, 2017}}{{Cite magazine |last=Holub |first=Christian |date=April 11, 2017 |title=Agents of S.H.I.E.L.D. recap: 'Identity and Change' |url=https://ew.com/recap/marvels-agents-of-shield-season-4-episode-17/ |url-status=live |magazine=Entertainment Weekly |archive-url=https://web.archive.org/web/20170412154548/http://ew.com/recap/marvels-agents-of-shield-season-4-episode-17/ |archive-date=April 12, 2017 |access-date=April 11, 2017}}

Viper appears in 20th Century Fox's The Wolverine, portrayed by Svetlana Khodchenkova.{{Cite web |author1=Rich |first=Katey |date=October 10, 2012 |title=The Wolverine Set Photos Reveal Svetlana Khodchenkova As Viper |url=https://www.cinemablend.com/new/Wolverine-Set-Photos-Reveal-Svetlana-Khodchenkova-Viper-33476.html |access-date=August 26, 2023 |website=CinemaBlend |language=en}}{{Cite web |last=Weintraub |first=Steve |date=May 28, 2013 |title=Svetlana Khodchenkova Talks Playing Viper, Landing the Role, and More on the WOLVERINE Set |url=https://collider.com/svetlana-khodchenkova-the-wolverine-interview/ |access-date=August 26, 2023 |website=Collider |language=en}} Due to rights issues with Marvel Studios at the time, this version is not referred to as "Madame Hydra" nor is her affiliation with the organization referenced.{{Cite web |last=Fink |first=Richard |date=March 2, 2023 |title=X-Men Comics That Inspired the Movies |url=https://movieweb.com/x-men-comics-inspired-movies/ |access-date=August 26, 2023 |website=MovieWeb |language=en}} Instead, she is depicted as a mutant scientist known as "Dr. Green", who is immune to toxins, can shed her skin, produce acidic saliva, and is a master of toxins. Ichiro Yashida hires Viper to help transfer Logan's healing factor to the former as well as monitor Kenuichio Harada's ninja clan. Viper is later killed while fighting Yukio.

• Ophelia Sarkissian / Madame Hydra appears as a boss in Captain America: Super Soldier, voiced by Audrey Wasilewski.
• Ophelia Sarkissian / Viper appears as the first boss of Marvel: Avengers Alliance.{{citation needed|date=October 2023}}
• Ophelia Sarkissian / Viper appears as a boss in Marvel: Avengers Alliance Tactics.{{citation needed|date=October 2023}}
• Ophelia Sarkissian / Madame Hydra appears in Marvel Heroes, voiced by Tasia Valenza.
• Ophelia Sarkissian / Viper appears in Lego Marvel Super Heroes,{{Cite web |last=Brown |first=Luke |date=July 30, 2013 |title=Wolverine Stars in New Lego Marvel Super Heroes Screenshots |url=https://screencrush.com/wolverine-stars-in-new-lego-marvel-super-heroes-screenshots/ |access-date=August 26, 2023 |website=ScreenCrush |language=en}}{{Cite web |last=Melrose |first=Kevin |date=July 29, 2013 |title='LEGO Marvel Super Heroes' spotlights Wolverine, Viper & more |url=https://www.cbr.com/lego-marvel-super-heroes-spotlights-wolverine-viper-more/ |access-date=August 26, 2023 |website=Comic Book Resources |language=en}}{{Cite web |last=Martin |first=Liam |date=July 30, 2013 |title=LEGO Marvel screens: Wolverine, Viper |url=https://www.digitalspy.com/videogames/a502607/new-lego-marvel-super-heroes-screens-show-wolverine-viper-more/ |access-date=August 26, 2023 |website=Digital Spy |language=en-GB}} voiced by Kari Wahlgren.{{citation needed|date=November 2013}}
• Ophelia Sarkissian / Viper appears in Lego Marvel's Avengers.{{citation needed|date=February 2017}}
• Ophelia Sarkissian / Madame Hydra appears as a boss in Marvel Avengers Academy.{{citation needed|date=January 2024}}
• Ophelia Sarkissian / Madame Hydra appears in Marvel Powers United VR, voiced again by Vanessa Marshall.
• Ophelia Sarkissian / Viper appears as a playable character in Marvel: Future Fight.{{Cite web |last=Paige |first=Rachel |date=February 13, 2020 |title=Hydra has Invaded MARVEL Future Fight |url=https://www.marvel.com/articles/games/marvel-future-fight-hydra-update |access-date=August 26, 2023 |website=Marvel.com}}{{Cite web |last=Sheehan |first=Gavin |date=February 14, 2020 |title="Marvel Future Fight" Gets A Secret Empire Update With New Costumes |url=https://bleedingcool.com/games/marvel-future-fight-gets-a-secret-empire-update-with-new-costumes/ |access-date=August 26, 2023 |website=Bleeding Cool |language=en}}
• Ophelia Sarkissian / Viper appears in Marvel Snap.{{Cite web |last=Steel |first=Tom |date=June 24, 2023 |title=10 Most Underrated Cards In Marvel Snap, Ranked |url=https://www.cbr.com/marvel-snap-best-overlooked-cards/ |access-date=August 26, 2023 |website=Comic Book Resources |language=en}}{{Cite web |last=Buchalter |first=Jacob H. |date=January 6, 2023 |title=Marvel Snap: Best Cards for the Right Location |url=https://gamerant.com/marvel-snap-best-cards-right-location/ |access-date=August 26, 2023 |website=Game Rant |language=en}}

In 2022, Hasbro released an Ophelia Sarkissian / Madame Hydra action figure as part of the Marvel Legends action figure line.{{Cite web |last=Fallon |first=Sean |date=February 22, 2022 |title=Marvel Legends Controller Build-A-Figure Wave and Retro Rhino Pre-Orders Drop Today |url=https://comicbook.com/marvel/news/marvel-legends-controller-build-a-figure-wave-and-retro-rhino-pre-orders-drop-today/ |access-date=August 26, 2023 |website=ComicBook.com |language=en}}{{Cite web |last=Konrad |first=Jeremy |date=February 21, 2022 |title=Marvel Legends First Livestream Of 2022 Reveals Galore |url=https://bleedingcool.com/collectibles/marvel-legends-reveals-ultron-rhino-blue-marvel-quake-pulse/ |access-date=August 26, 2023 |website=Bleeding Cool |language=en}}

• Ophelia Sarkissian / Madame Hydra appears in the Spider-Woman: Agent of S.W.O.R.D. motion comic, voiced by Nicolette Reed.
• Ophelia Sarkissian / Madame Hydra appears in Marvel Universe Live!.{{cite web |title=New Images Reveal the Superheroines of 'Marvel Universe Live!' |url=http://comicsalliance.com/superheroines-concept-art-marvel-universe-live/ |url-status=dead |archive-url=https://web.archive.org/web/20140717040913/http://comicsalliance.com/superheroines-concept-art-marvel-universe-live/ |archive-date=July 17, 2014 |access-date=June 29, 2014 |website=Comics Alliance}}

{{Reflist|30em}}

• {{Marvelwiki|viper-madame-hydra|Viper (Madame Hydra)}}
• {{Marveldatabase|Viper}}
• [https://web.archive.org/web/20021003142317/http://www.geocities.com/Hollywood/2855/viper.html Viper's Profile] at The Women of Marvel Comics
• {{Marvunapp|http://www.marvunapp.com/Appendix4/madame_hydra_viper.htm|Viper}}
• {{Marvunapp|http://www.marvunapp.com/Appendix3/madamehydra.htm|Madame Hydra VI}}
• [http://uncannyxmen.net/characters/values-of-a-viper Values of a Viper] at UncannyXmen.net

{{Captain America characters}}

{{Nick Fury}}

{{Spider-Woman}}

{{Wolverine}}

{{X-Men characters}}

Category:Captain America characters

Category:Characters created by Jim Steranko

Category:Comics characters introduced in 1969

Category:Fictional female gangsters

Category:Fictional female murderers

Category:Fictional Hungarian people

Category:Hydra (comics) agents

Category:Marvel Comics characters who can teleport

Category:Marvel Comics female supervillains

Category:Marvel Comics martial artists

Category:Marvel Comics orphans

Category:Marvel Comics television characters

Category:Villains in animated television series

Category:Wolverine (comics) characters