chromosome 20

The following are some of the gene count estimates of human chromosome 20. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.{{cite journal| author=Pertea M, Salzberg SL| title=Between a chicken and a grape: estimating the number of human genes. | journal=Genome Biol | year= 2010 | volume= 11 | issue= 5 | pages= 206 | pmid=20441615 | doi=10.1186/gb-2010-11-5-206 | pmc=2898077 | doi-access=free }}

{{Category see also|Genes on human chromosome 20}}

The following is a partial list of genes on human chromosome 20. For complete list, see the link in the infobox on the right.

{{columns-list|

• ADA: Adenosine Deaminase (Adenosine Deaminase Deficiency)
• ANDP: encoding protein Activity-dependent neuroprotector homeobox
• AHCY: S-adenosylhomocysteine hydrolase
• APMAP: encoding protein Adipocyte plasma membrane-associated protein
• ARFGEF2: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
• BCAS1: Breast carcinoma-amplified sequence 1
• BLCAP: Bladder cancer associated protein
• BMP2: Bone Morphogenetic Protein 2 (osteoblast differentiation)
• BPIFA1: encoding protein BPI fold containing family A, member 1
• BPIFA2: encoding protein BPI fold containing family A, member 2
• BPIFA3: encoding protein BPI fold containing family A, member 3
• BPIFA4P: non-coding pseudogene of the BPI fold containing family A, member 4P
• BPIFB1: encoding protein BPI fold containing family B, member 1
• BPIFB2: encoding protein BPI fold containing family B, member 2
• BPIFB3: encoding protein BPI fold containing family B, member 3
• BPIFB4: encoding protein BPI fold containing family B, member 4
• BPIFB5P: non-coding pseudogene of the BPI fold containing family B, member 5P
• BPIFB6: encoding protein BPI fold containing family B, member 6
• BPIFB9P: non-coding pseudogene of the BPI fold containing family B, member 9P
• C20orf27: encoding protein UPF0687 protein C20orf27
• CSRP2BP: encoding protein CSRP2 binding protein
• CST9L: Cystatin-9-like
• CSTL1: Cystatin-like 1
• CTCFL: CCCTC-binding factor-like
• CTNNBL1: Beta-catenin-like protein 1
• DBNDD2: Dysbindin domain-containing protein 2
• DDX27: DEAD box polypeptide 27
• DEFB118, DEFB119, DEFB126, DEFB127, DEFB129: Beta-defensin genes
• DLGAP4: Disks large-associated protein 4
• DNAJC5: Cysteine string protein
• EDEM2: ER degradation-enhancing alpha-mannosidase-like 2
• EDN3: endothelin 3
• ENTPD6: Ectonucleoside triphosphate diphosphohydrolase 6
• ESF1: ESF1 nucleolar pre-rRNA processing protein homolog
• FAM210B: encoding protein FAM210B
• FASTKD5: encoding protein FAST kinase domain-containing protein 5 (FASTKD5)
• FITM2: encoding protein Fat storage-inducing transmembrane protein 2
• GZF1: encoding protein GDNF-inducible zinc finger protein 1
• GMEB2: Glucocorticoid modulatory element-binding protein 2
• GNAS1: Gs alpha subunit (membrane G-protein)
• GSS: glutathione synthetase
• HSPA12B: encoding protein Heat shock protein family a (hsp70) member 12b
• ITPA: encoding enzyme Inosine triphosphate pyrophosphatase
• JAG1: jagged 1 (Alagille syndrome)
• JPH2: encoding protein Junctophilin 2
• KIAA1755: encoding protein Kiaa1755
• KIZ: encoding protein Kizuna centrosomal protein
• Kua-UEV:
• L3MBTL: encoding protein Lethal(3)malignant brain tumor-like protein
• LIME1: encoding protein Lck-interacting transmembrane adapter 1
• LZTS3: encoding protein Leucine zipper, putative tumor suppressor family member 3
• MIR124-3: encoding protein MIR124-3
• MIR499A: encoding protein MicroRNA 499a
• MROH8: encoding protein maestro heat like repeat family member 8
• NAPB: encoding protein Beta-soluble NSF attachment protein
• NDUFAF5: encoding protein NADH:ubiquinone oxidoreductase complex assembly factor 5
• Nnat: encoding protein Neuronatin
• NOL5A: encoding protein Nucleolar protein 56
• NRSN2: encoding protein Neurensin-2
• OCSTAMP: encoding protein Osteoclast stimulatory transmembrane protein
• OTOR: encoding protein Otoraplin
• OXT: encoding protein Oxytocin/neurophysin i prepropeptide
• PANK2: pantothenate kinase 2 (pantothenate kinase-associated neurodegeneration)
• PKIG: encoding protein cAMP-dependent protein kinase inhibitor gamma
• PLAGL2: encoding protein Zinc finger protein PLAGL2
• POLR3F: encoding enzyme DNA-directed RNA polymerase III subunit RPC6
• PRIC285:
• PRNP: prion protein (p27-30) (Creutzfeldt–Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)
• PXMP4: encoding protein Peroxisomal membrane protein 4
• R3HDML: encoding protein R3H domain containing-like
• RTF2: encoding protein RTF2 homolog
• SALL4: sal-like 4 (Drosophila)
• SERINC3: encoding protein Serine incorporator 3
• SHLD1: encoding protein Shieldin complex subunit 1
• SLC17A9: encoding protein Solute carrier family 17 member 9
• SLC2A4RG: encoding protein SLC2A4 regulator
• SLX4IP: encoding protein SLX4 interacting protein
• SNPH: encoding protein Syntaphilin
• SPATA2: encoding protein Spermatogenesis-associated protein 2
• SPEF1: encoding protein Sperm flagellar protein 1
• SRXN1: encoding protein Sulfiredoxin-1
• STAU1: encoding protein Double-stranded RNA-binding protein Staufen homolog 1
• STK35L1: encoding protein STK35L1
• SUN5: encoding protein SUN domain-containing protein 5
• TASP1: encoding enzyme Threonine aspartase 1
• tTG: tissue transglutaminase (auto antigen of Celiac disease)
• TMEPAI: encoding protein Transmembrane prostate androgen-induced protein
• TTPAL: encoding protein Tocopherol (alpha) transfer protein-like
• UCKL1: encoding enzyme Uridine-cytidine kinase-like 1
• UQCC: encoding enzyme Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog
• VAPB: VAMP (vesicle-associated membrane protein)-associated protein B and C
• YTHDF1: encoding protein YTH domain family, member 1
• ZFP64 encoding protein Zinc finger protein 64 homolog, isoforms 1 and 2
• ZGPAT: encoding protein Zinc finger CCCH-type with G patch domain-containing protein
• ZHX3: encoding protein Zinc fingers and homeoboxes protein 3
• ZNF334: encoding protein Zinc finger protein 334
• ZNF343: encoding protein Zinc finger protein 343
• ZSWIM3: encoding protein Zinc finger SWIM-type containing 3
• ZMYND8: encoding enzyme Protein kinase C-binding protein 1
• ZNF133: encoding protein Zinc finger protein 133

}}

The following diseases are some of those related to genes on chromosome 20:{{cite journal | author=Gilbert F | title=Disease genes and chromosomes: disease maps of the human genome | journal=Genet Test | year=1997 | pages=225–229 | volume=1 | issue=3 | pmid=10464650 | doi=10.1089/gte.1997.1.225}}

• Albright's hereditary osteodystrophy
• Arterial tortuosity syndrome
• Adenosine deaminase deficiency
• Alagille syndrome
• Galactosialidosis - CTSA
• Maturity onset diabetes of the young type 1
• Neuronal ceroid lipofuscinosis
• Pantothenate kinase-associated neurodegeneration
• Waardenburg syndrome
• CARASAL

{{multiple image

| header = G-banding ideograms of human chromosome 20

| total_width = 400

| image1 = Human chromosome 20 ideogram vertical.svg

| width1 = 216

| height1= 1125

| caption1 = G-banding ideogram of human chromosome 20 in resolution 850 bphs. Band length in this diagram is proportional to base-pair length. This type of ideogram is generally used in genome browsers (e.g. Ensembl, UCSC Genome Browser).

| image2 = Human chromosome 20 - 400 550 850 bphs.png

| width2 = 1003

| height2= 2801

| caption2 = G-banding patterns of human chromosome 20 in three different resolutions (400,Genome Decoration Page, NCBI. [http://ftp.ncbi.nlm.nih.gov/pub/gdp/ideogram_9606_GCF_000001305.14_400_V1 Ideogram data for Homo sapience (400 bphs, Assembly GRCh38.p3)]. Last update 2014-03-04. Retrieved 2017-04-26. 550Genome Decoration Page, NCBI. [http://ftp.ncbi.nlm.nih.gov/pub/gdp/ideogram_9606_GCF_000001305.14_550_V1 Ideogram data for Homo sapience (550 bphs, Assembly GRCh38.p3)]. Last update 2015-08-11. Retrieved 2017-04-26. and 850Genome Decoration Page, NCBI. [http://ftp.ncbi.nlm.nih.gov/pub/gdp/ideogram_9606_GCF_000001305.14_850_V1 Ideogram data for Homo sapience (850 bphs, Assembly GRCh38.p3)]. Last update 2014-06-03. Retrieved 2017-04-26.). Band length in this diagram is based on the ideograms from ISCN (2013).{{cite book|author=International Standing Committee on Human Cytogenetic Nomenclature|title=ISCN 2013: An International System for Human Cytogenetic Nomenclature (2013)|url=https://books.google.com/books?id=lGCLrh0DIwEC|year=2013|publisher=Karger Medical and Scientific Publishers|isbn=978-3-318-02253-7}} This type of ideogram represents actual relative band length observed under a microscope at the different moments during the mitotic process.{{cite book|last1=Sethakulvichai|first1=W.|last2=Manitpornsut|first2=S.|last3=Wiboonrat|first3=M.|last4=Lilakiatsakun|first4=W.|last5=Assawamakin|first5=A.|last6=Tongsima|first6=S.|title=2012 Ninth International Conference on Computer Science and Software Engineering (JCSSE) |chapter=Estimation of band level resolutions of human chromosome images |year=2012|pages=276–282|doi=10.1109/JCSSE.2012.6261965|isbn=978-1-4673-1921-8|s2cid=16666470|chapter-url=https://www.researchgate.net/publication/261304470}}

}}

{{reflist}}

{{Commons category|Human chromosome 20}}

• {{cite web | author= National Institutes of Health | title= Chromosome 20 | work= Genetics Home Reference | url= http://ghr.nlm.nih.gov/chromosome=20 | archive-url= https://web.archive.org/web/20040803053315/http://ghr.nlm.nih.gov/chromosome=20 | url-status= dead | archive-date= August 3, 2004 | access-date= 2017-05-06 }}
• {{Cite web|url=http://web.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/chromo20.shtml|title=Chromosome 20|website=Human Genome Project Information Archive 1990–2003|access-date=2017-05-06}}

{{Chromosomes}}

{{Chromosome genetics}}

{{DEFAULTSORT:Chromosome 20 (Human)}}

Category:Chromosomes (human)

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