Template:MECP2andAssociatedRettSyndrome WP3584

{{Documentation|Template:Interactive_pathway_maps/doc}}{{{header|Click on genes, proteins and metabolites below to visit related articles. The interactive pathway map can be edited at WikiPathways: {{cite web | url = http://www.wikipathways.org/index.php/Pathway:WP3584 | title = WP3584 }} }}}

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rect 779.0442579190831 610.0968996810149 859.0442579190831 630.0968996810149 [http://www.mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0000279 Go to miRBase]

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rect 880.659194864436 569.5134048560939 960.659194864436 589.5134048560939 [http://www.mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0004614 Go to miRBase]

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rect 880.6591948644362 643.1652182215167 960.6591948644362 663.1652182215167 [http://www.mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0026555 Go to miRBase]

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rect 454.69196548503334 493.6030044458841 534.6919654850333 513.6030044458842 [https://www.ncbi.nlm.nih.gov/gene/200424 Go to Entrez Gene]

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rect 779.0442579190831 493.80544883167045 859.0442579190831 513.8054488316704 [http://www.mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0000425 Go to miRBase]

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rect 72.51876818906034 117.11761027402329 152.51876818906032 137.1176102740233 [http://www.mirbase.org/cgi-bin/mature.pl?mature_acc=MIMAT0000691 Go to miRBase]

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rect 594.427733512764 519.4603179381759 674.427733512764 539.4603179381759 [https://www.ncbi.nlm.nih.gov/gene/26084 Go to Entrez Gene]

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default Go to pathway article

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{{#switch:{{{highlight}}}

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{{Annotation|0|0|[[

]]}}

|GRID1=

{{Annotation|0|0|[[

]]}}

|MIMAT0001639=

{{Annotation|0|0|[[

]]}}

|CDON=

{{Annotation|0|0|[[

]]}}

|MYT1__alt1=

{{Annotation|0|0|[[

]]}}

|CEBPD=

{{Annotation|0|0|[[

]]}}

|MiR-146=

{{Annotation|0|0|[[

]]}}

|CAMK2A=

{{Annotation|0|0|[[

]]}}

|Myelin_basic_protein=

{{Annotation|0|0|[[

]]}}

|Mir-221_microRNA=

{{Annotation|0|0|[[

]]}}

|Melatonin=

{{Annotation|0|0|[[

]]}}

|BCL6=

{{Annotation|0|0|[[

]]}}

|GABRR2=

{{Annotation|0|0|[[

]]}}

|CTCF=

{{Annotation|0|0|[[

]]}}

|Sp3_transcription_factor=

{{Annotation|0|0|[[

]]}}

|Mir-187_microRNA_precursor_family=

{{Annotation|0|0|[[

]]}}

|MIMAT0000438=

{{Annotation|0|0|[[

]]}}

|PRPF38A=

{{Annotation|0|0|[[

]]}}

|E2F1=

{{Annotation|0|0|[[

]]}}

|GRIA1=

{{Annotation|0|0|[[

]]}}

|FGF5=

{{Annotation|0|0|[[

]]}}

|RE1-silencing_transcription_factor=

{{Annotation|0|0|[[

]]}}

|Myelin-associated_glycoprotein=

{{Annotation|0|0|[[

]]}}

|Basic_fibroblast_growth_factor=

{{Annotation|0|0|[[

]]}}

|GPRIN1=

{{Annotation|0|0|[[

]]}}

|Serotonin__alt1=

{{Annotation|0|0|[[

]]}}

|Tet_methylcytosine_dioxygenase_1=

{{Annotation|0|0|[[

]]}}

|Mir-92_microRNA_precursor_family=

{{Annotation|0|0|[[

]]}}

|HNRPF=

{{Annotation|0|0|[[

]]}}

|MiR-122=

{{Annotation|0|0|[[

]]}}

|Inositol=

{{Annotation|0|0|[[

]]}}

|DNA_methylation=

{{Annotation|0|0|[[

]]}}

|Y_box_binding_protein_1=

{{Annotation|0|0|[[

]]}}

|MECP2__alt1=

{{Annotation|0|0|[[

]]}}

|MECP2__alt2=

{{Annotation|0|0|[[

]]}}

|MECP2__alt3=

{{Annotation|0|0|[[

]]}}

|Sp1_transcription_factor__alt1=

{{Annotation|0|0|[[

]]}}

|Glutamate_(neurotransmitter)__alt1=

{{Annotation|0|0|[[

]]}}

|Gamma-Aminobutyric_acid__alt1=

{{Annotation|0|0|[[

]]}}

|CREB1=

{{Annotation|0|0|[[

]]}}

|Ribosomal_protein_s6__alt1=

{{Annotation|0|0|[[

]]}}

|Brain-derived_neurotrophic_factor__alt1=

{{Annotation|0|0|[[

]]}}

|Guanidinoacetate_N-methyltransferase__alt1=

{{Annotation|0|0|[[

]]}}

|Glutamate_(neurotransmitter)__alt2=

{{Annotation|0|0|[[

]]}}

|Gamma-Aminobutyric_acid__alt2=

{{Annotation|0|0|[[

]]}}

|MECP2__alt4=

{{Annotation|0|0|[[

]]}}

}}

|caption=

}}

|bsize=

|cWidth={{#switch:{{{highlight}}}

|Dopamine=375

|Nuclear_receptor_co-repressor_1=375

|MIMAT0000279=375

|MYT1=375

|POU4F1=375

|Mir-184=375

|Mir-29_microRNA_precursor=375

|MIMAT0004614=375

|DLX5=375

|Mammalian_target_of_rapamycin=375

|Apolipoprotein_C2=375

|FGF4=375

|Gamma-Aminobutyric_acid=375

|Mir-137=375

|MIMAT0026555=375

|HDAC1=375

|Brain-derived_neurotrophic_factor=375

|Neurofibromin_1=375

|Somatostatin=375

|C5orf13=375

|FUT8=375

|TET3=375

|WP382=375

|Mir-199_microRNA_precursor_1=375

|MECP2=375

|POU3F2=375

|FGF3=375

|DLX6=375

|MIMAT0000425=375

|SMC3=375

|Mir-199_microRNA_precursor=375

|MIMAT0000691=375

|GRIN1=375

|MiR-146_1=375

|Norepinephrine=375

|MIMAT0004761=375

|MEF2C=375

|TAP1=375

|Norepinephrine__alt1=375

|UBE3A=375

|N-Methyl-D-aspartic_acid=375

|RBFOX1=375

|2',3'-Cyclic-nucleotide_3'-phosphodiesterase=375

|Glutamate_(neurotransmitter)=375

|Tet_methylcytosine_dioxygenase_2=375

|SGK=375

|Serotonin=375

|FKBP5=375

|Ribosomal_protein_s6=375

|MiR-132=375

|EZH2=375

|Guanidinoacetate_N-methyltransferase=375

|MIMAT0000227=375

|Mir-199_microRNA_precursor_1=375

|AKT1=375

|MPP1=375

|%CE%9A-opioid_receptor=375

|MiR-296=375

|ARHGEF26=375

|SIN3A=375

|Insulin-like_growth_factor_2=375

|Dopamine__alt1=375

|Sp1_transcription_factor=375

|GAD1=375

|TAF1=375

|HNRPH1=375

|MIMAT0000753=375

|CSRP1=375

|MIMAT0022697=375

|DLX5__alt1=375

|Mir-221_microRNA_1=375

|Mir-30_microRNA_precursor=375

|GRID1=375

|MIMAT0001639=375

|CDON=375

|MYT1__alt1=375

|CEBPD=375

|MiR-146=375

|CAMK2A=375

|Myelin_basic_protein=375

|Mir-221_microRNA=375

|Melatonin=375

|BCL6=375

|GABRR2=375

|CTCF=375

|Sp3_transcription_factor=375

|Mir-187_microRNA_precursor_family=375

|MIMAT0000438=375

|PRPF38A=375

|E2F1=375

|GRIA1=375

|FGF5=375

|RE1-silencing_transcription_factor=375

|Myelin-associated_glycoprotein=375

|Basic_fibroblast_growth_factor=375

|GPRIN1=375

|Serotonin__alt1=375

|Tet_methylcytosine_dioxygenase_1=375

|Mir-92_microRNA_precursor_family=375

|HNRPF=375

|MiR-122=375

|Inositol=375

|DNA_methylation=375

|Y_box_binding_protein_1=375

|MECP2__alt1=375

|MECP2__alt2=375

|MECP2__alt3=375

|Sp1_transcription_factor__alt1=375

|Glutamate_(neurotransmitter)__alt1=375

|Gamma-Aminobutyric_acid__alt1=375

|CREB1=375

|Ribosomal_protein_s6__alt1=375

|Brain-derived_neurotrophic_factor__alt1=375

|Guanidinoacetate_N-methyltransferase__alt1=375

|Glutamate_(neurotransmitter)__alt2=375

|Gamma-Aminobutyric_acid__alt2=375

|MECP2__alt4=375

|#default=1212

}}

|cHeight={{#switch:{{{highlight}}}

|Dopamine=350

|Nuclear_receptor_co-repressor_1=350

|MIMAT0000279=350

|MYT1=350

|POU4F1=350

|Mir-184=350

|Mir-29_microRNA_precursor=350

|MIMAT0004614=350

|DLX5=350

|Mammalian_target_of_rapamycin=350

|Apolipoprotein_C2=350

|FGF4=350

|Gamma-Aminobutyric_acid=350

|Mir-137=350

|MIMAT0026555=350

|HDAC1=350

|Brain-derived_neurotrophic_factor=350

|Neurofibromin_1=350

|Somatostatin=350

|C5orf13=350

|FUT8=350

|TET3=350

|WP382=350

|Mir-199_microRNA_precursor_1=350

|MECP2=350

|POU3F2=350

|FGF3=350

|DLX6=350

|MIMAT0000425=350

|SMC3=350

|Mir-199_microRNA_precursor=350

|MIMAT0000691=350

|GRIN1=350

|MiR-146_1=350

|Norepinephrine=350

|MIMAT0004761=350

|MEF2C=350

|TAP1=350

|Norepinephrine__alt1=350

|UBE3A=350

|N-Methyl-D-aspartic_acid=350

|RBFOX1=350

|2',3'-Cyclic-nucleotide_3'-phosphodiesterase=350

|Glutamate_(neurotransmitter)=350

|Tet_methylcytosine_dioxygenase_2=350

|SGK=350

|Serotonin=350

|FKBP5=350

|Ribosomal_protein_s6=350

|MiR-132=350

|EZH2=350

|Guanidinoacetate_N-methyltransferase=350

|MIMAT0000227=350

|Mir-199_microRNA_precursor_1=350

|AKT1=350

|MPP1=350

|%CE%9A-opioid_receptor=350

|MiR-296=350

|ARHGEF26=350

|SIN3A=350

|Insulin-like_growth_factor_2=350

|Dopamine__alt1=350

|Sp1_transcription_factor=350

|GAD1=350

|TAF1=350

|HNRPH1=350

|MIMAT0000753=350

|CSRP1=350

|MIMAT0022697=350

|DLX5__alt1=350

|Mir-221_microRNA_1=350

|Mir-30_microRNA_precursor=350

|GRID1=350

|MIMAT0001639=350

|CDON=350

|MYT1__alt1=350

|CEBPD=350

|MiR-146=350

|CAMK2A=350

|Myelin_basic_protein=350

|Mir-221_microRNA=350

|Melatonin=350

|BCL6=350

|GABRR2=350

|CTCF=350

|Sp3_transcription_factor=350

|Mir-187_microRNA_precursor_family=350

|MIMAT0000438=350

|PRPF38A=350

|E2F1=350

|GRIA1=350

|FGF5=350

|RE1-silencing_transcription_factor=350

|Myelin-associated_glycoprotein=350

|Basic_fibroblast_growth_factor=350

|GPRIN1=350

|Serotonin__alt1=350

|Tet_methylcytosine_dioxygenase_1=350

|Mir-92_microRNA_precursor_family=350

|HNRPF=350

|MiR-122=350

|Inositol=350

|DNA_methylation=350

|Y_box_binding_protein_1=350

|MECP2__alt1=350

|MECP2__alt2=350

|MECP2__alt3=350

|Sp1_transcription_factor__alt1=350

|Glutamate_(neurotransmitter)__alt1=350

|Gamma-Aminobutyric_acid__alt1=350

|CREB1=350

|Ribosomal_protein_s6__alt1=350

|Brain-derived_neurotrophic_factor__alt1=350

|Guanidinoacetate_N-methyltransferase__alt1=350

|Glutamate_(neurotransmitter)__alt2=350

|Gamma-Aminobutyric_acid__alt2=350

|MECP2__alt4=350

|#default=1012

}}

|oTop={{#switch:{{{highlight}}}

|Dopamine=521.485477075473

|Nuclear_receptor_co-repressor_1=253.206489391176

|MIMAT0000279=470.096899681015

|MYT1=25

|POU4F1=46.2883177331084

|Mir-184=392.279665257978

|Mir-29_microRNA_precursor=333.344387531792

|MIMAT0004614=429.513404856094

|DLX5=687

|Mammalian_target_of_rapamycin=226.175548589341

|Apolipoprotein_C2=25

|FGF4=100.432835820896

|Gamma-Aminobutyric_acid=42.1152675089957

|Mir-137=372.995663271777

|MIMAT0026555=503.165218221517

|HDAC1=252.23880597015

|Brain-derived_neurotrophic_factor=332.747674894744

|Neurofibromin_1=157.539204920385

|Somatostatin=396.345923576448

|C5orf13=25

|FUT8=138.044255425436

|TET3=353.603004445884

|WP382=266.175548589341

|Mir-199_microRNA_precursor_1=429.823389516716

|MECP2=119.674204294367

|POU3F2=65.6745383867833

|FGF3=80.4328358208956

|DLX6=687

|MIMAT0000425=353.80544883167

|SMC3=273.206489391176

|Mir-199_microRNA_precursor=25

|MIMAT0000691=25

|GRIN1=174.704227350714

|MiR-146_1=391.221085144675

|Norepinephrine=687

|MIMAT0004761=25

|MEF2C=261.563299712815

|TAP1=25

|Norepinephrine__alt1=541.485477075473

|UBE3A=682.692741628028

|N-Methyl-D-aspartic_acid=174.582360453566

|RBFOX1=280.313299712815

|2',3'-Cyclic-nucleotide_3'-phosphodiesterase=25

|Glutamate_(neurotransmitter)=25

|Tet_methylcytosine_dioxygenase_2=333.603004445884

|SGK=687

|Serotonin=687

|FKBP5=687

|Ribosomal_protein_s6=485.329937304073

|MiR-132=25

|EZH2=301.23133125

|Guanidinoacetate_N-methyltransferase=434.345923576448

|MIMAT0000227=411.068982666256

|Mir-199_microRNA_precursor_1=448.272928613108

|AKT1=246.175548589341

|MPP1=687

|%CE%9A-opioid_receptor=416.126350172038

|MiR-296=484.878504810946

|ARHGEF26=379.460317938176

|SIN3A=272.23880597015

|Insulin-like_growth_factor_2=687

|Dopamine__alt1=682.769919136297

|Sp1_transcription_factor=25

|GAD1=42.1152675089956

|TAF1=25

|HNRPH1=172.150010046685

|MIMAT0000753=489.564387845872

|CSRP1=25

|MIMAT0022697=522.671634460466

|DLX5__alt1=40.6203907953854

|Mir-221_microRNA_1=466.585632993105

|Mir-30_microRNA_precursor=25

|GRID1=687

|MIMAT0001639=506.907439920503

|CDON=25

|MYT1__alt1=65.7383177331083

|CEBPD=25

|MiR-146=372.321085144675

|CAMK2A=389.686567164178

|Myelin_basic_protein=25

|Mir-221_microRNA=450.019107979539

|Melatonin=687

|BCL6=83.8102341516926

|GABRR2=380.104972862453

|CTCF=25

|Sp3_transcription_factor=25

|Mir-187_microRNA_precursor_family=411.311044361108

|MIMAT0000438=25

|PRPF38A=139.189069635188

|E2F1=25

|GRIA1=25

|FGF5=119.432835820896

|RE1-silencing_transcription_factor=45.6745383867833

|Myelin-associated_glycoprotein=25

|Basic_fibroblast_growth_factor=60.7728638956175

|GPRIN1=452.413364002911

|Serotonin__alt1=501.485477075473

|Tet_methylcytosine_dioxygenase_1=313.603004445884

|Mir-92_microRNA_precursor_family=353.030381018523

|HNRPF=147.321401576503

|MiR-122=334.832989906579

|Inositol=687

|DNA_methylation=433.855799373041

|Y_box_binding_protein_1=119.560665366408

|MECP2__alt1=292.23880597015

|MECP2__alt2=420.261544939878

|MECP2__alt3=100.497595338652

|Sp1_transcription_factor__alt1=83.8740134980175

|Glutamate_(neurotransmitter)__alt1=25

|Gamma-Aminobutyric_acid__alt1=429.109535392194

|CREB1=528.735901155881

|Ribosomal_protein_s6__alt1=485.141849529779

|Brain-derived_neurotrophic_factor__alt1=682.692741628028

|Guanidinoacetate_N-methyltransferase__alt1=687

|Glutamate_(neurotransmitter)__alt2=683.116039077484

|Gamma-Aminobutyric_acid__alt2=687

|MECP2__alt4=548.735901155881

|#default=25

}}

|oLeft={{#switch:{{{highlight}}}

|Dopamine=10

|Nuclear_receptor_co-repressor_1=10

|MIMAT0000279=641.544257919083

|MYT1=210.647411695552

|POU4F1=10

|Mir-184=743.159194864436

|Mir-29_microRNA_precursor=742.733541811775

|MIMAT0004614=743.159194864436

|DLX5=10

|Mammalian_target_of_rapamycin=373.440438871472

|Apolipoprotein_C2=454.154997854475

|FGF4=674.276119402985

|Gamma-Aminobutyric_acid=847

|Mir-137=743.159194864436

|MIMAT0026555=743.159194864436

|HDAC1=44.8880597014956

|Brain-derived_neurotrophic_factor=198.36323993352

|Neurofibromin_1=674.276119402985

|Somatostatin=199.146938993081

|C5orf13=454.154997854475

|FUT8=674.276119402985

|TET3=317.191965485033

|WP382=373.440438871471

|Mir-199_microRNA_precursor_1=641.544257919083

|MECP2=356.850683892353

|POU3F2=79.2612568837048

|FGF3=674.276119402985

|DLX6=10

|MIMAT0000425=641.544257919083

|SMC3=10

|Mir-199_microRNA_precursor=104.974894719793

|MIMAT0000691=10

|GRIN1=674.276119402985

|MiR-146_1=641.544257919083

|Norepinephrine=182.307843754922

|MIMAT0004761=26.3656732534283

|MEF2C=199.146938993081

|TAP1=297.321401576504

|Norepinephrine__alt1=10

|UBE3A=10

|N-Methyl-D-aspartic_acid=795.74849391762

|RBFOX1=199.146938993081

|2',3'-Cyclic-nucleotide_3'-phosphodiesterase=608.172633675371

|Glutamate_(neurotransmitter)=764.517343749997

|Tet_methylcytosine_dioxygenase_2=317.191965485033

|SGK=10

|Serotonin=182.307843754922

|FKBP5=10

|Ribosomal_protein_s6=436.278213166147

|MiR-132=26.3656732534283

|EZH2=847

|Guanidinoacetate_N-methyltransferase=199.146938993081

|MIMAT0000227=641.544257919083

|Mir-199_microRNA_precursor_1=743.159194864436

|AKT1=373.440438871472

|MPP1=10

|%CE%9A-opioid_receptor=199.146938993081

|MiR-296=743.159194864436

|ARHGEF26=456.927733512764

|SIN3A=44.8880597014956

|Insulin-like_growth_factor_2=10

|Dopamine__alt1=182.307843754922

|Sp1_transcription_factor=297.321401576504

|GAD1=829.785056776429

|TAF1=297.321401576504

|HNRPH1=131.2

|MIMAT0000753=641.544257919083

|CSRP1=454.154997854475

|MIMAT0022697=743.159194864436

|DLX5__alt1=674.276119402985

|Mir-221_microRNA_1=743.159194864436

|Mir-30_microRNA_precursor=104.974894719793

|GRID1=10

|MIMAT0001639=641.544257919083

|CDON=454.154997854475

|MYT1__alt1=10

|CEBPD=297.321401576504

|MiR-146=641.544257919083

|CAMK2A=10

|Myelin_basic_protein=608.172633675371

|Mir-221_microRNA=641.544257919083

|Melatonin=182.307843754922

|BCL6=79.2612568837048

|GABRR2=545.084891414231

|CTCF=297.321401576504

|Sp3_transcription_factor=297.321401576504

|Mir-187_microRNA_precursor_family=743.159194864436

|MIMAT0000438=104.974894719793

|PRPF38A=561.136042838921

|E2F1=297.321401576504

|GRIA1=740.525213840787

|FGF5=674.276119402985

|RE1-silencing_transcription_factor=79.2612568837048

|Myelin-associated_glycoprotein=608.172633675371

|Basic_fibroblast_growth_factor=674.276119402985

|GPRIN1=199.146938993081

|Serotonin__alt1=10

|Tet_methylcytosine_dioxygenase_1=317.191965485033

|Mir-92_microRNA_precursor_family=743.159194864436

|HNRPF=131.2

|MiR-122=641.544257919083

|Inositol=182.307843754922

|DNA_methylation=316.622257053291

|Y_box_binding_protein_1=561.136042838921

|MECP2__alt1=44.8880597014925

|MECP2__alt2=43.8844548638647

|MECP2__alt3=561.136042838921

|Sp1_transcription_factor__alt1=10

|Glutamate_(neurotransmitter)__alt1=847

|Gamma-Aminobutyric_acid__alt1=544.255868751063

|CREB1=209.772297108172

|Ribosomal_protein_s6__alt1=302.077586206897

|Brain-derived_neurotrophic_factor__alt1=10

|Guanidinoacetate_N-methyltransferase__alt1=10

|Glutamate_(neurotransmitter)__alt2=88.49594824713

|Gamma-Aminobutyric_acid__alt2=182.307843754922

|MECP2__alt4=209.772297108172

|#default=10

}}

|Location=left

|Description=MECP2 and associated Rett Syndrome [http://www.wikipathways.org/index.php/Pathway:WP3584 edit]

}}

{{clear}}{{reflist|group="§"}}

{{reflist}}Category:WikiPathways templates