User:ProteinBoxBot/ASU 20080409
Log file for [[User:ProteinBoxBot|Protein Box Bot]]
Log page index: User:ProteinBoxBot/PBB_Log_Index
Protein Status Quick Log - Date: 16:39, 9 April 2008 (UTC)
==Proteins without matches (1)==
width = 750px
| ADAMTS8 |
==Redirected Proteins (24)==
==Created (22)==
==Manual Inspection (Page not found) (1)==
width = 750px
| ADAMTS8 |
==Updated (2)==
Protein Status Grid - Date: 16:39, 9 April 2008 (UTC)
class="wikitable sortable" |
HUGO Symbol
! Action Summary ! Target page(s) ! WP Symbol Search |
---|
SLC27A5
| Created | Location: SLC27A5; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=SLC27A5&fulltext=Search] |
RAB35
| Created | Location: RAB35; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=RAB35&fulltext=Search] |
ADAMTS8
| Manual Inspection (Page not found) | Other Pages: ADAM metallopeptidase with thrombospondin type 1 motif (No Data); ADAMTS8 (Redirect -> ADAMTS); ADAM-TS8 (No Data); Adam-ts8 (No Data); FLJ41712 (No Data); Flj41712 (No Data); METH2 (No Data); Meth2 (No Data); ADAMTS (DisAmbig); | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=ADAMTS8&fulltext=Search] |
RAB31
| Created | Location: RAB31; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=RAB31&fulltext=Search] |
PNRC1
| Created | Location: PNRC1; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=PNRC1&fulltext=Search] |
KDELR3
| Created | Location: KDELR3; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=KDELR3&fulltext=Search] |
RBPMS
| Updated | Location: RBPMS; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=RBPMS&fulltext=Search] |
BTN3A1
| Created | Location: BTN3A1; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=BTN3A1&fulltext=Search] |
PXMP4
| Created | Location: PXMP4; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=PXMP4&fulltext=Search] |
POLG2
| Updated | Location: POLG2; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=POLG2&fulltext=Search] |
ABCB8
| Created | Location: ABCB8; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=ABCB8&fulltext=Search] |
TDRKH
| Created | Location: TDRKH; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=TDRKH&fulltext=Search] |
BLCAP
| Created | Location: BLCAP; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=BLCAP&fulltext=Search] |
WBP4
| Created | Location: WBP4; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=WBP4&fulltext=Search] |
CD300A
| Created | Location: CD300A; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=CD300A&fulltext=Search] |
HIBADH
| Created | Location: HIBADH; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=HIBADH&fulltext=Search] |
RNF139
| Created | Location: RNF139; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=RNF139&fulltext=Search] |
DDX52
| Created | Location: DDX52; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=DDX52&fulltext=Search] |
WDR45
| Created | Location: WDR45; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=WDR45&fulltext=Search] |
ABHD2
| Created | Location: ABHD2; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=ABHD2&fulltext=Search] |
NUDT5
| Created | Location: NUDT5; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=NUDT5&fulltext=Search] |
CHD2
| Created | Location: CHD2; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=CHD2&fulltext=Search] |
NXPH3
| Created | Location: NXPH3; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=NXPH3&fulltext=Search] |
RCBTB2
| Created | Location: RCBTB2; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=RCBTB2&fulltext=Search] |
LZTS1
| Created | Location: LZTS1; | [http://en.wikipedia.org/wiki/Special:Search?ns0=1&search=LZTS1&fulltext=Search] |
Vebose Log - Date: 16:39, 9 April 2008 (UTC)
=[[ABCB8|ABCB8]]=
=[[ABHD2|ABHD2]]=
=[[ADAMTS8|ADAMTS8]]=
- INFO: Beginning work on ADAMTS8... {April 9, 2008 9:18:56 AM PDT}
- REDIRECT: Page directory gave bad page (ADAMTS8). Continuing with search.. Please correct entry: <11095,ADAMTS8>. {April 9, 2008 9:19:11 AM PDT}
- AMBIGUITY: Did not locate an acceptable page to update. {April 9, 2008 9:19:17 AM PDT}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. --> {{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = ADAM metallopeptidase with thrombospondin type 1 motif, 8
| HGNCid = 224
| Symbol = ADAMTS8
| AltSymbols =; ADAM-TS8; FLJ41712; METH2
| OMIM = 605175
| ECnumber =
| Homologene = 5108
| MGIid = 1353468
| Function = {{GNF_GO|id=GO:0004222 |text = metalloendopeptidase activity}}{{GNF_GO|id=GO:0005178 |text = integrin binding}}{{GNF_GO|id=GO:0008201 |text = heparin binding}}{{GNF_GO|id=GO:0008270 |text = zinc ion binding}}{{GNF_GO|id=GO:0009673 |text = low affinity phosphate transmembrane transporter activity}}{{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005578 |text = proteinaceous extracellular matrix}}
| Process = {{GNF_GO|id=GO:0006508 |text = proteolysis}} {{GNF_GO|id=GO:0008285 |text = negative regulation of cell proliferation}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 11095
| Hs_Ensembl =
| Hs_RefseqProtein = NP_008968
| Hs_RefseqmRNA = NM_007037
| Hs_GenLoc_db =
| Hs_GenLoc_chr =
| Hs_GenLoc_start =
| Hs_GenLoc_end =
| Hs_Uniprot =
| Mm_EntrezGene = 30806
| Mm_Ensembl = ENSMUSG00000031994
| Mm_RefseqmRNA = XM_993020
| Mm_RefseqProtein = XP_998114
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 9
| Mm_GenLoc_start = 30692127
| Mm_GenLoc_end = 30712421
| Mm_Uniprot = Q99JP1
}}
}}
ADAM metallopeptidase with thrombospondin type 1 motif, 8, also known as ADAMTS8, is a human gene.<ref name="entrez">{{cite web | title = Entrez Gene: ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11095| accessdate = }}</ref>
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.<ref name="entrez">{{cite web | title = Entrez Gene: ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11095| accessdate = }}</ref>
}}
References
{{reflist}}
Further reading
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
- {{cite journal | author=Wågsäter D, Björk H, Zhu C, et al. |title=ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques. |journal=Atherosclerosis |volume=196 |issue= 2 |pages= 514-22 |year= 2008 |pmid= 17606262 |doi= 10.1016/j.atherosclerosis.2007.05.018 }}
- {{cite journal | author=Dunn JR, Reed JE, du Plessis DG, et al. |title=Expression of ADAMTS-8, a secreted protease with antiangiogenic properties, is downregulated in brain tumours. |journal=Br. J. Cancer |volume=94 |issue= 8 |pages= 1186-93 |year= 2006 |pmid= 16570050 |doi= 10.1038/sj.bjc.6603006 }}
- {{cite journal | author=Porter S, Span PN, Sweep FC, et al. |title=ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma. |journal=Int. J. Cancer |volume=118 |issue= 5 |pages= 1241-7 |year= 2006 |pmid= 16152618 |doi= 10.1002/ijc.21476 }}
- {{cite journal | author=Dunn JR, Panutsopulos D, Shaw MW, et al. |title=METH-2 silencing and promoter hypermethylation in NSCLC. |journal=Br. J. Cancer |volume=91 |issue= 6 |pages= 1149-54 |year= 2004 |pmid= 15328519 |doi= 10.1038/sj.bjc.6602107 }}
- {{cite journal | author=Collins-Racie LA, Flannery CR, Zeng W, et al. |title=ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. |journal=Matrix Biol. |volume=23 |issue= 4 |pages= 219-30 |year= 2005 |pmid= 15296936 |doi= 10.1016/j.matbio.2004.05.004 }}
- {{cite journal | author=Ota T, Suzuki Y, Nishikawa T, et al. |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, et al. |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
- {{cite journal | author=Georgiadis KE, Hirohata S, Seldin MF, Apte SS |title=ADAM-TS8, a novel metalloprotease of the ADAM-TS family located on mouse chromosome 9 and human chromosome 11. |journal=Genomics |volume=62 |issue= 2 |pages= 312-5 |year= 2000 |pmid= 10610729 |doi= 10.1006/geno.1999.6014 }}
- {{cite journal | author=Vázquez F, Hastings G, Ortega MA, et al. |title=METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity. |journal=J. Biol. Chem. |volume=274 |issue= 33 |pages= 23349-57 |year= 1999 |pmid= 10438512 |doi= }}
}}
{{refend}}
{{protein-stub}}
=[[BLCAP|BLCAP]]=
=[[BTN3A1|BTN3A1]]=
=[[CD300A|CD300A]]=
=[[CHD2|CHD2]]=
=[[DDX52|DDX52]]=
=[[HIBADH|HIBADH]]=
- INFO: Beginning work on HIBADH... {April 9, 2008 9:19:17 AM PDT}
- UPLOAD: Added new Image to wiki: Image:PBB_Protein_HIBADH_image.jpg {April 9, 2008 9:19:58 AM PDT}
- REDIRECT: Protein Redirected to: HIBADH {April 9, 2008 9:20:05 AM PDT}
- CREATED: Created new protein page: HIBADH {April 9, 2008 9:20:10 AM PDT}
=[[KDELR3|KDELR3]]=
=[[LZTS1|LZTS1]]=
=[[NUDT5|NUDT5]]=
- INFO: Beginning work on NUDT5... {April 9, 2008 9:23:39 AM PDT}
- UPLOAD: Added new Image to wiki: Image:PBB_Protein_NUDT5_image.jpg {April 9, 2008 9:23:53 AM PDT}
- REDIRECT: Protein Redirected to: NUDT5 {April 9, 2008 9:24:00 AM PDT}
- CREATED: Created new protein page: NUDT5 {April 9, 2008 9:24:06 AM PDT}
=[[NXPH3|NXPH3]]=
=[[PNRC1|PNRC1]]=
=[[POLG2|POLG2]]=
- INFO: Beginning work on POLG2... {April 9, 2008 9:27:52 AM PDT}
- REDIRECT: Protein Redirected to: POLG2 {April 9, 2008 9:28:06 AM PDT}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {April 9, 2008 9:28:08 AM PDT}
- UPDATE SUMMARY: Updating Summary, No Errors. {April 9, 2008 9:28:08 AM PDT}
- UPDATE CITATIONS: Updating Citations, No Errors. {April 9, 2008 9:28:08 AM PDT}
- UPDATED: Updated protein page: POLG2 {April 9, 2008 9:28:10 AM PDT}
=[[PXMP4|PXMP4]]=
=[[RAB31|RAB31]]=
- INFO: Beginning work on RAB31... {April 9, 2008 9:14:48 AM PDT}
- UPLOAD: Added new Image to wiki: Image:PBB_Protein_RAB31_image.jpg {April 9, 2008 9:16:28 AM PDT}
- REDIRECT: Protein Redirected to: RAB31 {April 9, 2008 9:16:35 AM PDT}
- CREATED: Created new protein page: RAB31 {April 9, 2008 9:16:44 AM PDT}
=[[RAB35|RAB35]]=
=[[RBPMS|RBPMS]]=
- INFO: Beginning work on RBPMS... {April 9, 2008 9:13:36 AM PDT}
- REDIRECT: Protein Redirected to: RBPMS {April 9, 2008 9:14:40 AM PDT}
- UPDATE PROTEIN BOX: Updating Protein Box, No errors. {April 9, 2008 9:14:44 AM PDT}
- UPDATE SUMMARY: Updating Summary, No Errors. {April 9, 2008 9:14:44 AM PDT}
- UPDATE CITATIONS: Updating Citations, No Errors. {April 9, 2008 9:14:44 AM PDT}
- UPDATED: Updated protein page: RBPMS {April 9, 2008 9:14:48 AM PDT}
=[[RCBTB2|RCBTB2]]=
=[[RNF139|RNF139]]=
=[[SLC27A5|SLC27A5]]=
=[[TDRKH|TDRKH]]=
- INFO: Beginning work on TDRKH... {April 9, 2008 9:09:33 AM PDT}
- UPLOAD: Added new Image to wiki: Image:PBB_Protein_TDRKH_image.jpg {April 9, 2008 9:13:15 AM PDT}
- REDIRECT: Protein Redirected to: TDRKH {April 9, 2008 9:13:22 AM PDT}
- CREATED: Created new protein page: TDRKH {April 9, 2008 9:13:36 AM PDT}
=[[WBP4|WBP4]]=
- INFO: Beginning work on WBP4... {April 9, 2008 9:26:12 AM PDT}
- UPLOAD: Added new Image to wiki: Image:PBB_Protein_WBP4_image.jpg {April 9, 2008 9:27:13 AM PDT}
- REDIRECT: Protein Redirected to: WBP4 {April 9, 2008 9:27:20 AM PDT}
- CREATED: Created new protein page: WBP4 {April 9, 2008 9:27:23 AM PDT}