Login
Login

list of JWH cannabinoids

{{Short description|Substances synthesized by John W. Huffman's research group}}

The John W. Huffman research group at Clemson University synthesized over 450 cannabinoids.{{cite journal | vauthors = Manera C, Tuccinardi T, Martinelli A | year = 2008 | title = Indoles and related compounds as cannabinoid ligands | journal = Mini Rev Med Chem | volume = 8 | issue = 4| pages = 370–87 | doi = 10.2174/138955708783955935 | pmid = 18473928 }}{{cite journal | vauthors = Wiley JL, Marusich JA, Huffman JW | year = 2014 | title = Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids | journal = Life Sci | volume = 97 | issue = 1| pages = 55–63 | doi = 10.1016/j.lfs.2013.09.011 | pmid = 24071522 | pmc = 3944940 }}{{cite book | vauthors = Wiley JL, Marusich JA, Thomas BF | title = Neuropharmacology of New Psychoactive Substances (NPS) | year = 2017 | chapter = Combination Chemistry: Structure-Activity Relationships of Novel Psychoactive Cannabinoids | series = Current Topics in Behavioral Neurosciences | volume = 32 | pages = 231–248 | doi = 10.1007/7854_2016_17 | pmid = 27753007 | isbn = 978-3-319-52442-9 | doi-access = free }}{{cite book | vauthors = Banister SD, Connor M | title = New Psychoactive Substances | year = 2018 | chapter = The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonists as New Psychoactive Substances: Origins | series = Handbook of Experimental Pharmacology | volume = 252 | pages = 165–190 | doi = 10.1007/164_2018_143 | pmid = 29980914 | isbn = 978-3-030-10560-0 }} Some of those are:

class="wikitable sortable"

|+ Cannabinoids and their Ki values{{efn|Ki is the compound's binding affinity for the cannabinoid receptor type 1 (CB1) or cannabinoid receptor type 2 (CB2).}}

Name

!Class

!data-sort-type="number"|Ki / nM at CB1

!data-sort-type="number"|Ki / nM at CB2

!data-sort-type="number"|Selectivity

!class="unsortable"|Structure

JWH-004Naphthoylindole48 ± 134 ± 1.5CB2 (12x)115px
JWH-007Naphthoylindole9.5 ± 4.52.9 ± 2.6CB2 (3.3x)115px
JWH-009Naphthoylindoledata-sort-value="10000" | >10000141 ± 14CB2 (>70x)115px
JWH-011Naphthoylindole115px
JWH-015{{cite journal | vauthors = Huffman JW, Zengin G, Wu MJ, Lu J, Hynd G, Bushell K, Thompson AL, Bushell S, Tartal C, Hurst DP, Reggio PH, Selley DE, Cassidy MP, Wiley JL, Martin BR | title = Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists | journal = Bioorganic & Medicinal Chemistry | volume = 13 | issue = 1 | pages = 89–112 | date = January 2005 | pmid = 15582455 | doi = 10.1016/j.bmc.2004.09.050 }}Naphthoylindole164 ± 2213.8 ± 4.6CB2 (12x)115px
JWH-016Naphthoylindole22 ± 1.54.3 ± 1.6CB2 (5.1x)115px
JWH-018Naphthoylindole9 ± 52.9 ± 2.6CB2 (3.1x)115px
JWH-019Naphthoylindole9.8 ± 25.55 ± 2CB2 (1.77x)115px
JWH-020Naphthoylindole128 ± 17205 ± 20CB1 (1.6x)115px
JWH-030Naphthoylpyrrole87 ± 3320 ± 127CB1 (3.7x)100px
JWH-031Naphthoylpyrrole399 ± 109100px
JWH-032Naphthoylpyrroledata-sort-value="10000" | >10000data-sort-value="10000" | >10000—100px
JWH-033Naphthoylpyrrole666 ± 77100px
JWH-036Naphthoylpyrrole309 ± 11100px
JWH-042{{cite journal | vauthors = Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR | title = Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding | journal = Drug and Alcohol Dependence | volume = 60 | issue = 2 | pages = 133–40 | date = August 2000 | pmid = 10940540 | doi = 10.1016/S0376-8716(99)00152-0 }}Naphthoylindoledata-sort-value="10000" | >100005050 ± 192CB2115px
JWH-043Naphthoylindole1180 ± 44964 ± 242CB2 (1.2x)115px
JWH-044Naphthoylpyrroledata-sort-value="10000" | >10000data-sort-value="10000" | >10000—100px
JWH-045Naphthoylpyrroledata-sort-value="10000" | >10000data-sort-value="10000" | >10000—100px
JWH-046Naphthoylindole343 ± 3816.3 ± 4.9CB2 (21x)115px
JWH-047Naphthoylindole59 ± 33.47 ± 1.80CB2 (17x)115px
JWH-048Naphthoylindole10.7 ± 1.00.49 ± 0.13CB2 (22x)115px
JWH-049Naphthoylindole55.1 ± 17.032.3 ± 2.4CB2 (1.7x)115px
JWH-050Naphthoylindole342 ± 6526 ± 133CB1 (1.5x)115px
JWH-051Dibenzopyran1.200.03CB2 (40x)115px
JWH-056{{cite journal | vauthors = Huffman JW, Liddle J, Yu S, Aung MM, Abood ME, Wiley JL, Martin BR | title = 3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor | journal = Bioorganic & Medicinal Chemistry | volume = 7 | issue = 12 | pages = 2905–14 | date = December 1999 | pmid = 10658595 | doi=10.1016/s0968-0896(99)00219-9}}Dibenzopyrandata-sort-value="10000" | >1000032 ± 9CB2115px
JWH-057{{cite journal | vauthors = Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD, Reggio PH | title = Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor | journal = Journal of Medicinal Chemistry | volume = 39 | issue = 20 | pages = 3875–7 | date = September 1996 | pmid = 8831752 | doi = 10.1021/JM960394Y }}Dibenzopyran23 ± 72.9 ± 1.6CB2 (8x)115px
JWH-065Dibenzopyran399 ± 7610 ± 2CB2 (40x)115px
JWH-070Naphthoylindoledata-sort-value="10000" | >10000data-sort-value="10000" | >10000115px
JWH-071Naphthoylindole1340 ± 1232940 ± 852CB1 (2.2x)115px
JWH-072Naphthoylindole1050 ± 5.5170 ± 54CB2 (6x)115px
JWH-073Naphthoylindole8.9 ± 1.827 ± 12CB1 (3x)115px
JWH-076Naphthoylindole214 ± 11106 ± 46CB2 (2x)115px
JWH-077Naphthoylindoledata-sort-value="10000" | >10000data-sort-value="10000" | >10000115px
JWH-078Naphthoylindole817 ± 60633 ± 116CB2 (1.3x)115px
JWH-079Naphthoylindole63.0 ± 3.032.0 ± 6.0CB2 (2x)115px
JWH-080Naphthoylindole8.9 ± 1.82.21 ± 1.30CB2 (4x)115px
JWH-081Naphthoylindole1.2 ± 0.0312.4 ± 2.2CB1 (10x)115px
JWH-082Naphthoylindole5.3 ± 0.86.40 ± 0.94CB1 (1.2x)115px
JWH-083Naphthoylindole106 ± 12102 ± 50—115px
JWH-091Bow EW, Rimoldi JM. The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation. Perspect Medicin Chem. 2016 Jun 28;8:17-39. {{doi|10.4137/PMC.S32171}} {{PMID|27398024}} (Δ8-THCP)Dibenzopyran22.0 ± 3.9115px
JWH-093Naphthoylindole40.7 ± 2.859.1 ± 10.5CB1 (1.45x)115px
JWH-094Naphthoylindole476 ± 6797.3 ± 2.7CB2 (4.9x)115px
JWH-095Naphthoylindole140 ± 4.3312 ± 83CB1 (2.2x)115px
JWH-096Naphthoylindole33.7 ± 2.913.3 ± 5.6CB2 (2.5x)115px
JWH-097Naphthoylindole455 ± 28121 ± 15CB2 (3.8x)115px
JWH-098Naphthoylindole4.5 ± 0.11.9 ± 0.3CB2 (2.4x)115px
JWH-099Naphthoylindole35.3 ± 9.017.8 ± 2.9CB2 (2x)115px
JWH-100Naphthoylindole381 ± 102155 ± 74CB2 (2.5x)115px
JWH-102Dibenzopyran7.9 ± 0.95.2 ± 2.0CB2 (1.5x)115px
JWH-103Dibenzopyran28 ± 323 ± 7CB2 (1.2x)115px
JWH-116{{cite journal | vauthors = Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR | title = 3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor | journal = Bioorganic & Medicinal Chemistry | volume = 11 | issue = 4 | pages = 539–49 | date = February 2003 | pmid = 12538019 | doi = 10.1016/S0968-0896(02)00451-0 | s2cid = 29107765 }}Naphthoylindole52 ± 5115px
JWH-120Naphthoylindole1054 ± 316.1 ± 0.7CB2 (173x)115px
JWH-122Naphthoylindole0.69 ± 0.051.2 ± 1.2—115px
JWH-124 (Δ8-Parahexyl)Dibenzopyran41.0 ± 3.8115px
JWH-130 (Δ8-THCB)Dibenzopyran65.0 ± 13115px
JWH-133Dibenzopyran677 ± 1323.4 ± 1.0CB2 (200x)115px
JWH-138Martin BR, Jefferson R, Winckler R, Wiley JL, Huffman JW, Crocker PJ, Saha B, Razdan RK. Manipulation of the tetrahydrocannabinol side chain delineates agonists, partial agonists, and antagonists. J Pharmacol Exp Ther. 1999 Sep;290(3):1065-79. {{PMID|10454479}}Dibenzopyran8.5 ± 1.4115px
JWH-139{{cite journal | vauthors = Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG | title = International Union of Pharmacology. XXVII. Classification of cannabinoid receptors | journal = Pharmacological Reviews | volume = 54 | issue = 2 | pages = 161–202 | date = June 2002 | pmid = 12037135 | doi = 10.1124/pr.54.2.161 | s2cid = 8259002 }}Dibenzopyran2290 ± 50514 ± 10CB2 (164x)115px
JWH-142Dibenzopyran529 ± 4935 ± 14CB2 (15x)115px
JWH-143Dibenzopyran924 ± 10465 ± 8CB2 (14x)115px
JWH-145{{cite journal | vauthors = Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR | title = 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors | journal = Bioorganic & Medicinal Chemistry Letters | volume = 16 | issue = 20 | pages = 5432–5 | date = October 2006 | pmid = 16889960 | doi = 10.1016/j.bmcl.2006.07.051 }}Naphthoylpyrrole14 ± 26.4 ± 0.4CB2 (2.2x)115px
JWH-146Naphthoylpyrrole21 ± 262 ± 5CB2 (3.0x)100px
JWH-147Naphthoylpyrrole11 ± 17.1 ± 0.2CB2 (1.5x)100px
JWH-148Naphthoylindole123 ± 814.0 ± 1.0CB2 (8x)115px
JWH-149Naphthoylindole5.0 ± 2.10.73 ± 0.03CB2 (6.8x)115px
JWH-150Naphthoylpyrrole60 ± 115 ± 2CB2 (4x)100px
JWH-151Naphthoylindoledata-sort-value="10000" | >1000030 ± 1.1CB2 (>333x)115px
JWH-153Naphthoylindole250 ± 2411 ± 0.5CB2 (23x)115px
JWH-156Naphthoylpyrrole404 ± 18104 ± 18CB2 (4x)100px
JWH-159Naphthoylindole45 ± 110.4 ± 1.4CB2 (4.3x)115px
JWH-160Naphthoylindole1568 ± 201441 ± 110CB2 (3.6x)115px
JWH-161Dibenzopyran hybrid19.0115px
JWH-163Naphthoylindole2358 ± 215138 ± 12CB2 (17x)115px
JWH-164Naphthoylindole6.6 ± 0.76.9 ± 0.2—115px
JWH-165Naphthoylindole204 ± 2671 ± 8CB2 (2.9x)115px
JWH-166Naphthoylindole44 ± 101.9 ± 0.08CB2 (23x)115px
JWH-167Phenylacetylindole90 ± 17159 ± 14CB1 (1.77x)115px
JWH-171Hydrocarbon51115px
JWH-175Naphthylmethylindole22 ± 2115px
JWH-176Hydrocarbon26 ± 4115px
JWH-180Naphthoylindole26 ± 29.6 ± 2.0CB2 (2.7x)115px
JWH-181Naphthoylindole1.3 ± 0.10.62 ± 0.04CB2 (2.1x)115px
JWH-182Naphthoylindole0.65 ± 0.031.1 ± 0.1CB1 (1.7x)115px
JWH-184Naphthylmethylindole23 ± 6115px
JWH-185Naphthylmethylindole17 ± 3115px
JWH-186{{cite journal | vauthors = Marriott KS, Huffman JW | title = Recent advances in the development of selective ligands for the cannabinoid CB(2) receptor | journal = Current Topics in Medicinal Chemistry | volume = 8 | issue = 3 | pages = 187–204 | year = 2008 | pmid = 18289088 | doi = 10.2174/156802608783498014 }}Dibenzopyran187 ± 235.6 ± 1.7CB2 (33x)115px
JWH-187Dibenzopyran84 ± 163.4 ± 0.5CB2 (25x)115px
JWH-188Dibenzopyran270 ± 5818 ± 2CB2 (15x)115px
JWH-189Naphthoylindole52 ± 212 ± 0.8CB2 (4.3x)115px
JWH-190Dibenzopyran8.8 ± 1.41.6 ± 0.03CB2 (5.5x)115px
JWH-191Dibenzopyran1.8 ± 0.30.52 ± 0.03CB2 (3.5x)115px
JWH-192Naphthylmethylindole41 ± 13115px
JWH-193Naphthoylindole6 ± 1115px
JWH-194Naphthylmethylindole127 ± 19115px
JWH-195Naphthylmethylindole113 ± 28115px
JWH-196Naphthylmethylindole151 ± 18115px
JWH-197Naphthylmethylindole323 ± 98115px
JWH-198Naphthoylindole10 ± 2115px
JWH-199Naphthylmethylindole20 ± 2115px
JWH-200Naphthoylindole42 ± 5115px
JWH-201{{cite journal | vauthors = Huffman JW, Szklennik PV, Almond A, Bushell K, Selley DE, He H, Cassidy MP, Wiley JL, Martin BR | title = 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles | journal = Bioorganic & Medicinal Chemistry Letters | volume = 15 | issue = 18 | pages = 4110–3 | date = September 2005 | pmid = 16005223 | doi = 10.1016/j.bmcl.2005.06.008 }}Phenylacetylindole1064 ± 21444 ± 14CB2 (2.4x)115px
JWH-202Phenylacetylindole1678 ± 63645 ± 6CB2 (2.6x)115px
JWH-203Phenylacetylindole8.0 ± 0.97.0 ± 1.3—115px
JWH-204Phenylacetylindole13 ± 125 ± 1CB1 (1.9x)115px
JWH-205Phenylacetylindole124 ± 23180 ± 9CB1 (1.45x)115px
JWH-206Phenylacetylindole389 ± 25498 ± 37CB1 (1.28x)115px
JWH-207Phenylacetylindole1598 ± 1343723 ± 10CB1 (2.33x)115px
JWH-208Phenylacetylindole179 ± 7570 ± 127CB1 (3.18x)115px
JWH-209Phenylacetylindole746 ± 491353 ± 270CB1 (1.81x)115px
JWH-210Naphthoylindole0.46 ± 0.030.69 ± 0.01CB1 (1.5x)115px
JWH-211Naphthoylindole70 ± 0.812 ± 0.8CB2 (5.8x)115px
JWH-212Naphthoylindole33 ± 0.910 ± 1.2CB2 (3.3x)115px
JWH-213Naphthoylindole1.5 ± 0.20.42 ± 0.05CB2 (3.6x)115px
JWH-215Dibenzopyran1008 ± 11785 ± 21CB2 (12x)115px
JWH-216Dibenzopyran1856 ± 148333 ± 104CB2 (5.6x)115px
JWH-217Dibenzopyrandata-sort-value="10000" | >100001404 ± 66CB2 (>7x)115px
JWH-220Hydrocarbon19115px
JWH-224Dibenzopyran347 ± 3428 ± 1CB2 (12.3x)115px
JWH-225Dibenzopyrandata-sort-value="10000" | >10000325 ± 70CB2 (>31x)115px
JWH-226Dibenzopyran4001 ± 28243 ± 3CB2 (93x)115px
JWH-227Dibenzopyran40 ± 64.4 ± 0.3CB2 (9x)115px
JWH-229{{cite journal | vauthors = Huffman JW, Bushell SM, Miller JR, Wiley JL, Martin BR | title = 1-Methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Delta(8)-tetrahydrocannabinols: new selective ligands for the CB2 receptor | journal = Bioorganic & Medicinal Chemistry | volume = 10 | issue = 12 | pages = 4119–29 | date = December 2002 | pmid = 12413866 | doi=10.1016/s0968-0896(02)00331-0}}Dibenzopyran3134 ± 11018 ± 2CB2 (174x)115px
JWH-230Dibenzopyran15 ± 31.4 ± 0.12CB2 (10.7x)115px
JWH-233Dibenzopyran14 ± 31.0 ± 0.3CB2 (14x)115px
JWH-234Naphthoylindole8.4 ± 1.83.8 ± 0.6CB2 (2.2x)115px
JWH-235Naphthoylindole338 ± 34123 ± 34CB2 (2.7x)115px
JWH-236Naphthoylindole1351 ± 204240 ± 63CB2 (5.6x)115px
JWH-237Phenylacetylindole38 ± 10106 ± 2CB1 (2.8x)115px
JWH-239Naphthoylindole342 ± 2052 ± 6CB2 (6.6x)115px
JWH-240Naphthoylindole14 ± 17.2 ± 1.3CB2 (1.9x)115px
JWH-241Naphthoylindole147 ± 2049 ± 7CB2 (3.0x)115px
JWH-242Naphthoylindole42 ± 96.5 ± 0.3CB2 (6.5x)115px
JWH-243Naphthoylpyrrole285 ± 4041 ± 3CB2 (6.95x)100px
JWH-244Naphthoylpyrrole130 ± 618 ± 1CB2 (7.22x)100px
JWH-245Naphthoylpyrrole276 ± 425 ± 2CB2 (11x)100px
JWH-246Naphthoylpyrrole70 ± 416 ± 1CB2 (4.38x)100px
JWH-247Dibenzopyran427 ± 3199 ± 4CB2 (4.3x)115px
JWH-248Phenylacetylindole1028 ± 39657 ± 19CB2 (1.56x)115px
JWH-249Phenylacetylindole8.4 ± 1.820 ± 2CB1 (2.38x)115px
JWH-250Phenylacetylindole11 ± 233 ± 2CB1 (3x)115px
JWH-251Phenylacetylindole29 ± 3146 ± 36CB2 (5x)115px
JWH-252Phenylacetylindole23 ± 319 ± 1CB2 (1.2x)115px
JWH-253Phenylacetylindole62 ± 1084 ± 12CB1 (1.35x)115px
JWH-254Dibenzopyran4724 ± 509319 ± 16CB2 (14.8x)115px
JWH-256Dibenzopyran4300 ± 88897 ± 18CB2 (44x)115px
JWH-258Naphthoylindole4.6 ± 0.610.5 ± 1.3CB1 (2.3x)115px
JWH-259Naphthoylindole220 ± 2974 ± 7CB2 (3.0x)115px
JWH-260Naphthoylindole29 ± 0.425 ± 1.9CB2 (1.2x)115px
JWH-261Naphthoylindole767 ± 105221 ± 14CB2 (3.5x)115px
JWH-262Naphthoylindole28 ± 35.6 ± 0.7CB2 (5.0x)115px
JWH-265Naphthoylindole3788 ± 32380 ± 13CB2 (47x)115px
JWH-266Naphthoylindoledata-sort-value="10000" | >10000455 ± 55CB2 (>22x)115px
JWH-267Naphthoylindole381 ± 167.2 ± 0.14CB2 (53x)115px
JWH-268Naphthoylindole1379 ± 19340 ± 0.6CB2 (34x)115px
JWH-277Dibenzopyran3905 ± 91589 ± 65CB2 (6.6x)115px
JWH-278Dibenzopyran906 ± 8069 ± 6CB2 (13x)115px
JWH-292Naphthoylpyrrole29 ± 120 ± 1CB2 (1.45x)100px
JWH-293Naphthoylpyrrole100 ± 541 ± 4CB2 (2.44x)100px
JWH-298Dibenzopyran812 ± 67198 ± 23CB2 (4.1x)115px
JWH-299Dibenzopyran415 ± 5030 ± 2CB2 (13.8x)115px
JWH-300Dibenzopyran118 ± 165.3 ± 0.1CB2 (22x)115px
JWH-301Dibenzopyran295 ± 6448 ± 4CB2 (6.1x)115px
JWH-302Phenylacetylindole17 ± 289 ± 15CB1 (5.26x)115px
JWH-303Phenylacetylindole117 ± 10138 ± 12CB1 (1.18x)115px
JWH-304Phenylacetylindole3363 ± 3322679 ± 688CB2 (1.26x)115px
JWH-305Phenylacetylindole15 ± 1.829 ± 5CB1 (1.93x)115px
JWH-306Phenylacetylindole25 ± 182 ± 11CB1 (3.28x)115px
JWH-307Naphthoylpyrrole7.7 ± 1.83.3 ± 0.2CB2 (2.33x)100px
JWH-308Naphthoylpyrrole41 ± 133 ± 2CB2 (1.24x)100px
JWH-309Naphthoylpyrrole41 ± 349 ± 7CB1 (1.20x)100px
JWH-310Dibenzopyran1059 ± 5136 ± 3CB2 (29x)115px
JWH-311Phenylacetylindole23 ± 239 ± 3CB1 (1.70x)115px
JWH-312Phenylacetylindole72 ± 791 ± 20CB1 (1.26x)115px
JWH-313Phenylacetylindole422 ± 19365 ± 92CB2 (1.16x)115px
JWH-314Phenylacetylindole39 ± 276 ± 4CB1 (1.95x)115px
JWH-315Phenylacetylindole430 ± 24182 ± 23CB2 (3.36x)115px
JWH-316Phenylacetylindole2862 ± 670781 ± 105CB2 (3.66x)115px
JWH-336Dibenzopyran4589 ± 367153 ± 15CB2 (30x)115px
JWH-338Dibenzopyrandata-sort-value="10000" | >10000111 ± 16CB2 (>90x)115px
JWH-339Dibenzopyrandata-sort-value="10000" | >100002317 ± 93CB2 (>4.3x)115px
JWH-340Dibenzopyran135 ± 630 ± 1CB2 (4.5x)115px
JWH-341Dibenzopyran100 ± 810 ± 0.1CB2 (10x)115px
JWH-346Naphthoylpyrrole67 ± 639 ± 2CB2 (1.72x)100px
JWH-347Naphthoylpyrrole333 ± 17169 ± 17CB2 (1.97x)100px
JWH-348Naphthoylpyrrole218 ± 1953 ± 1CB2 (4.11x)100px
JWH-349Dibenzopyran376 ± 138 ± 4CB2 (9.9x)115px
JWH-350Dibenzopyran395 ± 5012 ± 1CB2 (33x)115px
JWH-351Dibenzopyrandata-sort-value="10000" | >10000295 ± 3CB2 (>34x)115px
JWH-352Dibenzopyrandata-sort-value="10000" | >1000047 ± 2CB2 (>213x)115px
JWH-353Dibenzopyran1493 ± 1031 ± 1CB2 (48x)115px
JWH-354Dibenzopyran1961 ± 21241 ± 14CB2 (8.1x)115px
JWH-355Dibenzopyran2162 ± 220108 ± 17CB2 (20x)115px
JWH-356Dibenzopyran5837 ± 701108 ± 17CB2 (54x)115px
JWH-357Dibenzopyran647 ± 78185 ± 4CB2 (3.5x)115px
JWH-358Dibenzopyran1243 ± 26652 ± 3CB2 (24x)115px
JWH-359Dibenzopyran2918 ± 45013.0 ± 0.2CB2 (220x)115px
JWH-360Dibenzopyran2449 ± 606160 ± 8CB2 (15x)115px
JWH-361Dibenzopyran63 ± 32.7 ± 0.1CB2 (23x)115px
JWH-362Dibenzopyran127 ± 834 ± 5CB2 (3.7x)115px
JWH-363Naphthoylpyrrole245 ± 571 ± 1CB2 (3.45x)100px
JWH-364Naphthoylpyrrole34 ± 329 ± 1CB2 (1.17x)100px
JWH-365Naphthoylpyrrole17 ± 13.4 ± 0.2CB2 (5.0x)100px
JWH-366Naphthoylpyrrole191 ± 1224 ± 1CB2 (7.96x)100px
JWH-367Naphthoylpyrrole53 ± 223 ± 1CB2 (2.30x)100px
JWH-368Naphthoylpyrrole16 ± 19.1 ± 0.7CB2 (1.76x)100px
JWH-369Naphthoylpyrrole7.9 ± 0.45.2 ± 0.3CB2 (1.52x)100px
JWH-370Naphthoylpyrrole5.6 ± 0.44.0 ± 0.5CB2 (1.40x)100px
JWH-371Naphthoylpyrrole42 ± 164 ± 2CB1 (1.52x)100px
JWH-372Naphthoylpyrrole77 ± 28.2 ± 0.2CB1 (9.39x)100px
JWH-373Naphthoylpyrrole60 ± 369 ± 2CB1 (1.15x)100px
JWH-387{{cite journal |title=Synthesis and pharmacology of 1-alkyl-3-(1-naphthoyl)indoles: Steric and electronic effects of 4- and 8-halogenated naphthoyl substituents|journal=Bioorganic & Medicinal Chemistry|volume=20|issue=6|pages=2067–2081|year=2012|vauthors=Wiley JL, Smith VJ, Chen J, Martin BR, Huffman JW |doi=10.1016/j.bmc.2012.01.038|pmid=22341572|pmc=3298571}}Naphthoylindole1.2 ± 0.11.1 ± 0.1—115px
JWH-398{{Cite book |doi=10.1007/978-1-59745-503-9 |title=The Cannabinoid Receptors |series=The Receptors |year=2009 |isbn=978-1-58829-712-9 }}Naphthoylindole2.3 ± 0.12.8 ± 0.2CB1 (1.22x)115px
JWH-416Naphthoylindole73 ± 103.3 ± 0.1CB2 (22x)115px
JWH-417Naphthoylindole522 ± 5813 ± 0.2CB2 (40x)115px
JWH-422Naphthoylindole501 ± 4820 ± 0.4CB2 (25x)115px
JWH-423Naphthoylindole140 ± 106.6 ± 0.2CB2 (21x)115px
JWH-424Naphthoylindole21 ± 3.45.4 ± 0.2CB2 (3.9x)115px
JWH-425Naphthoylindole54 ± 1110 ± 0.4CB2 (5.4x)115px

See also

Notes

{{notelist}}

References

{{reflist}}

{{Cannabinoids}}