Andrew Wakefield#Epidemics, effects, and reception
{{Short description|British former doctor (born 1956)}}
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{{Infobox person
| name = Andrew Wakefield
| image = Andrew Wakefield 2019 (cropped).jpg
| caption = Wakefield at an anti-vaccine rally in Warsaw, Poland, in 2019
| birth_name = Andrew Jeremy Wakefield
| birth_date = {{birth date and age|1956|9|03|df=y}}
| birth_place = Canadian Red Cross Memorial Hospital, Taplow, Buckinghamshire, England
| education = King Edward's School, Bath
| alma_mater = St Mary's Hospital Medical School, London
| partner = Elle Macpherson (2017–2019){{cite web |last=Hansen |first=Jane |title=Elle Macpherson's new life with world's most notorious anti-vaxxers |website=news.com.au |date=21 February 2021 |url=https://www.news.com.au/entertainment/celebrity-life/elle-macphersons-new-life-with-andrew-wakefield-and-the-worlds-most-notorious-antivaxxers/news-story/c3639dc7d31dd117ee70d1ee38a8d45c |access-date=30 December 2021 |archive-date=30 December 2021 |archive-url=https://web.archive.org/web/20211230192719/https://www.news.com.au/entertainment/celebrity-life/elle-macphersons-new-life-with-andrew-wakefield-and-the-worlds-most-notorious-antivaxxers/news-story/c3639dc7d31dd117ee70d1ee38a8d45c |url-status=live }}{{cite web |last=Duff |first=Seamus |title=Elle Macpherson confirms split from ex-doctor anti-vaxxer Andrew Wakefield |website=Mirror |date=9 December 2021 |url=https://www.mirror.co.uk/3am/celebrity-news/elle-macpherson-confirms-split-ex-25656038 |access-date=30 December 2021 |archive-date=27 March 2023 |archive-url=https://web.archive.org/web/20230327000029/https://www.mirror.co.uk/3am/celebrity-news/elle-macpherson-confirms-split-ex-25656038 |url-status=live }}
| occupation = Former physician, anti-vaccination activist
| known_for = Lancet MMR autism fraud
}}
{{Alternative medicine sidebar|fringe}}
Andrew Jeremy Wakefield (born 3 September 1956{{Cite book |last=Deer |first=Brian |title=The Doctor Who Fooled the World: Science, Deception, and the War on Vaccines |publisher=Johns Hopkins University Press |year=2020 |isbn=978-1-42143-800-9 |location=Baltimore, MD |pages=15–17, 61}}{{cite book |last1=Marko |first1=Vladimir |title=From Aspirin to Viagra: Stories of the Drugs that Changed the World |year=2020 |publisher=Springer Nature |isbn=978-3-030-44286-6 |page=246 |url=https://books.google.com/books?id=YbTvDwAAQBAJ&q=wakefield+1956 |access-date=12 June 2021 |archive-date=7 November 2023 |archive-url=https://web.archive.org/web/20231107064758/https://books.google.com/books?id=YbTvDwAAQBAJ&q=wakefield+1956#v=snippet&q=wakefield%201956&f=false |url-status=live }}{{efn|Some sources state 1957.{{cite news |url=http://news.bbc.co.uk/2/hi/3513365.stm |title=Profile: Dr Andrew Wakefield |website=BBC News |date=27 January 2010 |access-date=9 January 2011 |archive-date=8 February 2011 |archive-url=https://web.archive.org/web/20110208191454/http://news.bbc.co.uk/2/hi/3513365.stm |url-status=live }}}}) is a British fraudster, anti-vaccine activist, and disgraced former physician. He was struck off the medical register for "serious professional misconduct" due to his involvement in the fraudulent 1998 Lancet MMR autism study that falsely claimed a link between the measles, mumps, and rubella (MMR) vaccine and autism.
The publicity surrounding the study caused a sharp decline in vaccination uptake, leading to a number of outbreaks of measles around the world and many deaths therefrom. He was a surgeon on the liver transplant programme at the Royal Free Hospital in London, and became a senior lecturer and honorary consultant in experimental gastroenterology at the Royal Free and University College School of Medicine. He resigned from his positions there in 2001 "by mutual agreement", then moved to the United States. In 2004, Wakefield co-founded and began working at the Thoughtful House research centre (later renamed the Johnson Center for Child Health and Development) in Austin, Texas. He served as executive director of the centre until February 2010, when he resigned in the wake of findings against him by the British General Medical Council which had struck him off their register. He has subsequently become known for his anti-vaccination activism.
Wakefield published his 1998 paper on autism in the British medical journal The Lancet, claiming to have identified a novel form of enterocolitis linked to autism. However, other researchers were unable to reproduce his findings,{{cite journal |vauthors=Madsen KM, Hviid A, Vestergaard M |display-authors=etal |title=A population-based study of measles, mumps, and rubella vaccination and autism |journal=N. Engl. J. Med. |volume=347 |issue=19 |pages=1477–1482 |date=November 2002 |pmid=12421889 |doi=10.1056/NEJMoa021134|doi-access=free }}{{cite journal |vauthors=Black C, Kaye JA, Jick H |title=Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database |journal=BMJ |volume=325 |issue=7361 |pages=419–421 |date=August 2002 |pmid=12193358 |pmc=119436 |doi=10.1136/bmj.325.7361.419}} and a 2004 investigation by Sunday Times reporter Brian Deer identified undisclosed financial conflicts of interest on Wakefield's part.{{cite news |last=Deer |first=Brian |author-link=Brian Deer |title=Revealed: MMR research scandal |work=The Sunday Times |date=22 February 2004 |url=https://www.thetimes.com/uk/science/article/revealed-mmr-research-scandal-7ncfntn8mjq |access-date=16 February 2017 |location=London |url-access=subscription |archive-date=11 February 2017 |archive-url=https://web.archive.org/web/20170211195224/http://www.thetimes.co.uk/tto/health/article1879347.ece |url-status=live }} Wakefield reportedly stood to earn up to $43 million per year selling test kits. Most of Wakefield's co-authors then withdrew their support for the study's interpretations,{{cite news |first=McKee |last=Maggie |title=Controversial MMR and autism study retracted |work=New Scientist |date=4 March 2004 |url=https://www.newscientist.com/article/dn4743-controversial-mmr-and-autism-study-retracted/ |access-date=21 October 2015 |archive-url=https://web.archive.org/web/20070813055100/http://www.newscientist.com/article.ns?id=dn4743 |archive-date=13 August 2007 |url-status=dead}} and the General Medical Council (GMC) conducted an inquiry into allegations of misconduct against Wakefield and two former colleagues,{{cite news |title=MMR doctor 'to face GMC charges' |work=BBC News |date=12 June 2006 |url=http://news.bbc.co.uk/1/hi/health/5070670.stm |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070902161909/http://news.bbc.co.uk/1/hi/health/5070670.stm |archive-date=2 September 2007 |url-status=live}} focusing on Deer's findings.{{cite journal |doi=10.1136/bmj.328.7442.726-a |first=A |last=Ferriman |title=MP raises new allegations against Andrew Wakefield |journal=BMJ |volume=328 |issue=7442 |page=726 |date=March 2004 |pmid=15612092 |pmc=381348}}
In 2010, the GMC found that Wakefield had been dishonest in his research, had acted against his patients' best interests, mistreated developmentally delayed children,{{cite web |url=http://briandeer.com/solved/gmc-charge-sheet.pdf |title=General Medical Council, Fitness to Practise Panel Hearing, 28 January 2010, Andrew Wakefield, John Walker-Smith & Simon Murch |access-date=6 January 2011 |author=General Medical Council |website=BrianDeer.com |archive-url=https://web.archive.org/web/20101213133507/http://briandeer.com/solved/gmc-charge-sheet.pdf |archive-date=13 December 2010 |url-status=live}} and had "failed in his duties as a responsible consultant".{{cite news |url=http://www.yorkshireeveningpost.co.uk/news/BREAKING-MMR-expert-failed-in.6024127.jp |title=MMR-row doctor failed in his duties |work=Yorkshire Evening Post |date=28 January 2010 |access-date=28 January 2010 |archive-url=https://web.archive.org/web/20100130075415/http://www.yorkshireeveningpost.co.uk/news/BREAKING-MMR-expert-failed-in.6024127.jp |archive-date=30 January 2010 |url-status=dead}}{{cite news |url=http://news.bbc.co.uk/2/hi/health/8483865.stm |title=MMR scare doctor 'acted unethically', panel finds |work=BBC News |date=28 January 2010 |access-date=28 January 2010 |first=Nick |last=Triggle |archive-url=https://web.archive.org/web/20100128033313/http://news.bbc.co.uk/2/hi/health/8483865.stm |archive-date=28 January 2010 |url-status=live}}{{cite news |url=https://www.theguardian.com/society/2010/jan/28/andrew-wakefield-mmr-vaccine |title=Andrew Wakefield found 'irresponsible' by GMC over MMR vaccine scare |work=The Guardian |date=28 January 2010 |access-date=9 January 2011 |first=Boseley |last=Sarah |location=London |archive-url=https://web.archive.org/web/20110214200731/http://www.guardian.co.uk/society/2010/jan/28/andrew-wakefield-mmr-vaccine |archive-date=14 February 2011 |url-status=live}} The Lancet fully retracted Wakefield's 1998 publication on the basis of the GMC's findings, noting that elements of the manuscript had been falsified and that the journal had been "deceived" by Wakefield.{{cite journal |author=((The Editors of The Lancet)) |title=Retraction – Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children |journal=The Lancet |volume=375 |issue=9713 |page=445 |date=February 2010 |pmid=20137807 |doi=10.1016/S0140-6736(10)60175-4 |s2cid=26364726 |url=http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)60175-4/fulltext |access-date=19 April 2010 |archive-date=12 December 2019 |archive-url=https://web.archive.org/web/20191212071945/https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)60175-4/fulltext |url-status=live }}{{cite news |url=https://www.theguardian.com/society/2010/feb/02/lancet-retracts-mmr-paper |title=Lancet retracts 'utterly false' MMR paper |newspaper=The Guardian |date=2 February 2010 |access-date=14 January 2015 |location=London |first=Boseley |last=Sarah |archive-date=17 January 2021 |archive-url=https://web.archive.org/web/20210117232206/https://www.theguardian.com/society/2010/feb/02/lancet-retracts-mmr-paper |url-status=live }} Three months later, Wakefield was struck off the UK medical register, in part for his deliberate falsification of research published in The Lancet.{{cite web |url=http://www.gmc-uk.org/Wakefield_SPM_and_SANCTION.pdf_32595267.pdf |title=General Medical Council, Fitness to Practise Panel Hearing, 24 May 2010, Andrew Wakefield, Determination of Serious Professional Misconduct |access-date=18 September 2011 |website=General Medical Council |url-status=dead |archive-url=https://web.archive.org/web/20110809092833/http://www.gmc-uk.org/Wakefield_SPM_and_SANCTION.pdf_32595267.pdf |archive-date=9 August 2011}}{{cite news |url=https://www.theguardian.com/society/2010/may/24/mmr-doctor-andrew-wakefield-struck-off |title=MMR row doctor Andrew Wakefield struck off register |newspaper=The Guardian |date=24 May 2010 |access-date=24 May 2010 |location=London|last1=Meikle |first1=James |first2=Sarah |last2=Boseley |archive-url=https://web.archive.org/web/20100527003931/http://www.guardian.co.uk/society/2010/may/24/mmr-doctor-andrew-wakefield-struck-off |archive-date=27 May 2010 |url-status=live}} In a related legal decision, a British court held that "[t]here is now no respectable body of opinion which supports [Wakefield's] hypothesis, that MMR vaccine and autism/enterocolitis are causally linked".{{cite news |date=7 March 2012 |title=MMR doctor wins High Court appeal |work=BBC News |url=https://www.bbc.com/news/health-17283751 |access-date=23 April 2016 |archive-url=https://web.archive.org/web/20140313112850/https://www.bbc.com/news/health-17283751 |archive-date=13 March 2014 |url-status=live}}
In 2016, Wakefield directed the anti-vaccination film Vaxxed: From Cover-Up to Catastrophe.
Early life and education
Wakefield was born on 3 September 1956, to Graham Wakefield, a neurologist, and Bridget d'Estouteville Matthews, a general practitioner, at the Canadian Red Cross Memorial Hospital in Taplow, England. As a student at the independent King Edward's School, Bath, he was captain of his local rugby team.
After leaving King Edward's School,{{cite news |url=http://www.thisisbath.co.uk/news/Verdict-MMR-doctor/article-1772564-detail/article.html |title=Verdict on MMR doctor |work=Bath Chronicle |date=28 January 2010 |access-date=6 January 2011 |url-status=dead |archive-url=https://web.archive.org/web/20120426184838/http://www.thisisbath.co.uk/Verdict-MMR-doctor/story-11334990-detail/story.html |archive-date=26 April 2012}} Wakefield studied medicine at St Mary's Hospital Medical School{{cite web |first=A |last=Goddard |title=In the news: Andrew Wakefield |work=Times Higher Education Supplement |date=27 February 2004 |url=http://www.timeshighereducation.co.uk/story.asp?storyCode=183275§ioncode=26 |publisher=TSL Education Ltd. |access-date=18 February 2010 |archive-date=26 August 2012 |archive-url=https://web.archive.org/web/20120826013325/http://www.timeshighereducation.co.uk/story.asp?storyCode=183275§ioncode=26 |url-status=live }} (now Imperial College School of Medicine), fully qualifying in 1981.
Wakefield became a fellow of the Royal College of Surgeons in 1985.{{cite news |url=https://www.telegraph.co.uk/health/healthnews/7091767/Andrew-Wakefield-the-man-behind-the-MMR-controversy.html |access-date=19 February 2010 |location=London |work=The Daily Telegraph |title=Andrew Wakefield – the man behind the MMR controversy |first=Rebecca |last=Smith |date=29 January 2010 |url-status=dead |archive-url=https://archive.today/20130421080019/http://www.telegraph.co.uk/health/healthnews/7091767/Andrew-Wakefield-the-man-behind-the-MMR-controversy.html |archive-date=21 April 2013}}
Career
At the University of Toronto from 1986 to 1989, he was a member of a team that studied tissue rejection problems with small intestine transplantation, using animal models.{{cite news |url=https://www.thestar.com/news/insight/article/918362--andrew-wakefield-s-fraudulent-research |title=Andrew Wakefield's fraudulent vaccine research |first=Oakland |last=Ross |work=The Star |date=7 January 2011 |access-date=8 January 2011 |location=Toronto |archive-date=23 October 2012 |archive-url=https://web.archive.org/web/20121023064743/http://www.thestar.com/news/insight/article/918362--andrew-wakefield-s-fraudulent-research |url-status=live }}{{cite journal |doi=10.1097/00007890-198903000-00028 |first1=Richard E |last1=Silverman |first2=Zane |last2=Cohen |first3=Monica |last3=Craig |first4=Andrew |last4=Wakefield |first5=Peter |last5=Kim |first6=Bernard |last6=Langer |first7=Gary |last7=Levy |title=Monocyte/macrophage procoagulant activity as a measure of immune responsiveness in Lewis and brown Norway inbred rats. Discordance with lymphocyte proliferative assays |journal=Transplantation |volume=47 |issue=3 |pages=542–548 |date=March 1989 |pmid=2522255 |s2cid=22404063 |display-authors=3|doi-access=free }} He continued his studies of small intestine transplantation under a Wellcome Trust travelling fellowship at University of Toronto in Canada.
In the late 1980s, Wakefield{{emdash}}after returning to the UK{{emdash}}focused on research. He joined the Royal Free Hospital in London in the 1990s and remained there until his resignation in 2001. He was part of a team at the Royal working on inflammatory bowel disease from 1995 to 1998.{{Cite journal| issn = 0959-8138| volume = 328| issue = 7442| pages = 726| last = Ferriman| first = Annabel| title = MP raises new allegations against Andrew Wakefield| journal = BMJ| date = 27 March 2004| doi = 10.1136/bmj.328.7442.726-a| pmid = 15612092| pmc = 381348}}
Following his resignation from Royal Free, Wakefield moved to the United States, where he co-founded the Thoughtful House research centre in Austin, Texas. He served as the executive director of Thoughtful House, which studies autism, and continued to promote the theory of a link between the MMR vaccine and autism, despite admitting it was "not proved."
In February 2010, Wakefield resigned as the executive director of Thoughtful House after the British General Medical Council (GMC) concluded that he had engaged in unethical and dishonest conduct during his research. The GMC found that he had been "dishonest and irresponsible" in conducting his earlier autism research in England.{{cite news |work=Austin American-Statesman |title=British doctor resigns as head of Austin autism center |first=Mary Ann |last=Roser |date=18 February 2010 |access-date=1 April 2010 |url=http://www.statesman.com/news/local/british-doctor-resigns-as-head-of-austin-autism-251756.html |archive-url=https://web.archive.org/web/20100312134206/http://www.statesman.com/news/local/british-doctor-resigns-as-head-of-austin-autism-251756.html |archive-date=12 March 2010 |url-status=dead}}{{cite web |url=https://www.gmc-uk.org/-/media/documents/wakefield-determination-on-findings-of-fact-28-january-2010_pdf-35081709.pdf |title=Determination on Findings of Fact: Dr. Andrew Jeremy Wakefield |publisher=General Medical Council |date=28 January 2010 |access-date=6 February 2025}}{{cite journal |url=https://www.bmj.com/content/340/bmj.c593 |title=Wakefield was dishonest and irresponsible over MMR research, says GMC |journal=BMJ |date=29 January 2010 |first=Clare |last=Dyer |volume=340 |pages=c593 |doi=10.1136/bmj.c593 |pmid=20118180 |access-date=6 February 2025}}
The Times reported in May 2010 that he was a medical advisor for Visceral, a UK charity that "researches bowel disease and developmental disorders".
Wakefield has set up the non-profit Strategic Autism Initiative to commission studies into the condition, and in 2013 was listed as a director of a company called Medical Interventions for Autism and another called the Autism Media Channel.
Although initially supported by Donald Trump, who appeared with him in inauguration photos, the emergence of a measles epidemic led Trump to reconsider his stance.{{Cite journal| doi = 10.3399/bjgp21X714557| issn = 0960-1643| volume = 71| issue = 702| pages = 34–35| last = Lindsay| first = Peter| title = Books: long read: The Doctor Who Fooled The World. Andrew Wakefield's War On Vaccines| journal = The British Journal of General Practice| date = 1 January 2021| pmid = 33372095| pmc = 7759370}} Subsequently, social media platforms provided Wakefield with a fresh avenue to promote his anti-vaccination campaign, resulting in global repercussions, despite the fact that he has never directly treated a patient.
Wakefield directed the anti-vaccination film "Vaxxed: From Cover-Up to Catastrophe" in 2016 which was removed from the Tribeca Film Festival by one of its co-founders, Robert De Niro, whose son is on the autism spectrum.{{Cite news|url=https://www.wsj.com/articles/anti-vaccination-lunacy-wont-stop-1459721652|title=Anti-Vaccination Lunacy Won't Stop|last=Lipkin|first=W. Ian|date=3 April 2016|work=The Wall Street Journal|access-date=8 February 2019|language=en-US|issn=0099-9660}}
According to a 2020 article in The Telegraph, Wakefield had become prominent in the anti-vaccine movement and during the COVID-19 pandemic, promoted his discredited claims about vaccine safety. He appeared at summits warning that vaccines "will kill us" and called for widespread protests against their use.{{Cite news| issn = 0307-1235| title = Andrew Wakefield uses coronavirus pandemic to push discredited anti-vaccine claims| work = The Telegraph| access-date = 7 February 2025| date = 26 May 2020| url = https://www.telegraph.co.uk/news/2020/05/26/andrew-wakefield-uses-coronavirus-pandemic-push-discredited/}}
In a 2025 interview with Democracy Now, investigative journalist Brian Deer identified Robert F. Kennedy Jr., Andrew Wakefield, and Del Bigtree as the core leaders of the anti-vaccine movement. During the interview, Deer offered his perspective on the Senate confirmation hearings for Kennedy Jr., specifically addressing the questioning by senators Bernie Sanders and Bill Cassidy regarding Kennedy's alignment with Wakefield's discredited theory linking vaccines to autism.{{Cite web| last1 =Goodman |first1= Amy| last2 = Deer |first2=Brian| title = Author Slams RFK's Embrace of Disgraced Anti-Vaxxer Andrew Wakefield| work = Democracy Now!| access-date = 7 February 2025| url = https://www.democracynow.org/2025/1/31/andrew_wakefield_vaccine}}
= Claims of measles virus–Crohn's disease link =
Back in the UK, he worked on the liver transplant programme at the Royal Free Hospital in London. In 1993, Wakefield attracted professional attention when he published reports in which he concluded that measles virus might cause Crohn's disease;{{cite journal |vauthors=Wakefield AJ, Pittilo RM, Sim R |display-authors=etal |title=Evidence of persistent measles virus infection in Crohn's disease |journal=J. Med. Virol. |volume=39 |issue=4 |pages=345–353 |date=April 1993 |pmid=8492105 |doi=10.1002/jmv.1890390415 |s2cid=29899812}} and two years later he published a paper in The Lancet proposing a link between the measles vaccine and Crohn's disease.{{cite journal |vauthors=Thompson NP, Montgomery SM, Pounder RE, Wakefield AJ |title=Is measles vaccination a risk factor for inflammatory bowel disease? |journal=Lancet |volume=345 |issue=8957 |pages=1071–1074 |date=April 1995 |pmid=7715338 |doi=10.1016/s0140-6736(95)90816-1 |s2cid=30683685}} Subsequent research failed to confirm this hypothesis, with a group of experts in Britain reviewing a number of peer-reviewed studies in 1998 and concluding that the measles virus did not cause Crohn's disease, and neither did the MMR vaccine.{{cite web |url=http://www.slate.com/articles/health_and_science/medical_examiner/2010/06/wakefields_first_try.2.html |title=Wakefield's First Try |work=Slate |date=2 June 2010 |access-date=27 December 2013 |first=Nayanah |last=Siva |archive-date=28 December 2013 |archive-url=https://web.archive.org/web/20131228065514/http://www.slate.com/articles/health_and_science/medical_examiner/2010/06/wakefields_first_try.2.html |url-status=live }}
Later, in 1995, while conducting research into Crohn's disease, he was approached by Rosemary Kessick, the parent of a child with autism, who was seeking help with her son's bowel problems and autism; Kessick ran a group called Allergy Induced Autism.{{cite news |first=Grania |last=Langdon-Down |title=Law: A Shot in the Dark |page=25 |work=The Independent |date=27 November 1996 |url=http://briandeer.com/wakefield/dawbarns-kessick.htm |via=BrianDeer.com |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070810044020/http://briandeer.com/wakefield/dawbarns-kessick.htm |archive-date=10 August 2007 |url-status=live}} In 1996, Wakefield turned his attention to researching possible connections between the MMR vaccine and autism.
At the time of his MMR research study, Wakefield was senior lecturer and honorary consultant in experimental gastroenterology at the Royal Free Hospital School of Medicine (from 2008, UCL Medical School). He resigned in 2001, by "mutual agreement and was made a fellow of the Royal College of Pathologists", and moved to the US in 2001{{cite news |url=http://www.timesonline.co.uk/tol/news/uk/article7134893.ece |date=25 May 2010 |title=Dr Andrew Wakefield struck off medical register |last1=Sanchez |first1=Raf |last2=Rose |first2=David |work=The Times |location=London |archive-url=https://web.archive.org/web/20100601070035/http://www.timesonline.co.uk/tol/news/uk/article7134893.ece |archive-date=1 June 2010}} (or 2004, by another account).{{cite news |title=Profile: Andrew Wakefield, the man at the centre of the MMR scare |url=https://www.thetimes.com/article/profile-andrew-wakefield-the-man-at-the-centre-of-the-mmr-scare-fn6ft7s5wqn |date=24 May 2010 |access-date=9 January 2011 |work=The Times |location=London|archive-date=16 May 2021 |archive-url=https://web.archive.org/web/20210516205342/https://www.thetimes.co.uk/article/profile-andrew-wakefield-the-man-at-the-centre-of-the-mmr-scare-fn6ft7s5wqn |url-status=live }} He was reportedly asked to leave the Royal Free Hospital after refusing a request to validate his 1998 Lancet paper with a controlled study.
Wakefield is barred from practising as a physician in the UK, and is not licensed in the US.{{cite news |url=http://www.timesonline.co.uk/tol/life_and_style/health/article5728998.ece |title=MMR scare doctor Andrew Wakefield makes fortune in US |work=The Times |date=14 February 2009 |last1=Bone |first1=James |last2=Rose |first2=David |location=London |url-status=dead |archive-url=https://web.archive.org/web/20100602022723/http://www.timesonline.co.uk/tol/life_and_style/health/article5728998.ece |archive-date=2 June 2010}} He lives in the US where he has a following, including the anti-vaccinationist Jenny McCarthy, who wrote the foreword for Wakefield's autobiography, Callous Disregard. She has a son with autism-like symptoms that she believes were caused by the MMR vaccine.{{cite news |url=https://healthland.time.com/2011/01/06/study-linking-vaccines-to-autism-is-fraudulent/ |title=Study linking vaccines to autism is 'fraudulent' |first=Alice |last=Park |magazine=Time |date=6 January 2011 |access-date=7 January 2011 |archive-url=https://web.archive.org/web/20110113042913/http://healthland.time.com/2011/01/06/study-linking-vaccines-to-autism-is-fraudulent/ |archive-date=13 January 2011 |url-status=live}} According to Deer, {{as of|2011|lc=y}}, Wakefield lives near Austin with his family.{{cite news |url=https://www.theguardian.com/society/2013/apr/06/what-happened-man-mmr-panic |title=Andrew Wakefield: Autism Inc. |first=Alex |last=Hannaford |work=The Guardian |date=6 April 2013 |access-date=13 September 2013 |archive-date=1 February 2017 |archive-url=https://web.archive.org/web/20170201201709/https://www.theguardian.com/society/2013/apr/06/what-happened-man-mmr-panic |url-status=live }}
''The Lancet'' fraud
{{Further|Lancet MMR autism fraud}}
On 28 February 1998, Wakefield was the lead author of a study of twelve children with autism that was published in The Lancet. The study proposed a new syndrome called autistic enterocolitis, and raised the possibility of a link between a novel form of bowel disease, autism, and the MMR vaccine. The authors said that the parents of eight of the twelve children linked what were described as "behavioural symptoms" with MMR, and reported that the onset of these symptoms began within two weeks of MMR vaccination.
These possible triggers were reported as MMR in eight cases, and measles infection in one. The paper was instantly controversial, leading to widespread publicity in the UK and the convening of a special panel of the UK's Medical Research Council the following month.{{cite web |title=Wakefield misled experts over children |last=Deer |first=Brian |date=23 March 1998 |url=http://briandeer.com/mmr/wakefield-mrc.htm |access-date=10 August 2007 |website=BrianDeer.com |archive-url=https://web.archive.org/web/20070810191050/http://briandeer.com/mmr/wakefield-mrc.htm |archive-date=10 August 2007 |url-status=live}} One 2005 study in Japan found that there was no causal relationship between the MMR vaccine and autism in groups of children given the triple MMR vaccine and children who received individual measles, mumps and rubella vaccinations. In Japan, the MMR vaccine had been replaced with individual vaccinations in 1993.{{cite journal |vauthors=Honda H, Shimizu Y, Rutter M |journal=J Child Psychol Psychiatry |volume=46 |issue=6 |pages=572–529 |year=2005 |pmid=15877763 |doi=10.1111/j.1469-7610.2005.01425.x |title=No effect of MMR withdrawal on the incidence of autism: a total population study |doi-access=free}}
Although the paper said that no causal connection had been proven, before it was published, Wakefield made statements at a press conference and in a video news release issued by the hospital, calling for suspension of the triple MMR vaccine until more research could be done.{{cite web |title=Royal Free MMR video news release, 1998 |last=Deer |first=Brian |date=4 February 1998 |url=http://briandeer.com/wakefield/royal-video.htm |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070711055354/http://briandeer.com/wakefield/royal-video.htm |archive-date=11 July 2007 |url-status=live}} This was later criticized as 'science by press conference'.{{cite journal |first=Andrew |last=Moore |year=2006 |title=Bad science in the headlines: Who takes responsibility when science is distorted in the mass media? |journal=EMBO Reports |volume=7 |issue=12 |pages=1193–1196 |doi=10.1038/sj.embor.7400862 |pmid=17139292 |pmc=1794697}} According to BBC News, it was this press conference, rather than the paper in The Lancet, that fuelled the MMR vaccination scare. The BBC report said he told journalists: "it was a 'moral issue' and he could no longer support the continued use of the three-in-one jab for measles, mumps and rubella. 'Urgent further research is needed to determine whether MMR may give rise to this complication in a small number of people,' Wakefield said at the time."{{cite news |url=http://news.bbc.co.uk/2/hi/health/8481583.stm |date=28 January 2010 |title=Wakefield and autism: the story that will not go away |work=BBC News |first=Nick |last=Triggle |access-date=9 January 2011 |archive-url=https://web.archive.org/web/20110203172245/http://news.bbc.co.uk/2/hi/health/8481583.stm |archive-date=3 February 2011 |url-status=live}} He said, "If you give three viruses together, three live viruses, then you potentially increase the risk of an adverse event occurring, particularly when one of those viruses influences the immune system in the way that measles does." He suggested parents should opt for single vaccinations against measles, mumps and rubella, separated by gaps of one year. 60 Minutes interviewed him in November 2000, and he repeated these claims to the U.S. audience, providing a new focus for the nascent anti-vaccination movement in the U.S., which had been primarily concerned about thiomersal in vaccines.{{cite journal |last1=Offit |first1=PA |last2=Coffin |first2=SE |title=Communicating science to the public: MMR vaccine and autism |journal=Vaccine |volume=22 |issue=1 |pages=1–6 |pmid=14604564 |year=2003 |doi=10.1016/s0264-410x(03)00532-2}}{{cite news |last1=Chu |first1=Henry |title=British doctor rebuked over research linking vaccine and autism |url=https://www.latimes.com/archives/la-xpm-2010-jan-29-la-fg-britain-autism29-2010jan29-story.html |work=Los Angeles Times |date=29 January 2010 |access-date=26 October 2017 |archive-date=22 March 2017 |archive-url=https://web.archive.org/web/20170322153900/http://articles.latimes.com/2010/jan/29/world/la-fg-britain-autism29-2010jan29 |url-status=live }}
In November 2001, Wakefield resigned from the Royal Free Hospital,{{cite journal |last1=Ramsay |first1=Sarah |title=Controversial MMR-autism investigator resigns from research post |journal=The Lancet |date=2001 |volume=358 |issue=9297 |page=1972 |doi=10.1016/S0140-6736(01)07007-6 |url=https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(01)07007-6/abstract |issn=1474-547X}} saying, "I have been asked to go because my research results are unpopular."{{cite news |first=Lorraine |last=Fraser |title=Anti-MMR doctor is forced out |url=https://www.telegraph.co.uk/news/uknews/1364080/Anti-MMR-doctor-is-forced-out.html |work=The Daily Telegraph |date=2 December 2001 |access-date=29 March 2009 |location=London |archive-date=8 March 2019 |archive-url=https://web.archive.org/web/20190308003020/https://www.telegraph.co.uk/news/uknews/1364080/Anti-MMR-doctor-is-forced-out.html |url-status=live }} The medical school said that he had left "by mutual agreement". In February 2002, Wakefield stated: "What precipitated this crisis was the removal of the single vaccine, the removal of choice, and that is what has caused the furore—because the doctors, the gurus, are treating the public as though they are some kind of moronic mass who cannot make an informed decision for themselves."{{cite news |first=Andrew |last=Wakefield |title=Why I owe it to parents to question triple vaccine |work=Sunday Herald |date=10 February 2002 |url=http://www.sundayherald.com/22194 |archive-url=https://web.archive.org/web/20030803151022/http://www.sundayherald.com/22194 |archive-date=3 August 2003 |access-date=10 August 2007}}
= Aftermath of initial controversy =
Wakefield continued to conduct clinical research in the United States after leaving the Royal Free Hospital in December 2001. He joined a controversial American researcher, Jeff Bradstreet, at the International Child Development Resource Center, to conduct further studies on the possible relationship between the MMR vaccine and autism.{{cite web |url=http://briandeer.com/wakefield/wakefield-quack.htm |title=Wakefield joins strange enterprise after 'transfer factor' autism products fail |last=Deer |first=Brian |website=BrianDeer.com |access-date=1 April 2010 |archive-url=https://web.archive.org/web/20100505184934/http://briandeer.com/wakefield/wakefield-quack.htm |archive-date=5 May 2010 |url-status=dead }}
In 2004, Wakefield began working at the Thoughtful House research centre in Austin, Texas.{{cite news |url=https://www.thetimes.com/article/mmr-row-doctor-andrew-wakefield-spreads-fear-to-us-bzq0kd7gz35 |title=MMR row doctor Andrew Wakefield spreads fear to US |work=The Times |location=London |date=28 September 2008 |access-date=25 April 2010 |first=John |last=Harlow |archive-date=16 May 2021 |archive-url=https://web.archive.org/web/20210516205342/https://www.thetimes.co.uk/article/mmr-row-doctor-andrew-wakefield-spreads-fear-to-us-bzq0kd7gz35 |url-status=live }} Wakefield served as executive director of Thoughtful House until February 2010, when he resigned in the wake of findings against him by the British General Medical Council.{{cite news |url=https://www.theguardian.com/society/2010/feb/19/wakefield-quits-texas-autism-centre |title=MMR vaccine doctor Andrew Wakefield quits autism centre |work=The Guardian |date=19 February 2010 |location=London |first=Aidan |last=Jones |access-date=25 April 2010 |archive-url=https://web.archive.org/web/20100407154235/http://www.guardian.co.uk/society/2010/feb/19/wakefield-quits-texas-autism-centre |archive-date=7 April 2010 |url-status=live}}
In February 2004, the controversy resurfaced when Wakefield was accused of a conflict of interest. In The Sunday Times, Brian Deer reported that some of the parents of the 12 children in the study in The Lancet were recruited via a UK lawyer preparing a lawsuit against MMR manufacturers, and that the Royal Free Hospital had received £55,000 from the UK's Legal Aid Board (now the Legal Services Commission) to pay for the research.{{cite news |last=Deer |first=Brian |title=Revealed: MMR Research Scandal |work=The Sunday Times |via=BrianDeer.com |date=22 February 2004 |url=http://briandeer.com/mmr/lancet-deer-1.htm |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070808103704/http://briandeer.com/mmr/lancet-deer-1.htm |archive-date=8 August 2007 |url-status=live}} Previously, in October 2003, the board had cut off public funding for the litigation against MMR manufacturers.{{cite web |title=Taxpayer cash for MMR action is stopped after £15m that stoked fear was spent |last=Deer |first=Brian |website=BrianDeer.com |url=http://briandeer.com/mmr/lancet-lsc.htm |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070810191523/http://briandeer.com/mmr/lancet-lsc.htm |archive-date=10 August 2007 |url-status=live}} Following an investigation of the allegations in The Sunday Times by the UK General Medical Council, Wakefield was charged with serious professional misconduct, including dishonesty.{{cite news |last=Deer |first=Brian |title=MMR Scare Doctor Faces List of Charges |work=The Sunday Times |location=London |date=11 September 2005 |url=https://www.thetimes.com/best-law-firms/profile-legal/article/mmr-scare-doctor-faces-list-of-charges-5t3td2097j6 |access-date=29 March 2009 |archive-date=26 October 2021 |archive-url=https://web.archive.org/web/20211026114806/https://www.thetimes.co.uk/article/mmr-scare-doctor-faces-list-of-charges-5t3td2097j6 |url-status=live }} In December 2006, Deer, writing in The Sunday Times, further reported that in addition to the money they donated to the Royal Free Hospital, the lawyers responsible for the MMR lawsuit had paid Wakefield personally more than £400,000, which he had not previously disclosed.{{cite news |last=Deer |first=Brian |title=MMR doctor given legal aid thousands |work=The Times |date=31 December 2006 |url=http://briandeer.com/mmr/st-dec-2006.htm |access-date=10 August 2007 |location=London, UK |via=BrianDeer.com |archive-date=2 April 2019 |archive-url=https://web.archive.org/web/20190402104910/https://briandeer.com/mmr/st-dec-2006.htm |url-status=live }}
Twenty-four hours before the 2004 Sunday Times report by Deer, The Lancet{{'}}s editor Richard Horton responded to the investigation in a public statement, describing Wakefield's research as "fatally flawed" and said he believed the paper would have been rejected as biased if the peer reviewers had been aware of Wakefield's conflict of interest.{{cite news |title=Lead researcher defends MMR study |work=BBC News |date=22 February 2004 |url=http://news.bbc.co.uk/1/hi/health/3510721.stm |access-date=10 August 2007 |archive-date=18 February 2007 |archive-url=https://web.archive.org/web/20070218062448/http://news.bbc.co.uk/1/hi/health/3510721.stm |url-status=live }} Ten of Wakefield's twelve co-authors of the paper in The Lancet later published a retraction of an interpretation.{{cite journal |last1=Murch |first1=SH |last2=Anthony |first2=A |last3=Casson |first3=DH |last4=Malik |first4=M |last5=Berelowitz |first5=M |last6=Dhillon |first6=AP |last7=Thomson |first7=MA |last8=Valentine |first8=A |last9=Davies |first9=SE |title=Retraction of an interpretation |journal=The Lancet |volume=363 |issue=9411 |page=750 |year=2004 |pmid=15016483 |doi=10.1016/S0140-6736(04)15715-2 |s2cid=5128036 |display-authors=3}} The section of the paper retracted read as follows:
{{blockquote|1=Interpretation. We identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.}}
{{blockquote|1=We wish to make it clear that in this paper no causal link was established between (the) vaccine and autism, as the data were insufficient. However the possibility of such a link was raised, and consequent events have had major implications for public health. In view of this, we consider now is the appropriate time that we should together formally retract the interpretation placed upon these findings in the paper, according to precedent.{{cite news |first=Emma |last=Ross |title=Scientists retract interpretation of research linking vaccine with autism |agency=Associated Press |website=BrianDeer.com |date=3 March 2004 |url=http://briandeer.com/mmr/lancet-retraction.htm |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070811220948/http://briandeer.com/mmr/lancet-retraction.htm |archive-date=11 August 2007 |url-status=live}}}}
= ''Wakefield v Channel 4 Television and Others'' =
In November 2004, Channel 4 broadcast a one-hour Dispatches investigation by reporter Brian Deer; the Toronto Star said Deer had "produced documentary evidence that Wakefield applied for a patent on a single-jab measles vaccine before his campaign against the MMR vaccine, raising questions about his motives".{{cite web |title=Revealed: the first Wakefield MMR patent claim describes "safer measles vaccine" |last=Deer |first=Brian |url=http://briandeer.com/wakefield/vaccine-patent.htm |website=BrianDeer.com |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070809105007/http://briandeer.com/wakefield/vaccine-patent.htm |archive-date=9 August 2007 |url-status=live}}{{cite web |url=http://www.freepatentsonline.com/6534259.pdf |title=US6534259: Regressive behavioral disorder diagnosis |date=18 March 2003 |website=Freepatentsonline.com |access-date=14 January 2011 |archive-date=25 September 2018 |archive-url=https://web.archive.org/web/20180925025517/http://www.freepatentsonline.com/6534259.pdf |url-status=live }}
In addition to Wakefield's unpublished initial patent submission, Deer released a copy of the published patent application.{{cite web |title=UK Patent Application GB 2 325 856 A |url=http://briandeer.com/mmr/1998-vaccine-patent.pdf |archive-url=https://web.archive.org/web/20100524175841/http://briandeer.com/mmr/1998-vaccine-patent.pdf |archive-date=24 May 2010 |website=BrianDeer.com}} At page 1, the first paragraph of this stated:
{{blockquote|1=The present invention relates to a new vaccine/immunisation for the prevention and/or prophylaxis against measles virus infection and to a pharmaceutical or therapeutic composition for the treatment of IBD (Inflammatory Bowel Disease); particularly Crohn's Disease and Ulcerative Colitis and regressive behavioural disease (RBD).}}
Before describing the research in Wakefield's 1998 paper in The Lancet, at the same page this patent explicitly states that the use of the MMR vaccine causes autism:
{{blockquote|1=It has now also been shown that use of the MMR vaccine (which is taken to include live attenuated measles vaccine virus, measles virus, mumps vaccine virus and rubella vaccine virus, and wild strains of the aforementioned viruses) results in ileal lymphoid nodular hyperplasia, chronic colitis and pervasive developmental disorder including autism (RBD), in some infants.}}
According to Deer, a letter from Wakefield's lawyers to him dated 31 January 2005 said: "Dr Wakefield did not plan a rival vaccine."
In the Dispatches programme, Deer also revealed that Nicholas Chadwick, a researcher working under Wakefield's supervision in the Royal Free medical school, had failed to find measles virus in the children reported on in The Lancet.{{cite web |last=Deer |first=Brian |title=Molecular testing in Wakefield's own lab rebutted the basis for his attack on MMR |url=http://briandeer.com/wakefield/nick-chadwick.htm |website=BrianDeer.com |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070809174125/http://briandeer.com/wakefield/nick-chadwick.htm |archive-date=9 August 2007 |url-status=live}}
In January 2005, Wakefield initiated libel proceedings against Channel 4, the independent production company Twenty Twenty and Brian Deer, The Sunday Times, and against Deer personally along with his website briandeer.com{{cite web |url=http://briandeer.com/ |title=Selected Investigations & Journalism |website=BrianDeer.com |date=31 January 2011 |access-date=26 April 2013 |archive-date=30 April 2013 |archive-url=https://web.archive.org/web/20130430035834/http://briandeer.com/ |url-status=live }} in the case Wakefield v Channel Four Television and Others [2006] EWHC 3289 (QB); [2007] 94 BMLR 1. Within weeks of issuing his claims, however, Wakefield sought to have the action frozen until after the conclusion of General Medical Council proceedings against him. Channel 4 and Deer sought a High Court order compelling Wakefield to continue with his action, or discontinue it. After a hearing on 27 and 28 October 2005, Justice David Eady ruled against a stay of proceedings:
{{blockquote|1=It thus appears that the Claimant wishes to use the existence of the libel proceedings for public relations purposes, and to deter other critics, while at the same time isolating himself from the "downside" of such litigation, in having to answer a substantial defence of justification ... I am quite satisfied, therefore, that the Claimant wished to extract whatever advantage he could from the existence of the proceedings while not wishing to progress them or to give the Defendants an opportunity of meeting the claims.{{cite web |title=Approved Judgment in the case of Andrew Wakefield vs. Channel Four Television Corporation, Twenty Twenty Productions Ltd., and Brian Deer |website=British and Irish Legal Information Institute |date=4 November 2005 |url=http://www.bailii.org/ew/cases/EWHC/QB/2005/2410.html |access-date=10 August 2007 |archive-date=25 January 2016 |archive-url=https://web.archive.org/web/20160125205001/http://www.bailii.org/ew/cases/EWHC/QB/2005/2410.html |url-status=live }}}}
The judgment identified Channel 4's "very lengthy extracts" summarizing Deer's allegations against Wakefield:
:(i) [Wakefield] spread fear that the MMR vaccine might lead to autism, even though he knew that his own laboratory had carried out tests whose results dramatically contradicted his claims in that the measles virus had not been found in a single one of the children concerned in his study and he knew or ought to have known that there was absolutely no basis at all for his belief that the MMR should be broken up into single vaccines.
:(ii) In spreading such fear, acted dishonestly and for mercenary motives in that, although he improperly failed to disclose the fact, he planned a rival vaccine and products (such as a diagnostic kit based on his theory) that could have made his fortune
:(iii) Gravely abused the children under his care by unethically carrying out extensive invasive procedures (on occasions requiring three people to hold a child down), thereby driving nurses to leave and causing his medical colleagues serious concern and unhappiness
:(iv) Improperly and/or dishonestly failed to disclose to his colleagues and to the public that his research on autistic children had begun with a contract with solicitors who were trying to sue the manufacturers of the MMR vaccine
:(v) Improperly or dishonestly lent his reputation to the International Child Development Resource Centre, which promoted to very vulnerable parents expensive products for whose efficacy (as he knew or should have known) there was no scientific evidence
Eady's ruling states that, "The views or conclusions of the GMC disciplinary body would not, so far as I can tell, be relevant or admissible", that Channel 4's allegations "go to undermine fundamentally the Claimant's professional integrity and honesty", and that, "It cannot seriously be suggested that priority should be given to GMC proceedings for the resolution of issues."
In December 2006, Deer released records obtained from the Legal Services Commission, showing that it had paid £435,643 in undisclosed fees to Wakefield for the purpose of building a case against the MMR vaccine.{{cite web |title=Revealed: undisclosed payments to Andrew Wakefield at the heart of vaccine alarm |last=Deer |first=Brian |url=http://briandeer.com/wakefield/legal-aid.htm |website=BrianDeer.com |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070821211233/http://briandeer.com/wakefield/legal-aid.htm |archive-date=21 August 2007 |url-status=live}} Those payments, The Sunday Times reported, had begun two years before publication of Wakefield's paper in The Lancet. Within days of Deer's report, Wakefield dropped all his libel actions{{cite web |url=https://briandeer.com/wakefield/lawsuit-discontinues.htm |title=Wakefield drops libel claim over Channel 4 investigation, and agrees to pay costs |access-date=21 October 2009 |last=Deer |first=Brian |website=BrianDeer.com |archive-url=https://web.archive.org/web/20091114154127/http://briandeer.com/wakefield/lawsuit-discontinues.htm |archive-date=14 November 2009 |url-status=dead }} and was ordered to pay all defendants' legal costs.{{cite news |url=http://www.pressgazette.co.uk/node/36663 |title=MMR Doc drops libel case versus Channel Four |work=Press Gazette |date=26 January 2007 |access-date=6 January 2011 |archive-url=https://web.archive.org/web/20130524205844/http://www.pressgazette.co.uk/node/36663 |archive-date=24 May 2013 |url-status=dead }}{{cite journal |first=Clare |last=Dyer |title=Andrew Wakefield drops libel case against Channel 4 |journal=BMJ |volume=334 |issue=7584 |page=60 |date=January 2007 |pmid=17218681 |pmc=1767245 |doi=10.1136/bmj.39090.395509.DB}}
= Other concerns =
Wakefield's data was also questioned; a former graduate student, who appeared in Deer's programme, later testified that Wakefield ignored laboratory data that conflicted with his hypothesis. An independent investigation of a collaborating laboratory questioned the accuracy of the data underpinning Wakefield's claims.{{cite news |work=Newsweek |title=Anatomy of a Scare |date=21 February 2009 |access-date=28 January 2010 |first=Sharon |last=Begley |url=http://www.newsweek.com/id/185853/page/1 |archive-url=https://web.archive.org/web/20100208135234/http://www.newsweek.com/id/185853/page/1 |archive-date=8 February 2010 |url-status=live}}
In June 2005, the BBC programme Horizon reported on an unnamed and unpublished study of blood samples from a group of 100 autistic children and 200 children without autism. They reported finding 99% of the samples contained no trace of the measles virus, and the samples that did contain the virus were just as likely to be from non-autistic children, i.e., only three samples contained the measles virus, one from an autistic child and two from a typically developing child. The study's authors found no evidence of any link between MMR and autism.{{cite news |title=Does the MMR Jab Cause Autism? The latest scientific evidence |website=BBC Horizon |url=http://www.bbc.co.uk/sn/tvradio/programmes/horizon/mmr_prog_summary.shtml |access-date=10 August 2007 |archive-date=13 January 2020 |archive-url=https://web.archive.org/web/20200113093623/http://www.bbc.co.uk/sn/tvradio/programmes/horizon/mmr_prog_summary.shtml |url-status=live }}
The Institute of Medicine (IOM) of the United States National Academy of Sciences,{{cite book |author=Immunization Safety Review Committee |title=Immunization Safety Review: Vaccines and Autism |year=2004 |publisher=Institute of Medicine |access-date=10 August 2007 |url=http://www.iom.edu/reports/2004/immunization-safety-review-vaccines-and-autism.aspx |isbn=978-0-309-53275-4 |url-status=dead |archive-url=https://web.archive.org/web/20091026043205/http://www.iom.edu/reports/2004/immunization-safety-review-vaccines-and-autism.aspx |archive-date=26 October 2009}} along with the CDC{{cite web |url=https://www.cdc.gov/vaccinesafety/Vaccines/MMR/MMR.html |title=Measles, mumps, and rubella (MMR) vaccine |date=15 May 2010 |access-date=8 January 2011 |website=Centers for Disease Control and Prevention |archive-date=5 March 2019 |archive-url=https://web.archive.org/web/20190305184231/https://www.cdc.gov/vaccinesafety/vaccines/mmr/mmr.html |url-status=live }} and the UK National Health Service,{{cite web |year=2009 |title=MMR – FAQs |url=http://www.nhs.uk/Conditions/MMR/Pages/FAQs.aspx#autismrisk |archive-url=https://web.archive.org/web/20100524000405/http://www.nhs.uk/Conditions/MMR/Pages/FAQs.aspx#autismrisk |archive-date=24 May 2010 |access-date=8 January 2011 |website=National Health Service}} have found no link between vaccines and autism. Reviews in the medical literature have also found no link between the MMR vaccine and autism or with bowel disease, which Wakefield called "autistic enterocolitis".{{cite journal |vauthors=Jefferson T, Price D, Demicheli V, Bianco E |title=Unintended events following immunization with MMR: a systematic review |journal=Vaccine |year=2003 |pages=3954–3960 |volume=21 |issue=25–26 |pmid=12922131 |doi=10.1016/S0264-410X(03)00271-8}}{{cite journal |vauthors=Gerber JS, Offit PA |title=Vaccines and Autism: A Tale of Shifting Hypotheses |journal=Clin. Infect. Dis. |volume=48 |issue=4 |pages=456–461 |year=2009 |pmid=19128068 |pmc=2908388 |doi=10.1086/596476 |url=http://www.csicop.org/si/show/more_studies_reject_vaccine-autism_link/ |access-date=30 January 2009 |archive-date=11 March 2014 |archive-url=https://web.archive.org/web/20140311235949/http://www.csicop.org/si/show/more_studies_reject_vaccine-autism_link/ |url-status=dead }}{{Cite journal |last1=Di Pietrantonj |first1=Carlo |last2=Rivetti |first2=Alessandro |last3=Marchione |first3=Pasquale |last4=Debalini |first4=Maria Grazia |last5=Demicheli |first5=Vittorio |date=20 April 2020 |title=Vaccines for measles, mumps, rubella, and varicella in children |journal=The Cochrane Database of Systematic Reviews |volume=4 |issue=4 |pages=CD004407 |doi=10.1002/14651858.CD004407.pub4 |issn=1469-493X |pmc=7169657 |pmid=32309885}}
General Medical Council hearings
Between July 2007 and May 2010, a 217-day "fitness to practise" hearing of the UK General Medical Council examined charges of professional misconduct against Wakefield and two colleagues involved in the paper in The Lancet.{{cite news |title=MMR scare doctor 'paid children' |work=BBC News |date=16 July 2007 |url=http://news.bbc.co.uk/2/hi/health/6289166.stm |access-date=10 August 2007 |archive-url=https://web.archive.org/web/20070818102609/http://news.bbc.co.uk/1/hi/health/6289166.stm |archive-date=18 August 2007 |url-status=live}}{{cite press release |author=General Medical Council |title=Dr Andrew Wakefield, Professor John Walker-Smith, Professor Simon Murch: Fitness to Practise Hearings |publisher=General Medical Council Press Office |date=8 October 2007 |url=http://www.gmcpressoffice.org.uk/apps/news/events/detail.php?key=1970 |archive-url=https://web.archive.org/web/20071027142725/http://www.gmcpressoffice.org.uk/apps/news/events/detail.php?key=1970 |archive-date=27 October 2007}} The charges included that he:
- "Was being paid to conduct the study by solicitors representing parents who believed their children had been harmed by MMR".
- Ordered investigations "without the requisite paediatric qualifications" including colonoscopies, colon biopsies and lumbar punctures ("spinal taps") on his research subjects without the approval of his department's ethics board and contrary to the children's clinical interests, when these diagnostic tests were not indicated by the children's symptoms or medical history.
- "Act[ed] 'dishonestly and irresponsibly' in failing to disclose ... how patients were recruited for the study" as well as in his descriptions in the Lancet papers and in questions after the paper published, about what ailments the children had, and when those ailments were observed relative to their getting vaccinated.{{cite journal |last1=Randi |first1=James |author-link1=James Randi |title=The Dangerous Delusion about Vaccines and Autism |journal=Skeptical Inquirer |date=2017 |volume=41 |issue=2 |pages=29–31 |url=https://www.csicop.org/si/show/the_dangerous_delusion_about_vaccines_and_autism |archive-url=https://web.archive.org/web/20181028153812/https://www.csicop.org/si/show/the_dangerous_delusion_about_vaccines_and_autism |url-status=dead |archive-date=28 October 2018}}{{cite web |title=Fitness to Practice Panel Hearing |url=https://www.nhs.uk/news/2010/01January/Documents/FACTS%20WWSM%20280110%20final%20complete%20corrected.pdf |author=General Medical Council |website=NHS |date=28 January 2010 |url-status=dead |archive-url=https://web.archive.org/web/20111122155324/https://www.nhs.uk/news/2010/01January/Documents/FACTS%20WWSM%20280110%20final%20complete%20corrected.pdf |archive-date=22 November 2011}}{{rp|Para. 33–36, pp 45–48}}
- "Conduct[ed] the study on a basis not approved by the hospital's ethics committee."
- Purchased blood samples—for £5 each—from children present at his son's birthday party, which Wakefield joked about in a later presentation.
- "[S]howed callous disregard for any distress or pain the children might suffer"
Wakefield denied the charges;{{cite news |work=BBC News |url=http://news.bbc.co.uk/1/hi/health/7314144.stm |title=MMR doctor to begin his defence |date=27 March 2008 |access-date=5 January 2011 |archive-date=13 February 2009 |archive-url=https://web.archive.org/web/20090213235931/http://news.bbc.co.uk/1/hi/health/7314144.stm |url-status=live }} on 28 January 2010, the GMC ruled against Wakefield on all issues, stating that he had "failed in his duties as a responsible consultant", acted against the interests of his patients, and "dishonestly and irresponsibly" in his controversial research. On 24 May 2010, he was struck off the United Kingdom medical register. It was the harshest sanction that the GMC could impose, and effectively ended his career as a physician. In announcing the ruling, the GMC said that Wakefield had "brought the medical profession into disrepute", and no sanction short of erasing his name from the register was appropriate for the "serious and wide-ranging findings" of misconduct.{{cite news |url=http://news.bbc.co.uk/1/hi/health/8695267.stm |title=MMR doctor struck off register |first=Nick |last=Triggle |date=24 May 2010 |website=BBC News |access-date=24 May 2010 |archive-url=https://web.archive.org/web/20100526020901/http://news.bbc.co.uk/1/hi/health/8695267.stm |archive-date=26 May 2010 |url-status=live}} On the same day, Wakefield's autobiography, Callous Disregard was published, using the same words as one of the charges against him ("he showed callous disregard for any distress or pain the children might suffer"). Wakefield argued that he had been unfairly treated by the medical and scientific establishment.{{cite book |title=Callous Disregard |first=Andrew J |last=Wakefield |isbn=978-1-61608-169-0 |publisher=Skyhorse Publishing |date=2010 |url=https://archive.org/details/callousdisregard00wake}}
Fraud and conflict of interest allegations
In February 2009, The Sunday Times reported that a further investigation by the newspaper had revealed that Wakefield "changed and misreported results in his research, creating the appearance of a possible link with autism",{{cite news |url=http://www.timesonline.co.uk/tol/life_and_style/health/article5683671.ece |title=MMR doctor Andrew Wakefield fixed data on autism |last=Deer |first=Brian |work=The Sunday Times |date=8 February 2009 |access-date=9 February 2009 |location=London |archive-url=https://web.archive.org/web/20100525134829/http://www.timesonline.co.uk/tol/life_and_style/health/article5683671.ece |archive-date=25 May 2010 |url-status=dead}} citing evidence obtained by the newspaper from medical records and interviews with witnesses, and supported by evidence presented to the GMC.
In April 2010, Deer expanded on laboratory aspects of his findings in a report in the BMJ, recounting how normal clinical histopathology results (obtained from the Royal Free hospital) had been subjected to wholesale changes, from normal to abnormal, in the medical school and published in The Lancet.{{cite journal |last=Deer |first=Brian |title=Wakefield's "autistic enterocolitis" under the microscope |journal=BMJ |volume=340 |page=c1127 |date=15 April 2010 |pmid=20395277 |doi=10.1136/bmj.c1127 |s2cid=31808411 |url=http://www.bmj.com/content/340/bmj.c1127.long |doi-access= |access-date=6 January 2011 |archive-date=7 February 2019 |archive-url=https://web.archive.org/web/20190207062640/https://www.bmj.com/content/340/bmj.c1127.long |url-status=live }} On 2 January 2011, Deer provided two tables comparing the data on the twelve children, showing the original hospital data and the data with the wholesale changes as used in the 1998 The Lancet article.{{cite web |url=https://www.bmj.com/content/bmj/suppl/2011/01/05/bmj.c5347.DC1/deeb200710.ww1_default.pdf |title=MMR & Autism: Fixing a Link (Tables prepared by Brian Deer as a supplement to his peer reviewed report "How the case against the MMR vaccine was fixed") |first=Brian |last=Deer |date=January 2011 |website=BMJ |access-date=16 May 2021 |archive-date=29 March 2023 |archive-url=https://web.archive.org/web/20230329102222/https://www.bmj.com/content/bmj/suppl/2011/01/05/bmj.c5347.DC1/deeb200710.ww1_default.pdf |url-status=live }}
On 5 January 2011, BMJ published an article by Brian Deer entitled "How the case against the MMR vaccine was fixed". Deer said that, based on examination of the medical records of the 12 children in the original study, his research had found:{{cite journal |title=How the case against the MMR vaccine was fixed |last=Deer |first=Brian |journal=BMJ |date=5 January 2011 |volume=342 |pmid=21209059 |pages=c5347 |url=http://www.bmj.com/content/342/bmj.c5347.full |doi=10.1136/bmj.c5347 |s2cid=46683674 |doi-access= |access-date=6 January 2011 |archive-date=12 January 2011 |archive-url=https://web.archive.org/web/20110112100916/http://www.bmj.com/content/342/bmj.c5347.full |url-status=live }}
{{Blockquote|The paper in The Lancet was a case series of 12 child patients; it reported a proposed "new syndrome" of enterocolitis and regressive autism and associated this with MMR as an "apparent precipitating event." But in fact:
: Three of nine children reported with regressive autism did not have autism diagnosed at all. Only one child clearly had regressive autism;
: Despite the paper claiming that all 12 children were "previously normal", five had documented pre-existing developmental concerns;
: Some children were reported to have experienced first behavioural symptoms within days of MMR, but the records documented these as starting some months after vaccination;
: In nine cases, unremarkable colonic histopathology results—noting no or minimal fluctuations in inflammatory cell populations—were changed after a medical school "research review" to "non-specific colitis";
: The parents of eight children were reported as blaming MMR, but 11 families made this allegation at the hospital. The exclusion of three allegations—all giving times to onset of problems in months—helped to create the appearance of a 14-day temporal link;
: Patients were recruited through anti-MMR campaigners, and the study was commissioned and funded for planned litigation.}}
In an accompanying editorial, BMJ editors said:
{{blockquote|1=Clear evidence of falsification of data should now close the door on this damaging vaccine scare ... Who perpetrated this fraud? There is no doubt that it was Wakefield. Is it possible that he was wrong, but not dishonest: that he was so incompetent that he was unable to fairly describe the project, or to report even one of the 12 children's cases accurately? No. A great deal of thought and effort must have gone into drafting the paper to achieve the results he wanted: the discrepancies all led in one direction; misreporting was gross. Moreover, although the scale of the GMC's 217-day hearing precluded additional charges focused directly on the fraud, the panel found him guilty of dishonesty concerning the study's admissions criteria, its funding by the Legal Aid Board, and his statements about it afterwards.}}
The British Medical Journal editorial concluded that Wakefield's paper was an "elaborate fraud".{{cite journal |year=2011 |doi=10.1136/bmj.c7452 |page=c7452 |volume=342 |title=Wakefield's article linking MMR vaccine and autism was fraudulent |vauthors=Godlee F, Smith J, Marcovitch H |journal=BMJ |url=http://www.bmj.com/content/342/bmj.c7452.full |pmid=21209060 |s2cid=43640126 |access-date=6 January 2011 |archive-date=11 November 2013 |archive-url=https://web.archive.org/web/20131111093448/http://www.bmj.com/content/342/bmj.c7452.full |url-status=live }}{{cite news |url=https://www.npr.org/blogs/health/2011/01/06/132703314/study-linking-childhood-vaccine-and-autism-was-fraudulent |publisher=NPR |agency=Associated Press |title=Study linking vaccine to autism was fraud |date=6 January 2011 |access-date=6 January 2011 |archive-url=https://web.archive.org/web/20110107180150/http://www.npr.org/blogs/health/2011/01/06/132703314/study-linking-childhood-vaccine-and-autism-was-fraudulent |archive-date=7 January 2011 |url-status=live}}
In a BMJ follow-up article on 11 January 2011,{{cite journal |journal=BMJ |date=11 January 2011 |page=c5258 |volume=342 |doi=10.1136/bmj.c5258 |title=How the vaccine crisis was meant to make money |last=Deer |first=Brian |url=http://www.bmj.com/content/342/bmj.c5258.full |pmid=21224310 |s2cid=37724643 |access-date=12 January 2011 |archive-date=26 December 2019 |archive-url=https://web.archive.org/web/20191226091152/https://www.bmj.com/content/342/bmj.c5258.full |url-status=live }} Deer stated that Wakefield had planned to capitalize on the MMR vaccination scare provoked by his paper.{{cite news |url=http://www.cnn.com/2011/HEALTH/01/11/autism.vaccines/?hpt=Sbin |title=Vaccine study's author held related patent, medical journal reports |work=CNN |date=11 January 2011 |access-date=12 January 2011 |archive-date=27 January 2019 |archive-url=https://web.archive.org/web/20190127235332/http://www.cnn.com/2011/HEALTH/01/11/autism.vaccines/?hpt=Sbin |url-status=live }} He said that based upon documents he had obtained under Freedom of information legislation,{{cite news |last=Stein |first=Rob |date=11 January 2011 |title=Wakefield tried to capitalize on autism-vaccine link, report says |newspaper=The Washington Post |url=http://voices.washingtonpost.com/checkup/2011/01/wakefield_tried_to_capitalize.html |access-date=12 January 2011 |archive-url=https://web.archive.org/web/20120630205839/http://voices.washingtonpost.com/checkup/2011/01/wakefield_tried_to_capitalize.html |archive-date=30 June 2012 |url-status=dead }} Wakefield—in partnership with the father of one of the boys in the study—had planned to launch a venture on the back of an MMR vaccination scare that would profit from new medical tests and "litigation driven testing". The Washington Post reported that Deer said that Wakefield predicted he "could make more than $43 million a year from diagnostic kits" for the new condition, autistic enterocolitis. According to Deer's report in BMJ, the ventures, Immunospecifics Biotechnologies Ltd and Carmel Healthcare Ltd—named after Wakefield's wife—failed after Wakefield's superiors at University College London's medical school gave him a two-page letter that said:
{{blockquote|We remain concerned about a possible serious conflict of interest between your academic employment by UCL, and your involvement with Carmel ... This concern arose originally because the company's business plan appears to depend on premature, scientifically unjustified publication of results, which do not conform to the rigorous academic and scientific standards that are generally expected.}}
WebMD reported on Deer's BMJ report, saying that the $43 million predicted yearly profits would come from marketing kits for "diagnosing patients with autism" and that "the initial market for the diagnostic will be litigation-driven testing of patients with AE [autistic enterocolitis, an unproven condition concocted by Wakefield] from both the UK and the US".{{cite web |last=Russell |first=Peter |date=11 January 2011 |title=MMR Doctor 'Planned to Make Millions,' Journal Claims |url=http://www.webmd.com/brain/autism/news/20110111/mmr-doctor-planned-make-millions-journal-claims |archive-url=https://web.archive.org/web/20110115215830/http://www.webmd.com/brain/autism/news/20110111/mmr-doctor-planned-make-millions-journal-claims |archive-date=15 January 2011 |access-date=12 January 2011 |website=WebMD}} According to WebMD, the BMJ article also claimed that Carmel Healthcare Ltd. would succeed in marketing products and developing a replacement vaccine if "public confidence in the MMR vaccine [were] damaged".
In October 2012, research published in PNAS, the Proceedings of the National Academy of Sciences, identified Wakefield's 1998 paper as the most cited retracted scientific paper, with 758 citations, and gave the "reason for retraction" as "fraud".{{cite journal |first=FC |last=Fang |title=Misconduct accounts for the majority of retracted scientific publications |journal=Proceedings of the National Academy of Sciences |date=October 2012 |doi=10.1073/pnas.1212247109 |author2=Steen RG |author3=Casadevall A |volume=109 |issue=42 |pages=17028–17033 |pmid=23027971 |pmc=3479492 |bibcode=2012PNAS..10917028F |doi-access=free}}
= Journal retractions =
On 2 February 2010, The Lancet formally retracted Wakefield's 1998 paper.{{cite news |url=http://www.timesonline.co.uk/tol/life_and_style/health/article7012267.ece |title=Lancet journal retracts Andrew Wakefield MMR scare paper |last=Rose |first=David |date=3 February 2010 |work=The Times |archive-url=https://web.archive.org/web/20110410083057/http://www.timesonline.co.uk/tol/life_and_style/health/article7012267.ece |archive-date=10 April 2011 |location=London |url-status=dead}}{{Cite news |url=https://www.nytimes.com/2010/02/03/health/research/03lancet.html |title=British Journal Retracts Paper Linking Autism and Vaccines |last=Harris |first=Gardiner |date=2 February 2010 |work=The New York Times |access-date=8 February 2019 |language=en-US |issn=0362-4331 |archive-date=18 February 2010 |archive-url=https://web.archive.org/web/20100218074131/http://www.nytimes.com/2010/02/03/health/research/03lancet.html |url-status=live }}{{cite news |last=Park |first=Madison |date=2 February 2010 |title=Medical journal retracts study linking autism to vaccine |website=CNN |url=http://www.cnn.com/2010/HEALTH/02/02/lancet.retraction.autism/index.html?section=cnn_latest |access-date=2 February 2010 |archive-url=https://web.archive.org/web/20121109033029/http://www.cnn.com/2010/HEALTH/02/02/lancet.retraction.autism/index.html?section=cnn_latest |archive-date=9 November 2012}} The retraction states: "The claims in the original paper that children were 'consecutively referred' and that investigations were 'approved' by the local ethics committee have been proven to be false."
The following day, the editor of a specialist journal, NeuroToxicology, withdrew another Wakefield paper that was in press. The article, which concerned research on monkeys, had already been published online and sought to implicate vaccines in autism.{{cite journal |first=L |last=Hewitson |title=Withdrawn: Delayed acquisition of neonatal reflexes in newborn primates receiving a thimerosal-containing Hepatitis B vaccine: Influence of gestational age and birth weight |journal=NeuroToxicology |date=October 2009 |pmid=19800915 |doi=10.1016/j.neuro.2009.09.008 |author2=Houser LA |author3=Stott C |last4=Sackett |first4=Gene |last5=Tomko |first5=Jaime L. |last6=Atwood |first6=David |last7=Blue |first7=Lisa |last8=White |first8=E. Railey |last9=Wakefield |first9=Andrew J. |display-authors=3|doi-access= }}
In May 2010, The American Journal of Gastroenterology retracted a paper of Wakefield's that used data from the 12 patients of the article in The Lancet.{{cite journal |doi=10.1038/ajg.2010.149 |pmid=20445528 |title=Retraction: Enterocolitis in Children With Developmental Disorders |year=2010 |last=Wakefield |first=AJ |journal=The American Journal of Gastroenterology |volume=105 |page=1214 |issue=5 |author2=Anthony A |author3=Murch SH |last4=Thomson |first4=M |last5=Montgomery |first5=S M |last6=Davies |first6=S |last7=O'Leary |first7=J J |last8=Berelowitz |first8=M |last9=Walker-Smith |first9=J A |s2cid=3211063 |display-authors=3|citeseerx=10.1.1.691.3621 }}
On 5 January 2011, British Medical Journal editors recommended that Wakefield's other publications be scrutinized and retracted if need be.{{cite news |url=https://query.nytimes.com/gst/fullpage.html?res=9C02E7DC1E3BF935A35752C0A9679D8B63 |title=Study Linking Vaccine to Autism is Called Fraud, Journal Reports |newspaper=The New York Times |date=6 January 2011 |access-date=6 January 2011 |agency=Associated Press |archive-date=21 December 2016 |archive-url=https://web.archive.org/web/20161221183247/http://query.nytimes.com/gst/fullpage.html?res=9C02E7DC1E3BF935A35752C0A9679D8B63 |url-status=live }}
= Wakefield response =
As of January 2011, Wakefield continued to maintain his innocence. In a press release, he stated,
{{blockquote|1=I want to make one thing crystal clear for the record—my research and the serious medical problems found in those children were not a hoax and there was no fraud whatsoever. Nor did I seek to profit from our findings ... despite media reports to the contrary, the results of my research have been duplicated in five other countries ... I continue to fully support more independent research to determine if environmental triggers, including vaccines, are causing autism and other developmental problems ... Since the Lancet paper, I have lost my job, my career and my country. To claim that my motivation was profit is patently untrue. I will not be deterred—this issue is far too important.{{cite press release |url=http://www.prnewswire.com/news-releases/statement-from-dr-andrew-wakefield--no-fraud-no-hoax-no-profit-motive-113454389.html |title=Statement From Dr. Andrew Wakefield: No Fraud. No Hoax. No Profit Motive. |date=13 January 2011 |access-date=13 January 2011 |publisher=PRNewswire |work=PharmaLive.com |archive-date=17 January 2011 |archive-url=https://web.archive.org/web/20110117005109/http://www.prnewswire.com/news-releases/statement-from-dr-andrew-wakefield--no-fraud-no-hoax-no-profit-motive-113454389.html |url-status=live }}{{cite news |url=http://www.bmj.com/content/342/bmj.c7452.full/reply |title=BMJ replies to emails |work=BMJ |date=7 February 2011 |location=London |last=Godlee |first=Fiona |access-date=12 April 2011 |archive-date=28 September 2011 |archive-url=https://web.archive.org/web/20110928084322/http://www.bmj.com/content/342/bmj.c7452.full/reply |url-status=live }}{{cite news |last=Ziv |first=Stav |title=Andrew Wakefield, Father of the Anti-Vaccine Movement, Responds to the Current Measles Outbreak for the First Time |url=http://www.newsweek.com/2015/02/20/andrew-wakefield-father-anti-vaccine-movement-sticks-his-story-305836.html |work=Newsweek |date=10 February 2015 |access-date=17 February 2015 |archive-date=31 July 2017 |archive-url=https://web.archive.org/web/20170731161218/http://www.newsweek.com/2015/02/20/andrew-wakefield-father-anti-vaccine-movement-sticks-his-story-305836.html |url-status=live }}}}
In an Internet radio interview, Wakefield said the BMJ series "was utter nonsense" and denied "that he used the cases of the 12 children in his study to promote his business venture". Deer has filed financial disclosure forms and rejects Wakefield's claim that he is funded by the pharmaceutical industry. According to CNN, Wakefield said the patent he held was for "an 'over-the-counter nutritional supplement' that boosts the immune system". WebMD reported that Wakefield said he was the victim of "a ruthless, pragmatic attempt to crush any attempt to investigate valid vaccine safety concerns".
Wakefield says that Deer is a "hit man who was brought in to take [him] down" and that other scientists have simply taken Deer at his word. While on Anderson Cooper 360°, he said that he had not read the BMJ articles yet, but he denied their validity and denied that Deer had interviewed the families of the children in the study. He also urged viewers to read his book, Callous Disregard, which he said would explain why he was being targeted, to which Anderson Cooper replied: "But sir, if you're lying, then your book is also a lie. If your study is a lie, your book is a lie."{{Cite AV media |people=Anderson Cooper (interviewer), Andrew Wakefield (interviewee) |date=6 January 2011 |title=Autism-vaccine study author defends work |website=CNN |url=http://www.cbsnews.com/8301-504763_162-20027552-10391704.html |access-date=8 January 2011 |archive-date=23 May 2013 |archive-url=https://web.archive.org/web/20130523082155/http://www.cbsnews.com/8301-504763_162-20027552-10391704.html |url-status=dead }}
Wakefield later implied that there is a conspiracy by public health officials and pharmaceutical companies to discredit him, including suggesting they pay bloggers to post rumours about him on websites or that they artificially inflated reports of deaths from measles.{{Cite news |url=https://www.nytimes.com/2011/04/24/magazine/mag-24Autism-t.html |title=The Crash and Burn of an Autism Guru |last=Dominus |first=Susan |date=20 April 2011 |work=The New York Times |access-date=8 February 2019 |language=en-US |issn=0362-4331 |archive-date=3 April 2018 |archive-url=https://web.archive.org/web/20180403012131/https://www.nytimes.com/2011/04/24/magazine/mag-24Autism-t.html?_r=1 |url-status=live }}
= Deer counter-response =
Deer responded to Wakefield's charge by challenging Wakefield to sue him:
{{blockquote|1=If it is true that Andrew Wakefield is not guilty as charged, he has the remedy of bringing a libel action against myself, The Sunday Times of London, against the medical journal here, and he would be the richest man in America.}}
Deer mentioned that all of Wakefield's previous libel actions had been dismissed or withdrawn.
In January 2012, Wakefield filed a defamation lawsuit in Texas state court against Deer, Fiona Godlee, and the BMJ for false accusations of fraud, seeking a jury trial in Travis County. The filing identified Wakefield as a resident of Austin,{{cite news |url=http://www.statesman.com/news/local/doctor-who-did-autism-research-in-austin-sues-2085868.html |title=Doctor who did autism research in Austin sues medical journal, writers |newspaper=Austin American-Statesman |date=6 January 2012 |access-date=26 April 2013 |archive-url=https://web.archive.org/web/20120911132006/http://www.statesman.com/news/local/doctor-who-did-autism-research-in-austin-sues-2085868.html |archive-date=11 September 2012 |url-status=dead |first=Mary Ann |last=Roser }}{{cite web |url=http://www.courthousenews.com/2012/01/04/BritMedJ.pdf |title=Wakefield v. British Medical Journal, Deer, Godlee |work=District Court of Travis County, Texas |date=3 January 2012 |access-date=26 April 2013 |archive-date=16 June 2016 |archive-url=https://web.archive.org/web/20160616110734/http://www.courthousenews.com/2012/01/04/BritMedJ.pdf |url-status=live }} and cited the "Texas Long-Arm Statute" as justification for initiating the proceeding in Texas. The BMJ responded that it stood by its reports and would "defend the claim vigorously".{{cite news |first=John |last=Gever |url=https://abcnews.go.com/Health/AutismCommunity/doctor-claimed-vaccine-autism-link-sues-critics/story?id=15306948 |title=Doctor Who Claimed Vaccine-Autism Link Sues Critics |website=ABC News |date=6 January 2012 |access-date=26 April 2013 |archive-date=8 March 2019 |archive-url=https://web.archive.org/web/20190308081357/https://abcnews.go.com/Health/AutismCommunity/doctor-claimed-vaccine-autism-link-sues-critics/story?id=15306948 |url-status=live }}{{cite news |first=Ian |last=Sample |url=https://www.theguardian.com/society/2012/jan/05/andrew-wakefield-sues-bmj-mmr |title=Andrew Wakefield sues BMJ for claiming MMR study was fraudulent |newspaper=The Guardian |access-date=26 April 2013 |location=London |date=5 January 2012 |archive-date=21 April 2019 |archive-url=https://web.archive.org/web/20190421142533/https://www.theguardian.com/society/2012/jan/05/andrew-wakefield-sues-bmj-mmr |url-status=live }} In August 2012 District Court Judge Amy Meachum dismissed Wakefield's suit for lack of jurisdiction.{{cite web |url=http://www.briandeer.com/solved/slapp-jurisdiction-dismissed.pdf |title=Order on Plaintiff's Motion to Strike |website=201st District Court of Travis County, Texas |date=3 August 2012 |access-date=3 August 2012 |via=BrianDeer.com |archive-date=11 May 2013 |archive-url=https://web.archive.org/web/20130511023756/http://briandeer.com/solved/slapp-jurisdiction-dismissed.pdf |url-status=live }}{{cite news |first=Mary Ann |last=Roser |url=https://www.statesman.com/article/20120922/NEWS/309229616 |title=Wakefield, former autism researcher, can't sue for defamation in Texas, judge says |date=22 September 2012 |newspaper=Austin American-Statesman |access-date=22 May 2019 |archive-date=10 June 2019 |archive-url=https://web.archive.org/web/20190610110222/https://www.statesman.com/article/20120922/NEWS/309229616 |url-status=dead }} Her ruling was upheld on appeal in September 2014 and Wakefield was ordered to pay all parties' costs.{{cite web |url=http://www.statesman.com/news/news/court-andrew-wakefield-autism-researcher-cannot-su/nhQhN/ |title=Court: Andrew Wakefield, autism researcher, cannot sue in Texas |date=19 September 2014 |newspaper=Austin American-Statesman |access-date=20 September 2014 |archive-date=23 September 2016 |archive-url=https://web.archive.org/web/20160923122349/http://www.statesman.com/news/news/court-andrew-wakefield-autism-researcher-cannot-su/nhQhN/ |url-status=dead |first=Chuck |last=Lindell }}{{cite web |url=http://www.search.txcourts.gov/SearchMedia.aspx?MediaVersionID=5e1e5f9a-7821-4448-8e69-ecba29e40567&coa=coa03&DT=Opinion&MediaID=fbb559e2-bede-49ed-8b34-e6f71b7650ce |title=Judgment Rendered |website=Texas Court of Appeals, 3rd District, at Austin |date=19 September 2014 |access-date=20 September 2014 |archive-date=7 November 2016 |archive-url=https://web.archive.org/web/20161107191604/http://www.search.txcourts.gov/SearchMedia.aspx?MediaVersionID=5e1e5f9a-7821-4448-8e69-ecba29e40567&coa=coa03&DT=Opinion&MediaID=fbb559e2-bede-49ed-8b34-e6f71b7650ce |url-status=live }}
On 5 April 2011, Deer was named the UK's specialist journalist of the year in the British Press Awards, organised by the Society of Editors. The judges said that Deer's investigation of Wakefield was a "tremendous righting of a wrong".{{cite web |url=http://www.pressawards.org.uk/page-view.php?pagename=Specialist-Journalist-of-the-Year |work=British Press Awards |title= Specialist Journalist of the Year |date=5 April 2011 |access-date=12 April 2011 |archive-url=https://web.archive.org/web/20110411044840/http://www.pressawards.org.uk/page-view.php?pagename=Specialist-Journalist-of-the-Year |archive-date=11 April 2011 |url-status=dead }}
Epidemics, effects, and reception
{{see also|2013 Swansea measles epidemic|Measles outbreaks in the 21st century}}
Physicians, medical journals, and editors have made statements tying Wakefield's fraudulent actions to various epidemics and deaths.{{cite web |url=http://www.medpagetoday.com/Pediatrics/Autism/24203 |title=BMJ Lifts Curtain on MMR-Autism Fraud |first=John |last=Gever |website=MedPage Today |date=5 January 2011 |access-date=8 January 2011 |archive-date=14 May 2019 |archive-url=https://web.archive.org/web/20190514104731/https://www.medpagetoday.com/pediatrics/autism/24203 |url-status=live }}{{cite journal |url=http://www.bmj.com/content/342/bmj.d22.full |title=The fraud behind the MMR scare |first=F |last=Godlee |journal=BMJ |date=January 2011 |page=d22 |volume=342 |doi=10.1136/bmj.d22 |s2cid=73020733 |access-date=8 January 2011 |archive-date=13 June 2019 |archive-url=https://web.archive.org/web/20190613213348/https://www.bmj.com/content/342/bmj.d22.full |url-status=live |url-access=subscription }}{{cite web |url=http://blogs.bmj.com/bmj/2011/01/06/brian-deer-piltdown-medicine-the-missing-link-between-mmr-and-autism/ |title=Piltdown medicine: The missing link between MMR and autism |date=6 January 2011 |website=BMJ Group Blogs |last=Deer |first=Brian |access-date=8 January 2011 |archive-date=9 January 2011 |archive-url=https://web.archive.org/web/20110109074905/http://blogs.bmj.com/bmj/2011/01/06/brian-deer-piltdown-medicine-the-missing-link-between-mmr-and-autism/ |url-status=live }}{{cite web |url=http://www.webmd.com/brain/autism/news/20110106/bmj-declares-vaccine-autism-study-fraud |title=BMJ Declares Vaccine-Autism Study 'an Elaborate Fraud', 1998 Lancet Study Not Bad Science but Deliberate Fraud, Claims Journal |first=Nicky |last=Broyd |website=WebMD Health News |date=6 January 2011 |access-date=8 January 2011 |archive-date=31 March 2019 |archive-url=https://web.archive.org/web/20190331191607/https://www.webmd.com/brain/autism/news/20110106/bmj-declares-vaccine-autism-study-fraud |url-status=live }}{{cite web |first=Marissa |last=Jasek |url=http://www.wwaytv3.com/healthwatch-disputed-autism-study-sparks-debate-about-vaccines/01/2011 |title=Healthwatch: Disputed autism study sparks debate about vaccines |website=WWAY Newschannel 3 |date=6 January 2011 |access-date=7 January 2011 |url-status=dead |archive-url=https://web.archive.org/web/20110724093057/http://www.wwaytv3.com/healthwatch-disputed-autism-study-sparks-debate-about-vaccines/01/2011 |archive-date=24 July 2011}} Michael J. Smith, a professor of pediatrics at the University of Louisville, an "infectious diseases expert who has studied the autism controversy's effect on immunization rates", said, "Clearly, the results of this [Wakefield] study have had repercussions."{{cite news |url=http://www.boston.com/lifestyle/health/articles/2011/01/06/will_autism_fraud_report_be_a_vaccine_booster/ |first=Mike |last=Stobbe |date=7 January 2011 |title=Will autism fraud report be a vaccine booster? |agency=Associated Press |access-date=8 January 2011 |work=The Boston Globe |archive-date=4 March 2016 |archive-url=https://web.archive.org/web/20160304220740/http://www.boston.com/lifestyle/health/articles/2011/01/06/will_autism_fraud_report_be_a_vaccine_booster/ |url-status=live }}{{cite journal |vauthors=Smith MJ, Ellenberg SS, Bell LM, Rubin DM |title=Media coverage of the measles-mumps-rubella vaccine and autism controversy and its relationship to MMR immunization rates in the United States |journal=Pediatrics |volume=121 |issue=4 |pages=e836–843 |date=April 2008 |pmid=18381512 |doi=10.1542/peds.2007-1760 |url=http://pediatrics.aappublications.org/cgi/content/full/121/4/e836 |citeseerx=10.1.1.317.3211 |s2cid=1448617 |access-date=8 January 2011 |archive-date=10 February 2009 |archive-url=https://web.archive.org/web/20090210003036/http://pediatrics.aappublications.org/cgi/content/full/121/4/e836 |url-status=live }}
Wakefield's study and his claim that the MMR vaccine might cause autism led to a decline in vaccination rates in the United States, the United Kingdom, and Ireland, and a corresponding rise in measles and mumps infections, resulting in serious illness and deaths. His continued claims that the vaccine is harmful have contributed to a climate of distrust of all vaccines and the reemergence of other previously controlled diseases.{{cite news |last=Deer |first=Brian |url=http://www.timesonline.co.uk/tol/life_and_style/health/article5683643.ece |title=Hidden records show MMR truth |newspaper=The Sunday Times |date=19 February 2009 |location=London |access-date=6 January 2011 |archive-url=https://web.archive.org/web/20110814140548/http://www.timesonline.co.uk/tol/life_and_style/health/article5683643.ece |archive-date=14 August 2011}}{{cite journal |vauthors=Poland GA, Jacobson RM |s2cid=39229852 |title=The Age-Old Struggle against the Antivaccinationists |journal=The New England Journal of Medicine |volume=364 |issue=2 |pages=97–99 |date=13 January 2011 |pmid=21226573 |doi=10.1056/NEJMp1010594}}
The Associated Press said:
{{blockquote|1=Immunization rates in Britain dropped from 92 percent to 73 percent, and were as low as 50 percent in some parts of London. The effect was not nearly as dramatic in the United States, but researchers have estimated that as many as 125,000 US children born in the late 1990s did not get the MMR vaccine because of the Wakefield splash.}}
WWAY, an ABC affiliate in Wilmington, North Carolina, said:
{{blockquote|1=Since Dr. Andrew Wakefield's study was released in 1998, many parents have been convinced the measles, mumps and rubella vaccine could lead to autism. But that study may have done more harm than good. According to the Centers for Disease Control and Prevention, in the United States, more cases of measles were reported in 2008 than any year since 1997. More than 90 percent of those infected had not been vaccinated, or their vaccination status was not known.}}
Paul Hébert, editor-in-chief of the Canadian Medical Association Journal (CMAJ) said:
{{blockquote|1=There has been a huge impact from the Wakefield fiasco ... This spawned a whole anti-vaccine movement. Great Britain has seen measles outbreaks. It probably resulted in a lot of deaths.}}
A profile in a New York Times Magazine article commented:{{blockquote|Andrew Wakefield has become one of the most reviled doctors of his generation, blamed directly and indirectly, depending on the accuser, for irresponsibly starting a panic with tragic repercussions: vaccination rates so low that childhood diseases once all but eradicated here—whooping cough and measles, among them—have re-emerged, endangering young lives.}}
In January 2011, CNN reported: {{blockquote|1=Asked whether he thinks Wakefield should face criminal charges, Deer said, "I personally do."{{cite news |date=6 January 2011 |title=Medical journal: Study linking autism, vaccines is 'elaborate fraud' |website=CNN |url=http://edition.cnn.com/2011/HEALTH/01/06/autism.vaccines/index.html |access-date=8 January 2011 |archive-url=https://web.archive.org/web/20110107121024/http://edition.cnn.com/2011/HEALTH/01/06/autism.vaccines/index.html |archive-date=2011-01-07}}}}
On 1 April 2011, the James Randi Educational Foundation awarded Wakefield the Pigasus Award for "refusal to face reality".{{cite press release |first=Sadie |last=Crabtree |date=1 April 2011 |title=The 5 Worst Promoters of Nonsense |url=http://www.randi.org/site/jref-news/1260-pigasus-2011 |publisher=James Randi Educational Foundation |access-date=6 April 2011 |archive-date=25 July 2014 |archive-url=https://web.archive.org/web/20140725041844/http://www.randi.org/site/jref-news/1260-pigasus-2011 |url-status=live }}
A 2011 journal article described the vaccine-autism connection as "the most damaging medical hoax of the last 100 years".{{cite journal |first=DK |last=Flaherty |title=The vaccine-autism connection: a public health crisis caused by unethical medical practices and fraudulent science |journal=Ann Pharmacother |volume=45 |issue=10 |pages=1302–1304 |date=October 2011 |pmid=21917556 |doi=10.1345/aph.1Q318 |s2cid=39479569}}
In 2011, Wakefield was at the top of the list of the worst doctors of 2011 in Medscape's list of "Physicians of the Year: Best and Worst".{{cite web |url=http://www.medscape.com/features/slideshow/physicians-of-the-year/2011 |title=Physicians of the Year: Best and Worst |website=Medscape |date=2011 |access-date=16 January 2012 |archive-date=7 March 2016 |archive-url=https://web.archive.org/web/20160307005227/http://www.medscape.com/features/slideshow/physicians-of-the-year/2011 |url-status=live }} In January 2012, Time magazine named Wakefield in a list of "Great Science Frauds".{{cite magazine |url=https://healthland.time.com/2012/01/13/great-science-frauds/ |title=Great Science Frauds |first=Alice |last=Park |magazine=Time |date=13 January 2012 |access-date=16 January 2012 |archive-date=12 July 2017 |archive-url=https://web.archive.org/web/20170712045250/http://healthland.time.com/2012/01/13/great-science-frauds/ |url-status=live }} In 2012 he was awarded the Lifetime Achievement in Quackery award by the Good Thinking Society.{{Cite news |last=Jha |first=Alok |date=23 December 2012 |title=Struck off MMR doctor handed award for 'lifetime achievement in quackery' |newspaper=The Guardian |url=https://www.theguardian.com/society/2012/dec/23/struck-off-mmr-doctor-quackery-award |access-date=14 October 2014 |archive-date=22 October 2014 |archive-url=https://web.archive.org/web/20141022083708/http://www.theguardian.com/society/2012/dec/23/struck-off-mmr-doctor-quackery-award |url-status=live }}
A writer from The New York Times, who was covering a 2011 event in Tomball, Texas where Wakefield spoke, was threatened by its organizer, Michelle Guppy: "Be nice to him, or we will hurt you." Guppy is the coordinator of the Houston Autism Disability Network.
In June 2012, a local court in Rimini, Italy, ruled that the MMR vaccination had caused autism in a 15-month-old boy. The court relied heavily on Wakefield's discredited Lancet paper and largely ignored the scientific evidence presented to it. The decision was appealed.{{cite magazine |url=https://www.forbes.com/sites/emilywillingham/2013/08/09/court-rulings-dont-confirm-autism-vaccine-link/ |title=Court Rulings Don't Confirm Autism-Vaccine Link |magazine=Forbes |first=Emily |last=Willingham |date=8 August 2013 |access-date=13 August 2013 |archive-date=1 April 2019 |archive-url=https://web.archive.org/web/20190401173623/https://www.forbes.com/sites/emilywillingham/2013/08/09/court-rulings-dont-confirm-autism-vaccine-link/ |url-status=live }} On 13 February 2015, the decision was overturned by a Court of Appeals in Bologna.{{Cite news |last=Bocci |first=Michele |date=1 March 2015 |title=Autismo, i giudici assolvono il vaccino |trans-title=Autism, the judges acquit the vaccine |newspaper=la Repubblica |language=it |url=http://www.repubblica.it/salute/medicina/2015/03/01/news/autismo_i_giudici_assolvono_il_vaccino-108441541/ |access-date=4 March 2015 |archive-date=1 January 2020 |archive-url=https://web.archive.org/web/20200101054248/https://www.repubblica.it/salute/medicina/2015/03/01/news/autismo_i_giudici_assolvono_il_vaccino-108441541/ |url-status=live }}
In February 2015, Wakefield denied that he bore any responsibility for the measles epidemic that started at Disneyland. He also reaffirmed his discredited belief that "MMR contributes to the current autism epidemic". By that time at least 166 measles cases had been reported. Paul Offit did not agree, saying that the outbreak was "directly related to Dr. Wakefield's theory".{{Cite news |last=Axelrod |first=Jim |date=10 February 2015 |title=Doctor blames discredited autism research for measles outbreak |work=CBS News |url=http://www.cbsnews.com/news/doctor-blames-discredited-autism-vaccine-link-research-for-measles-outbreak/ |access-date=16 February 2015 |archive-date=22 May 2019 |archive-url=https://web.archive.org/web/20190522035346/https://www.cbsnews.com/news/doctor-blames-discredited-autism-vaccine-link-research-for-measles-outbreak/ |url-status=live }}
Filmmaker Miranda Bailey followed Wakefield and his wife Carmel and their children for five years filming a documentary about Wakefield as a person, The Pathological Optimist. According to Robert Ladendorf writing for Skeptical Inquirer magazine, Bailey attempted to remain neutral and add a "human touch", which Ladendorf says was successful. Wakefield is shown "as a soft-spoken but beleaguered family man trying to resurrect his reputation and raising money for his legal fund."{{cite journal |url=https://skepticalinquirer.org/2018/05/following-disgraced-doctor-andrew-wakefield/ |last1=Ladendorf |first1=Robert |title=Following Disgraced Doctor Andrew Wakefield |journal=Skeptical Inquirer |date=2018 |volume=42 |issue=3 |pages=60–61 |url-access=subscription |access-date=16 May 2021 |archive-date=13 August 2021 |archive-url=https://web.archive.org/web/20210813022119/https://skepticalinquirer.org/2018/05/following-disgraced-doctor-andrew-wakefield/ |url-status=live }}
In 2018, The Skeptic awarded Wakefield the Rusty Razor award "for pseudoscience and bad critical thinking."{{cite web |title=The Ockhams 2018 |url=https://www.skeptic.org.uk/the-ockham-awards/the-ockhams-2018/ |website=The Skeptic Magazine |date=18 October 2018 |access-date=11 March 2020 |archive-url=https://web.archive.org/web/20191218114513/https://www.skeptic.org.uk/the-ockham-awards/the-ockhams-2018/ |archive-date=18 December 2019}}{{cite web |last1=Hale |first1=Tom |title=This Year's Award For The Worst Pseudoscience Is Especially Deserved |url=https://www.iflscience.com/health-and-medicine/this-years-award-for-the-worst-pseudoscience-is-especially-deserved/ |website=IFL Science |date=15 October 2018 |access-date=11 March 2020 |archive-url=https://archive.today/20200311051745/https://www.iflscience.com/health-and-medicine/this-years-award-for-the-worst-pseudoscience-is-especially-deserved/ |archive-date=11 March 2020 |url-status=live }} The award is decided annually by readers' votes. Editor Deborah Hyde said, "Our contributors clearly felt that anti-vaccination damage is still a current issue, despite Mr. Wakefield first having come to public attention so long ago. These childhood diseases can do real damage, so we're proud to be an organisation that gets the good news out therethe evidence is overwhelming that vaccination is safe. Protect your children and your community by using it."{{cite web |last1=Pritchard |first1=Tom |title=This Year's 'Worst Pseudoscience Award' Goes to Anti-Vax Fraud Andrew Wakefield |url=https://www.gizmodo.co.uk/2018/10/this-years-worst-pseudoscience-award-goes-to-anti-vax-fraud-andrew-wakefield/ |website=Gizmodo |access-date=11 March 2020 |date=13 October 2018 |archive-url=https://archive.today/20200311054134/https://www.gizmodo.co.uk/2018/10/this-years-worst-pseudoscience-award-goes-to-anti-vax-fraud-andrew-wakefield/ |archive-date=11 March 2020 |url-status=dead }}
In 2022, Wakefield's fraudulent study was included on a list of "11 of the biggest lies in history".{{Cite web |last=Hoyt |first=A. |date=18 March 2022 |title=11 of the Biggest Lies in History |url=https://history.howstuffworks.com/history-vs-myth/10-biggest-lies-in-history.htm |access-date=22 March 2022 |website=HowStuffWorks.com |archive-date=5 June 2023 |archive-url=https://web.archive.org/web/20230605101736/https://history.howstuffworks.com/history-vs-myth/10-biggest-lies-in-history.htm |url-status=live }}
Political activism
Wakefield was scheduled to testify before the Oregon Senate Health Care Committee on 9 March 2015, in opposition to Senate Bill 442,{{Cite news |last=Yoo |first=Saerom |date=24 February 2015 |title=Vaccine researcher Wakefield to testify in Oregon |newspaper=Statesman Journal |url=http://www.statesmanjournal.com/story/news/health/2015/02/24/andrew-wakefield-vaccine-oregon/23967797/ |access-date=3 March 2015 |archive-date=30 October 2021 |archive-url=https://web.archive.org/web/20211030000938/https://www.statesmanjournal.com/story/news/health/2015/02/24/andrew-wakefield-vaccine-oregon/23967797/ |url-status=live }} "a bill that would eliminate nonmedical exemptions from Oregon's school immunization law". The Oregon Chiropractic Association had invited him. The chairman of the committee then canceled the meeting "after it became clear that" Wakefield planned to testify. She denied that her decision had anything to do with Wakefield's plans.{{Cite news |last=Yoo |first=Saerom |date=26 February 2015 |title=Meeting on vaccine mandate bill canceled |newspaper=Statesman Journal |url=http://www.statesmanjournal.com/story/news/health/2015/02/25/meeting-vaccine-mandate-bill-canceled/24020213/ |access-date=3 March 2015 |archive-date=30 October 2021 |archive-url=https://web.archive.org/web/20211030000937/https://www.statesmanjournal.com/story/news/health/2015/02/25/meeting-vaccine-mandate-bill-canceled/24020213/ |url-status=live }}
On 24 April 2015, Wakefield received two standing ovations from the students at Life Chiropractic College West when he told them to oppose Senate Bill 277 (SB 277), a bill that proposes elimination of non-medical vaccine exemptions.{{Cite news |last=Allday |first=Erin |date=25 April 2015 |title=Anti-vaccine leader tells parents to fight immunization bill |newspaper=San Francisco Chronicle |url=http://www.sfchronicle.com/health/article/Former-doc-who-linked-vaccines-to-autism-tells-6222613.php |access-date=25 April 2015 |archive-date=27 May 2015 |archive-url=https://web.archive.org/web/20150527191903/http://www.sfchronicle.com/health/article/Former-doc-who-linked-vaccines-to-autism-tells-6222613.php |url-status=live }} Wakefield had previously been a featured speaker at a 2014 "California Jam" gathering of chiropractors,{{Cite journal |last=Collins |first=Caitlin |journal=Lifelines |issue=Winter 2014 |title=Cal Jam in Review |publisher=Life Chiropractic College West |url=http://lifewest.edu/wp-content/uploads/2014/03/Winter2014-2.pdf |access-date=25 April 2015 |archive-url=https://web.archive.org/web/20180924184907/http://lifewest.edu/wp-content/uploads/2014/03/Winter2014-2.pdf |archive-date=24 September 2018 |url-status=dead}} as well as a 2015 "California Jam" seminar, with continuing education credits, sponsored by Life Chiropractic College West.{{Cite web |title=California Jam (March 2015 CA) |url=http://pr.mo.gov/chiropractors-ceu-course-schedule.asp?detail=3014 |website=Missouri Division of Professional Registration |access-date=25 April 2015 |archive-date=24 September 2018 |archive-url=https://web.archive.org/web/20180924184910/http://pr.mo.gov/chiropractors-ceu-course-schedule.asp?detail=3014 |url-status=live }} On 3 July 2015, Wakefield participated in a protest held in Santa Monica, California, against SB 277,{{cite news |url=http://www.latimes.com/local/westside/la-me-anti-vaccine-rally-20150704-story.html |title=Opponents vow to overturn vaccination law at Santa Monica rally |first=Kim |last=Christensen |date=3 July 2015 |access-date=5 July 2015 |newspaper=Los Angeles Times |archive-date=25 September 2018 |archive-url=https://web.archive.org/web/20180925025642/http://www.latimes.com/local/westside/la-me-anti-vaccine-rally-20150704-story.html |url-status=live }} a recently enacted bill which removed the personal belief exemption to school vaccine requirements in California state law.{{cite web |url=http://www.latimes.com/opinion/editorials/la-ed-0202-vaccination-rates-20160201-story.html |title=California's new vaccine law is already a success |date=1 February 2016 |website=Los Angeles Times |access-date=24 September 2018 |archive-date=29 March 2023 |archive-url=https://web.archive.org/web/20230329021020/https://www.latimes.com/opinion/editorials/la-ed-0202-vaccination-rates-20160201-story.html |url-status=live }}
Regarding his anti-vaccine advocacy, Wakefield has been described as a conspiracy theorist by ThinkProgress,{{cite web |last1=Covert |first1=Bryce |title=DeNiro Pulls Anti-Vaxxer Documentary From Tribeca Film Festival |url=https://thinkprogress.org/update-deniro-pulls-anti-vaxxer-documentary-from-tribeca-film-festival-b76f29079bbe/ |website=ThinkProgress |date=26 March 2016 |access-date=3 August 2021 |archive-date=17 October 2021 |archive-url=https://web.archive.org/web/20211017054454/https://thinkprogress.org/update-deniro-pulls-anti-vaxxer-documentary-from-tribeca-film-festival-b76f29079bbe/ |url-status=live }} The Washington Post,{{cite news |last1=Sun |first1=Lena |title=Trump energizes the anti-vaccine movement in Texas |url=https://www.washingtonpost.com/national/health-science/trump-energizes-the-anti-vaccine-movement-in-texas/2017/02/20/795bd3ae-ef08-11e6-b4ff-ac2cf509efe5_story.html |access-date=3 August 2021 |newspaper=The Washington Post |publisher=Fred Ryan |date=20 February 2017 |archive-date=15 April 2019 |archive-url=https://web.archive.org/web/20190415234000/https://www.washingtonpost.com/national/health-science/trump-energizes-the-anti-vaccine-movement-in-texas/2017/02/20/795bd3ae-ef08-11e6-b4ff-ac2cf509efe5_story.html |url-status=live }} The Guardian,{{cite news |last1=Boseley |first1=Sarah |title=How disgraced anti-vaxxer Andrew Wakefield was embraced by Trump's America |url=https://www.theguardian.com/society/2018/jul/18/how-disgraced-anti-vaxxer-andrew-wakefield-was-embraced-by-trumps-america |access-date=3 August 2021 |work=The Guardian |date=18 July 2018 |archive-date=16 December 2020 |archive-url=https://web.archive.org/web/20201216084528/https://www.theguardian.com/society/2018/jul/18/how-disgraced-anti-vaxxer-andrew-wakefield-was-embraced-by-trumps-america |url-status=live }} the Los Angeles Times,{{cite news |last1=Bever |first1=Lindsey |title=Whooping cough vaccine given to pregnant women does not increase risk of autism in children, study shows |url=https://www.latimes.com/nation/ct-vaccine-pregnant-women-autism-20180813-story.html |access-date=3 August 2021 |work=The Los Angeles Times |date=13 August 2018 |archive-date=29 July 2021 |archive-url=https://web.archive.org/web/20210729221428/https://www.latimes.com/nation/ct-vaccine-pregnant-women-autism-20180813-story.html |url-status=dead }} Wired,{{cite magazine |last1=Glaser |first1=April |title=A Skeptic Infiltrates a Cruise for Conspiracy Theorists |url=https://www.wired.com/2016/02/conspira-sea-cruise-know-truth/ |magazine=Wired |publisher=Conde Nast |access-date=3 August 2021 |archive-date=28 May 2023 |archive-url=https://web.archive.org/web/20230528083118/https://www.wired.com/2016/02/conspira-sea-cruise-know-truth/ |url-status=live }} the Johns Hopkins Bloomberg School of Public Health,{{cite web |title='Plandemic' Video Pulled – But Still Circulates |url=https://www.globalhealthnow.org/2020-05/plandemic-video-pulled-still-circulates |website=Global Health Now |publisher=Johns Hopkins School of Public Health |access-date=3 August 2021 |archive-date=29 July 2021 |archive-url=https://web.archive.org/web/20210729223149/https://www.globalhealthnow.org/2020-05/plandemic-video-pulled-still-circulates |url-status=dead }} Steven Salzberg,{{cite news |last1=Salzberg |first1=Steven |author-link=Steven Salzberg |title=Would You Trust Your Child With This Anti-Vax Ex-Doctor? |url=https://www.forbes.com/sites/stevensalzberg/2020/02/17/would-you-trust-your-children-with-this-discredited-former-doctor/ |access-date=3 August 2021 |work=Forbes |publisher=Integrated Whale Media Investments |date=17 February 2020 |archive-date=17 June 2023 |archive-url=https://web.archive.org/web/20230617205006/https://www.forbes.com/sites/stevensalzberg/2020/02/17/would-you-trust-your-children-with-this-discredited-former-doctor/ |url-status=live }} and Paul Offit.{{cite web |last1=Offit |first1=Paul |date=11 April 2016 |title=Anti-Vaccine Doc 'Vaxxed': A Doctor's Film Review |url=https://www.hollywoodreporter.com/movies/movie-reviews/anti-vaccine-doc-vaxxed-a-882651/ |archive-url=https://web.archive.org/web/20210608103631/https://www.hollywoodreporter.com/movies/movie-reviews/anti-vaccine-doc-vaxxed-a-882651/ |archive-date=8 June 2021 |access-date=3 August 2021 |website=The Hollywood Reporter |publisher=The Hollywood Reporter LLC}}
''Vaxxed'' film
{{main|Vaxxed}}
In 2016, Wakefield directed the anti-vaccination propaganda film Vaxxed: From Cover-Up to Catastrophe.{{cite news |last1=Menon |first1=Vinay |date=28 March 2016 |title=De Niro did right inoculating Tribeca Film Fest from Vaxxed: Menon |work=Toronto Star |url=https://www.thestar.com/entertainment/2016/03/28/de-niro-did-right-inoculating-tribeca-film-fest-from-vaxxed-menon.html |archive-url=https://web.archive.org/web/20160328233144/https://www.thestar.com/entertainment/2016/03/28/de-niro-did-right-inoculating-tribeca-film-fest-from-vaxxed-menon.html |archive-date=28 March 2016}}{{cite news |last1=Plait |first1=Phil |title=The Tribeca Film Festival Pulls Anti-Vax "Documentary" |url=http://www.slate.com/blogs/bad_astronomy/2016/03/27/tribeca_pulls_anti_vax_documentary_by_andrew_wakefield_from_its_lineup.html |work=Slate |date=27 March 2016 |access-date=13 January 2017 |archive-date=25 September 2018 |archive-url=https://web.archive.org/web/20180925180213/http://www.slate.com/blogs/bad_astronomy/2016/03/27/tribeca_pulls_anti_vax_documentary_by_andrew_wakefield_from_its_lineup.html |url-status=live }}{{Cite web |url=http://www.indiewire.com/article/vaxxed-from-cover-up-to-catastrophe-is-designed-to-trick-you-review-20160401 |title='Vaxxed: From Cover-Up to Catastrophe' is Designed to Trick You (Review) |last=Kohn |first=Eric |date=1 April 2016 |website=Indiewire |access-date=3 April 2016 |archive-date=3 April 2016 |archive-url=https://web.archive.org/web/20160403185102/http://www.indiewire.com/article/vaxxed-from-cover-up-to-catastrophe-is-designed-to-trick-you-review-20160401 |url-status=live }}{{cite news |url=http://www.aftenposten.no/meninger/kommentarer/Robert-De-Niro-har-gjort-seg-til-vaksinemotstandernes-nyttige-idiot--Ingeborg-Senneset-8407950.html |title=Robert De Niro har gjort seg til vaksinemotstandernes nyttige idiot |trans-title=Robert De Niro has made himself the useful idiot of vaccine opponents |first=Ingeborg |last=Senneset |date=28 March 2016 |work=Aftenposten |language=no |access-date=22 April 2016 |archive-date=31 March 2016 |archive-url=https://web.archive.org/web/20160331023749/http://www.aftenposten.no/meninger/kommentarer/Robert-De-Niro-har-gjort-seg-til-vaksinemotstandernes-nyttige-idiot--Ingeborg-Senneset-8407950.html |url-status=live }} The film purports to show "an appalling cover-up committed by the government agency charged with protecting the health of American citizens [the US Centers for Disease Control and Prevention (CDC)] ... an alarming deception that has contributed to the skyrocketing increase of autism and potentially the most catastrophic epidemic of our lifetime."{{cite web |title=Vaxxed Official Documentary Film website |url=http://www.vaxxedthemovie.com/ |website=Vaxxed |access-date=27 March 2016 |archive-date=27 March 2016 |archive-url=https://web.archive.org/web/20160327154906/http://www.vaxxedthemovie.com/ |url-status=live }} The film was withdrawn from New York's 2016 Tribeca Film Festival after the festival's founder Robert De Niro (who has a child with autism) reversed his decision to include it.{{cite news |title=Vaxxed: Tribeca festival withdraws MMR film |url=https://www.bbc.com/news/entertainment-arts-35906470 |website=BBC News |access-date=27 March 2016 |date=27 March 2016 |archive-date=27 March 2016 |archive-url=https://web.archive.org/web/20160327054552/http://www.bbc.com/news/entertainment-arts-35906470 |url-status=live }} The film was also scheduled to be projected at the Mairie de Paris but was then moved to a small private cinema.{{Cite web |title=Antivax – Les marchands de doute – Regarder le documentaire complet |url=https://www.arte.tv/fr/videos/103025-000-A/antivax-les-marchands-de-doute/ |access-date=30 December 2021 |website=ARTE |language=fr |archive-date=23 December 2021 |archive-url=https://web.archive.org/web/20211223071052/https://www.arte.tv/fr/videos/103025-000-A/antivax-les-marchands-de-doute/ |url-status=dead }} Wakefield called this action censorship.{{cite news |url=https://www.washingtonpost.com/news/morning-mix/wp/2016/03/27/filmmakers-accuse-robert-de-niro-of-censorship-after-he-yanks-anti-vaccine-movie-from-tribeca-festival/ |title=Robert De Niro accused of censorship after yanking anti-vaccine movie from film festival |last=Holley |first=Peter |date=27 March 2016 |newspaper=Washington Post |access-date=27 March 2016 |archive-date=17 November 2021 |archive-url=https://web.archive.org/web/20211117064201/https://www.washingtonpost.com/news/morning-mix/wp/2016/03/27/filmmakers-accuse-robert-de-niro-of-censorship-after-he-yanks-anti-vaccine-movie-from-tribeca-festival/ |url-status=live }} Ian Lipkin, professor of epidemiology and director of the Center for Infection and Immunity at the Columbia University Mailman School of Public Health, writing in The Wall Street Journal, said: "If Vaxxed had been submitted as science fiction, it would merit attention for its story line, character development and dialogue. But as a documentary it misrepresents what science knows about autism, undermines public confidence in the safety and efficacy of vaccines, and attacks the integrity of legitimate scientists and public-health officials".{{Cite news |url=https://www.wsj.com/articles/anti-vaccination-lunacy-wont-stop-1459721652 |title=Anti-Vaccination Lunacy Won't Stop |last=Lipkin |first=W. Ian |author-link=W. Ian Lipkin |date=3 April 2016 |work=The Wall Street Journal |access-date=8 February 2019 |language=en-US |issn=0099-9660 |archive-date=6 December 2022 |archive-url=https://web.archive.org/web/20221206073238/http://www.wsj.com/articles/anti-vaccination-lunacy-wont-stop-1459721652 |url-status=live }}
Selected publications
= Books =
{{Refbegin}}
- {{ cite book |title=The Doctor Who Fooled the World: Science, Deception, and the War on Vaccines | first=Brian |last=Deer |isbn=9781911617808 |publisher=Scribe |year=2020 }}
{{Refend}}
{{Refbegin}}
- {{cite book |title=Callous Disregard: Autism and Vaccines: The Truth Behind a Tragedy |first=Andrew J |last=Wakefield |isbn=978-1-61608-169-0 |publisher=Skyhorse Publishing |year=2010 |url=https://archive.org/details/callousdisregard00wake}}
{{Refend}}
= Journal articles =
{{Refbegin}}
- Withdrawn: {{cite journal |vauthors=Hewitson L, Houser LA, Stott C, Sackett G, Tomko JL, Atwood D, Blue L, White ER, Wakefield AJ |title=WITHDRAWN: Delayed acquisition of neonatal reflexes in newborn primates receiving a thimerosal-containing Hepatitis B vaccine: Influence of gestational age and birth weight |journal=Neurotoxicology |date=October 2009 |pmid=19800915 |doi=10.1016/j.neuro.2009.09.008|doi-access= }}
- Retracted: {{cite journal |vauthors=Wakefield AJ, Anthony A, Murch SH, Thomson M, Montgomery SM, Davies S, O'Leary JJ, Berelowitz M, Walker-Smith JA |title=Enterocolitis in children with developmental disorders |journal=Am. J. Gastroenterol. |volume=95 |issue=9 |pages=2285–2295 |date=September 2000 |doi=10.1111/j.1572-0241.2000.03248.x |pmid=11007230 |s2cid=22460603}}{{Retracted|doi=10.1038/ajg.2010.149|pmid=20445528|intentional=yes}}
- Retracted: {{cite journal |vauthors=Wakefield AJ, Murch SH, Anthony A, Linnell J, Casson DM, Malik M, Berelowitz M, Dhillon AP, Thomson MA, Harvey P, Valentine A, Davies SE, Walker-Smith JA |title=Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children |journal=The Lancet |volume=351 |issue=9103 |pages=637–641 |year=1998 |pmid=9500320 |doi=10.1016/S0140-6736(97)11096-0 |s2cid=439791}}{{Retracted|doi=10.1016/S0140-6736(10)60175-4|pmid=20137807|http://retractionwatch.com/the-retraction-watch-leaderboard/top-10-most-highly-cited-retracted-papers/ Retraction Watch|http://retractionwatch.com/2015/02/03/frauds-long-tail-measles-outbreak-shows-important-look-downstream-retractions/ Retraction Watch|intentional=yes}}
- {{cite journal |doi=10.1016/0016-5085(95)90467-0 |vauthors=Wakefield AJ, Ekbom A, Dhillon AP, Pittilo RM, Pounder RE |title=Crohn's disease: pathogenesis and persistent measles virus infection |journal=Gastroenterology |volume=108 |issue=3 |pages=911–916 |date=March 1995 |pmid=7875495}}
- {{cite journal |doi=10.1002/jmv.1890390415 |vauthors=Wakefield AJ, Pittilo RM, Sim R, Cosby SL, Stephenson JR, Dhillon AP, Pounder RE |title=Evidence of persistent measles virus infection in Crohn's disease |journal=J. Med. Virol. |volume=39 |issue=4 |pages=345–353 |date=April 1993 |pmid=8492105 |s2cid=29899812}}
- {{cite journal |last=Wakefield |first=AJ |title=Granulomatous vasculitis in Crohn's disease |journal=Gastroenterology |volume=100 |issue=5 Pt 1 |pages=1279–1287 |date=May 1991 |pmid=2013373 |author2=Sankey EA |author3=Dhillon AP |last4=Sawyerr |first4=AM |last5=More |first5=L |last6=Sim |first6=R |last7=Pittilo |first7=RM |last8=Rowles |first8=PM |last9=Hudson |first9=M |display-authors=3 |doi=10.1016/0016-5085(91)90779-K|doi-access=free }}
- {{cite journal |vauthors=Wakefield AJ, Sawyerr AM, Dhillon AP, Pittilo RM, Rowles PM, Lewis AA, Pounder RE |title=Pathogenesis of Crohn's disease: multifocal gastrointestinal infarction |journal=The Lancet |volume=2 |issue=8671 |pages=1057–1062 |date=November 1989 |pmid=2572794 |doi=10.1016/s0140-6736(89)91078-7 |s2cid=23490194}}
{{Refend}}
See also
Notes
{{notelist}}
References
{{Reflist}}
External links
- {{Cite journal |first=A |last=Alaszewski |s2cid=72887825 |doi=10.1136/bmj.d236 |title=How campaigners and the media push bad science |journal=BMJ |volume=342 |page=d236 |year=2011}}
- {{cite journal |last=Deer |first=Brian |title=Secrets of the MMR scare. The Lancet's two days to bury bad news |journal=BMJ |volume=342 |page=c7001 |year=2011 |pmid=21245118 |url=http://www.bmj.com/content/342/bmj.c7001 |doi=10.1136/bmj.c7001 |s2cid=9232871 |doi-access=|url-access=subscription }}
- {{Cite journal |first=F |last=Godlee |doi=10.1136/bmj.d378 |title=Institutional and editorial misconduct in the MMR scare |journal=BMJ |volume=342 |page=d378 |year=2011 |s2cid=72501916 |url=http://www.bmj.com/content/342/bmj.d378}}
- {{cite press release |url=http://www.fic.nih.gov/News/Events/Pages/fiona-godlee-mrr.aspx |title=Lessons from the MMR Scare by Fiona Godlee |date=6 September 2011 |publisher=Fogarty International Center, National Institutes of Health |access-date=30 December 2013 |archive-date=7 January 2021 |archive-url=https://web.archive.org/web/20210107132709/https://www.fic.nih.gov/News/Events/Pages/fiona-godlee-mrr.aspx |url-status=dead }}
- {{cite journal |vauthors=Opel DJ, Diekema DS, Marcuse EK |title=Assuring research integrity in the wake of Wakefield |journal=BMJ |volume=342 |page=d2 |year=2011 |pmid=21245120 |doi=10.1136/bmj.d2 |s2cid=206892864 |url=http://www.bmj.com/content/342/bmj.d2}}
- {{cite web |url=https://www.pbs.org/wgbh/pages/frontline/vaccines/ |title=The Vaccine War |work=Frontline |publisher=PBS |date=27 April 2010 |access-date=30 December 2013}} Updated March 2015.
- {{cite book |last=Deer |first=Brian |date=2020 |title=The Doctor Who Fooled the World: Andrew Wakefield's war on vaccines |location=London |publisher=Scribe UK |isbn=978-1-91161-780-8}}
{{Pseudoscience}}
{{Authority control}}
{{DEFAULTSORT:Wakefield, Andrew}}
Category:Alumni of Imperial College London
Category:Alumni of St Mary's Hospital Medical School
Category:British anti-vaccination activists
Category:English conspiracy theorists
Category:Medical controversies in the United Kingdom
Category:Medical doctors struck off by the General Medical Council
Category:Medical scandals in the United Kingdom
Category:Place of birth missing (living people)
Category:People educated at King Edward's School, Bath
Category:People involved in scientific misconduct incidents