Glossary of cellular and molecular biology (0–L)#A
{{Short description|none}}
This glossary of cellular and molecular biology is a list of definitions of terms and concepts commonly used in the study of cell biology, molecular biology, and related disciplines, including genetics, biochemistry, and microbiology.{{#invoke:cite web||url=https://www.genome.gov/genetics-glossary|title=Talking Glossary of Genomic and Genetic Terms|date=8 October 2017|publisher=genome.gov|access-date=8 October 2017}} It is split across two articles:
- This page, Glossary of cellular and molecular biology (0–L), lists terms beginning with numbers and with the letters A through L.
- Glossary of cellular and molecular biology (M–Z) lists terms beginning with the letters M through Z.
This glossary is intended as introductory material for novices (for more specific and technical detail, see the article corresponding to each term). It has been designed as a companion to Glossary of genetics and evolutionary biology, which contains many overlapping and related terms; other related glossaries include Glossary of virology and Glossary of chemistry.
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{{compact ToC|num=yes|center=yes|seealso=yes|refs=yes|extlinks=yes|nobreak=yes|m=M|n=N|o=O|p=P|q=Q|r=R|s=S|t=T|u=U|v=V|w=W|x=X|y=Y|z=Z}}
0–9
{{glossary}}
{{term|3' untranslated region (3'-UTR)}}
{{ghat|Also three-prime untranslated region, 3' non-translated region (3'-NTR), and trailer sequence.}}
{{term|3'-end}}{{anchor|3' end|3'}}
{{ghat|Also three-prime end.}}
Image:Nukleotid num.svg group are also shown.]]
{{term|5' cap}}
{{ghat|Also five-prime cap.}}
{{term|5' untranslated region (5'-UTR)}}
{{ghat|Also five-prime untranslated region, 5' non-translated region (5'-NTR), and leader sequence.}}
{{term|5-bromodeoxyuridine}}
{{term|5'-end}}{{anchor|5' end|5'}}
{{ghat|Also five-prime end.}}
{{term|5-methyluracil}}
{{glossary end}}
{{Glossary of genetics ToC}}
A
{{glossary}}
{{term|acentric}}
{{term|acetyl coenzyme A (acetyl-CoA)}}{{anchor|acetyl coenzyme A|acetyl-CoA}}
File:Acetyl-CoA-2D colored.svg highlighted in blue]]
{{term|acetylation}}{{anchor|acetylate|acetylates|acetylating|acetylated}}
{{term|acetyltransferase}}{{anchor|acetyltransferases}}
{{term|acrocentric}}
{{term|action potential}}
{{term|activation}}
{{term|activator}}{{anchor|activators}}
{{term|active site}}{{anchor|active sites}}
{{ghat|Also binding site and catalytic site.}}
{{term|active transport}}
{{term|term=adenine|content=adenine ({{font|A|font=courier|size=large}})}}
{{term|term=adenosine|content=adenosine ({{font|A|font=courier|size=large}})}}
{{term|adenosine diphosphate (ADP)}}{{anchor|adenosine diphosphate|ADP}}
{{term|adenosine monophosphate (AMP)}}{{anchor|adenosine monophosphate|AMP}}
{{term|adenosine triphosphate (ATP)}}{{anchor|adenosine triphosphate|ATP}}
{{term|A-DNA}}{{anchor|A-DNA}}
{{term|affected relative pair}}
{{term|alkaline lysis}}
{{term|allele}}{{anchor|alleles|allelic}}
{{term|allosome}}{{anchor|sex chromosome|sex chromosomes|allosomes}}
{{ghat|Also sex chromosome, heterochromosome, or idiochromosome.}}
{{term|alpha helix (α-helix)}}
{{term|alternative splicing}}
{{ghat|Also differential splicing or simply splicing.}}
{{term|amber}}
{{term|amino acid}}{{anchor|amino acids}}
File:Amino acid generic structure.png (blue), one carboxyl group (red), and one variable side chain (green). The side chain, which can range from a simple methyl group (alanine) to more complex functional groups such as a double-ringed indole (tryptophan), gives each particular amino acid its unique identity. During {{gli|glossary=Glossary of cellular and molecular biology (M–Z)|translation}}, amino acids are joined into a linear chain by condensation reactions which create {{gli|glossary=Glossary of cellular and molecular biology (M–Z)|peptide bonds}} between the carboxyl group of one amino acid and the amino group of an adjacent amino acid. The first and last amino acids in the chain are said to be {{gli|glossary=Glossary of cellular and molecular biology (M–Z)|N-terminal}} and {{gli|C-terminal}}, respectively, in reference to the unbonded amino group of the first amino acid and the unbonded carboxyl group of the last.]]
{{term|amino terminus}}
{{term|aminoacyl-tRNA synthetase}}
{{ghat|Also tRNA-ligase.}}
{{term|aminoacyl-tRNA (aa-tRNA)}}
{{ghat|Also aminoacylated tRNA and charged tRNA.}}
{{term|amplicon}}
{{term|amplification}}
{{term|anaphase}}
{{term|anaphase lag}}
{{term|aneucentric}}
{{term|aneuploidy}}{{anchor|aneuploid}}
{{term|annealing}}{{anchor|anneal|anneals|annealed}}
{{term|antibody}}{{anchor|antibodies}}
{{term|anticodon}}{{anchor|anticodons}}
{{term|antimetabolite}}{{anchor|antimetabolites}}
{{term|antimitotic}}{{anchor|antimetabolites}}
{{term|antioncogene}}
{{term|antiparallel}}
{{term|antiporter}}{{anchor|antiporters}}
{{term|antisense}}
{{term|antisense RNA (asRNA)}}{{anchor|asRNA|antisense RNA}}
{{ghat|Also antisense transcript and antisense oligonucleotide (ASO).}}
{{term|anucleate}}
{{ghat|Also anuclear.}}
{{term|apical constriction}}
File:Apicalconstriction fig1.jpg
{{term|apoptosis}}
{{term|aptamer}}{{anchor|aptamers}}
{{term|artificial gene synthesis}}
{{term|assimilatory process}}
{{term|aster}}
{{term|asynapsis}}
{{term|attached X}}
{{ghat|Also compound X.}}
{{term|autolysis}}
{{term|autosome}}{{anchor|autosomes|autosomal}}
{{term|autozygote}}
{{term|auxesis}}
{{term|axenic}}
{{glossary end}}
{{Glossary of genetics ToC}}
B
{{glossary}}
{{term|B chromosome}}
{{term|back mutation}}
{{term|bacterial artificial chromosome (BAC)}}
{{term|balancer chromosome}}
{{term|base}}
{{term|base pair (bp)}}{{anchor|base pairs|base pairing|base-pair|pairing|paired}}
{{term|baseline}}
{{term|basic local alignment search tool (BLAST)}}
{{term|B-DNA}}{{anchor|B-DNA}}
{{term|beta oxidation}}
{{term|bidirectional replication}}
{{term|binary fission}}
{{term|binding site}}{{anchor|binding sites}}
{{term|bioassay}}{{anchor|bioassays}}
{{term|biochemical pathway}}{{anchor|biochemical pathways}}
{{term|bioenergetics}}
{{term|biofilm}}{{anchor|biofilms}}
{{term|biomarker}}{{anchor|biomarkers}}
{{term|biomolecular gradient}}
{{term|biomolecule}}{{anchor|biomolecules|biomolecular}}
{{ghat|Also biological molecule.}}
{{term|bivalent}}
{{term|blast cell}}
{{term|blot}}{{anchor|blots|blotting|blotted}}
{{term|blunt end}}{{anchor|blunt ends}}
{{term|bromodeoxyuridine (BUDR, BrdU)}}
{{ghat|Also 5-bromodeoxyuridine.}}
{{glossary end}}
{{Glossary of genetics ToC}}
C
{{glossary}}
{{term|cadastral gene}}
{{term|cadherin}}{{anchor|cadherins}}
{{term|callus}}
{{term|candidate gene}}{{anchor|candidate genes}}
{{term|canonical sequence}}
{{term|carbohydrate}}{{anchor|carbohydrates}}
{{term|carboxyl terminus}}
{{term|carrier protein}}{{anchor|carrier proteins}}
{{term|caspase}}
{{term|cassette}}{{anchor|cassettes|gene cassette|gene cassettes}}
{{term|CCAAT box}}
{{ghat|Also CAAT box or CAT box.}}
{{term|cDNA}}
{{term|cell}}{{anchor|cells}}
{{term|cell biology}}
{{ghat|Also cellular biology.}}
{{term|cell compartmentalization}}{{anchor|cell compartmentalization|cell compartment|cell compartments|compartment|compartments|compartmentalization}}
{{term|cell cortex}}
{{term|cell counting}}
{{term|cell culture}}
{{term|cell cycle}}
{{term|cell division}}{{anchor|cell divisions}}
{{term|cell fusion}}
{{term|cell membrane}}{{anchor|cell membranes|plasma membrane|plasmalemma}}
{{ghat|Also plasma membrane, cytoplasmic membrane, and plasmalemma.}}
File:Cell membrane detailed diagram en.svg
{{term|cell physiology}}
{{term|cell polarity}}
{{term|cell signaling}}{{anchor|signaling|cell communication}}
{{ghat|Also cell communication.}}
{{term|cell surface receptor}}{{anchor|cell surface receptors}}
{{term|cell wall}}{{anchor|cell walls}}
{{term|cell-free DNA (cfDNA)}}
{{term|cellular}}
{{term|cellular differentiation}}
{{term|cellular immunity}}
{{ghat|Also cell-mediated immunity.}}
{{term|cellular noise}}
{{term|cellular reprogramming}}
{{term|cellular senescence}}
{{term|centimorgan (cM)}}
{{ghat|Also map unit (m.u.).}}
{{term|central dogma of molecular biology}}
File:Central dogma of molecular biology colorized+special transfer.png
{{term|centriole}}{{anchor|centrioles}}
{{term|centromere}}{{anchor|centromeres}}
{{term|centromeric index}}
{{term|centrosome}}{{anchor|centrosomes}}
{{term|cfDNA}}
{{term|channel protein}}{{anchor|channel proteins}}
{{term|Chargaff's rules}}
{{term|charged tRNA}}
{{term|chDNA}}
{{term|chemiosmosis}}{{anchor|chemiosmotic}}
{{term|chemokinesis}}
{{term|chemotaxis}}
{{term|chiasma}}{{anchor|chiasmata}}
{{ghat|(pl.) chiasmata}}
{{term|chimerism}}{{anchor|chimera}}
{{term|chloroplast}}{{anchor|chloroplasts}}
{{term|chloroplast DNA (cpDNA, chDNA, ctDNA)}}
{{term|chondriome}}
{{term|chromatid}}{{anchor|chromatids}}
{{term|chromatin}}
{{term|chromatin immunoprecipitation (ChIP)}}
{{term|chromocenter}}
{{term|chromomere}}
{{ghat|Also idiomere.}}
{{term|chromosomal crossover}}{{anchor|chromosomal crossovers|crossover|crossovers}}
{{ghat|Also crossing over.}}
{{term|chromosomal DNA}}
{{term|chromosomal duplication}}
{{term|chromosomal instability}}
{{term|chromosome}}{{anchor|chromosomes|chromosomal}}
{{term|chromosome condensation}}
{{term|chromosome segregation}}
{{anchor|segregation|segregate|segregates|segregating|segregated}}
{{term|chromosome walking}}
{{term|cilium}}{{anchor|cilia}}
{{ghat|(pl.) cilia}}
{{term|circular DNA}}
{{term|circulating tumor DNA (ctDNA)}}
{{term|cis}}
{{term|cis-acting}}
{{term|cis-dominant mutation}}
{{term|cisgenesis}}
{{term|cis-regulatory element (CRE)}}
{{ghat|Also cis-regulatory module (CRM).}}
{{term|cisterna}}{{anchor|cisternae}}
{{ghat|(pl.) cisternae}}
{{term|cistron}}{{anchor|cistrons|cistronic}}
{{term|citric acid cycle}}
{{term|classical genetics}}
{{term|cleavage}}{{anchor|cleave|cleaves|cleaved|cleaving}}
{{term|cleavage furrow}}
{{term|clonal selection}}
{{term|cloning}}{{anchor|cloned}}
{{term|closed chromatin}}
{{term|coactivator}}{{anchor|coactivators}}
{{term|coding strand}}
{{ghat|Also sense strand, positive (+) sense strand, and nontemplate strand.}}
{{term|codon}}{{anchor|codons}}
{{term|codon usage bias}}
{{term|coenocyte}}
{{term|coenzyme}}{{anchor|coenzymes}}
{{term|coenzyme A (CoA)}}{{anchor|coenzyme A|CoA}}
{{ghat|Also abbreviated SHCoA and CoASH.}}
{{term|cofactor}}{{anchor|cofactors}}
{{term|comparative genomic hybridization (CGH)}}{{anchor|comparative genomic hybridization}}
{{term|competence}}{{anchor|competent|competent cell|competent cells}}
{{term|complementarity}}{{anchor|complementary|complement|complements}}
{{term|complementary DNA (cDNA)}}
{{ghat|Also copy DNA.}}
{{term|compound X}}
{{term|conditional expression}}
{{term|confluence}}{{anchor|confluent}}
{{ghat|Also confluency.}}
{{term|conformation}}{{anchor|conformations}}
{{term|conformational change}}{{anchor|conformational changes}}
{{term|congression}}
{{term|consensus sequence}}
{{ghat|Also canonical sequence.}}
{{term|conservative replication}}
{{term|conserved sequence}}
{{term|constitutive expression}}
{{term|contact inhibition}}
{{ghat|Also contact inhibition of growth or density-dependent inhibition.}}
{{term|contig}}{{anchor|contigs}}
{{term|cooperativity}}
{{ghat|Also cooperative binding.}}
{{term|copy DNA (cDNA)}}
{{term|copy error}}{{anchor|copy errors}}
{{term|copy-number variation (CNV)}}{{anchor|copy number}}
{{term|coregulator}}{{anchor|coregulators}}
{{term|corepressor}}{{anchor|corepressors}}
{{term|cosmid}}{{anchor|cosmids}}
{{term|cpDNA}}
{{term|CpG island}}{{anchor|CpG islands}}
{{ghat|Also CG island and C-G island.}}
{{term|CpG site}}{{anchor|CpG sites|CpG|CG|C-G}}
{{ghat|Also CG site and C-G site.}}
{{term|CRISPR gene editing}}
{{ghat|Also CRISPR/Cas9 gene editing.}}
{{term|crista}}{{anchor|cristae}}
{{ghat|(pl.) cristae}}
{{term|crossing over}}
{{term|crosslink}}{{anchor|crosslinks|crosslinking|crosslinked}}
{{ghat|Also cross-link.}}
File:Formaldehyde Crosslinking reaction.png (red).]]
{{term|ctDNA}}
{{term|C-terminus}}{{anchor|C-terminal|c-terminal}}
{{ghat|Also carboxyl terminus.}}
{{term|cut}}
{{term|C-value}}
{{term|C-value enigma}}
{{ghat|Also C-value paradox.}}
{{term|cyclic adenosine monophosphate (cAMP)}}
{{term|cyclosis}}
{{term|term=cytidine|content=cytidine ({{font|C|font=courier|size=large}}, Cyd)}}
{{term|cytochemistry}}
{{term|cytogenetics}}
{{term|cytokine}}{{anchor|cytokines}}
{{term|cytokinesis}}
{{term|cytology}}{{anchor|cytological}}
{{term|cytolysis}}
{{term|cytometer}}
{{term|cytomics}}
{{term|cytoplasm}}{{anchor|cytoplasmic}}
{{term|cytoplasmic streaming}}
{{ghat|Also protoplasmic streaming and cyclosis.}}
{{term|cytoplast}}{{anchor|cytoplasts}}
{{term|term=cytosine|content=cytosine ({{font|C|font=courier|size=large}})}}
{{term|cytosol}}{{anchor|cytosolic}}
{{ghat|Also hyaloplasm and groundplasm.}}
{{glossary end}}
{{Glossary of genetics ToC}}
D
{{glossary}}
{{term|daughter cell}}{{anchor|daughter cells}}
{{term|Denoising Algorithm based on Relevance network Topology}}
{{term|de novo mutation}}{{anchor|de novo mutation}}
{{term|de novo synthesis}}{{anchor|de novo synthesis}}
{{term|deacetylation}}{{anchor|deacetylate|deacetylates|deacetylating|deacetylated}}
{{term|decellularization}}
{{term|degeneracy}}{{anchor|codon degeneracy}}
{{term|degranulation}}
{{term|deletion}}{{anchor|deletions}}
{{ghat|Denoted in shorthand with the symbol Δ.}}
{{term|demethylation}}{{anchor|demethylate|demethylates|demethylating|demethylated}}
{{term|denaturation}}{{anchor|denature|denatures|denatured|denaturing}}
{{term|deoxyadenosine}}
{{ghat|Abbreviated in shorthand with {{font|dA|font=courier|size=big}}.}}
{{term|deoxycytidine}}
{{ghat|Abbreviated in shorthand with {{font|dC|font=courier|size=big}}.}}
{{term|deoxyguanosine}}
{{ghat|Abbreviated in shorthand with {{font|dG|font=courier|size=big}}.}}
{{term|deoxyribonuclease (DNase)}}
{{term|deoxyribonucleic acid (DNA)}}{{anchor|deoxyribonucleic acid|DNA}}
{{term|deoxyribonucleotide}}{{anchor|deoxyribonucleotides}}
{{term|deoxyribose}}
{{ghat|Also 2-deoxyribose.}}
File:The_difference_between_ribose_and_deoxyribose.png
{{term|deoxythymidine}}
{{term|dephosphorylation}}{{anchor|dephosphorylate|dephosphorylates|dephosphorylating|dephosphorylated}}
{{term|depurination}}
{{term|derivatization}}{{anchor|derivatize|derivatizes|derivatized|derivatizing}}
{{term|desmosome}}{{anchor|desmosomes}}
{{term|destination vector}}
{{term|desynapsis}}
{{term|developmental biology}}
{{term|diakinesis}}
{{term|dicentric}}
{{term|differentiation}}{{anchor|differentiate|differentiates|differentiating|differentiated}}
{{term|dimer}}{{anchor|dimers}}
{{term|dinucleotide}}{{anchor|dinucleotides}}
{{term|diploid}}
{{ghat|Denoted in shorthand with the somatic number 2n.}}
{{term|diplonema}}
{{ghat|Also diplotene stage.}}
{{term|direct repeat}}{{anchor|direct repeats}}
{{term|directionality}}{{anchor|direction|directions|5' to 3'|3' to 5'|5'-to-3'|3'-to-5'}}
{{term|disaccharide}}{{anchor|disaccharides}}
{{term|dispersive replication}}
{{term|dissimilatory process}}
{{term|distance measure}}
{{term|DNA}}
{{term|DNA barcoding}}
{{term|DNA condensation}}
{{term|DNA fingerprinting}}
{{term|DNA methylation}}
{{term|DNA microarray}}
{{term|DNA polymerase}}
{{term|DNA repair}}
{{term|DNA replication}}
File:Eukaryotic_DNA_replication.svg
{{term|DNA sequencing}}{{anchor|sequencing}}
{{term|DNA turnover}}
{{term|DNA-binding domain (DBD)}}
File:Transcription factors DNA binding sites.svg
{{term|DNA-binding protein (DBP)}}{{anchor|DNA-binding proteins}}
{{term|DNase}}
{{term|domain}}{{anchor|domains|protein domain|protein domains}}
{{term|donor vector}}
{{term|dosage compensation}}
{{term|double helix}}
{{term|double-strand break (DSB)}}{{anchor|double-strand breaks}}
{{term|double-stranded}}{{anchor|duplex}}
{{term|double-stranded DNA (dsDNA)}}{{anchor|dsRNA}}
{{term|double-stranded RNA (dsRNA)}}{{anchor|dsRNA}}
{{term|downregulation}}
{{ghat|Also repression or suppression.}}
{{term|downstream}}
{{term|dsDNA}}
{{term|dsRNA}}
{{term|duplex}}
{{term|duplication}}
{{term|dyad}}
{{term|dysplasia}}
{{glossary end}}
{{Glossary of genetics ToC}}
E
{{glossary}}
{{term|eat-me signal}}
{{term|electron transport chain}}
{{term|electrophoresis}}{{anchor|electrophoretic|electrophoretically}}
{{term|electroporation}}
{{ghat|Also electropermeabilization.}}
{{term|elongation}}
{{ghat|Also extension.}}
{{term|elongation factor}}{{anchor|elongation factors}}
{{term|embryo}}{{anchor|embryos|embryonic}}
{{term|emergenesis}}
{{term|endocytosis}}
{{term|endomembrane}}
{{term|endonuclease}}{{anchor|endonucleases}}
{{term|endoplasmic reticulum (ER)}}
{{term|endosome}}{{anchor|endosomes}}
{{term|enhancer}}{{anchor|enhancers}}
{{term|enhancer RNA (eRNA)}}
{{term|enucleate}}{{anchor|enucleates|enucleating|enucleated}}
{{term|envagination}}
{{term|enzyme}}{{anchor|enzymes|enzymatic}}
{{term|epigenetics}}{{anchor|epigenetic}}
{{term|epigenome}}
{{term|episome}}{{anchor|episomes|episomal}}
{{term|epistasis}}{{anchor|epistatic}}
{{term|epitope}}{{anchor|epitopes}}
{{ghat|Also antigenic determinant.}}
{{term|ergosome}}
{{term|euchromatin}}{{anchor|euchromatic}}
{{ghat|Also open chromatin.}}
{{term|euploidy}}
{{term|evolution}}
{{term|ex vivo}}
{{term|excision}}
{{term|exocytosis}}
{{term|exome}}
{{term|exon}}{{anchor|exons|exonic}}
{{term|exon skipping}}
{{term|exonuclease}}{{anchor|exonucleases}}
{{term|exosome}}
{{term|exosome complex}}
{{term|expression vector}}
{{ghat|Also expression construct.}}
File:pET28a-T7-lacO-GFP.svg (GFP). The vector also includes a gene for the lac repressor (lacI) and a gene conferring resistance to the antibiotic kanamycin (KanR), as well as various {{gli|glossary=Glossary of cellular and molecular biology (M–Z)|promoters}} for driving the expression of these genes.]]
{{term|extein}}
{{term|extension}}
{{term|extracellular}}
{{term|extracellular matrix (ECM)}}{{anchor|extracellular matrix}}
{{ghat|Also intercellular matrix.}}
{{term|extrachromosomal DNA}}
{{ghat|Also extranuclear DNA and cytoplasmic DNA.}}
{{glossary end}}
{{Glossary of genetics ToC}}
F
{{glossary}}
{{term|facilitated diffusion}}
{{term|facultative expression}}
{{term|fatty acid}}{{anchor|fatty acids}}
{{term|fermentation}}{{anchor|ferment|ferments|fermenting|fermented}}
{{term|filopodium}}{{anchor|filopodia}}
{{term|find-me signal}}
{{term|five-prime cap}}
{{term|five-prime end}}
{{term|five-prime untranslated region}}
{{term|fixation}}
{{term|fixative}}{{anchor|fixatives}}
{{term|flagellate}}
{{term|flagellum}}{{anchor|flagella}}
{{ghat|(pl.) flagella}}
{{term|fluorescence in situ hybridization (FISH)}}{{anchor|fluorescence in situ hybridization|FISH}}
{{term|forward genetics}}
{{term|forward mutation}}
{{term|frameshift mutation}}
{{term|freeze-drying}}
{{term|Functional Genomics Data (FGED) Society}}
{{ghat|Formerly known by the abbreviation MGED.}}
{{glossary end}}
{{Glossary of genetics ToC}}
G
{{glossary}}
{{term|G banding}}
{{ghat|Also Giemsa banding or G-banding.}}
{{term|G1}}
{{term|G2}}
{{term|gamete}}{{anchor|gametes|gametic|gametic cell|gametic cells|gametogenesis}}
{{term|gametogenesis}}
{{term|GC content}}
{{term|gDNA}}
{{term|gene}}{{anchor|genes}}
{{term|gene cassette}}
{{term|gene dosage}}
{{term|gene duplication}}{{anchor|duplication|duplicate|duplicates|duplicated|duplicating}}
{{ghat|Also gene amplification.}}
{{term|gene expression}}{{anchor|express|expression|expressed|expressing}}
File:Gene structure eukaryote 2 annotated.svg
{{term|Gene Expression Omnibus (GEO)}}
{{term|gene fusion}}
{{term|gene mapping}}
{{term|gene of interest (GOI)}}{{anchor|genes of interest}}
{{term|gene product}}{{anchor|gene products|products}}
{{term|gene regulation}}{{anchor|regulation|regulate|regulating|regulated|regulatory}}
{{term|gene silencing}}{{anchor|silencing}}
{{term|gene therapy}}
{{term|gene trapping}}
{{term|generation}}{{anchor|generations}}
{{term|genetic background}}{{anchor|genetic backgrounds}}
{{term|genetic code}}
{{term|genetic disorder}}{{anchor|genetic disorders}}
{{term|genetic distance}}
{{term|genetic engineering}}
{{ghat|Also genetic modification or genetic manipulation.}}
{{term|genetic marker}}{{anchor|genetic markers|marker|markers}}
{{term|genetic recombination}}
{{term|genetic redundancy}}
{{term|genetic regulatory network (GRN)}}
{{term|genetic testing}}
{{ghat|Also DNA testing or genetic screening.}}
{{term|genetically modified organism (GMO)}}
{{term|genetics}}
{{term|genome}}{{anchor|genomes|genomic}}
{{term|genome instability}}{{anchor|genomic instability}}
{{term|genome size}}
{{term|genome walking}}
{{ghat|Also chromosome walking.}}
{{term|genome-wide association study (GWAS)}}{{anchor|genome-wide association study|genome-wide association studies}}
{{term|genomic DNA (gDNA)}}
{{ghat|Also chromosomal DNA.}}
{{term|genomic imprinting}}
{{term|genomic island (GI)}}{{anchor|genomic island|genomic islands}}
{{term|genomics}}
{{term|genotoxicity}}
{{term|genotype}}{{anchor|genotypes}}
{{term|genotyping}}
{{term|germ cell}}{{anchor|germ cells}}
{{term|germ line}}
{{term|gigabase (Gb)}}{{anchor|gigabases|Gb|Gbp}}
{{term|glucogenic amino acid}}{{anchor|glucogenic amino acids}}
{{term|gluconeogenesis (GNG)}}{{anchor|gluconeogenesis}}
{{term|glucose}}
{{term|glycogen}}
{{term|glycogenolysis}}
{{term|glycolipid}}{{anchor|glycolipids}}
{{term|glycolysis}}
File:Glycolysis metabolic pathway 3 annotated.svg
{{term|glycoprotein}}{{anchor|glycoproteins}}
{{term|glycosidase}}
{{term|glycoside}}{{anchor|glycosides}}
{{term|glycosidic bond}}{{anchor|glycosidic bonds}}
{{term|glycosylation}}{{anchor|glycosylate|glycosylates|glycosylated|glycosylating}}
{{term|Goldberg-Hogness box}}
{{term|Golgi apparatus}}
{{term|gRNA}}
{{term|term=guanine|content=guanine ({{font|G|font=courier|size=large}})}}
{{term|guanine-cytosine content}}
{{ghat|Also abbreviated GC-content.}}
{{term|term=guanosine|content=guanosine ({{font|G|font=courier|size=large}}, Guo)}}
{{term|guide RNA (gRNA)}}
{{ghat|Also single guide RNA (sgRNA).}}
{{glossary end}}
{{Glossary of genetics ToC}}
H
{{glossary}}
{{term|hairpin}}
{{term|haploid}}
{{ghat|Denoted in shorthand with the somatic number n.}}
{{term|Hayflick limit}}
{{term|helicase}}{{anchor|helicases}}
{{term|hemizygous}}
{{term|heredity}}{{anchor|inheritance|inherit|inherits|inherited}}
{{ghat|Also inheritance.}}
{{term|heterochromatin}}{{anchor|heterochromatic}}
{{term|heterochromosome}}
{{term|heterodimer}}{{anchor|heterodimers}}
{{term|heterogeneous nuclear RNA (hnRNA)}}{{anchor|hnRNA|heterogeneous nuclear RNA}}
{{term|heterokaryon}}
{{term|heterologous expression}}
{{term|heterozygous}}{{anchor|heterozygote|heterozygosity}}
{{term|high-throughput}}
{{term|histology}}{{anchor|histological}}
{{term|histone}}{{anchor|histones}}
{{term|histone core}}
{{ghat|Also histone octamer and core particle.}}
{{term|histone modification}}{{anchor|histone modifications}}
{{term|histone variant}}
{{term|hnRNA}}
{{term|holocentric}}
{{term|homeobox}}{{anchor|homeoboxes}}
{{term|homeobox responsive element (HRE)}}{{anchor|homeodomain responsive element|homeobox responsive elements}}
{{ghat|Also homeodomain responsive element.}}
{{term|homeodomain}}{{anchor|homeodomains}}
{{term|homodimer}}{{anchor|homodimers}}
{{term|homologous chromosomes}}{{anchor|homologous chromosome|homolog|homologs}}
{{ghat|Also homologs or homologues.}}
{{term|homologous recombination}}
{{term|homozygous}}{{anchor|homozygote|homozygotes|homozygosity|homozygotic}}
{{term|horizontal gene transfer (HGT)}}
{{ghat|Also lateral gene transfer (LGT).}}
{{term|housekeeping gene}}{{anchor|housekeeping genes}}
{{term|Hox genes}}
{{term|Human Genome Project (HGP)}}
{{term|hyaloplasm}}
{{term|hybrid}}{{anchor|hybrids}}
{{term|hybridization}}
{{term|hybridization probe}}
{{term|hydrophilic}}
{{term|hydrophobic}}
{{ghat|Sometimes used interchangeably with lipophilic.}}
{{term|hypertonic}}
{{term|hypomorph}}
{{term|hypotonic}}
{{term|term=hypoxanthine|content=hypoxanthine ({{font|I|font=courier|size=large}})}}
{{glossary end}}
{{Glossary of genetics ToC}}
I
{{glossary}}
{{term|idiochromosome}}
{{term|idiogram}}
{{ghat|Also ideogram.}}
{{term|idiomere}}
{{term|immortalization}}{{anchor|immortalize|immortalizes|immortalizing|immortalized}}
{{term|immunogenic}}
{{term|immunohistochemistry (IHC)}}{{anchor|immunohistochemistry}}
{{term|immunostaining}}
{{term|in silico}}
{{term|in situ}}
{{term|in situ hybridization (ISH)}}{{anchor|in situ hybridization|in situ hybridization}}
{{term|in vitro}}
{{term|in vivo}}
{{term|indel}}{{anchor|indels}}
{{term|inducer}}{{anchor|inducers}}
{{term|inducible gene}}
{{term|in-frame}}
{{term|inheritance}}
{{term|initiation codon}}
{{term|inosine}}
{{term|insertion}}{{anchor|insertional|inserted|inserting}}
{{term|insertion sequence (IS)}}{{anchor|insertion sequences|insert|inserts}}
{{ghat|Also insertion element or simply insert.}}
{{term|insertional mutagenesis}}
{{term|insulator}}
{{term|integral membrane protein (IMP)}}{{anchor|integral membrane protein|integral membrane proteins}}
{{ghat|Also intrinsic membrane protein.}}
{{term|integral monotopic protein}}{{anchor|integral monotopic proteins}}
{{term|integral polytopic protein}}{{anchor|integral polytopic proteins|transmembrane protein|transmembrane proteins}}
{{ghat|Also transmembrane protein.}}
{{term|integration}}
{{term|integron}}
{{term|intein}}
{{term|intercalating agent}}
{{term|intercalation}}{{anchor|intercalate|intercalates|intercalated}}
File:Doxorubicin–DNA complex 1D12.png {{gli|intercalated}} between the bases of a DNA molecule]]
{{term|intercellular}}
{{term|intercistronic region}}
{{term|intercross}}
{{term|intergenic region (IGR)}}
{{term|intergenic spacer (IGS)}}
{{term|interkinesis}}
{{ghat|Also interphase II.}}
{{term|internal ribosome entry site (IRES)}}
{{term|interphase}}
{{term|intracellular}}
{{term|intragenic region}}
{{term|intragenic suppression}}
{{term|intragenomic conflict}}
{{term|intrinsic membrane protein}}
{{term|intrinsically disordered protein (IDP)}}{{anchor|intrinsically disordered protein|intrinsically disordered proteins}}
{{term|intron}}{{anchor|introns|intronic}}
{{ghat|Also intragenic region.}}
{{term|intron intrusion}}
{{term|intron-mediated recombination}}
{{term|intronic gene}}
{{term|invagination}}
{{term|inverted repeat}}{{anchor|inverted repeats}}
{{term|ion channel}}{{anchor|ion channels}}
{{term|ionophore}}{{anchor|ionophores}}
{{term|isochore}}{{anchor|isochores}}
{{term|isochromosome}}
{{term|isomerase}}{{anchor|isomerases}}
{{term|isomeric genes}}
{{term|isotonic}}
{{glossary end}}
{{Glossary of genetics ToC}}
J
{{glossary}}
{{term|jumping gene}}
{{term|junctional diversity}}
{{term|junk DNA}}
{{term|junk RNA}}
{{glossary end}}
{{Glossary of genetics ToC}}
K
{{glossary}}
{{term|karyogram}}
{{term|karyokinesis}}
{{term|karyolymph}}
{{term|karyon}}
{{term|karyoplasm}}
{{term|karyopyknosis}}
{{term|karyorrhexis}}
{{term|karyosome}}
{{ghat|Also karyosphere.}}
{{term|karyotype}}{{anchor|karyotypes}}
File:NHGRI human male karyotype.png
{{term|ketogenesis}}
{{term|ketogenic amino acid}}{{anchor|ketogenic amino acids}}
{{term|ketolysis}}
{{term|kilobase (kb)}}{{anchor|kilobases|kb|kbp}}
{{term|kinase}}{{anchor|kinases}}
{{term|kinesis}}
{{term|kinetochore}}{{anchor|kinetochores}}
{{term|knob}}
{{term|knockdown (KD)}}{{anchor|knockdown|knockdowns}}
{{term|knockin (KI)}}{{anchor|knockin|knockins}}
{{term|knockout (KO)}}{{anchor|knockout|knockouts}}
{{term|Kozak consensus sequence}}
{{ghat|Also simply Kozak sequence.}}
{{term|Krebs cycle}}
{{glossary end}}
{{Glossary of genetics ToC}}
L
{{glossary}}
{{term|labelling}}
{{ghat|Also tagging.}}
{{term|lagging strand}}
{{term|lampbrush chromosome}}
{{term|lateral gene transfer (LGT)}}
{{term|leader sequence}}
{{term|leading strand}}
{{term|left splicing junction}}
{{ghat|Also donor splicing junction or donor splicing site.}}
{{term|leptonema}}
{{ghat|Also leptotene stage.}}
{{term|lethal mutation}}
{{term|leucine zipper (ZIP)}}{{anchor|leucine zippers}}
{{term|ligand}}{{anchor|ligands}}
{{term|ligase}}{{anchor|ligases}}
{{term|ligation}}{{anchor|ligations|ligate|ligates|ligated}}
{{term|linkage}}{{anchor|linked|unlinked}}
{{term|linker DNA}}
{{term|linking number}}
{{term|lipid}}{{anchor|lipids}}
{{term|lipid bilayer}}{{anchor|phospholipid bilayer|bilayer}}
{{ghat|Also phospholipid bilayer.}}
{{term|lipophilic}}
{{term|lncRNA}}
{{term|locus}}{{anchor|loci}}
{{ghat|Plural loci.}}
{{term|long arm}}{{anchor|long arms}}
{{ghat|Denoted in shorthand with the symbol q.}}
{{term|long interspersed nuclear element (LINE)}}
{{term|long non-coding RNA (lncRNA)}}
{{term|lyonization}}
{{term|lysis}}{{anchor|lytic|lysing|lysed}}
{{term|lysosome}}{{anchor|lysosomes}}
{{glossary end}}
{{Glossary of genetics ToC}}
See also
References
Further reading
- {{#invoke:cite book||last=Budd |first=A. |title=Evolutionary Genomics |chapter=Introduction to Genome Biology: Features, Processes, and Structures |series=Methods in Molecular Biology |volume=855 |year=2012 |number=855 |pages=3–4|doi=10.1007/978-1-61779-582-4_1 |pmid=22407704 |isbn=978-1-61779-581-7 }}
External links
- [https://www.genome.gov/genetics-glossary National Human Genome Research Institute (NHGRI) Talking Glossary of Genomic and Genetic Terms]
- [https://www.swissbiopics.org/name/Animal_cell Interactive, labeled diagram of an animal cell from SwissBioPics]
{{Glossaries of science and engineering}}
{{MolBioGeneExp}}
{{DEFAULTSORT:Genetics Glossary}}